WO2004076406A3 - Losartan potassium polymorphs and process for the preparation thereof - Google Patents

Losartan potassium polymorphs and process for the preparation thereof Download PDF

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Publication number
WO2004076406A3
WO2004076406A3 PCT/EP2004/001717 EP2004001717W WO2004076406A3 WO 2004076406 A3 WO2004076406 A3 WO 2004076406A3 EP 2004001717 W EP2004001717 W EP 2004001717W WO 2004076406 A3 WO2004076406 A3 WO 2004076406A3
Authority
WO
WIPO (PCT)
Prior art keywords
losartan potassium
polymorphs
preparation
losartan
potassium
Prior art date
Application number
PCT/EP2004/001717
Other languages
French (fr)
Other versions
WO2004076406A2 (en
Inventor
Andrea Boccignone
Luciana Malpezzi
Graziano Castaldi
Pietro Allegrini
Andrea Beltrame
Original Assignee
Dipharma Spa
Andrea Boccignone
Luciana Malpezzi
Graziano Castaldi
Pietro Allegrini
Andrea Beltrame
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Spa, Andrea Boccignone, Luciana Malpezzi, Graziano Castaldi, Pietro Allegrini, Andrea Beltrame filed Critical Dipharma Spa
Publication of WO2004076406A2 publication Critical patent/WO2004076406A2/en
Publication of WO2004076406A3 publication Critical patent/WO2004076406A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Losartan potassium polymorphs, identified as Losartan potassium crystalline hydrate, Losartan potassium amorphous and Losartan potassium modification crystalline III, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.
PCT/EP2004/001717 2003-02-25 2004-02-20 Losartan potassium polymorphs and process for the preparation thereof WO2004076406A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2003A000328 2003-02-25
IT000328A ITMI20030328A1 (en) 2003-02-25 2003-02-25 POLYMORPHS OF LOSARTAN POTASSIUM AND PROCEDURE FOR THEIR PREPARATION.

Publications (2)

Publication Number Publication Date
WO2004076406A2 WO2004076406A2 (en) 2004-09-10
WO2004076406A3 true WO2004076406A3 (en) 2005-01-13

Family

ID=32923033

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/001717 WO2004076406A2 (en) 2003-02-25 2004-02-20 Losartan potassium polymorphs and process for the preparation thereof

Country Status (2)

Country Link
IT (1) ITMI20030328A1 (en)
WO (1) WO2004076406A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060160871A1 (en) * 2004-12-07 2006-07-20 Nektar Therapeutics Stable non-crystalline formulation comprising losartan

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
US5608075A (en) * 1993-12-23 1997-03-04 Merck & Co., Inc. Polymorphs of losartan and the process for the preparation of form II of losartan
WO2002094816A1 (en) * 2001-05-18 2002-11-28 Aurobindo Pharma Limited Process for the crystallization of losartan potassium
WO2003048135A1 (en) * 2001-11-14 2003-06-12 Teva Pharmaceutical Industries Ltd. Amorphous and crystalline forms of losartan potassium and process for their preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
US5608075A (en) * 1993-12-23 1997-03-04 Merck & Co., Inc. Polymorphs of losartan and the process for the preparation of form II of losartan
WO2002094816A1 (en) * 2001-05-18 2002-11-28 Aurobindo Pharma Limited Process for the crystallization of losartan potassium
WO2003048135A1 (en) * 2001-11-14 2003-06-12 Teva Pharmaceutical Industries Ltd. Amorphous and crystalline forms of losartan potassium and process for their preparation

Also Published As

Publication number Publication date
ITMI20030328A1 (en) 2004-08-26
WO2004076406A2 (en) 2004-09-10

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