WO2004052928A3 - Midkine-like protein - Google Patents

Midkine-like protein Download PDF

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Publication number
WO2004052928A3
WO2004052928A3 PCT/GB2003/005374 GB0305374W WO2004052928A3 WO 2004052928 A3 WO2004052928 A3 WO 2004052928A3 GB 0305374 W GB0305374 W GB 0305374W WO 2004052928 A3 WO2004052928 A3 WO 2004052928A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
midkine
insp106
lowbar
swall
Prior art date
Application number
PCT/GB2003/005374
Other languages
French (fr)
Other versions
WO2004052928A2 (en
Inventor
Carmit Levita
Richard Joseph Fagan
David Michalovich
Melanie Yorke
Original Assignee
Ares Trading Sa
Carmit Levita
Richard Joseph Fagan
David Michalovich
Melanie Yorke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa, Carmit Levita, Richard Joseph Fagan, David Michalovich, Melanie Yorke filed Critical Ares Trading Sa
Priority to JP2004558824A priority Critical patent/JP2006525783A/en
Priority to EP03786100A priority patent/EP1572737A2/en
Priority to AU2003295100A priority patent/AU2003295100A1/en
Priority to CA002507554A priority patent/CA2507554A1/en
Priority to US10/538,195 priority patent/US20060216709A1/en
Publication of WO2004052928A2 publication Critical patent/WO2004052928A2/en
Publication of WO2004052928A3 publication Critical patent/WO2004052928A3/en
Priority to NO20052608A priority patent/NO20052608L/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
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Abstract

The invention is based on the discovery that the INSP106 protein is a novel splice variant of a known midkine family member (swall|P21741|MK_HUMAN).
PCT/GB2003/005374 2002-12-10 2003-12-10 Midkine-like protein WO2004052928A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2004558824A JP2006525783A (en) 2002-12-10 2003-12-10 Midkine-like protein
EP03786100A EP1572737A2 (en) 2002-12-10 2003-12-10 Midkine-like protein
AU2003295100A AU2003295100A1 (en) 2002-12-10 2003-12-10 Midkine-like protein
CA002507554A CA2507554A1 (en) 2002-12-10 2003-12-10 Midkine-like protein
US10/538,195 US20060216709A1 (en) 2003-12-10 2003-12-10 Midkine-like protein
NO20052608A NO20052608L (en) 2002-12-10 2005-05-31 Midkin-like protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0228776.1A GB0228776D0 (en) 2002-12-10 2002-12-10 Splice variant
GB0228776.1 2002-12-10

Publications (2)

Publication Number Publication Date
WO2004052928A2 WO2004052928A2 (en) 2004-06-24
WO2004052928A3 true WO2004052928A3 (en) 2004-08-05

Family

ID=9949416

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/005374 WO2004052928A2 (en) 2002-12-10 2003-12-10 Midkine-like protein

Country Status (7)

Country Link
EP (1) EP1572737A2 (en)
JP (1) JP2006525783A (en)
AU (1) AU2003295100A1 (en)
CA (1) CA2507554A1 (en)
GB (1) GB0228776D0 (en)
NO (1) NO20052608L (en)
WO (1) WO2004052928A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011115562A1 (en) * 2010-03-18 2011-09-22 Egesten Medical Consulting Hb Antimicrobial compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0476233A1 (en) * 1990-08-20 1992-03-25 American Cyanamid Company Human MK gene and protein sequence
US6083907A (en) * 1995-10-02 2000-07-04 Meiji Milk Products Co., Ltd. Treatment of peptic ulcers using midkine (MK) proteins
WO2001036635A2 (en) * 1999-11-15 2001-05-25 Curagen Corporation Neurite outgrowth-promoting factor homologue and nucleic acids encoding same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0476233A1 (en) * 1990-08-20 1992-03-25 American Cyanamid Company Human MK gene and protein sequence
US6083907A (en) * 1995-10-02 2000-07-04 Meiji Milk Products Co., Ltd. Treatment of peptic ulcers using midkine (MK) proteins
WO2001036635A2 (en) * 1999-11-15 2001-05-25 Curagen Corporation Neurite outgrowth-promoting factor homologue and nucleic acids encoding same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AKHTER SHAMIMA ET AL: "Clusters of basic amino acids in midkine: Roles in neurite-promoting activity and plasminogen activator-enhancing activity", JOURNAL OF BIOCHEMISTRY (TOKYO), vol. 123, no. 6, June 1998 (1998-06-01), pages 1127 - 1136, XP001189525, ISSN: 0021-924X *
BERNARD-PIERROT ISABELLE ET AL: "Dominant negative effectors of heparin affin regulatory peptide (HARP) angiogenic and transforming activities", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 277, no. 35, 30 August 2002 (2002-08-30), pages 32071 - 32077, XP002245580, ISSN: 0021-9258 *
DATABASE UNIPROT [online] 1 October 2000 (2000-10-01), IKEDA,S. ET AL.: "Midkine precursor", XP002282467, Database accession no. Q9N0E6 *

Also Published As

Publication number Publication date
NO20052608D0 (en) 2005-05-31
JP2006525783A (en) 2006-11-16
GB0228776D0 (en) 2003-01-15
AU2003295100A1 (en) 2004-06-30
EP1572737A2 (en) 2005-09-14
CA2507554A1 (en) 2004-06-24
WO2004052928A2 (en) 2004-06-24
NO20052608L (en) 2005-09-09

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