WO2006012577A3 - Derives de la quinazolinone utiles pour la regulation de l'homeostasie du glucose et de prise d'aliments - Google Patents
Derives de la quinazolinone utiles pour la regulation de l'homeostasie du glucose et de prise d'aliments Download PDFInfo
- Publication number
- WO2006012577A3 WO2006012577A3 PCT/US2005/026192 US2005026192W WO2006012577A3 WO 2006012577 A3 WO2006012577 A3 WO 2006012577A3 US 2005026192 W US2005026192 W US 2005026192W WO 2006012577 A3 WO2006012577 A3 WO 2006012577A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- regulation
- food intake
- quinazolinone derivatives
- derivatives useful
- glucose homeostasis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59080404P | 2004-07-22 | 2004-07-22 | |
US60/590,804 | 2004-07-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006012577A2 WO2006012577A2 (fr) | 2006-02-02 |
WO2006012577A3 true WO2006012577A3 (fr) | 2006-09-28 |
Family
ID=35786753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/026192 WO2006012577A2 (fr) | 2004-07-22 | 2005-07-22 | Derives de la quinazolinone utiles pour la regulation de l'homeostasie du glucose et de prise d'aliments |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006012577A2 (fr) |
Families Citing this family (31)
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---|---|---|---|---|
EP1838296B1 (fr) | 2004-10-20 | 2012-08-08 | Resverlogix Corp. | Flavanoides et isoflavanoides pour la prevention et le traitement de maladies cardio-vasculaires |
CA2636981A1 (fr) * | 2006-01-31 | 2007-08-09 | F. Hoffmann-La Roche Ag | 7h-pyrido[3,4-d]pyrimidin-8-ones, leur fabrication et leur utilisation en tant qu'inhibiteurs des proteines kinases |
ATE523500T1 (de) * | 2006-09-11 | 2011-09-15 | Organon Nv | Chinazolinon- und isochinolinon-acetamid-derivate |
JP5236664B2 (ja) | 2007-02-01 | 2013-07-17 | レスバーロジックス コーポレイション | 心血管疾患を予防および治療するための化合物 |
CN101531638B (zh) * | 2008-03-13 | 2011-12-28 | 中国科学院广州生物医药与健康研究院 | 用作***相关受体调节剂的化合物及其应用 |
AU2009249237A1 (en) | 2008-05-19 | 2009-11-26 | Schering Corporation | Bicyclic heterocycle derivatives and use thereof as GPR119 modulators |
AU2009262252B2 (en) * | 2008-06-26 | 2013-05-02 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
CN101628913B (zh) | 2008-07-18 | 2013-01-23 | 中国科学院广州生物医药与健康研究院 | 用作***相关受体调节剂的化合物及其应用 |
FR2938538B1 (fr) * | 2008-11-17 | 2011-08-05 | Univ Nice Sophia Antipolis | Procede de preparation d'acides et d'esters boroniques en presence de magnesium metallique |
JP2012051803A (ja) * | 2008-12-25 | 2012-03-15 | Kyorin Pharmaceutical Co Ltd | 環状アミノ安息香酸エステル誘導体の製造方法 |
JP5635535B2 (ja) | 2009-01-08 | 2014-12-03 | レスバーロジックス コーポレイション | 心血管疾患の予防および治療のための化合物 |
NZ595747A (en) | 2009-03-18 | 2015-06-26 | Resverlogix Corp | Novel quinazolinones and related compounds for use as anti-inflammatory agents |
DK2421533T3 (en) | 2009-04-22 | 2019-01-07 | Resverlogix Corp | Hitherto unknown anti-inflammatory agents |
WO2011075699A2 (fr) | 2009-12-18 | 2011-06-23 | Sunovion Pharmaceuticals Inc. | Composés pour le traitement des troubles médiés par le récepteur métabotropique 5 du glutamate, et leurs méthodes d'utilisation |
GB201004739D0 (en) * | 2010-03-22 | 2010-05-05 | Prosidion Ltd | Receptor modulators |
EP2766349B1 (fr) | 2011-03-08 | 2016-06-01 | Sanofi | Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
WO2012120054A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2565186A1 (fr) * | 2011-09-02 | 2013-03-06 | Hybrigenics S.A. | Inhibiteurs sélectifs et réversibles de la protéase 7 spécifique de l'ubiquitine |
CN103945848B (zh) | 2011-11-01 | 2016-09-07 | 雷斯韦洛吉克斯公司 | 被取代的喹唑啉酮的口服即释制剂 |
US9765039B2 (en) | 2012-11-21 | 2017-09-19 | Zenith Epigenetics Ltd. | Biaryl derivatives as bromodomain inhibitors |
US9073878B2 (en) | 2012-11-21 | 2015-07-07 | Zenith Epigenetics Corp. | Cyclic amines as bromodomain inhibitors |
CN105073744B (zh) | 2012-12-21 | 2019-11-08 | 齐尼思表观遗传学有限公司 | 作为溴结构域抑制剂的新型杂环化合物 |
GB201313664D0 (en) | 2013-07-31 | 2013-09-11 | Univ Cardiff | Bcl-3 inhibitors |
CN107530356A (zh) | 2015-03-13 | 2018-01-02 | 雷斯韦洛吉克斯公司 | 用于治疗补体相关疾病之组合物及治疗方法 |
US10675283B2 (en) | 2017-03-24 | 2020-06-09 | University Of South Florida | Compositions and methods for white to beige adipogenesis |
WO2018184115A1 (fr) * | 2017-04-06 | 2018-10-11 | London Health Sciences Centre Research Inc. | Dérivés de quinazolinone utiles pour l'imagerie |
WO2019104324A1 (fr) * | 2017-11-27 | 2019-05-31 | The Scripps Research Institute | Antagoniste de ghsr1a pour le traitement du syndrome de prader-willi |
CN110698392A (zh) * | 2019-09-09 | 2020-01-17 | 中国农业大学 | 一种双酰胺类化合物及其制备方法与应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998033792A1 (fr) * | 1997-01-31 | 1998-08-06 | Kyowa Hakko Kogyo Co., Ltd. | Derives de la piperidine |
US6337332B1 (en) * | 1998-09-17 | 2002-01-08 | Pfizer Inc. | Neuropeptide Y receptor antagonists |
-
2005
- 2005-07-22 WO PCT/US2005/026192 patent/WO2006012577A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998033792A1 (fr) * | 1997-01-31 | 1998-08-06 | Kyowa Hakko Kogyo Co., Ltd. | Derives de la piperidine |
US6337332B1 (en) * | 1998-09-17 | 2002-01-08 | Pfizer Inc. | Neuropeptide Y receptor antagonists |
Non-Patent Citations (1)
Title |
---|
BAKER B.R. ET AL.: "An Antimalarial Alkaloid From Hydrangea. IV. Functional Derivatives of 3-Alkyl-4-Quinazolones", J. ORG. CHEM., vol. 17, 1952, pages 35 - 51 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006012577A2 (fr) | 2006-02-02 |
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