WO2004078112A3 - Apoptosis inducing gene - Google Patents

Apoptosis inducing gene Download PDF

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Publication number
WO2004078112A3
WO2004078112A3 PCT/JP2004/002899 JP2004002899W WO2004078112A3 WO 2004078112 A3 WO2004078112 A3 WO 2004078112A3 JP 2004002899 W JP2004002899 W JP 2004002899W WO 2004078112 A3 WO2004078112 A3 WO 2004078112A3
Authority
WO
WIPO (PCT)
Prior art keywords
apoptosis
dna
protein
recombinant vector
apoptosis inducing
Prior art date
Application number
PCT/JP2004/002899
Other languages
French (fr)
Other versions
WO2004078112A2 (en
Inventor
Shuji Muramatsu
Masahiro Takeda
Akio Matsuda
Original Assignee
Asahi Kasei Pharma Corp
Shuji Muramatsu
Masahiro Takeda
Akio Matsuda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Pharma Corp, Shuji Muramatsu, Masahiro Takeda, Akio Matsuda filed Critical Asahi Kasei Pharma Corp
Publication of WO2004078112A2 publication Critical patent/WO2004078112A2/en
Publication of WO2004078112A3 publication Critical patent/WO2004078112A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Proteins which is involved in apoptosis, which are used for diagnosing, treating or preventing diseases associated with disorder of apoptosis, are provided. cDNAs encoding proteins having an activity of inducing apoptosis were cloned from the cDNA library constructed from Jurkat cell, ATDC5 cell and the like, and the DNA sequence and the deduced amino acid sequence were determined. The protein, the DNA encoding the protein, a recombinant vector containing the DNA, and a transformat containing the recombinant vector are used for screening a substance which inhibits or induces apoptosis.
PCT/JP2004/002899 2003-03-07 2004-03-05 Apoptosis inducing gene WO2004078112A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2003061179 2003-03-07
JP2003-061179 2003-03-07
US45294303P 2003-03-10 2003-03-10
US60/452,943 2003-03-10

Publications (2)

Publication Number Publication Date
WO2004078112A2 WO2004078112A2 (en) 2004-09-16
WO2004078112A3 true WO2004078112A3 (en) 2005-02-10

Family

ID=32964912

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/002899 WO2004078112A2 (en) 2003-03-07 2004-03-05 Apoptosis inducing gene

Country Status (1)

Country Link
WO (1) WO2004078112A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006072951A2 (en) * 2005-01-06 2006-07-13 Yeda Research And Development Co. Ltd. Compositions and methods for regulating apoptosis
ES2319477B1 (en) * 2005-11-18 2010-02-16 Universidad De Zaragoza PSAP ISOFORMS, ANTIGENIC DETERMINANTS, METHOD OF OBTAINING ANTIBODIES AND USES OF THE SAME.
PL2288715T3 (en) 2008-04-11 2015-03-31 Merrimack Pharmaceuticals Inc Human serum albumin linkers and conjugates thereof
US11096901B2 (en) 2009-03-06 2021-08-24 Metaqor Llc Dynamic bio-nanoparticle platforms
US11235062B2 (en) * 2009-03-06 2022-02-01 Metaqor Llc Dynamic bio-nanoparticle elements
CN114533902A (en) * 2022-02-28 2022-05-27 河南师范大学 Plasmid vector for over-expressing LRRC15 gene and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078954A2 (en) * 1999-06-18 2000-12-28 Incyte Genomics, Inc. Human transcriptional regulator proteins
WO2002053737A1 (en) * 2000-12-28 2002-07-11 Asahi Kasei Kabushiki Kaisha Nf-kb activating gene

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000078954A2 (en) * 1999-06-18 2000-12-28 Incyte Genomics, Inc. Human transcriptional regulator proteins
WO2002053737A1 (en) * 2000-12-28 2002-07-11 Asahi Kasei Kabushiki Kaisha Nf-kb activating gene
EP1354950A1 (en) * 2000-12-28 2003-10-22 Asahi Kasei Kabushiki Kaisha Nf-kb activating gene

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ADAMS J M ET AL: "Life-or-death decisions by the Bcl-2 protein family.", TRENDS IN BIOCHEMICAL SCIENCES. JAN 2001, vol. 26, no. 1, January 2001 (2001-01-01), pages 61 - 66, XP002283498, ISSN: 0968-0004 *
DATABASE EMBL 13 December 2002 (2002-12-13), AKIRA S AND YAMAMOTO M: "Homo sapiens TRIF mRNA for TIR domain containing adaptor inducing interferon-beta, complete cds.", XP002283499, Database accession no. AB093555 *
DATABASE EMBL 21 January 2003 (2003-01-21), OSHIUMI H ET AL: "Homo sapiens mRNA for TICAM-1, complete cds.", XP002283500, Database accession no. AB086380 *
STRASSER A ET AL: "Apoptosis signaling.", ANNUAL REVIEW OF BIOCHEMISTRY. 2000, vol. 69, 2000, pages 217 - 245, XP002283497, ISSN: 0066-4154 *
YAMAMOTO MASAHIRO ET AL: "Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 169, no. 12, 15 December 2002 (2002-12-15), pages 6668 - 6672, XP002269637, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
WO2004078112A2 (en) 2004-09-16

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