WO2006050091A3 - Bioactive wound dressings and implantable devices and methods of use - Google Patents

Bioactive wound dressings and implantable devices and methods of use Download PDF

Info

Publication number
WO2006050091A3
WO2006050091A3 PCT/US2005/038925 US2005038925W WO2006050091A3 WO 2006050091 A3 WO2006050091 A3 WO 2006050091A3 US 2005038925 W US2005038925 W US 2005038925W WO 2006050091 A3 WO2006050091 A3 WO 2006050091A3
Authority
WO
WIPO (PCT)
Prior art keywords
wound dressings
dispersed
methods
precursor cells
conditioned medium
Prior art date
Application number
PCT/US2005/038925
Other languages
French (fr)
Other versions
WO2006050091A2 (en
Inventor
Kenneth W Carpenter
William G Turnell
Kristin M Defife
Kathryn A Grako
Original Assignee
Medivas Llc
Kenneth W Carpenter
William G Turnell
Kristin M Defife
Kathryn A Grako
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivas Llc, Kenneth W Carpenter, William G Turnell, Kristin M Defife, Kathryn A Grako filed Critical Medivas Llc
Priority to JP2007539165A priority Critical patent/JP2008518666A/en
Priority to AU2005302469A priority patent/AU2005302469A1/en
Priority to EP05825008A priority patent/EP1809310A4/en
Priority to CA002585740A priority patent/CA2585740A1/en
Publication of WO2006050091A2 publication Critical patent/WO2006050091A2/en
Priority to US11/796,267 priority patent/US7794706B2/en
Publication of WO2006050091A3 publication Critical patent/WO2006050091A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides wound dressings, optionally surgically implantable, containing biodegradable, polymers and hydrogels having allogenic or autologous precursor cells, such as stem cells and progenitor cells dispersed within. Alternatively, the wound dressings can have conditioned medium obtained from the precursor cells dispersed within. The wound dressings promote tissue restoration processes at a site of application or implantation. Additional bioactive agents can also be dispersed within the polymer/hydrogel matrix, which can be formulated to biodegrade at a controlled rate by adjusting the composition. Methods are also provided for using such biodegradable wound dressings as a delivery device or carrier for the precursor cells, conditioned medium and bioactive agents, or as coatings on implantable medical devices, to promote tissue restoration at a lesion site.
PCT/US2005/038925 2003-10-14 2005-10-27 Bioactive wound dressings and implantable devices and methods of use WO2006050091A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2007539165A JP2008518666A (en) 2004-10-28 2005-10-27 Bioactive wound dressings and implantable devices and methods of use
AU2005302469A AU2005302469A1 (en) 2004-10-28 2005-10-27 Bioactive wound dressings and implantable devices and methods of use
EP05825008A EP1809310A4 (en) 2004-10-28 2005-10-27 Bioactive wound dressings and implantable devices and methods of use
CA002585740A CA2585740A1 (en) 2004-10-28 2005-10-27 Bioactive wound dressings and implantable devices and methods of use
US11/796,267 US7794706B2 (en) 2003-10-14 2007-04-26 Bioactive wound dressings and implantable devices and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62344604P 2004-10-28 2004-10-28
US60/623,446 2004-10-28

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/362,848 Continuation-In-Part US7304122B2 (en) 2000-08-30 2001-08-30 Elastomeric functional biodegradable copolyester amides and copolyester urethanes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/796,267 Continuation-In-Part US7794706B2 (en) 2003-10-14 2007-04-26 Bioactive wound dressings and implantable devices and methods of use

Publications (2)

Publication Number Publication Date
WO2006050091A2 WO2006050091A2 (en) 2006-05-11
WO2006050091A3 true WO2006050091A3 (en) 2009-04-09

Family

ID=36319671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/038925 WO2006050091A2 (en) 2003-10-14 2005-10-27 Bioactive wound dressings and implantable devices and methods of use

Country Status (6)

Country Link
EP (1) EP1809310A4 (en)
JP (1) JP2008518666A (en)
CN (1) CN101437528A (en)
AU (1) AU2005302469A1 (en)
CA (1) CA2585740A1 (en)
WO (1) WO2006050091A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177416A1 (en) * 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
US7771739B2 (en) 2006-06-30 2010-08-10 Abbott Cardiovascular Systems Inc. Implantable medical devices comprising semi-crystalline poly(ester-amide)
WO2008082721A2 (en) * 2006-09-05 2008-07-10 Medivas, Llc Polymer-stabilized liposomal compositions and methods of use
EP2578081B1 (en) 2006-10-11 2016-03-09 The General Hospital Corporation Compositions, methods, and devices for treating liver disease
CA2690143A1 (en) * 2007-06-15 2008-12-24 Garnet Biotherapeutics Inc. Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro
WO2009065093A2 (en) * 2007-11-17 2009-05-22 University Of Medicine And Dentistry Of New Jersey Use of stem cells for wound healing
RU2394593C2 (en) * 2008-09-25 2010-07-20 Андрей Степанович БРЮХОВЕЦКИЙ Implanted neuroendoprosthetic system, method of obtaining it and method of carrying out reconstructive neurosurgical operation
AU2010347212B2 (en) * 2010-09-14 2016-07-14 Cell Ideas Pty Ltd Cell free preparation and uses thereof
US20140179802A1 (en) * 2011-05-02 2014-06-26 Dsm Ip Assets B.V. Fiber comprising a biodegradable polymer
ES2558357T3 (en) 2011-06-23 2016-02-03 Dsm Ip Assets B.V. Micro- or nanoparticles comprising a biodegradable polyesteramide copolymer for use in the delivery of bioactive agents
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
EP3702394B1 (en) * 2012-10-24 2023-11-22 DSM IP Assets B.V. Fibers comprising polyesteramide copolymers for drug delivery
US20170119813A1 (en) * 2014-04-08 2017-05-04 Dsm Ip Assets B.V. Biodegradable polyesteramide used for the treatment of arthritic disorders
JP6338468B2 (en) * 2014-06-19 2018-06-06 テルモ株式会社 Method for producing gel in which cells are dispersed and cell-dispersed gel produced by the method
EP3233067B1 (en) 2014-12-18 2019-11-06 DSM IP Assets B.V. Drug delivery system for delivery of acid sensitive drugs
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
CN105079859B (en) * 2015-08-20 2018-01-26 广州赛莱拉干细胞科技股份有限公司 A kind of dressing and preparation method thereof
US10322034B1 (en) 2015-09-04 2019-06-18 University Of South Florida Hydrocolloid dressing for precise nipple positioning after nipple- or skin-sparing mastectomy
CN107847643B (en) * 2016-01-17 2021-06-01 孙国明 Biocompatible polysaccharide hydrogels and methods of use
CN105709270B (en) * 2016-03-18 2019-01-01 中国科学院长春应用化学研究所 A kind of aerogel dressing for stem-cell therapy
CN106581763A (en) * 2016-12-28 2017-04-26 溯源生命科技股份有限公司 Method for preparing stem cell human miniature organs
CN110831694A (en) * 2017-03-31 2020-02-21 细尔琳生物医学公司 Biocompatible modified cell culture medium composition and uses thereof
CN107261213A (en) * 2017-06-13 2017-10-20 北京恒峰铭成生物科技有限公司 A kind of active hydrogel and preparation method thereof and the application in operation wound reparation
GB2586577B (en) * 2019-06-14 2024-03-27 Gelmetix Ltd Diagnosis and treatment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171610B1 (en) * 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
WO2002018477A2 (en) * 2000-08-30 2002-03-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6703040B2 (en) * 2000-01-11 2004-03-09 Intralytix, Inc. Polymer blends as biodegradable matrices for preparing biocomposites
JP4680483B2 (en) * 2001-02-23 2011-05-11 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション Rapid preparation of stem cell matrix for use in the treatment and repair of tissues and organs
US20060024357A1 (en) * 2004-05-12 2006-02-02 Medivas, Llc Wound healing polymer compositions and methods for use thereof
AU2004285480B2 (en) * 2003-10-22 2010-12-16 Encelle, Inc. Bioactive hydrogel compositions for regenerating connective tissue
EP1803464A4 (en) * 2004-09-17 2009-09-09 Cellgentech Inc External preparation for treating skin ulcer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171610B1 (en) * 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
WO2002018477A2 (en) * 2000-08-30 2002-03-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHUNMENG ET AL.: "Effects of Dermal Multipotent Cell Transplantation on Skin Wound Healing.", JOURNAL OF SURGICAL RESEARCH., vol. 121, September 2004 (2004-09-01), pages 13 - 19, XP002495102, DOI: doi:10.1016/j.jss.2004.04.008 *
See also references of EP1809310A4 *
YAMAGUCHI ET AL.: "Bone marrow cells differenitate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing.", BRITISH JOURNAL OF DERMATOLOGY., vol. 152, 2005, pages 616 - 622, XP008119299 *

Also Published As

Publication number Publication date
CN101437528A (en) 2009-05-20
JP2008518666A (en) 2008-06-05
CA2585740A1 (en) 2006-05-11
EP1809310A2 (en) 2007-07-25
AU2005302469A1 (en) 2006-05-11
EP1809310A4 (en) 2011-10-26
WO2006050091A2 (en) 2006-05-11

Similar Documents

Publication Publication Date Title
WO2006050091A3 (en) Bioactive wound dressings and implantable devices and methods of use
Shirzaei Sani et al. Engineering adhesive and antimicrobial hyaluronic acid/elastin-like polypeptide hybrid hydrogels for tissue engineering applications
Tran et al. Citrate-based biomaterials and their applications in regenerative engineering
Li et al. Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model
Lakes et al. Synthesis and characterization of an antibacterial hydrogel containing covalently bound vancomycin
US8932614B2 (en) Incorporation of particulate ceragenins in polymers
US20140271761A1 (en) Incorporation of particulate ceragenins in polymers
WO2007038246A3 (en) Solid polymer delivery compositions and methods for use thereof
ES2644478T3 (en) Cochlear drug-releasing implants
WO2013029055A1 (en) Incorporation of particulate ceragenins in polymers
Wang et al. Polyurethane for biomedical applications: A review of recent developments
WO2007056134A3 (en) Resorbable phenolic polymers
MXPA05013003A (en) Implantable elastomeric depot compositions, uses thereof and method of manufacturing.
TW200503774A (en) Controlled release depot formulations
ATE510570T1 (en) MICRO-ENCAPSULATED COMPOSITIONS FOR ENDOLUMINAL TISSUE CONSTRUCTION
WO2008054772A3 (en) Implantable elastomeric caprolactone depot compositions and uses thereof
Guo et al. A transient cell-shielding method for viable MSC delivery within hydrophobic scaffolds polymerized in situ
WO2002039948A3 (en) Cross-linked hyaluronic acid-laminin gels and use thereof in cell culture and medical implants
DE602005018178D1 (en) PHOSPHOLIPIDE AND POLLUTION-RESISTANT COATING COMPOSITIONS
CA2602905A1 (en) Photocrosslinkable oligo(poly (ethylene glycol) fumarate) hydrogels for cell and drug delivery
WO2011022680A2 (en) Wound dressings, methods of using the same and methods of forming the same
WO2007001624A3 (en) Medical and dental implant devices for controlled drug delivery
EP2309990A4 (en) Drug loaded polymeric nanoparticles and methods of making and using same
WO2005097228A3 (en) Coating compositions for bioactive agents
EP2617440A3 (en) Medical implants and methods for delivering biologically active agents

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200580041430.7

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KN KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 11796267

Country of ref document: US

Ref document number: 2005302469

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2585740

Country of ref document: CA

Ref document number: 2007539165

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 3323/DELNP/2007

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2005825008

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2005302469

Country of ref document: AU

Date of ref document: 20051027

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2005825008

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 11796267

Country of ref document: US