WO2004083819A3 - Molecular forensic specimen marker - Google Patents

Molecular forensic specimen marker Download PDF

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Publication number
WO2004083819A3
WO2004083819A3 PCT/US2004/008332 US2004008332W WO2004083819A3 WO 2004083819 A3 WO2004083819 A3 WO 2004083819A3 US 2004008332 W US2004008332 W US 2004008332W WO 2004083819 A3 WO2004083819 A3 WO 2004083819A3
Authority
WO
WIPO (PCT)
Prior art keywords
identification marker
molecular identification
molecular
biological samples
segment
Prior art date
Application number
PCT/US2004/008332
Other languages
French (fr)
Other versions
WO2004083819A2 (en
Inventor
Jason Eshleman
Ripan Malhi
Original Assignee
Trace Genetics Inc
Jason Eshleman
Ripan Malhi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trace Genetics Inc, Jason Eshleman, Ripan Malhi filed Critical Trace Genetics Inc
Publication of WO2004083819A2 publication Critical patent/WO2004083819A2/en
Publication of WO2004083819A3 publication Critical patent/WO2004083819A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics

Abstract

A molecular identification marker for biological samples taken, for example, at a crime scene to confirm the chain of custody and identity of the biological samples at the time of analysis in a laboratory and method of use. The molecular identification marker also acts as an indicator of cross-contamination between marked samples or between reference and unknown biological samples. One embodiment of the molecular identification marker is a segment of DNA with at least one mutagenic primer site configured to produce a unique variant after mutagenic PCR, a segment configured to amplify for a selected forensic locus; and a segment configured for use with a probe to quantify the molecular identification marker.
PCT/US2004/008332 2003-03-17 2004-03-17 Molecular forensic specimen marker WO2004083819A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45550303P 2003-03-17 2003-03-17
US60/455,503 2003-03-17

Publications (2)

Publication Number Publication Date
WO2004083819A2 WO2004083819A2 (en) 2004-09-30
WO2004083819A3 true WO2004083819A3 (en) 2005-08-11

Family

ID=33030011

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/008332 WO2004083819A2 (en) 2003-03-17 2004-03-17 Molecular forensic specimen marker

Country Status (1)

Country Link
WO (1) WO2004083819A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1842926B1 (en) * 2006-03-10 2015-08-19 Epigenomics AG A method of identifying a biological sample for methylation analysis
EP2425240A4 (en) 2009-04-30 2012-12-12 Good Start Genetics Inc Methods and compositions for evaluating genetic markers
US9163281B2 (en) 2010-12-23 2015-10-20 Good Start Genetics, Inc. Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
US20120252686A1 (en) * 2011-03-31 2012-10-04 Good Start Genetics Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
US9228233B2 (en) 2011-10-17 2016-01-05 Good Start Genetics, Inc. Analysis methods
US8209130B1 (en) 2012-04-04 2012-06-26 Good Start Genetics, Inc. Sequence assembly
US8812422B2 (en) 2012-04-09 2014-08-19 Good Start Genetics, Inc. Variant database
US10227635B2 (en) 2012-04-16 2019-03-12 Molecular Loop Biosolutions, Llc Capture reactions
EP2971159B1 (en) 2013-03-14 2019-05-08 Molecular Loop Biosolutions, LLC Methods for analyzing nucleic acids
EP3005200A2 (en) 2013-06-03 2016-04-13 Good Start Genetics, Inc. Methods and systems for storing sequence read data
US11041203B2 (en) 2013-10-18 2021-06-22 Molecular Loop Biosolutions, Inc. Methods for assessing a genomic region of a subject
US10851414B2 (en) 2013-10-18 2020-12-01 Good Start Genetics, Inc. Methods for determining carrier status
WO2015175530A1 (en) 2014-05-12 2015-11-19 Gore Athurva Methods for detecting aneuploidy
WO2016040446A1 (en) 2014-09-10 2016-03-17 Good Start Genetics, Inc. Methods for selectively suppressing non-target sequences
CA2999708A1 (en) 2014-09-24 2016-03-31 Good Start Genetics, Inc. Process control for increased robustness of genetic assays
US10066259B2 (en) 2015-01-06 2018-09-04 Good Start Genetics, Inc. Screening for structural variants
EP3797163A4 (en) 2018-05-21 2022-03-09 Battelle Memorial Institute Methods and control compositions for sequencing and chemical analyses
WO2020124003A1 (en) * 2018-12-13 2020-06-18 Battelle Memorial Institute Methods and control compositions for a quantitative polymerase chain reaction
CN112466405B (en) * 2020-12-23 2021-06-22 阅尔基因技术（苏州）有限公司 Method for preparing molecular tag library for sequencing

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855909A (en) * 1987-11-20 1989-08-08 Hewlett-Packard Company Forensic sample tracking system and print station therefor
US5310653A (en) * 1989-10-24 1994-05-10 Board Of Regents, The University Of Texas System Tumor marker protein and antibodies thereto for cancer risk assessment or diagnosis
WO1998014275A1 (en) * 1996-10-04 1998-04-09 Intronn Llc Sample collection devices and methods using markers and the use of such markers as controls in sample validation, laboratory evaluation and/or accreditation
US6153389A (en) * 1999-02-22 2000-11-28 Haarer; Brian K. DNA additives as a mechanism for unambiguously marking biological samples
US20020136665A1 (en) * 2001-02-21 2002-09-26 Hayton Anthony John Swab assembly
US20030129738A1 (en) * 2002-01-04 2003-07-10 Sorenson James Levoy System, apparatus, composition and method for non-invasive extraction, secure handling and storage and facile processing and facile processing of a specimen

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855909A (en) * 1987-11-20 1989-08-08 Hewlett-Packard Company Forensic sample tracking system and print station therefor
US5310653A (en) * 1989-10-24 1994-05-10 Board Of Regents, The University Of Texas System Tumor marker protein and antibodies thereto for cancer risk assessment or diagnosis
WO1998014275A1 (en) * 1996-10-04 1998-04-09 Intronn Llc Sample collection devices and methods using markers and the use of such markers as controls in sample validation, laboratory evaluation and/or accreditation
US6153389A (en) * 1999-02-22 2000-11-28 Haarer; Brian K. DNA additives as a mechanism for unambiguously marking biological samples
US20020136665A1 (en) * 2001-02-21 2002-09-26 Hayton Anthony John Swab assembly
US20030129738A1 (en) * 2002-01-04 2003-07-10 Sorenson James Levoy System, apparatus, composition and method for non-invasive extraction, secure handling and storage and facile processing and facile processing of a specimen

Also Published As

Publication number Publication date
WO2004083819A2 (en) 2004-09-30

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