WO2005092412A1 - Adapter und pumpeninterface zur druckmessung für eine infusionspumpe - Google Patents
Adapter und pumpeninterface zur druckmessung für eine infusionspumpe Download PDFInfo
- Publication number
- WO2005092412A1 WO2005092412A1 PCT/EP2004/014732 EP2004014732W WO2005092412A1 WO 2005092412 A1 WO2005092412 A1 WO 2005092412A1 EP 2004014732 W EP2004014732 W EP 2004014732W WO 2005092412 A1 WO2005092412 A1 WO 2005092412A1
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- WO
- WIPO (PCT)
- Prior art keywords
- adapter
- pump
- membrane
- plunger
- pump interface
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
- A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
Definitions
- the invention relates to an adapter and a pump interface for pressure measurement for an infusion pump.
- the invention relates to an adapter and a pump interface for pressure measurement for an infusion pump, which are used for occlusion detection and / or leak detection.
- the exact dosage of the product dose administered is of great importance, in particular in the case of dosed administration to humans.
- the monitoring of the correct product administration is desirable, if not essential.
- One way of monitoring is to monitor the pressure of the product fluid, since if the mechanical and electronic components of an infusion or injection device are functioning properly, it can be concluded that the product is being administered properly, as long as the fluid pressure maintains a predetermined pressure range. If this is not observed, an occlusion or a leak in the fluid management system can be concluded.
- Various designs of infusion pumps, as well as various methods for pressure measurements and for occlusion detection / leakage detection are known from the prior art.
- a method for pressure measurement is known from US-A-4,373,525, the change in the outer diameter of an elastic tube through which a fluid intended for infusion lies is detected.
- the change in outside diameter is related to the change in fluid pressure in the elastic tube.
- DE 38 71 721 T2 extends the method known from US-A-4,373,525 to the effect that when a predefined threshold value is exceeded, the infusion pump is stopped within a defined time interval and an alarm signal is triggered.
- a pressure sensor for infusion lines is known, which is used to determine the media pressure in an elastic hose section.
- a pressure element acts on a beam fixed on one side, which carries an influencing part at its free end.
- This influencing part is a core in a coil arrangement, the position of the core changing the frequencies of the voice coils. Numerous measured pressure values are recorded at regular time intervals and then averaging takes place to achieve a representative pressure value.
- a pressure sensor arrangement which is assigned to a drive device for driving a disposable pump cassette, which has a pressure sensor and a position detection device, the pressure sensor having an elongate, longitudinally movable, rod-shaped part with one end, which is of such a type is configured such that it can contact the pressure detection part of the cassette, the rod-shaped part being designed such that it can move in response to a change in the pressure in the cassette, which further comprises a flexible support for storing the elongated rod-shaped part, which can bend depending on the movement of the rod, and has a position detection device which makes the flexible carrier assignable for monitoring the bending movement of the carrier, characterized in that the flexible carrier has a first a flexible support which is fixedly fixed in the transverse direction of the rod-shaped part and a second flexible support which supports a second end of the elongated rod-shaped part, the first flexible support being arranged between the first and the second end of the rod-shaped part that the bending the first and second
- a method for monitoring the pressure of a product fluid to be administered in doses during an infusion or injection is known, which is made from a container which is accommodated in a housing or is formed by this, by advancing one in the Received piston container can be poured out.
- a reaction force exerted by the piston on the housing as a measure of the pressure is measured and fed to a controller for driving the piston.
- the control compares the measured reaction force with a predefined comparison force and controls the drive of the piston taking into account the comparison result.
- the comparison force is a target value for the reaction force and a direct target / actual comparison is carried out between the measured reaction force and its target value.
- the invention further relates to a device which is particularly suitable for carrying out this method.
- the object of the invention is to provide an adapter and a pump interface for pressure measurement for an infusion pump, with the aid of which pressure measurement or occlusion detection and / or leak detection can be carried out extremely reliably and quickly.
- the degree of complexity should be significantly reduced, which leads to lower manufacturing costs.
- An adapter according to the invention for measuring pressure for an infusion pump can, for example, be placed on the infusion pump and comprises a fluid channel and an insert.
- a liquid active ingredient solution can be used as the fluid, the path of the fluid being determined by the fluid channel.
- the fluid channel has a connection possibility to an ampoule and a connection possibility to an infusion set.
- the ampoule is a storage container for the fluid and the infusion set enables the fluid to be infused into a recipient, for example a patient. If the infusion pump and the infusion set function properly, a fluid flows out of the ampoule through the fluid channel to the infusion set, the fluid being pumped from the ampoule to the infusion set or being displaced from the ampoule.
- the insert of the adapter according to the invention has a surface which is in contact with the fluid channel, for example can form a boundary of the fluid channel.
- the insert can be made from a single material or from several different materials or composite materials. If the surface of the insert, which is in contact with the fluid channel, is formed by a certain part of the insert, which can be characterized materially or functionally, for example a coating, then this is understood to mean that the insert in contact with the fluid channel according to the invention is.
- the insert is movable in its entirety or at least partially and can be deflected from a rest position. The rest position is defined as the position in which the insert is when it is not subjected to any force due to the pressure of a fluid.
- the fluid pressure in the fluid channel is transmitted directly to the insert via its surface, and its surface, which is in contact with the fluid channel, serves as the active surface.
- the insert can consist of one or more individual parts. These can be rigid or elastic.
- the fluid channel of an adapter according to the invention preferably has a rigid wall. This rigid wall is advantageous because, in the event of an increase in pressure, the fluid pressure can be better transmitted to the insert or its active surface.
- elastic walls there is a risk that they could expand excessively when the pressure inside the fluid increases, which could lead to the fluid pressure being delayed or increasing less overall, even though there is already an occlusion or partial blockage. This can prevent a quick and reliable detection of an occlusion.
- the fluid channel has a chamber.
- the dimensions of this chamber can differ from the rest of the fluid channel; for example, its cross section can be shorter than that of the rest of the fluid channel. It is advantageous here if the volume of the chamber is kept relatively small. If the overall fluid path is as short as possible or the volume of the entire fluid channel is small, occlusion and / or leakage can be detected particularly quickly and reliably. Accordingly, the chamber must be prevented from having an excessively large dead volume, that is to say that the filling volume of the entire fluid channel is not unduly increased. The smaller a volume, the faster a pressure increase can be detected in it.
- the insert is arranged in the chamber.
- the underside of the chamber can be formed by the insert.
- its surface can be made relatively large and flat in order to optimally take over the fluid pressure with its active surface.
- the insert comprises a plunger and / or an adapter membrane.
- the plunger is preferably made of a rigid material
- the adapter membrane is preferably elastic and preferably has a low intrinsic stiffness.
- the surface of the insert, which is in contact with the fluid channel, is preferably formed by the plunger.
- the adapter membrane can with be in contact with the fluid channel. In an advantageous embodiment of the invention, it serves for the elastic mounting of the tappet.
- the elastically mounted plunger of the insert can be deflected from its rest position, for example, by an increased pressure of the fluid.
- the adapter membrane can be firmly connected to the adapter in partial areas so that these areas are not deflected. These sub-areas can also perform a sealing function.
- the tappet is designed as a T-tappet. It therefore has an elongated, e.g. cylindrical part, as well as a wider attachment piece.
- the T-plunger preferably has symmetry with respect to an axis or point reflection.
- the center of reflection is preferably on the longitudinal axis of the plunger.
- the plunger can have rotational symmetry, and it can also have a square or rectangular cross section.
- the plunger should preferably be designed in such a way that, due to the fluid pressure that is transferred to the surface of the plunger, the T-plunger does not tilt or wedge, but rather that it extends along a e.g. straight axis can move out of its rest position.
- This axis preferably points in the direction of a pump interface according to the invention.
- the adapter membrane is approximately U-shaped in cross-section and preferably has an annular circumference around the tappet.
- the force that acts on the tappet is, for example, directly proportional to the prevailing fluid pressure.
- the adapter membrane is bent, for example, in a predetermined manner.
- the adapter membrane is only slightly deformed, ie the pressure energy of the fluid is only converted to a small extent into deformation work. Instead, it is practically completely available for moving the tappet, which enables a more precise determination of the fluid pressure, in particular the adapter membrane is practically not stretched in this embodiment.
- the adapter membrane can rest along the stretched part of the T-tappet and / or at the same time below the T-piece. It is thus, for example, formed in a ring-shaped manner around a region of the tappet that does not have the maximum diameter of the tappet, as a result of which, for example, a seal can also be realized.
- the invention relates to a pump interface with a sensor that can be coupled to the insert of an adapter.
- a coupling can be a mechanical contact, for example.
- the sensor serves to determine the fluid pressure of a fluid whose corresponding pressure or force effect has been transferred to the insert of an adapter.
- pressure sensors can be, for example, pressure-sensitive microchips with an integrated bridge circuit. Their small size is advantageous.
- Pressure sensors can, for example, be provided with a gel in the housing above the die in order to protect the sensitive microchip and to ensure an even distribution of force. They are therefore suitable, for example, for measuring gas and liquid pressures.
- Some sensors are also spring-loaded in the housing with a soft adhesive. When pressurized, they can dodge to a small extent or change their position, which is advantageous in the case of mechanical contacting by a solid. A stiff, immobile sensor surface is often not available. Care should also be taken to contact the microchip in parallel or even on a small area such as 1 mm 2 .
- a strain gauge is deformed on a bending beam.
- Such a strain gauge is installed, for example, in a Wheatstone bridge. A voltage change that is proportional to the force acting can be detected. Because the bending beam is pressed against a base plate or a stop at maximum force, there is little or no risk of destruction due to overload.
- the pump interface comprises a transmission piece, via which the insert piece of the adapter can be coupled to the sensor, for example mechanically or magnetically.
- the transmission piece can have a solid or non-solid state of matter. It can be made in one part or in several parts, it can be rigid and / or elastic.
- the transmission piece can be deflected in whole or in part from a rest period. In the rest position, no external forces act on the transmission piece.
- the coupling of the transmission piece with the insert piece can take place, for example, in the solid state of aggregation over a surface which ensures the best possible transmission of force from the insert piece of the adapter to the transmission piece. In the case of a point contact, the adjustment should be more precise.
- the transmission piece comprises a counter tappet and / or a pump membrane.
- the counter tappet is advantageously made of a rigid material.
- the pump membrane is preferably elastic and preferably has a low intrinsic stiffness.
- the counter plunger of the transmission piece can have the same properties and embodiments as the plunger of the insert piece of an adapter according to the invention.
- the pump membrane of the transfer piece can have the same properties and features as the adapter membrane of the insert piece of an adapter according to the invention.
- the counter tappet is designed as a dumbbell-shaped counter tappet.
- the dumbbell-shaped counter plunger has, for example, an elongated e.g. cylindrical part, as well as a wider attachment piece.
- the counter plunger is symmetrical.
- the center of symmetry can lie along a longitudinal axis of the counter tappet for the counter tappet.
- the counter tappet can be rotational symmetry and can be square or have a rectangular cross section.
- the counter-plunger is preferably designed in such a way that when the force is transmitted from the insert of an adapter to the counter-plunger, no tilting and / or tilting of the counter-plunger occurs, but rather that it can be moved without problems along a predetermined, for example, straight axis.
- the pump interface is advantageously designed such that the pump membrane ensures the elastic mounting of the counter-plunger.
- the pump membrane can also be firmly clamped into the pump interface at an edge area. The clamped part of the pump membrane is therefore immovable or cannot be displaced from a rest position like the counter-plunger.
- the pump interface according to the invention is preferably designed in such a way that the pump diaphragm is U-shaped in cross-section and is designed in a ring shape around the counter-plunger.
- the U-shape of the cross section or the angled embodiment of the pump membrane means that the pump membrane is practically only bent and not stretched and thus deformed under the action of the counter-plunger connected to it. There is practically no deformation work to be done here, and the entire force acting on the counter-plunger can be used to move the counter-plunger.
- the pump membrane is designed in a ring shape around a region of the counter-plunger that does not have the maximum diameter of the counter-plunger.
- the pump interface advantageously has at least one protection against accidental contact to protect the pump diaphragm and / or the sensor against contact. Touching could result in damage to the pump membrane, for example, or the sensor could be damaged.
- a protection against accidental contact to protect the pump diaphragm is advantageously designed in the form of brackets, so that contact with the pump diaphragm and / or the sensor is preferably prevented while the adapter is being replaced. These brackets can be formed parallel to each other at a certain distance, which, for example, makes contact with a finger impossible. However, you could also cross each other. They can be straight or curved.
- the senor is on a print and is held by a sensor holder. This facilitates a sufficient and exact fixation of the sensor, so that an optimal pressure measurement or force measurement can be carried out with the sensor.
- the print can snap into the sensor holder in a defined manner.
- Other types of fastening are also possible, for example gluing or screwing.
- the invention relates to a pump with an adapter according to the invention and with a pump interface according to the invention as described above.
- the pump thus has at least one interchangeable adapter for pressure measurement with a fluid channel and with an insert, the fluid channel being able to connect to a z. B. arranged in a pump ampoule and a connection to an infusion set, and wherein the insert has a surface which is in contact with the fluid channel and which can be deflected from a rest position.
- the pump has at least one pump interface with a sensor that can be coupled to the insert of an adapter.
- an ampoule which contains the fluid to be administered can be inserted into the pump.
- the pump according to the invention comprises a pump device.
- This pump device includes, for example, a stopper, a threaded rod and a motor.
- the stopper is advantageously located in the ampoule, for example it forms the bottom of a cylindrical ampoule.
- the stopper can be moved within the ampoule by means of a threaded rod which is driven by a motor. By moving the stopper in the ampoule, the fluid is pressed out of the ampoule.
- the fluid channel is advantageously connected to the ampoule via a cannula formed on the fluid channel of the adapter. This cannula can be passed through a septum that closes the ampoule. This ensures a safe and clean connection.
- the fluid channel is advantageously connected to the infusion set through a luer which is enclosed in the adapter.
- a luer enables a secure and stable connection of an inherently fragile section of the infusion set to the fluid channel of the adapter.
- other connection options are also possible.
- a pump according to the invention advantageously has an adapter membrane and a pump membrane. If the adapter is placed on the pump interface, the adapter membrane and the pump membrane are advantageously slightly prestressed against one another, so that approximately a compensation of the inherent rigidity of the adapter and pump membrane is achieved in the zero position. In the zero position there is a balance of forces.
- the compensation of the inherent stiffnesses means that when the diaphragm or the parts connecting it, such as insert and transfer piece, move due to an additional external force or an additional external pressure, such as the fluid pressure, these are used entirely to shift the insert or transfer piece can be. No energy is therefore used to overcome the inherent stiffness of the adapter and / or pump membrane.
- the inherent rigidity of the pump membrane is less or greater than that of the adapter membrane. Accordingly, the preload path of the pump membrane is chosen to be larger or smaller than that of the pump membrane.
- the invention relates to the use of the adapter for detecting an occlusion and / or a leak.
- An occlusion refers to a blockage or partial narrowing of the fluid path to an infusion set.
- the Occlusion is noticeable by an increase in pressure within the fluid channel, and can therefore be detected by an adapter according to the invention and by a pump interface according to the invention as described above by a pressure measurement.
- An occlusion occurs when the measured fluid pressure exceeds a previously specified target value.
- Leakage i.e. an undesired loss of fluid product, occurs when the measured fluid pressure falls below a minimum value previously specified in this regard.
- the invention relates to a method for detecting an occlusion and / or a leak using an adapter according to the invention and using a pump interface as described above.
- a pressure measurement can be made at any time e.g. be carried out by a single measurement.
- the time of this individual measurement is advantageously independent of possible interval distributions of a liquid drug.
- the single measurement enables the immediate detection of a possible occlusion or leak.
- the method according to the invention thus works extremely quickly and reliably.
- the invention relates to a further method for detecting an occlusion and / or leak using an adapter according to the invention and using a pump interface according to the invention as described above.
- the fluid pressure is, in good approximation with respect to the measuring accuracy of the sensor, proportional to the force that presses on the sensor. This can be achieved, for example, by prestressing the adapter membrane and the pump membrane against each other when the adapter is placed on the pump interface in such a way that approximately a compensation of the inherent stiffness of the adapter and pump membrane is achieved.
- a corresponding proportionality of the fluid pressure to the force that presses on the sensor can also be achieved in that a membrane, which ensures elastic mounting of a tappet, is U-shaped in cross section and has an annular circumference around the tappet.
- the deflected rigid plunger presses on the sensor.
- the special shape of the membrane e.g. its U-shaped cross-section or more generally its properties due to its angled structure, ensures that when the tappet moves, the membrane is only bent and is not significantly deformed or stretched. No additional pressure energy is converted into deformation work of the membrane, so that all energy can be used to move the tappet.
- the direct proportionality of the fluid pressure to the force acting on the sensor is guaranteed.
- FIG. 1 shows a cross section through an adapter.
- FIG. 2A shows a perspective cross section through a pump interface
- 2B is a perspective top view of the pump interface
- Fig. 6 is a diagram for the compensation of inherent stiffness of two memes
- Fig. 7 shows a pump with adapter and pump interface.
- the fluid channel 1 shows a cross section through an adapter 1 according to the invention. It has a fluid channel 2 and an insert 5.
- the fluid channel 2 has a connection option 3 to an ampoule and a connection option 4 to an infusion set.
- the connection option 3 to an ampoule comprises a cannula 9
- the connection option 4 to an infusion set comprises a part 10 of the fluid channel to which a luer is connected with a corresponding luer thread 11.
- the fluid channel has a chamber 8 to which the insert 5 adjoins on the underside.
- the fluid channel course shown can be described as follows:
- the insert 5 comprises a T-plunger 6 and an adapter membrane 7.
- the adapter membrane 7 is connected to the T-plunger below the T-piece of the T-plunger 6.
- the adapter membrane 7 ensures the elastic mounting of the T-plunger 6.
- the adapter membrane 7 has a U-shaped cross-section and is designed to be ring-shaped and sealing around the T-plunger.
- the T-plunger 6 is rigid, the adapter membrane 7 has a low inherent rigidity. Both are made of plastic.
- the U-shaped cross section of the adapter membrane 7 and its attachment below the T-piece of the T-plunger 6 allows the T-plunger to deflect downwards perpendicularly to the fluid channel when pressure is exerted by the fluid, with practically all the pressure energy being involved in the movement work of the T- Tappet flows, there is practically no additional deformation work in the adapter membrane 7.
- a direct proportional relationship results between the fluid pressure in the chamber 8 and the force with which the T-plunger 6 is pressed downward.
- the pump interface 18 has a sensor 20 which can be coupled to the insert 5 of an adapter 1.
- the sensor 20 is located on a print 22, the print 22 is held by a sensor holder 23. In this case, the print 22 has been snapped onto the sensor 23.
- the pump interface 18 has a transmission piece 19.
- the transmission piece 19 is composed of a counter plunger 21 and a pump membrane 24.
- the counter plunger 21 has a notch and is made of a rigid material.
- the pump membrane 24 is elastic and has a relatively low inherent rigidity.
- the U-shaped pump membrane 24 is designed to run circumferentially around the counter-plunger 21. It engages with the constriction in the counter plunger 21.
- This embodiment of the pump diaphragm 24 and counter plunger 21 ensures that when a force is transmitted to the counter plunger 21 through the insert 5 of an adapter 1 according to the invention, the force acting is used practically exclusively for the movement of the counter plunger 21; no additional energy is required to the pump diaphragm 24 to perform deformation work.
- the pump diaphragm 24 and the sensor 20 are protected against contact and / or damage by a touch guard 25.
- the contact protection 25 is designed in the form of brackets.
- a first adapter connection rail 32 and a second adapter connection rail 29 are designed in the form of a circular arc.
- an ampoule shaft sleeve 32 can be seen, into which an ampoule can be screwed.
- a battery 26 is provided, which is located in a battery well sleeve 28. It is closed by a battery cover 27.
- FIG. 2B shows a perspective top view of the pump interface 18, which had already been shown in cross-section in FIG. 2A.
- the top of the counter-plunger 31 can be seen in a circle, which is encircled by the pump membrane 24 in a ring-shaped manner.
- the first adapter connection rail 32 and the second adapter connection rail 29 can also be clearly seen, the ampoule shaft sleeve 32 can be seen on the left, and the battery cover 27 is shown in a plan view on the right.
- FIG. 3A shows cross-section the deformation and expansion of a membrane 40a under the action of force 42.
- the membrane is clamped on the sides 41, otherwise it can move freely under the action of force 42.
- the result of the action of force 42 can be divided into two components: on the one hand there is a slight deflection 43a of the membrane 40a in the direction of the acting force 42, on the other hand the upper area of the membrane 40a stretched, for the expansion 45 deformation work is to be done.
- the force required for the deformation work comes from the acting force 42.
- FIG. 3B shows another situation in which a T-plunger 44 is elastically supported by a membrane 40b.
- the situation is shown in cross-section.
- the membrane 40b has a U-shaped cross section. It bears on both sides of the T-plunger 44 below its T-piece 47, or in the three-dimensional view it is formed in a ring around the T-plunger 44.
- An external force 42 acts on the T-piece 47 of the T-plunger 44.
- the direction of the force 42 is oriented perpendicular to the surface of the T-piece 47 of the T-plunger 44. Under the action of force 42, the T-plunger 44 is moved downward along the X-axis 46.
- the membrane 40b with the aid of which the T-plunger 44 is mounted elastically, is practically not stretched here, and no portion of the force 42 is required to apply energy to deform the membrane 40b.
- the entire force 42 is available for the downward movement 43b of the T-plunger 44.
- a design according to the rules of FIG. 3b thus enables the fluid pressure to be in good approximation with respect to the measuring accuracy of a sensor, which is proportional to the force that presses on the sensor.
- both the insert 5 of an adapter 1 according to the invention and the transmission piece 19 of a pump interface 18 according to the invention are equipped with a membrane.
- the adapter membrane 7 and the pump membrane 24 can have different properties.
- 5A-C show principle sketches of membranes biased against each other.
- the forces that occur are indicated by arrows.
- the upper striped arrows 61a, 61b and 61c each denote a membrane force 1
- the arrows 62a, 62b and 62c each denote a membrane force 2.
- Fig. 5A the membrane force 1 61a and the membrane force 2 62a are in equilibrium with each other.
- the system is in the zero position 60a. In this case, no other external forces act on the system.
- FIG. 5B in addition to the downward membrane force 1 61b and the upward membrane force 2 62b, an external force 63b is applied which, like the membrane force 62b, is directed upward.
- the membrane force 61b increases compared to the membrane force 61a in FIG. 5A, the membrane force 2 62b is now smaller than the membrane force 62a in FIG. 5A.
- the system in FIG. 5B is now deflected from the original zero position 60a, the current zero position 60b is shifted upwards. In this position 60b there is a balance of forces.
- FIG. 5C shows a downward deflection of the system. It is in the new zero position 60c when there is an external force 63c.
- the membrane force 1 61c is lower than in the reference case of FIG. 5A, the membrane force 2 62c is, however, greater than the force 62a in Fig. 5A.
- adapter membrane 7 and the pump membrane 24 are prestressed against each other in such a way that their inherent stiffness is approximately compensated, then in the event of the action of force e.g. A T-plunger 6 on the membrane system ensures that only little force or energy is lost to the system and is removed from the measurement by the sensor.
- FIG. 6 shows a diagram for the compensation of inherent stiffness of two membranes.
- a soft membrane was used for the pump membrane 24 and a comparatively harder membrane was used for the adapter membrane 7.
- the diagram in Fig. 6 shows the resulting forces when the system is deflected up and down from the zero point.
- the curve belonging to the pump membrane has a relatively small negative slope.
- the curve of the adapter membrane has a positive slope, which is significantly larger than the slope of the curve of the adapter membrane.
- the curve of the resultant is drawn and of great interest. It is the force that is required for the deflection according to the resultant that is lost by the measurement of the fluid pressure by the sensor.
- 7 shows a pump 70 according to the invention with an adapter 1 and a pump interface 18. The adapter 1 is placed on the pump interface 18.
- An ampoule 71 is inserted into the pump 70. A fluid is pressed out of this by means of a movable plug 72.
- the plug 72 is coupled to a threaded rod 73 which is moved by a motor 74.
- the fluid path of the fluid initially runs out of the ampoule 71 into a cannula 9 which is attached to the fluid channel 2 of the adapter 1.
- the cannula 9 pierces a septum 78, with the aid of which the ampoule 71 has been closed.
- the fluid path continues through the fluid channel 2 into a chamber 8.
- the chamber 8 has a relatively small filling volume so that a dead volume is kept as low as possible.
- connection option 76 for an infusion set
- this connection option 76 is formed by a Luer, other connections are also possible.
- the fluid channel 2 is in contact with an insert 5 on the underside.
- the insert 5 consists of a T-plunger 6 and an adapter membrane 7.
- the adapter membrane 7 serves for the elastic mounting of the T-plunger 6.
- the adapter membrane 7 is firmly clamped into the adapter 1 at the edges 80a.
- the plunger 6 is made of a rigid material, the adapter membrane 7 has low inherent rigidity and a U-shaped cross section.
- the adapter membrane 7 is formed in a ring-shaped manner around the T-plunger 6 and also fulfills a sealing function.
- the transmission piece 19 comprises a pump diaphragm 24 and a counter tappet 21.
- the counter tappet 21 is made of a rigid material and has a constriction 21a.
- the counter plunger 21 is dumbbell-shaped in this embodiment.
- the pump diaphragm 24 is in contact with the counter-plunger 21 in the constriction 21a.
- the pump membrane 24 is formed in a ring-shaped manner around the counter-plunger 21. It serves for the elastic mounting of the counter tappet and is fixed at the ends 80b in the pump interface.
- the pump membrane 24 has a low inherent rigidity and a U-shaped cross section.
- the transmission piece 19 or the counter-plunger 21 is in contact with a detector 20a for the detection of occlusions and / or leaks.
- two protective brackets are attached to the pump interface 18 as protection against contact 25.
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Abstract
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Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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EP04804322A EP1720589A1 (de) | 2004-03-05 | 2004-12-27 | Adapter und pumpeninterface zur druckmessung für eine infusionspumpe |
US11/469,532 US20070088265A1 (en) | 2004-03-05 | 2006-09-01 | Adapter and pump interface for measuring pressure on an infusion pump |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004010843.9 | 2004-03-05 | ||
DE102004010843A DE102004010843B4 (de) | 2004-03-05 | 2004-03-05 | Adapter und Pumpeninterface zur Druckmessung für eine Infusionspumpe |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/469,532 Continuation US20070088265A1 (en) | 2004-03-05 | 2006-09-01 | Adapter and pump interface for measuring pressure on an infusion pump |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005092412A1 true WO2005092412A1 (de) | 2005-10-06 |
Family
ID=34877438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2004/014732 WO2005092412A1 (de) | 2004-03-05 | 2004-12-27 | Adapter und pumpeninterface zur druckmessung für eine infusionspumpe |
Country Status (4)
Country | Link |
---|---|
US (1) | US20070088265A1 (de) |
EP (1) | EP1720589A1 (de) |
DE (1) | DE102004010843B4 (de) |
WO (1) | WO2005092412A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2967506B1 (de) * | 2013-03-15 | 2020-04-29 | Becton, Dickinson and Company | Intelligenter adapter für infusionsvorrichtungen |
DE102017121347A1 (de) * | 2017-09-14 | 2019-03-14 | Turck Holding Gmbh | Schlauchdrucksensor für eine Schlauchpumpenanordnung |
CN107702869B (zh) * | 2017-10-31 | 2019-03-15 | 宁波佗鹊堂生物科技有限公司 | 一次性使用静脉输液针用气检仪 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4226124A (en) * | 1979-04-02 | 1980-10-07 | Baxter Travenol Laboratories, Inc. | Pressure isolator |
US4364386A (en) * | 1980-12-08 | 1982-12-21 | Imed Corporation | Apparatus for converting a pump to a controller |
GB2227077A (en) * | 1988-11-26 | 1990-07-18 | Roy Flitcroft | Infusion apparatus |
US5235324A (en) * | 1990-07-23 | 1993-08-10 | Asulab S.A. | Detector for over-pressure inside a pipe and a pump fitted with such a detector |
WO1995032013A1 (en) * | 1994-05-23 | 1995-11-30 | Elan Medical Technologies Limited | Liquid delivery device |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4142524A (en) * | 1977-06-02 | 1979-03-06 | Andros Incorporated | Cassette for intravenous delivery system |
US4277227A (en) * | 1979-07-02 | 1981-07-07 | Imed Corporation | Apparatus for converting a pump to a controller |
US4303376A (en) * | 1979-07-09 | 1981-12-01 | Baxter Travenol Laboratories, Inc. | Flow metering cassette and controller |
JPS5631758A (en) * | 1979-08-24 | 1981-03-31 | Sharp Kk | Detector for clogging condition of flexible tube |
US4657490A (en) * | 1985-03-27 | 1987-04-14 | Quest Medical, Inc. | Infusion pump with disposable cassette |
IE960927A1 (en) * | 1996-12-31 | 1998-07-01 | Elan Med Tech | A device for generating a pulsatile fluid drug flow |
DE19900937A1 (de) * | 1999-01-13 | 2000-07-20 | Ulrich Gmbh & Co Kg | Injektor zur Applizierung von Flüssigkeiten mit einem Druckmeßsystem |
-
2004
- 2004-03-05 DE DE102004010843A patent/DE102004010843B4/de not_active Expired - Fee Related
- 2004-12-27 WO PCT/EP2004/014732 patent/WO2005092412A1/de not_active Application Discontinuation
- 2004-12-27 EP EP04804322A patent/EP1720589A1/de not_active Withdrawn
-
2006
- 2006-09-01 US US11/469,532 patent/US20070088265A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4226124A (en) * | 1979-04-02 | 1980-10-07 | Baxter Travenol Laboratories, Inc. | Pressure isolator |
US4364386A (en) * | 1980-12-08 | 1982-12-21 | Imed Corporation | Apparatus for converting a pump to a controller |
GB2227077A (en) * | 1988-11-26 | 1990-07-18 | Roy Flitcroft | Infusion apparatus |
US5235324A (en) * | 1990-07-23 | 1993-08-10 | Asulab S.A. | Detector for over-pressure inside a pipe and a pump fitted with such a detector |
WO1995032013A1 (en) * | 1994-05-23 | 1995-11-30 | Elan Medical Technologies Limited | Liquid delivery device |
Also Published As
Publication number | Publication date |
---|---|
EP1720589A1 (de) | 2006-11-15 |
DE102004010843A1 (de) | 2005-09-22 |
DE102004010843B4 (de) | 2009-01-29 |
US20070088265A1 (en) | 2007-04-19 |
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