WO2005121780A3 - Methods and apparatus for characterizing, measuring, and dispensing fluids - Google Patents

Methods and apparatus for characterizing, measuring, and dispensing fluids Download PDF

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Publication number
WO2005121780A3
WO2005121780A3 PCT/US2004/041444 US2004041444W WO2005121780A3 WO 2005121780 A3 WO2005121780 A3 WO 2005121780A3 US 2004041444 W US2004041444 W US 2004041444W WO 2005121780 A3 WO2005121780 A3 WO 2005121780A3
Authority
WO
WIPO (PCT)
Prior art keywords
characterizing
methods
measuring
dispensing
fluids
Prior art date
Application number
PCT/US2004/041444
Other languages
French (fr)
Other versions
WO2005121780A2 (en
Inventor
Peter R C Gascoyne
Jody V Vykoukal
Christian Girardet
Jamileh Noshari
Ulrich Mueller
Original Assignee
Univ Texas
Peter R C Gascoyne
Jody V Vykoukal
Christian Girardet
Jamileh Noshari
Ulrich Mueller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Peter R C Gascoyne, Jody V Vykoukal, Christian Girardet, Jamileh Noshari, Ulrich Mueller filed Critical Univ Texas
Publication of WO2005121780A2 publication Critical patent/WO2005121780A2/en
Publication of WO2005121780A3 publication Critical patent/WO2005121780A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0237—Details of electronic control, e.g. relating to user interface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects thereof, e.g. conductivity or capacity
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • G01N2015/1024—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1062—General features of the devices using the transfer device for another function for testing the liquid while it is in the transfer device

Abstract

The invention is directed to methods and an apparatus for characterizing, measuring, and dispensing fluids. Pipettor system (10) is described as including sensors in or near the tip (14) for sensing parameters useful for fluid handling. In a respective embodiment, a pipettor can include an integral impedance sensor useful for counting particles and/or calculating particle concentration. Such information can be used in the dispensing of fluids and avoids the need for additional measuring equipment.
PCT/US2004/041444 2003-12-09 2004-12-09 Methods and apparatus for characterizing, measuring, and dispensing fluids WO2005121780A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52809103P 2003-12-09 2003-12-09
US60/528,091 2003-12-09

Publications (2)

Publication Number Publication Date
WO2005121780A2 WO2005121780A2 (en) 2005-12-22
WO2005121780A3 true WO2005121780A3 (en) 2006-05-11

Family

ID=35503768

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/041444 WO2005121780A2 (en) 2003-12-09 2004-12-09 Methods and apparatus for characterizing, measuring, and dispensing fluids

Country Status (1)

Country Link
WO (1) WO2005121780A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2887982B1 (en) * 2005-07-01 2009-03-06 Biomerieux Sa AUTOMATIC PIPETTING DEVICE FOR ENSURING THE TRACEABILITY OF THE REALIZED ANALYSIS
US20080269581A1 (en) 2007-04-24 2008-10-30 Kim Wood Method and apparatus for measuring blood volume
US8033188B2 (en) 2007-09-17 2011-10-11 Integra Biosciences Corp. Pipettor software interface
US8015887B2 (en) * 2007-09-29 2011-09-13 E I Spectra, LLC Instrumented pipette tip
KR101670621B1 (en) * 2007-10-02 2016-10-28 테라노스, 인코포레이티드 Modular point-of-care devices and uses thereof
EP2214833A4 (en) * 2007-11-27 2012-11-14 El Spectra Llc Fluorescence-based pipette instrument
DE102008048620B4 (en) * 2008-09-23 2011-09-15 Ahn Biotechnologie Gmbh Electronic piston stroke pipette
US9470616B2 (en) * 2009-04-27 2016-10-18 E.I. Spectra, Llc Pipette instrument
GB2470014A (en) * 2009-05-05 2010-11-10 Medermica Ltd pH measurement device
US8602644B2 (en) * 2009-05-08 2013-12-10 University Of North Texas Multifunctional micropipette biological sensor
US8790592B2 (en) * 2010-02-04 2014-07-29 Bio-Rad Laboratories, Inc. Measuring multi-analyte samples using an in-line flow cell
JP5945282B2 (en) 2011-01-21 2016-07-05 セラノス， インコーポレイテッド System and method for maximizing sample usage
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
DE102012209314B4 (en) 2012-06-01 2015-04-02 Albert-Ludwigs-Universität Freiburg Device and method for dispensing or receiving a liquid volume
DK3058337T3 (en) 2013-10-15 2019-04-15 Ecole Polytechnique Fed Lausanne Epfl MEASUREMENT TIP WITH ELECTRIC IMPEDANCE SENSOR
EP3283221B1 (en) 2015-04-15 2022-09-07 Ecole Polytechnique Fédérale de Lausanne (EPFL) Devices, systems and methods for dispensing and analysing particles
US10144537B2 (en) 2016-11-30 2018-12-04 Mallinckrodt Nuclear Medicine Llc Systems and methods for dispensing radioactive liquids
JP2018164866A (en) * 2017-03-28 2018-10-25 株式会社アイカムス・ラボ Portable terminal device and program

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5855851A (en) * 1996-07-19 1999-01-05 Hitachi, Ltd. Apparatus for trasferring liquid having liquid level sensing function
US6132582A (en) * 1998-09-14 2000-10-17 The Perkin-Elmer Corporation Sample handling system for a multi-channel capillary electrophoresis device
US20020009392A1 (en) * 2000-03-28 2002-01-24 Wolk Jeffrey A. Methods of reducing fluid carryover in microfluidic devices
US6372185B1 (en) * 1997-05-16 2002-04-16 Aurora Biosciences Corporation Liquid chemical distribution method and apparatus
US6605475B1 (en) * 1999-04-16 2003-08-12 Perspective Biosystems, Inc. Apparatus and method for sample delivery

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5855851A (en) * 1996-07-19 1999-01-05 Hitachi, Ltd. Apparatus for trasferring liquid having liquid level sensing function
US6372185B1 (en) * 1997-05-16 2002-04-16 Aurora Biosciences Corporation Liquid chemical distribution method and apparatus
US6132582A (en) * 1998-09-14 2000-10-17 The Perkin-Elmer Corporation Sample handling system for a multi-channel capillary electrophoresis device
US6605475B1 (en) * 1999-04-16 2003-08-12 Perspective Biosystems, Inc. Apparatus and method for sample delivery
US20020009392A1 (en) * 2000-03-28 2002-01-24 Wolk Jeffrey A. Methods of reducing fluid carryover in microfluidic devices

Also Published As

Publication number Publication date
WO2005121780A2 (en) 2005-12-22

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