WO2004064971A3 - Process for preparing microcapsules having an improved mechanical resistance - Google Patents

Process for preparing microcapsules having an improved mechanical resistance Download PDF

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Publication number
WO2004064971A3
WO2004064971A3 PCT/CH2004/000029 CH2004000029W WO2004064971A3 WO 2004064971 A3 WO2004064971 A3 WO 2004064971A3 CH 2004000029 W CH2004000029 W CH 2004000029W WO 2004064971 A3 WO2004064971 A3 WO 2004064971A3
Authority
WO
WIPO (PCT)
Prior art keywords
microcapsules
mechanical resistance
improved mechanical
polymer membrane
core
Prior art date
Application number
PCT/CH2004/000029
Other languages
French (fr)
Other versions
WO2004064971A2 (en
Inventor
Anne Peters
Ian Marison
David Serp
Original Assignee
Inotech Ag
Anne Peters
Ian Marison
David Serp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inotech Ag, Anne Peters, Ian Marison, David Serp filed Critical Inotech Ag
Publication of WO2004064971A2 publication Critical patent/WO2004064971A2/en
Publication of WO2004064971A3 publication Critical patent/WO2004064971A3/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

A process for preparing microcapsules having an improved mechanical resistance, more specifically monodisperse microcapsules consisting of an organic liquid core surrounded by a hydrogel polymer membrane comprises: a) using selected hydrophobic organic liquid material as core constituent; b) using selected acrylamide and/or acrylamide derivatives together with alginate as constituents of the monomer mixture leading to the surrounding polymer membrane; c) initiating and then performing polymerization of the selected monomers up to the desired cross-linkage level of the polymer membrane; and d) subjecting the core and the membrane components to a suitable microcapsulation technology, whereby the microcapsules thus achieved have an improved mechanical resistance. Such microcapsules are useful e.g. as vectors for active compounds or as extraction means.
PCT/CH2004/000029 2003-01-23 2004-01-20 Process for preparing microcapsules having an improved mechanical resistance WO2004064971A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH0300050 2003-01-23
CHPCT/CH03/00050 2003-01-23

Publications (2)

Publication Number Publication Date
WO2004064971A2 WO2004064971A2 (en) 2004-08-05
WO2004064971A3 true WO2004064971A3 (en) 2004-10-14

Family

ID=32739293

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2004/000029 WO2004064971A2 (en) 2003-01-23 2004-01-20 Process for preparing microcapsules having an improved mechanical resistance

Country Status (1)

Country Link
WO (1) WO2004064971A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2964017B1 (en) * 2010-09-01 2013-05-31 Capsum PROCESS FOR MANUFACTURING A SERIES OF SUBMILLIMETER SIZE CAPSULES
CN103041445A (en) * 2013-01-21 2013-04-17 天津工业大学 Method for preparing molecular imprinting porous gel membrane for tissue engineering
CN103013976A (en) * 2013-01-21 2013-04-03 天津工业大学 Method for preparing organic-inorganic composite hydrogel membrane and grafting material containing immobilized biological macromolecules
CN104177540B (en) * 2014-03-19 2016-05-18 太原理工大学 The preparation method of the fluorescent type temperature intelligent response sensor based on gold nanoclusters
US20210002433A1 (en) * 2018-03-02 2021-01-07 Sigilon Therapeutics, Inc. Biocompatible hydrogel capsules and process for preparing same
US11794161B1 (en) 2018-11-21 2023-10-24 Trucapsol, Llc Reduced permeability microcapsules
US11571674B1 (en) 2019-03-28 2023-02-07 Trucapsol Llc Environmentally biodegradable microcapsules
US11542392B1 (en) 2019-04-18 2023-01-03 Trucapsol Llc Multifunctional particle additive for enhancement of toughness and degradation in biodegradable polymers
US11465117B2 (en) 2020-01-30 2022-10-11 Trucapsol Llc Environmentally biodegradable microcapsules
US11878280B2 (en) 2022-04-19 2024-01-23 Trucapsol Llc Microcapsules comprising natural materials
US11904288B1 (en) 2023-02-13 2024-02-20 Trucapsol Llc Environmentally biodegradable microcapsules
US11969491B1 (en) 2023-02-22 2024-04-30 Trucapsol Llc pH triggered release particle

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2599639A1 (en) * 1986-06-06 1987-12-11 Univ Ramot Process and apparatus for the manufacture of polymer pearls
JPH0780282A (en) * 1993-06-24 1995-03-28 Ebara Res Co Ltd Polymeric hydrogel granular material, production thereof and immobilization of bacteria using the same
DE10022447A1 (en) * 1999-05-28 2001-03-08 Inotech Ag Dottikon In situ extraction of products from fermentations, particularly products that inhibit growth, using encapsulated organic solvent
EP1306128A1 (en) * 2001-10-29 2003-05-02 Tenaxis Gmbh Sorptive composite materials

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2599639A1 (en) * 1986-06-06 1987-12-11 Univ Ramot Process and apparatus for the manufacture of polymer pearls
JPH0780282A (en) * 1993-06-24 1995-03-28 Ebara Res Co Ltd Polymeric hydrogel granular material, production thereof and immobilization of bacteria using the same
DE10022447A1 (en) * 1999-05-28 2001-03-08 Inotech Ag Dottikon In situ extraction of products from fermentations, particularly products that inhibit growth, using encapsulated organic solvent
EP1306128A1 (en) * 2001-10-29 2003-05-02 Tenaxis Gmbh Sorptive composite materials

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 1995, no. 06 31 July 1995 (1995-07-31) *
STARK, D. ET AL.: "Novel type of in situ extraction: use of solvent containing microcapsules for the bioconversion of 2-Phenylethanol from L-Phenylalanine by Saccharomyces cerevisiae", BIOTECHNOLOGY AND BIOENGINEERING, vol. 83, no. 4, 20 August 2003 (2003-08-20), pages 376 - 385, XP002293121 *

Also Published As

Publication number Publication date
WO2004064971A2 (en) 2004-08-05

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