WO2005080565A8 - Dnaメチル化分析用dnaアレイ及びその製造方法並びにdnaメチル化分析方法 - Google Patents
Dnaメチル化分析用dnaアレイ及びその製造方法並びにdnaメチル化分析方法Info
- Publication number
- WO2005080565A8 WO2005080565A8 PCT/JP2005/002490 JP2005002490W WO2005080565A8 WO 2005080565 A8 WO2005080565 A8 WO 2005080565A8 JP 2005002490 W JP2005002490 W JP 2005002490W WO 2005080565 A8 WO2005080565 A8 WO 2005080565A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dna
- dna fragments
- analyzing
- constructing
- cytosine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00675—In-situ synthesis on the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Nanotechnology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Structural Engineering (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/590,122 US20080227652A1 (en) | 2004-02-20 | 2005-02-17 | Dna Array for Analyzing Dna Methylation, Method of Producing the Same and Method of Analyzing Dna Methylation |
EP05710340A EP1717312B1 (en) | 2004-02-20 | 2005-02-17 | Dna array for analyzing dna methylation, method of constructing the same and mehtod of analyzing dna methylaion |
DE602005023710T DE602005023710D1 (de) | 2004-02-20 | 2005-02-17 | Dna-array zur analyse der dna-methylierung, konstruktionsverfahren dafür sowie verfahren zur analyse der dna-methylierung |
JP2006510228A JP4688792B2 (ja) | 2004-02-20 | 2005-02-17 | Dnaメチル化分析用dnaアレイ及びその製造方法並びにdnaメチル化分析方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004044759 | 2004-02-20 | ||
JP2004-044759 | 2004-02-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005080565A1 WO2005080565A1 (ja) | 2005-09-01 |
WO2005080565A8 true WO2005080565A8 (ja) | 2006-01-26 |
Family
ID=34879358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2005/002490 WO2005080565A1 (ja) | 2004-02-20 | 2005-02-17 | Dnaメチル化分析用dnaアレイ及びその製造方法並びにdnaメチル化分析方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20080227652A1 (ja) |
EP (1) | EP1717312B1 (ja) |
JP (1) | JP4688792B2 (ja) |
DE (1) | DE602005023710D1 (ja) |
WO (1) | WO2005080565A1 (ja) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0413688D0 (en) * | 2004-06-18 | 2004-07-21 | Novartis Forschungsstiftung | Analysis of methylated nucleic acid |
AU2005308916B2 (en) * | 2004-11-29 | 2011-07-21 | Sequenom, Inc. | Kits and methods for detecting methylated DNA |
US7794939B2 (en) * | 2007-02-26 | 2010-09-14 | University Of Idaho | Methods of DNA methylation detection |
JP5211790B2 (ja) * | 2007-03-26 | 2013-06-12 | 住友化学株式会社 | Dnaメチル化測定方法 |
WO2009131223A1 (ja) * | 2008-04-25 | 2009-10-29 | 地方独立行政法人東京都健康長寿医療センター | Dnaメチル化分析方法 |
JP2010017178A (ja) * | 2008-06-11 | 2010-01-28 | Sumitomo Chemical Co Ltd | Dnaを定量又は検出する方法 |
JP2010017179A (ja) * | 2008-06-11 | 2010-01-28 | Sumitomo Chemical Co Ltd | Dnaを定量又は検出する方法 |
EP2443459B1 (en) * | 2009-06-19 | 2018-12-26 | The Arizona Board of Regents, A Body Corporate Of the State of Arizona acting for and on behalf Of Arizona State University | Compound arrays for sample profiling |
JP6095058B2 (ja) | 2013-03-14 | 2017-03-15 | 国立研究開発法人産業技術総合研究所 | メチルシトシン検出法 |
US20200399678A1 (en) * | 2017-10-30 | 2020-12-24 | Naomi Yamakawa | Method for analyzing dna methylation using next generation sequencer and method for concentrating specific dna fragments |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0322981A (ja) * | 1989-06-21 | 1991-01-31 | Akita Pref Gov | poly(A)と反応するモノクローン抗体を用いたpoly(A)↑+mRNAの精製法 |
US6506594B1 (en) * | 1999-03-19 | 2003-01-14 | Cornell Res Foundation Inc | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
US6610489B2 (en) * | 2000-04-28 | 2003-08-26 | Sangamo Biosciences, Inc. | Pharmacogenomics and identification of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions |
US6649347B2 (en) * | 2000-06-23 | 2003-11-18 | Chromatin, Inc. | Use of methylated nucleic acid segments for isolating centromere DNA |
AUPR142500A0 (en) * | 2000-11-13 | 2000-12-07 | Human Genetic Signatures Pty Ltd | A peptide nucleic acid-based assay for the detection of specific nucleic acid sequences |
WO2002086169A1 (en) * | 2001-04-23 | 2002-10-31 | Dana-Farber Cancer Institute, Inc. | Methods for rapid screening of polymorphisms, mutations and methylation |
JP2003038183A (ja) * | 2001-06-22 | 2003-02-12 | Dna Chip Kenkyusho:Kk | ゲノムdna中のメチレーションサイトのメチル化検出用バイオチップ及びメチル化検出方法 |
CA2489360C (en) * | 2002-06-26 | 2013-01-29 | Cold Spring Harbor Laboratory | Methods and compositions for determining methylation profiles |
WO2004059007A2 (en) * | 2002-12-25 | 2004-07-15 | National Institute Of Advanced Industrial Science And Technology | Nucleic acid methylation detection process using an internal reference sample |
JP3854943B2 (ja) * | 2003-05-23 | 2006-12-06 | 独立行政法人科学技術振興機構 | Dnaメチル化率の測定方法 |
-
2005
- 2005-02-17 US US10/590,122 patent/US20080227652A1/en not_active Abandoned
- 2005-02-17 DE DE602005023710T patent/DE602005023710D1/de active Active
- 2005-02-17 WO PCT/JP2005/002490 patent/WO2005080565A1/ja active Application Filing
- 2005-02-17 EP EP05710340A patent/EP1717312B1/en not_active Not-in-force
- 2005-02-17 JP JP2006510228A patent/JP4688792B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE602005023710D1 (de) | 2010-11-04 |
EP1717312B1 (en) | 2010-09-22 |
EP1717312A1 (en) | 2006-11-02 |
US20080227652A1 (en) | 2008-09-18 |
WO2005080565A1 (ja) | 2005-09-01 |
JP4688792B2 (ja) | 2011-05-25 |
JPWO2005080565A1 (ja) | 2007-10-25 |
EP1717312A4 (en) | 2008-05-14 |
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