WO2005089509A3 - Systemes d'essai a haut debit et procedes pour identifier des agents qui modifient l'expression de proteines cellulaires - Google Patents
Systemes d'essai a haut debit et procedes pour identifier des agents qui modifient l'expression de proteines cellulaires Download PDFInfo
- Publication number
- WO2005089509A3 WO2005089509A3 PCT/US2005/009298 US2005009298W WO2005089509A3 WO 2005089509 A3 WO2005089509 A3 WO 2005089509A3 US 2005009298 W US2005009298 W US 2005009298W WO 2005089509 A3 WO2005089509 A3 WO 2005089509A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- high throughput
- assay systems
- identifying agents
- throughput assay
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5061—Muscle cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/12—Condition responsive control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05733189A EP1735624A4 (fr) | 2004-03-19 | 2005-03-17 | Systemes d'essai a haut debit et procedes pour identifier des agents qui modifient l'expression de proteines cellulaires |
JP2007504174A JP5284637B2 (ja) | 2004-03-19 | 2005-03-17 | 細胞タンパク質の発現を変化させる薬剤を同定するためのハイスループットアッセイ系および方法 |
AU2005223851A AU2005223851A1 (en) | 2004-03-19 | 2005-03-17 | High throughput assay systems and methods for identifying agents that alter expression of cellular proteins |
CA002562474A CA2562474A1 (fr) | 2004-03-19 | 2005-03-17 | Systemes d'essai a haut debit et procedes pour identifier des agents qui modifient l'expression de proteines cellulaires |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/804,214 US20050208595A1 (en) | 2004-03-19 | 2004-03-19 | High throughput assay systems and methods for identifying agents that alter expression of cellular proteins |
US10/804,214 | 2004-03-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005089509A2 WO2005089509A2 (fr) | 2005-09-29 |
WO2005089509A3 true WO2005089509A3 (fr) | 2005-12-22 |
Family
ID=34986830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/009298 WO2005089509A2 (fr) | 2004-03-19 | 2005-03-17 | Systemes d'essai a haut debit et procedes pour identifier des agents qui modifient l'expression de proteines cellulaires |
Country Status (8)
Country | Link |
---|---|
US (2) | US20050208595A1 (fr) |
EP (1) | EP1735624A4 (fr) |
JP (1) | JP5284637B2 (fr) |
CN (1) | CN1973203A (fr) |
AU (1) | AU2005223851A1 (fr) |
CA (1) | CA2562474A1 (fr) |
NZ (1) | NZ595791A (fr) |
WO (1) | WO2005089509A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008066525A2 (fr) * | 2006-11-30 | 2008-06-05 | Dancu Michael B | Système et procédé pour produire des conditions dynamiques, y compris des conditions hémodynamiques in vivo, dans une structure tubulaire tridimensionnelle |
WO2009009718A1 (fr) | 2007-07-11 | 2009-01-15 | Sru Biosystems, Inc. | Procédés d'identification de modulateurs de canaux ioniques |
US9134307B2 (en) | 2007-07-11 | 2015-09-15 | X-Body, Inc. | Method for determining ion channel modulating properties of a test reagent |
AU2011305249B2 (en) | 2010-09-26 | 2015-07-23 | Da Yu Enterprises, L.L.C. | Method of recombinant macromolecular production |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020150912A1 (en) * | 2000-09-07 | 2002-10-17 | Owman Christer S. O. | Reporter system for cell surface receptor-ligand binding |
US6831154B1 (en) * | 2001-05-16 | 2004-12-14 | Myriad Genetics, Inc. | Membrane-associated protein 17KD (MAP17)-interacting protein and use thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1545094A (en) * | 1976-12-14 | 1979-05-02 | Gist Brocades Nv | Piperazine derivatives |
NL8202636A (nl) * | 1982-06-29 | 1984-01-16 | Gist Brocades Nv | Piperazinederivaten, werkwijzen ter bereiding daarvan en farmaceutische preparaten die deze verbindingen bevatten. |
HU196194B (en) | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds |
CA2064574A1 (fr) | 1989-08-03 | 1991-02-04 | Richard B. Rothman | Produit et traitement pour soigner l'intoxication a la ***e et empecher la recidive pendant et apres le traitement, grace a un antagoniste de la ***e, de l'amphetamine et dela phencyclidine |
SE510795C2 (sv) | 1996-10-29 | 1999-06-21 | Sca Packaging Display Ab | Skyddshuv med integrerat bildat exponeringsställ |
GB9705428D0 (en) * | 1997-03-15 | 1997-04-30 | Knoll Ag | Therapeutic agents |
AU5477500A (en) * | 1999-06-09 | 2000-12-28 | General Hospital Corporation, The | Method of measuring plasma membrane targeting of glut4 |
JP4754143B2 (ja) * | 1999-10-12 | 2011-08-24 | ケモセントリックス, インコーポレイテッド | ケモカインレセプター |
US7179462B2 (en) * | 2000-06-02 | 2007-02-20 | University Of Connecticut Health Center | α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
FR2812945B1 (fr) * | 2000-08-10 | 2002-10-04 | Aventis Pharma Sa | Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules |
US6846643B2 (en) * | 2000-08-14 | 2005-01-25 | Boehringer Ingelheim Pharmaceuticals, Inc. | Methods and molecules useful for identifying molecules that bind LFA-1 and for determining receptor occupancy |
WO2002036733A2 (fr) * | 2000-10-06 | 2002-05-10 | Antigenics Inc. | Cd36 en tant que recepteur de la proteine de choc thermique et ses utilisations |
AU2002230820A1 (en) * | 2000-12-18 | 2002-07-01 | Gene Logic, Inc. | Gene expression profiles associated with osteoblast differentiation |
JP2003024088A (ja) * | 2001-04-27 | 2003-01-28 | Takeda Chem Ind Ltd | 新規gタンパク質共役型レセプタータンパク質およびそのdna |
EP1258495A1 (fr) * | 2001-05-09 | 2002-11-20 | Millennium Pharmaceuticals, Inc. | 98359, Sous unité beta 4 du canal sodique, et ses applications |
US6929923B2 (en) * | 2002-07-23 | 2005-08-16 | Rigel Pharmaceuticals, Inc. | Modulators of leukocyte activation, BIC compositions and methods of use |
US8071321B2 (en) * | 2002-08-29 | 2011-12-06 | Cytocure Llc | Methods for up-regulating antigen expression in tumors |
US7211407B2 (en) * | 2003-07-15 | 2007-05-01 | Chan Test, Inc. | High throughput assay systems and methods for identifying agents that alter surface expression of integral membrane proteins |
-
2004
- 2004-03-19 US US10/804,214 patent/US20050208595A1/en not_active Abandoned
-
2005
- 2005-03-17 CN CNA2005800142798A patent/CN1973203A/zh active Pending
- 2005-03-17 EP EP05733189A patent/EP1735624A4/fr not_active Withdrawn
- 2005-03-17 WO PCT/US2005/009298 patent/WO2005089509A2/fr active Application Filing
- 2005-03-17 NZ NZ595791A patent/NZ595791A/xx not_active IP Right Cessation
- 2005-03-17 AU AU2005223851A patent/AU2005223851A1/en not_active Abandoned
- 2005-03-17 JP JP2007504174A patent/JP5284637B2/ja active Active
- 2005-03-17 CA CA002562474A patent/CA2562474A1/fr not_active Abandoned
-
2008
- 2008-07-08 US US12/216,579 patent/US7678548B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020150912A1 (en) * | 2000-09-07 | 2002-10-17 | Owman Christer S. O. | Reporter system for cell surface receptor-ligand binding |
US6831154B1 (en) * | 2001-05-16 | 2004-12-14 | Myriad Genetics, Inc. | Membrane-associated protein 17KD (MAP17)-interacting protein and use thereof |
Non-Patent Citations (1)
Title |
---|
See also references of EP1735624A4 * |
Also Published As
Publication number | Publication date |
---|---|
NZ595791A (en) | 2013-05-31 |
CA2562474A1 (fr) | 2005-09-29 |
CN1973203A (zh) | 2007-05-30 |
US20050208595A1 (en) | 2005-09-22 |
JP5284637B2 (ja) | 2013-09-11 |
WO2005089509A2 (fr) | 2005-09-29 |
EP1735624A2 (fr) | 2006-12-27 |
US7678548B2 (en) | 2010-03-16 |
EP1735624A4 (fr) | 2008-05-21 |
US20080268472A1 (en) | 2008-10-30 |
AU2005223851A1 (en) | 2005-09-29 |
JP2007529756A (ja) | 2007-10-25 |
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