WO2004035105A3 - Polymer microneedles - Google Patents

Polymer microneedles Download PDF

Info

Publication number
WO2004035105A3
WO2004035105A3 PCT/IL2003/000818 IL0300818W WO2004035105A3 WO 2004035105 A3 WO2004035105 A3 WO 2004035105A3 IL 0300818 W IL0300818 W IL 0300818W WO 2004035105 A3 WO2004035105 A3 WO 2004035105A3
Authority
WO
WIPO (PCT)
Prior art keywords
layer
irradiated region
radiation sensitive
region
sensitive polymer
Prior art date
Application number
PCT/IL2003/000818
Other languages
French (fr)
Other versions
WO2004035105A2 (en
Inventor
Yehoshua Yeshurun
Meir Hefetz
Erwin Berenschot
Boer Meint De
Dominique Maria Alpeter
Gerrit Boom
Original Assignee
Nano Pass Technologies Ltd
Yehoshua Yeshurun
Meir Hefetz
Erwin Berenschot
Boer Meint De
Dominique Maria Alpeter
Gerrit Boom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL152271A external-priority patent/IL152271A/en
Application filed by Nano Pass Technologies Ltd, Yehoshua Yeshurun, Meir Hefetz, Erwin Berenschot, Boer Meint De, Dominique Maria Alpeter, Gerrit Boom filed Critical Nano Pass Technologies Ltd
Priority to EP03753894A priority Critical patent/EP1559130A2/en
Priority to JP2005501333A priority patent/JP2006502831A/en
Priority to AU2003272053A priority patent/AU2003272053A1/en
Publication of WO2004035105A2 publication Critical patent/WO2004035105A2/en
Publication of WO2004035105A3 publication Critical patent/WO2004035105A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00Basic microelectromechanical structures
    • B81B2203/03Static structures
    • B81B2203/0361Tips, pillars

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The method including disposing a first layer of a radiation sensitive polymer on to a working surface and selectively irradiating the first layer such that the first layer has at least one irradiated region and at least one non-irradiated region. The method also including developing the first layer so as to selectively remove one of the at least one irradiated region and the at least one non-irradiated region such that, at least part of at least one remaining region at least partially defines a form of at least part of a microneedle structure. A microneedle structure including a plurality of microneedles at least partially formed from a radiation sensitive polymer.
PCT/IL2003/000818 2002-10-13 2003-10-09 Polymer microneedles WO2004035105A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP03753894A EP1559130A2 (en) 2002-10-13 2003-10-09 Polymer microneedles
JP2005501333A JP2006502831A (en) 2002-10-13 2003-10-09 Resin microneedle
AU2003272053A AU2003272053A1 (en) 2002-10-13 2003-10-09 Polymer microneedles

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL152271 2002-10-13
IL152271A IL152271A (en) 2002-10-13 2002-10-13 Microneedles structures and production methods
US10/397,359 US6924087B2 (en) 2002-10-13 2003-03-27 Polymer microneedles
US10/397,359 2003-03-27

Publications (2)

Publication Number Publication Date
WO2004035105A2 WO2004035105A2 (en) 2004-04-29
WO2004035105A3 true WO2004035105A3 (en) 2004-09-30

Family

ID=32109297

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2003/000818 WO2004035105A2 (en) 2002-10-13 2003-10-09 Polymer microneedles

Country Status (4)

Country Link
EP (1) EP1559130A2 (en)
JP (1) JP2006502831A (en)
AU (1) AU2003272053A1 (en)
WO (1) WO2004035105A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE490037T1 (en) * 2004-08-16 2010-12-15 Functional Microstructures Ltd METHOD FOR PRODUCING A MICRONEEDLE OR A MICROIMPLANT
WO2006075716A1 (en) * 2005-01-14 2006-07-20 Fujikura Ltd. Drug delivery instrument and method of producing the same
JP5028872B2 (en) * 2006-03-02 2012-09-19 凸版印刷株式会社 Manufacturing method of needle-shaped body
US9394547B2 (en) 2012-01-03 2016-07-19 City University Of Hong Kong Method and apparatus for delivery of molecules to cells
US9526884B2 (en) 2012-11-16 2016-12-27 City University Of Hong Kong Mechanically robust fast-dissolving microneedles for transdermal drug and vaccine delivery
CN107405477B (en) * 2015-03-18 2020-06-16 凸版印刷株式会社 Drug administration device and method for manufacturing drug administration device
US11717660B2 (en) 2021-07-29 2023-08-08 Nanopass Technologies Ltd. Silicon microneedle structure and production method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093520A (en) * 1994-09-09 2000-07-25 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College High aspect ratio microstructures and methods for manufacturing microstructures
US20020155737A1 (en) * 2000-08-21 2002-10-24 The Cleveland Clinic Foundation Microneedle array module and method of fabricating the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093520A (en) * 1994-09-09 2000-07-25 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College High aspect ratio microstructures and methods for manufacturing microstructures
US20020155737A1 (en) * 2000-08-21 2002-10-24 The Cleveland Clinic Foundation Microneedle array module and method of fabricating the same

Also Published As

Publication number Publication date
JP2006502831A (en) 2006-01-26
EP1559130A2 (en) 2005-08-03
AU2003272053A8 (en) 2004-05-04
AU2003272053A1 (en) 2004-05-04
WO2004035105A2 (en) 2004-04-29

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