WO2005083116A3 - Detection of nucleic acids - Google Patents

Detection of nucleic acids Download PDF

Info

Publication number
WO2005083116A3
WO2005083116A3 PCT/GB2005/000709 GB2005000709W WO2005083116A3 WO 2005083116 A3 WO2005083116 A3 WO 2005083116A3 GB 2005000709 W GB2005000709 W GB 2005000709W WO 2005083116 A3 WO2005083116 A3 WO 2005083116A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
nucleic acids
nucleic acid
resistivity
electrode
Prior art date
Application number
PCT/GB2005/000709
Other languages
French (fr)
Other versions
WO2005083116A2 (en
Inventor
Seamus Patrick John Higson
Frank Davis
Original Assignee
Univ Cranfield
Seamus Patrick John Higson
Frank Davis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cranfield, Seamus Patrick John Higson, Frank Davis filed Critical Univ Cranfield
Priority to GB0616288A priority Critical patent/GB2427470A/en
Publication of WO2005083116A2 publication Critical patent/WO2005083116A2/en
Publication of WO2005083116A3 publication Critical patent/WO2005083116A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Abstract

A single stranded nucleic acid is deposited on an electrode whose resistivity or impedance is monitored. When the electrode is placed in a solution containing complementary nucleic acid, its resistivity and impedance change.
PCT/GB2005/000709 2004-02-25 2005-02-25 Detection of nucleic acids WO2005083116A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0616288A GB2427470A (en) 2004-02-25 2005-02-25 Detection of nucleic acids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0404135.6 2004-02-25
GB0404135A GB0404135D0 (en) 2004-02-25 2004-02-25 Impedimetric DNA hybridisation sensor

Publications (2)

Publication Number Publication Date
WO2005083116A2 WO2005083116A2 (en) 2005-09-09
WO2005083116A3 true WO2005083116A3 (en) 2006-02-23

Family

ID=32050812

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/000709 WO2005083116A2 (en) 2004-02-25 2005-02-25 Detection of nucleic acids

Country Status (2)

Country Link
GB (2) GB0404135D0 (en)
WO (1) WO2005083116A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096825A (en) * 1994-04-22 2000-08-01 Bio Merieux Electrically conductive electroactive functionalized conjugated polymers, and uses thereof
US6468785B1 (en) * 1999-02-19 2002-10-22 New Mexico State University Technology Transfer Corporation Doped conducting polymers applications and methods
DE10214719A1 (en) * 2002-04-03 2003-11-20 Infineon Technologies Ag Sensor for the qualitative and quantitative determination of (bio) organic oligomers and polymers, analysis methods for this as well as methods for producing the sensor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096825A (en) * 1994-04-22 2000-08-01 Bio Merieux Electrically conductive electroactive functionalized conjugated polymers, and uses thereof
US6468785B1 (en) * 1999-02-19 2002-10-22 New Mexico State University Technology Transfer Corporation Doped conducting polymers applications and methods
DE10214719A1 (en) * 2002-04-03 2003-11-20 Infineon Technologies Ag Sensor for the qualitative and quantitative determination of (bio) organic oligomers and polymers, analysis methods for this as well as methods for producing the sensor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
YONG SHAO ET AL: "DNA-templated assembly and electropolymerization of aniline on gold surface", ELECTROCHEMISTRY COMMUNICATIONS ELSEVIER SWITZERLAND, vol. 4, no. 10, October 2002 (2002-10-01), pages 773 - 779, XP002349800, ISSN: 1388-2481 *

Also Published As

Publication number Publication date
GB2427470A (en) 2006-12-27
GB0616288D0 (en) 2006-09-27
WO2005083116A2 (en) 2005-09-09
GB0404135D0 (en) 2004-03-31

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