WO2004024058A3 - Molecules with antitumor activity and chemical synthesis - Google Patents

Molecules with antitumor activity and chemical synthesis Download PDF

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Publication number
WO2004024058A3
WO2004024058A3 PCT/BR2003/000128 BR0300128W WO2004024058A3 WO 2004024058 A3 WO2004024058 A3 WO 2004024058A3 BR 0300128 W BR0300128 W BR 0300128W WO 2004024058 A3 WO2004024058 A3 WO 2004024058A3
Authority
WO
WIPO (PCT)
Prior art keywords
antitumor activity
molecules
chemical synthesis
acridine
synthesis
Prior art date
Application number
PCT/BR2003/000128
Other languages
French (fr)
Other versions
WO2004024058A2 (en
Inventor
Rocha Pitta Ivan Da
De Lima Maria Do Carmo Alves
Galdino Suely Lins
Jacques Barbe
Original Assignee
Conselho Nacional Cnpq
Rocha Pitta Ivan Da
De Lima Maria Do Carmo Alves
Galdino Suely Lins
Jacques Barbe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conselho Nacional Cnpq, Rocha Pitta Ivan Da, De Lima Maria Do Carmo Alves, Galdino Suely Lins, Jacques Barbe filed Critical Conselho Nacional Cnpq
Publication of WO2004024058A2 publication Critical patent/WO2004024058A2/en
Publication of WO2004024058A3 publication Critical patent/WO2004024058A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Synthesis and structure of news acridine-thiazolidine-thiazacridine and acridine-imidaziolidine-imidazacridine compounds with antitumor activity and their therapeutic use as anticancer agents.
PCT/BR2003/000128 2002-09-10 2003-09-09 Molecules with antitumor activity and chemical synthesis WO2004024058A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0203747-5 2002-09-10
BR0203747-5A BR0203747A (en) 2002-09-10 2002-09-10 Molecules with antitumor activity and process for obtaining them

Publications (2)

Publication Number Publication Date
WO2004024058A2 WO2004024058A2 (en) 2004-03-25
WO2004024058A3 true WO2004024058A3 (en) 2004-05-27

Family

ID=31983570

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2003/000128 WO2004024058A2 (en) 2002-09-10 2003-09-09 Molecules with antitumor activity and chemical synthesis

Country Status (2)

Country Link
BR (1) BR0203747A (en)
WO (1) WO2004024058A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20042475A1 (en) * 2004-12-23 2005-03-23 Cell Therapeutics Europe Srl USE OF THIAZOLIDINONIC DERIVATIVES AS THERAPEUTIC AGENTS
EP2298308B1 (en) * 2005-11-14 2013-01-16 University Of Southern California Integrin-binding small molecules
BRPI0601827A (en) * 2006-03-24 2007-11-27 Univ Fed Pernambuco molecules with antitumor activity
BRPI1101273B1 (en) * 2011-03-10 2022-07-19 Universidade Federal De Pernambuco IMIDAZOLIDINE AND THIAZOLDINE MOLECULES WITH ANTI-T.CRUZI ACTIVITIES
WO2013053034A2 (en) * 2011-10-10 2013-04-18 Universidade Federal De Pernambuco - Ufpe Thiazacridines used in anti-cancer therapy
CN107954938A (en) * 2017-12-01 2018-04-24 苏州艾缇克药物化学有限公司 A kind of synthetic method of 1H- imidazoles -4- formic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SILVA, T.G. ET AL.: "Synthesis and structural elucidation of new benzylidene imidazolidines and acridinylidene thiazolidines", HETEROCYCL. COMMUN., vol. 7, no. 6, 2001, pages 523 - 528, XP002975509 *

Also Published As

Publication number Publication date
BR0203747A (en) 2004-05-25
WO2004024058A2 (en) 2004-03-25

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