WO2004022642A1 - Cyclodextrinpartikel - Google Patents
Cyclodextrinpartikel Download PDFInfo
- Publication number
- WO2004022642A1 WO2004022642A1 PCT/EP2003/009713 EP0309713W WO2004022642A1 WO 2004022642 A1 WO2004022642 A1 WO 2004022642A1 EP 0309713 W EP0309713 W EP 0309713W WO 2004022642 A1 WO2004022642 A1 WO 2004022642A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cyclodextrin
- oil
- cellulose
- methyl
- fluidized bed
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims abstract description 109
- 229920000858 Cyclodextrin Polymers 0.000 title claims abstract description 79
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title claims abstract description 64
- 238000000034 method Methods 0.000 claims abstract description 36
- 239000000126 substance Substances 0.000 claims abstract description 27
- 229920003086 cellulose ether Polymers 0.000 claims abstract description 21
- 125000003118 aryl group Chemical group 0.000 claims abstract description 7
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract description 5
- 229940127557 pharmaceutical product Drugs 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims description 53
- 239000007921 spray Substances 0.000 claims description 38
- 239000003205 fragrance Substances 0.000 claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 230000008569 process Effects 0.000 claims description 22
- 238000005469 granulation Methods 0.000 claims description 18
- 230000003179 granulation Effects 0.000 claims description 18
- 239000000796 flavoring agent Substances 0.000 claims description 12
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 11
- 235000019634 flavors Nutrition 0.000 claims description 11
- 235000013305 food Nutrition 0.000 claims description 10
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 9
- 229960004853 betadex Drugs 0.000 claims description 9
- 239000001116 FEMA 4028 Substances 0.000 claims description 8
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims description 8
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 7
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 7
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 7
- 229920000609 methyl cellulose Polymers 0.000 claims description 5
- 235000010981 methylcellulose Nutrition 0.000 claims description 5
- 239000001923 methylcellulose Substances 0.000 claims description 5
- 230000006911 nucleation Effects 0.000 claims description 3
- 238000010899 nucleation Methods 0.000 claims description 3
- 229920000896 Ethulose Polymers 0.000 claims description 2
- 239000001856 Ethyl cellulose Substances 0.000 claims description 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 2
- 239000001859 Ethyl hydroxyethyl cellulose Substances 0.000 claims description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 2
- 229920003090 carboxymethyl hydroxyethyl cellulose Polymers 0.000 claims description 2
- 229920002678 cellulose Polymers 0.000 claims description 2
- 239000001913 cellulose Substances 0.000 claims description 2
- 235000010980 cellulose Nutrition 0.000 claims description 2
- 229920001249 ethyl cellulose Polymers 0.000 claims description 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 2
- 235000019326 ethyl hydroxyethyl cellulose Nutrition 0.000 claims description 2
- GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 claims description 2
- 229940080345 gamma-cyclodextrin Drugs 0.000 claims description 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
- 229920001450 Alpha-Cyclodextrin Polymers 0.000 claims 1
- HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 claims 1
- 229940043377 alpha-cyclodextrin Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 13
- 239000003921 oil Substances 0.000 description 49
- 235000019198 oils Nutrition 0.000 description 49
- -1 absolute Substances 0.000 description 29
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 16
- 240000007594 Oryza sativa Species 0.000 description 14
- 235000007164 Oryza sativa Nutrition 0.000 description 14
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 14
- 235000009566 rice Nutrition 0.000 description 14
- 238000003860 storage Methods 0.000 description 14
- 239000007789 gas Substances 0.000 description 13
- 239000007967 peppermint flavor Substances 0.000 description 12
- 238000009826 distribution Methods 0.000 description 11
- 239000000047 product Substances 0.000 description 10
- 239000008187 granular material Substances 0.000 description 9
- XMGQYMWWDOXHJM-JTQLQIEISA-N (+)-α-limonene Chemical compound CC(=C)[C@@H]1CCC(C)=CC1 XMGQYMWWDOXHJM-JTQLQIEISA-N 0.000 description 8
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 8
- 235000015218 chewing gum Nutrition 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 8
- 235000001510 limonene Nutrition 0.000 description 8
- 229940087305 limonene Drugs 0.000 description 8
- 230000003647 oxidation Effects 0.000 description 8
- 238000007254 oxidation reaction Methods 0.000 description 8
- 235000015112 vegetable and seed oil Nutrition 0.000 description 8
- LOKPJYNMYCVCRM-UHFFFAOYSA-N 16-Hexadecanolide Chemical compound O=C1CCCCCCCCCCCCCCCO1 LOKPJYNMYCVCRM-UHFFFAOYSA-N 0.000 description 7
- 229940112822 chewing gum Drugs 0.000 description 7
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 6
- 229940097362 cyclodextrins Drugs 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 150000002148 esters Chemical class 0.000 description 6
- WPFVBOQKRVRMJB-UHFFFAOYSA-N hydroxycitronellal Chemical compound O=CCC(C)CCCC(C)(C)O WPFVBOQKRVRMJB-UHFFFAOYSA-N 0.000 description 6
- 150000002576 ketones Chemical class 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- DTUQWGWMVIHBKE-UHFFFAOYSA-N phenylacetaldehyde Chemical compound O=CCC1=CC=CC=C1 DTUQWGWMVIHBKE-UHFFFAOYSA-N 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 235000012773 waffles Nutrition 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 5
- 238000011156 evaluation Methods 0.000 description 5
- 230000014759 maintenance of location Effects 0.000 description 5
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 5
- 235000007586 terpenes Nutrition 0.000 description 5
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 4
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 4
- ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 description 4
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 description 4
- QUKGYYKBILRGFE-UHFFFAOYSA-N benzyl acetate Chemical compound CC(=O)OCC1=CC=CC=C1 QUKGYYKBILRGFE-UHFFFAOYSA-N 0.000 description 4
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical class CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 4
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 4
- VAMXMNNIEUEQDV-UHFFFAOYSA-N methyl anthranilate Chemical compound COC(=O)C1=CC=CC=C1N VAMXMNNIEUEQDV-UHFFFAOYSA-N 0.000 description 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 4
- 229920006395 saturated elastomer Polymers 0.000 description 4
- 230000001953 sensory effect Effects 0.000 description 4
- 238000001694 spray drying Methods 0.000 description 4
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- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 4
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 3
- 235000007173 Abies balsamea Nutrition 0.000 description 3
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000004857 Balsam Substances 0.000 description 3
- QMMFVYPAHWMCMS-UHFFFAOYSA-N Dimethyl sulfide Chemical compound CSC QMMFVYPAHWMCMS-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
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Classifications
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- A—HUMAN NECESSITIES
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L23/00—Soups; Sauces; Preparation or treatment thereof
- A23L23/10—Soup concentrates, e.g. powders or cakes
-
- A—HUMAN NECESSITIES
- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
- A21D13/00—Finished or partly finished bakery products
- A21D13/40—Products characterised by the type, form or use
- A21D13/45—Wafers
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- A—HUMAN NECESSITIES
- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
- A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
- A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/72—Encapsulation
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/75—Fixation, conservation, or encapsulation of flavouring agents the flavouring agents being bound to a host by chemical, electrical or like forces, e.g. use of precursors
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A—HUMAN NECESSITIES
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- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
- C08J3/122—Pulverisation by spraying
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
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- A—HUMAN NECESSITIES
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- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
- C08J2305/16—Cyclodextrin; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
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- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
Definitions
- the present invention relates to aroma and / or fragrance-containing cyclodextrin particles containing cellulose ethers with a particle size in the range from 50 to 1000 ⁇ m, products containing these particles, a process for their preparation and their use in foods, pharmaceutical products and consumer articles.
- Cyclodextrins are oligomers of anhydroglucose building blocks that have alpha-1,4
- Bonds are linked to a ring-shaped molecule.
- alpha (6 building blocks) beta (7 building blocks) and gamma (8 building blocks) cyclodextrins. These are usually made from starch by enzymatic processes.
- the circular structure of the cyclodextrins enables inclusion complexes to be formed at the molecular level.
- geometry e.g., the geometry and the geometry of the cyclodextrins.
- the inclusion compounds can be more or less completely formed from the polarity of the flavoring substances.
- Flavorings are mostly volatile compounds that have high loss rates during storage or processing, for example in the food industry, due to evaporation or oxidation. In cyclodextrin complexes, flavorings can be protected against these losses.
- Aroma substances and odoriferous substances or aromas and odoriferous substance mixtures are generally volatile, mostly liquid substances or complex mixtures of these substances. It is customary to encapsulate these substances or mixtures of substances by spray drying, in which, however, only relatively fine and irregularly structured particles are obtained.
- cyclodextrins include the mixing of cyclodextrin solutions, suspensions or pastes (usually in water) and the flavoring and / or fragrance substances. Depending on the polarity of the aroma and / or fragrance, a two-phase mixture is usually created. Increased shear forces are therefore used to accelerate the process, for example by stirring or kneading. This stage is usually followed by a drying step, such as spray, freeze or fluidized bed drying.
- EP-A 392 608 describes a method for producing powdery cyclodextrin complexes whose particle size is less than 12, preferably less than 5 ⁇ m. Processes such as spray drying and freeze drying are used.
- the disadvantage here is the small particle size for the application. Finely divided cyclodextrin complexes are very difficult to disperse in water, which reduces the solubility rate. In addition, when small (typically ⁇ 10 ⁇ m) cyclodextrin particles are used in dry mixtures, which mainly contain components with a particle size between 50 to 500 ⁇ m, there is a risk of segregation.
- the cyclodextrin complex particles have particle sizes of at least 50 ⁇ m.
- some of the aroma and / or fragrance substances remain on the particle surface. This so-called surface oil leads to a reduction in the oxidation stability and further reduces the pourability. The lowest possible proportion of surface oil is desirable.
- DE-A 31 05 666 describes a process in which particles with a particle size of 500 to 1000 ⁇ m are produced with the aid of the addition of binders to cyclodextrin complex mixtures in a kneader with subsequent drying and grinding.
- a disadvantage of such a kneading process is a high proportion of surface oil in the finished granulate.
- the use of several process steps is disadvantageous from the point of view of the production costs.
- EP-A 1 064 856 describes particles containing carbohydrates and / or polyhydroxy compounds with sizes in the range from 100 to 400 ⁇ m.
- the multi-stage process for the production of these particles described there comprises, in addition to spray drying, further stages. In one of these stages, the smaller particles formed in the process are returned so that they grow into the particle size range mentioned by agglomeration. Disadvantages of these particles are their low abrasion stability and their surface oil content.
- the object of the present invention was to provide aroma and / or fragrance-containing cyclodextrin particles with a size of at least 50 ⁇ m, which remedy the above-mentioned disadvantages of the prior art and the simplest possible method for producing such particles. A narrow particle size distribution would also be advantageous.
- the present invention therefore relates to aroma and / or fragrance-containing cyclodextrin particles with a particle size in the range from 50 to 1000 ⁇ m containing a cellulose ether obtainable by a one-stage fluidized bed process a spray mixture, the gas inlet temperature being 80 to 180 ° C and the gas outlet temperature 40 to 95 ° C
- Another object of the present invention is a method for producing cyclodextrin particles, characterized in that an aqueous spray mixture which contains at least one cyclodextrin, at least one aroma and / or fragrance and at least one cellulose ether is introduced into a single-stage fluidized bed device.
- the invention further relates to products containing the cyclodextrin particles according to the invention and the use of the cyclodextrin particles according to the invention in foods, pharmaceutical products and commodities.
- Known ner granulation processes can be used to produce the particles from the spray mixture.
- the processes which are suitable according to the invention are in one stage, i.e. the spray mixture is fed to a single apparatus and the production is ended when the apparatus leaves the apparatus and the finished cyclodextrin particles are present.
- the one-stage process does not produce an intermediate product.
- the particles can be produced by continuous fluidized bed spray granulation, for example according to EP-A 163 836, or by discontinuous fluidized bed spray granulation, for example according to EP-A 70 719.
- a method as described in WO-A 97/16078 for the production of flavor granules in a conventional discontinuously operated fluid bed rotor granulator can also be used.
- the method is preferably carried out continuously.
- a continuous process is better suited for industrial production and has short dwell times. With the same material throughput, the bed content is lower in the continuous methods of fluidized bed spray granulation than in the discounted nuclear process. Instead of letting the total amount of all particle nuclei grow up at the same time, only a small amount of the particle nuclei is sprayed in the continuous fluidized bed spray granulation and is discharged immediately after reaching the desired particle size, for example via a sifter.
- the encapsulated aroma and / or fragrance-containing cyclodextrin particles produced according to the invention have a small particle size distribution; in addition, the particles (granules) of the desired size can be removed in a targeted manner.
- the fluidized bed has a low bed height. This is preferably 3 to 50 cm, particularly preferably 5 to 20 cm.
- Continuous fluidized bed spray granulation creates free-flowing, low-dust, granular particles from a spray mixture.
- the basic processes of germ generation, drying, shaping and selective discharge of the particles, which have reached the desired particle size, take place simultaneously in a granulating apparatus.
- Variants have been realized. A distinction must be made in particular between the variant with external nucleation, in which germs from external classifiers, grinding plants or other solid storage are dosed into the bed, and variants with internal nucleation.
- classifiers are preferably used for the discharge of the particles, as described, for example, in EP-A 332 031. With the classifiers it is achieved that only the coarse particles can leave the fluidized bed. The remaining particles remain in the fluidized bed until they have reached the desired particle size.
- an aqueous spray mixture is first prepared.
- this spray mixture contains at least one cyclodextrin, flavoring and / or fragrance substances and at least one cellulose ether.
- the particles according to the invention are produced from this spray mixture in one process step in a fluidized bed apparatus with particle sizes of greater than or equal to 50 ⁇ m.
- Particles according to the invention have a particle size of 50 ⁇ m to 1000 ⁇ m. Particles with a particle size of 70 ⁇ m to 500 ⁇ m are preferred, particularly preferably from 100 to 300 ⁇ m.
- the information on particle sizes relate to the particle diameter and are taken from the distribution sum curves. These distribution sum curves represent the dependence of the distribution sum Q3 (x) on the particle diameter x.
- the distribution sum Q 3 (x) is the normalized total quantity of all particles with a diameter less than or equal to x.
- the index 3 indicates that 'the type of the measured quantity is the volume (Ulimanns Encyklopadie der Technische Chemie, Volume 2, Maschinenstechnik I, 4th edition, Verlag Chemie, Weinheim, 1972, p. 24 -34).
- Particle size determination via volume distribution can be done by laser diffraction
- Suitable cyclodextrins are alpha, beta, gamma and substituted cyclodextrins. Alpha, beta, gamma cyclodextrin or mixtures thereof are advantageous, beta cyclodextrin is preferred. In a preferred embodiment, the cyclodextrin portion of the spray mixture consists only of beta-cyclodextrin.
- the cyclodextrin content in the spray mixture is advantageously 5 to 50% by weight, preferably 10 to 40% by weight, particularly preferably 15 to 30%
- the water content in the spray mixture is advantageously 40 to 95% by weight, preferably 50 to 90% by weight, particularly preferably 60 to 80% by weight.
- the proportion of the aroma and / or fragrance substances in the spray mixture is advantageously from 0.0005 to 15% by weight, preferably from 0.1 to 10% by weight, particularly preferably from 0.25 to 5% by weight.
- the spray mixture contains binders in the form of cellulose ethers as granulation aids.
- the cellulose ether is preferably selected from the group comprising methyl cellulose, ethyl cellulose, propyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, carboxymethyl cellulose, carboxymethyl hydroxyethyl cellulose and ethyl hydroxyethyl cellulose, carboxymethyl cellulose (CMC) is particularly preferred.
- a content of cellulose ether in the spray mixture is preferably from 0.1 to 6% by weight, particularly preferably from 0.2 to 2% by weight.
- the dried particles preferably contain between 0.5 to 10% by weight, particularly preferably between 2 to 4.5% by weight, of cellulose ether.
- Cellulose ethers with a viscosity of 15 to 200,000 mPas are advantageous, preferably those with a viscosity of 1,000 to 50,000 mPas, particularly preferably those with a viscosity of 5,000 to 15,000 mPas.
- the viscosity data relate to a 2% strength by weight solution in water at 20 ° C.
- a cone and plate system with a diameter of 40 mm and a cone angle of 4 ° was used as the measuring system.
- the shear rate was 1 s "1 , the temperature was 20 ° C.
- the viscosity can be determined, for example, with the rheometer CVO 120 (Bohlin Instruments GmbH, Pforzheim).
- the aroma and / or fragrance content in the finished cyclodextrin particle is 0.01 to 30% by weight, preferably 1 to 15% by weight and particularly preferably 5 10 '% by weight.
- flavorings and / or fragrances which can be part of the cyclodextrin particles according to the invention can be found, for example, in S. Arctander, Perfume and Flavor Chemicals, Vol. I and LI, Montclair, NJ, 1969, Dverlag or K. Bauer, D. Garbe and H. Surburg, Common Fragrance and Flavor Materials, 4 th Ed., Wiley-VCH, Weinheim 2001.
- extracts from natural raw materials such as essential oils
- Amyrisöl Angelica seed oil; Angelica root oil; anise oil; Valerian oil; Basil oil; Baummoos -Absolue; Bay oil; Mugwort oil; Benzoeresin; Bergamot oil; beeswax
- Fennel oil Pine needle oil; galbanum; Galbanumresin; geranium; Grapefruit oil;
- guaiac wood gurjun balsam
- gurjun balsam oil Helichrysum absolute; Helichrysum oil; Ginger oil; Iris root absolute; Orris root oil; Jasmine absolute; calamus; Chamomile oil blue; Roman chamomile oil; Carrot seed oil; Kaskarillaöl; Pine needle oil;
- Lavandin absolute Lavandin oil; Lavender absolute; Lavender oil; Lemongrass oil; Loving stick oil; Distilled lime oil; Lime oil pressed; linaloe; Litsea cubeba oil;
- Olibanum absolute olibanum
- Opopanaxöl Orange blossom absolute
- Orange oil
- Palmarosa oil palmarosa oil; patchouli oil; perilla oil; Peruvian balsam oil; Parsley leaf oil;
- Parsley seed oil Parsley seed oil; Petitgrain oil; Peppermint oil; Pepper oil; chilli; pine oil; Poleyöl; Rose absolute; Rosewood oil; Rose oil; Rosemary oil; Dalmatian sage oil; Sage oil spanish; sandalwood; Celery seed oil; spike lavender oil; star anise; Styraxöl; tagetes; Pine needle oil; Tea-tree oil; turpentine; Thyme oil; Tolu; Tonka absolute; Tuberose absolute; Vanilla extract; Violet leaf absolute; verbena; vetiver; Juniper berry oil; Wine yeast oil; Wormwood oil; Wintergreen oil; ylang oil; hyssop oil; Civet absolute; cinnamon leaf; cinnamon bark oil; and fractions thereof, or ingredients isolated therefrom;
- fragrances from the group of hydrocarbons such as B. 3-carene; ⁇ -pinene; beta-pinene; ⁇ -terpinene; ⁇ -terpinene; p-cymene; bisabolene; camphene; caryophyllene; cedrene; farnesene; limonene; longifolene; myrcene; ocimene; valencene; (E, Z) -l, 3,5-undecatriene;
- the aliphatic ketones and their oximes such as e.g. 2-heptanone; 2-octanone; 3-octanone; 2-nonanone; 5-methyl-3-heptanone; 5-methyl-3-heptanone oxime; 2,4,4,7-
- Tetramethyl-6-octen-3-one Tetramethyl-6-octen-3-one; the aliphatic sulfur-containing compounds such as 3-methylthiohexanol; 3-Methylthiohexylacetat; 3-mercaptohexanol; 3-mercapto-hexyl acetate; 3-mercaptohexyl butyrate; 3-acetylthiohexyl acetate; l-menthene-8-thiol; aliphatic nitriles such as 2-nonenenitrile; 2-Tridecenklaitril; 2, 12-tridecadienonitrile; 3,7-dimethyl-2,6-octadienklanklanitrile;
- aliphatic carboxylic acids and their esters such as e.g. (E) - and (Z) -3-hexenyl formate; ethylacetoacetate; isoamyl; hexyl acetate; 3,5,5-trimethylhexyl acetate; 3-methyl-2-butenyl acetate; (E) -2-hexenyl acetate; (E) - and (Z) -3-hexenyl acetate; Octyl acetate; 3-octyl acetate; l-octen-3-yl acetate; ethyl butyrate; Butyl butyrate,; Isoamylbutyrate; hexyl butyrate; (E) - and (Z) -3-hexenyl isobutyrate; hexyl crotonate; Ethyl isovalate; Ethyl 2-methylpentanoate; ethylhexan
- acyclic terpene alcohols e.g. citronellol; geraniol; nerol; linalool; Lavadulol; nerolidol; farnesol; tetrahydrolinalool; tetrahydrogeraniol;
- acyclic terpene aldehydes and ketones such as e.g. geranial; neral; citronellal; 7-hydroxy-3, 7-dimethyloctanal; 7-methoxy-3, 7-dimethyloctanal; 2,6,10-trimethyl-9-undecenal; geranyl acetone; as well as the dimethyl and diethyl acetals of geranial, neral, 7-hydroxy-3,7-dimethyloctanal;
- cyclic terpene alcohols such as menthol; isopulegol; alpha-terpineol; Terpinenol-4; Menthane-8-ol; Menthane-1-ol; Menthane-7-ol; borneol; soborneol; Linoline oxide; monopoly; cedrol; ambrinol; vetiver; guaiol; as well as their formates, acetates, propionates, isobutyrates, butyrates, isovalerianates, pentanoates, hexanoates, crotonates, tiglinates, 3-methyl-2-butenoates; cyclic terpene aldehydes and ketones such as menthone; menthone; 8-mer captomenthan-3-one; carvone; camphor; fenchon; alpha-ionone; beta-ionone; alpha-n-methyl ionone; beta-n-methylionone; alpha-is
- cyclic alcohols such as e.g. 4-tert.-butylcyclohexanol; 3,3,5-trimethylcyclohexanol; 3-isocamphylcyclohexanol; 2,6,9-trimethyl-Z2, Z5, E9-cyclododecatrien-l-ol; 2-isobutyl-4-methyl tetrahydro-2H-pyran-4-ol;
- cycloahphatic alcohols such as e.g. alpha, 3,3-trimethylcyclohexylmethanol
- cyclic and cycloahphatic ethers such as e.g. cineol; cedryl methyl ether; cyclododecyl; (Ethoxymethoxy) cyclododecane; alpha-Cedrenepoxid; 3a, 6,6,9a-tetramethyl-dodecahydronaphtho [2, l-b] furan; 3a-ethyl-6,6,9a-trimethyl-dodecahydronaphtho [2, l-b] furan; 1,5,9-trimethyl-13-oxabicyclo [10.1.0] trideca-4,8-diene; rose oxide; 2- (2,4-dimethyl-3-cyclohexen-l-yl) -5-methyl-5- (l-methylpropyl) -1,3-dioxane;
- cyclic ketones such as 4-tert-butylcyclohexanone; 2,2,5-trimethyl-5-pentylcyclopentanone; 2-heptylcyclopentanone; 2-pentylcyclopentanone; 2-hydroxy-3- methyl-2-cyclopenten-1-one; 3-methyl-cis-2-penten-1-yl-2-cyclopenten-1-one;
- cycloaliphatic aldehydes such as e.g. 2,4-dimethyl-3-cyclohexene carbaldehyde; 2
- cycloaliphatic ketones such as. B. l- (3,3-Dimethylcyclohexyl) -4-penten-l-one; 1 - (5,5-dimethyl-1-cyclohexen- 1 -yl) -4-penten-l -one; 2,3,8,8-tetramethyl-l, 2,3,4,5,6,7,8-octahydro-2-naphthalenyl methyl ketone; Methyl 2,6,10-trimethyl-2,5,9-cyclododecatrienyl ketone; tert-butyl (2,4-dimethyl-3-cyclohexen-l-yl) ketone;
- esters of cyclic alcohols such as e.g. 2-tert-butylcyclohexyl acetate; 4-tert butyl cyclohexyl acetate; 2-tert-pentylcyclohexyl acetate; 4-tert-pentylcyclohexyl acetate; Deca- hydro-2-naphthylacetate; 3-pentyltetrahydro-2H-pyran-4-ylacetate; Decahydro-2,5,5,8a-tetramethyl-2-naphthylacetate; 4,7-methano-3a, 4,5,6,7,7a-hexahydro-5, or
- 6-indenyl acetate 4,7-methano-3a, 4,5,6,7,7a-hexahydro-5, or 6-indenylpropionate; 4,7-methano-3a, 4,5,6,7,7a-hexahydro-5, or 6-indenyl isobutyrate; 4,7-methanooctahydro-5 or 6-indenyl acetate;
- ester of cycloaliphatic carboxylic acids such as. B. allyl-3-cyclohexylpropionate;
- aromatic hydrocarbons such.
- ester of arahmic alcohols and aliphatic carboxylic acids such as; benzyl acetate; benzylpropionate; benzyl isobutyrate; Benzylisovalerianat;
- aromatic and arahatic carboxylic acids and their esters such as e.g. Benzoic acid; phenylacetic acid; methylbenzoate; ethyl benzoate; hexyl benzoate; Benzyl benzoate; methyl phenylacetate; ethyl phenylacetate; geranyl phenylacetate; Phenylethylphenyl acetate; Methylcmnmat; ethylcinnamate; Benzyl; Phenylethylcinnamat; cinnamyl cinnamate; allyl phenoxyacetate; methyl salicylate; isoamyl; Hexyl salicylate; cyclohexyl; Cis-3-hexenyl salicylate; benzyl; Phenylethyl salicylate; Methyl-2,4-dihydroxy-3,6-dimethylbenzoate; Ethyl 3-phenylg
- the nitrogenous aromatic compounds such as e.g. 2,4,6-trinitro-l, 3-dimethyl-5-tert-butylbenzene; 3,5-dinitro-2,6-dimethyl-4-tert.-butylacetophenone; Cinnamic acid nitrile; 5-phenyl-3-methyl-2-penten Aciditril; 5-phenyl-3-methylpentanoic acid nitrile; methyl anthranilate; Methyl N-methylanthranilate; See bases of methyl anthranilate with 7-hydroxy-3,7-dimethyloctanal, 2-methyl-3- (4-tert-butylphenyl) propanal or 2,4-dimethyl-3-cyclohexenecarbaldehyde; 6-Isopropyl; 6-isobutylquinoline; 6-sec-butylquinoline; indole; skatol; 2-methoxy-3-isopropy ⁇ pyrazm; 2-isobutyl-3
- phenols, phenyl ethers and phenyl esters such as, for example, estragole; anethole; eugenol; Eugenylmethylether; isoeugenol; Isoeugenylmethylether; thymol; carvacrol; Diphenyl ether; beta-naphthyl methyl ether; beta-Naphthylethylether; beta-naphthyl isobutyl ether; 1,4-dimethoxybenzene; Eugenylacetat; 2-methoxy-4-methyl phenol; 2-ethoxy-5- (l-propenyl) phenol; p-Kresylphenylacetat; the heterocyclic compounds such as 2,5-dimethyl-4-hydroxy-2H-furan-3-one; 2-ethyl-4-hydroxy-5-methyl-2H-furan-3-one; 3-hydroxy-2-methyl-4H-pyran-4-one; 2-ethyl-3-hydroxy-4H
- lactones such as 1,4-octanolide; 3-methyl-1,4-octanolide; 1,4-nonanolide; 1,4-
- flavorings that can be part of the cyclodextrin particles are in addition to all of the above.
- Benzyl acetate, methyl salicylate organic ahphatic acids (saturated and unsaturated) e.g. Butyric acid, acetic acid, caproic acid; organic aromatic acids; ahphatic alcohols (saturated and unsaturated) e.g. Ethanol, propylene glycol, octenol, 3-ocetenol, cis-3-hexenol; cyclic alcohols e.g. Menthol; aromatic alcohols e.g. benzyl alcohol; ahphatic aldehydes (saturated and unsaturated) e.g. Acetaldehyde, nonadienal; aromatic aldehydes e.g.
- benzaldehyde Ketones e.g. Menton; cyclic ethers e.g. 4-hydroxy-5-methyliuranon; aromatic ethers e.g. p-methoxybenzaldehyde, guaiacol; Phenol ethers e.g. Methoxyvinylphenol; Acetals e.g. acetaldehyde; Lactones e.g. gamma-decalactone; Terpenes e.g. Lime, linalool, terpinene, terpineol, citral (geranial and neral); sulfur-containing compounds e.g.
- the cyclodextrin particles according to the invention are particularly suitable for encapsulating very odor-intensive, highly volatile, easily oxidizable, difficult to dose manageable and / or irritating substances.
- acetaldehyde, allyl isothiocyanate, limonene, cis-3-hexenol, citral, methylethylpyrazine or also methylthiol may be mentioned, for example.
- the cyclodextrin particles according to the invention can also contain nutritionally active substances or mixtures of substances (nutraceuticals).
- nutritionally active substances include panthenol, pantothenic acid, essential fatty acids, vitamin A and derivatives, carotenes, vitamin C (ascorbic acid), vitamin E (tocopherol) and derivatives, vitamins of the B and D series such as vitamin B 6 (nicotinamide), Vitamin Bj, Vitamin D ls Vitamin D 3 , Vitamin F, folic acid, biotin, amino acids,
- Plant extracts such as B. arnica, aloe, beard lichen, ivy, nettle, ginseng, henna, chamomile, marigold, rosemary, sage, horsetail or thyme.
- Oils such as apricot kernel oil, avocado oil, babassu oil, cottonseed oil, borage oil, safflower oil,
- Peanut oil gamma-oryzanol, rose hip seed oil, hemp oil, hazelnut oil, currant seed oil, jojoba oil, cherry seed oil, salmon oil, linseed oil, corn oil, macadamia nut oil, almond oil, evening primrose oil, mink oil, olive oil, pecan oil, peach seed oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil, rice oil Safflower oil, sesame oil, soybean oil, sunflower oil, tea tree oil, grape seed oil or wheat germ oil.
- cyclodextrin particles according to the invention can also contain further substances, such as, for example, emulsifiers, dyes, antioxidants, stabilizers, UV filters, vitamins and other ingredients customary in the food, personal care, pharmaceutical or fragrance industry.
- the spray mixture can be prepared, for example, as set out in EP-A 1 084 625 or as described below.
- a complex of cyclodextrin and the flavor is formed.
- the cyclodextrin and aroma must be at least partially dissolved.
- Water with a temperature of 10 ° C. to 90 ° C., preferably from 40 ° C. to 70 ° C., particularly preferably between 50 to 60 ° C. is used as the solvent.
- temperatures of 15 to 30 ° C are preferred.
- shear forces are introduced according to the invention.
- the shear forces can be introduced, for example, by stirring or dispersing, for which purpose rotor-stator dispersing tools or high-pressure homogenizers are suitable.
- the batch is advantageously allowed to rest for 0.2 to 24 hours with cooling to 4 to 25 ° C., preferably 8 to 16 hours with cooling to 4 to 7 ° C.
- the resting time is preferably reduced to 15 to 30 minutes at 4 to 7 ° C.
- the cellulose ether can be added to the spray mixture at any time. This can be before the complex formation, during the complex formation, after the complex formation but before the cold storage, during the cold storage or after the cold storage. It is also possible to mix the cellulose ether with the cyclodextrin powder and only then add the water. The total amount of the cellulose ether can also be divided into several portions, ie portioned, and added at any time.
- the ingredients can be added in any order during the production of the spray mixture.
- cyclodextrin and cellulose ether can be mixed, then water added and stirred or dispersed intensively. Subsequently, flavoring and / or fragrance substances are added and the mixture is intensively stirred or dispersed and stored cool.
- An alternative order includes the intensive mixing of water, cellulose ether and flavoring and / or fragrance substances as well as the subsequent addition and the
- cyclodextrin can be added to water and stirred vigorously.
- the aroma is added and dispersed.
- the cellulose ether is added and distributed by stirring or dispersing.
- the granulation is preferably carried out in a granulating apparatus as described in EP-A 163 836.
- the temperature of the spray mixture is chosen such that the aroma or fragrance cyclodextrin complex does not decompose.
- the temperature is usually between 5 and 70 ° C, preferably between 10 and 40 ° C and particularly preferably between 20 and 30 ° C.
- the gas inlet and gas outlet temperatures of the fluidizing gas must be adapted to the respective spray mixture.
- the gas inlet temperatures are 80 to 180 ° C, preferably 100 to 140 ° C and particularly preferably between 120 and 130 ° C.
- the gas outlet temperatures are 40 to 95 ° C, preferably 45 to 70 ° C, particularly preferably 50 to 60 ° C.
- the cyclodextrin particles according to the invention can be used in a large number of products.
- sweets such as lozenges, chewing gum, refreshment tablets, compressed foods, hard caramels, confectionery and chocolate, baked goods such as cakes, waffles and cookies, snacks, instant meals and other histant products (soups,
- Sauces, beverage powders and granules, tea bags, seasonings can be used.
- the cyclodextrin particles are particularly suitable for heated, superheated, kept warm, sterilized or pasteurized foods, such as catering meals, fried foods, chips, flavored breadcrumbs, ready meals, microwave dishes and canned fruit and vegetables.
- Pharmaceutical products can be, for example, lozenges, throat or cough drops, pharmaceutical powders or granules.
- Commodities can be, for example, personal care products, household products, tobacco products (e.g. cigarettes), cosmetic products, washing and cleaning agents, room fresheners, textiles or odor-absorbing agents (e.g. cat litter).
- Personal care products can include oral care products such as toothpastes,
- Tooth gels, tooth creams, dental care chewing gums and mouthwashes are examples of Tooth gels, tooth creams, dental care chewing gums and mouthwashes.
- retention indication in% by weight is understood to mean the weight-related ratio of the amount of flavoring and / or fragrance substances in the finished particle to the amount of flavoring and / or fragrance substances used in the spray mixture.
- beta-cyclodextrin (beta-cyclodextrin Kieptose ®, Fa. Roquette) 431 g d-limonene
- CMC carboxymethyl cellulose
- the water was warmed to 25 ° C, the cyclodextrin was added and the mixture was mixed for 3 minutes with an Ultra Turrax T50 DPX.
- the d-limonene is added and the mixture is dispersed for a further 15 min.
- the carboxymethyl cellulose was added and homogenized using the Ultra Turrax T50 DPX. The batch was then left for a further 15 hours at 20 ° C. and was then fed to the fluidized bed granulation apparatus.
- the spray mixture described above was granulated in a granulating apparatus of the type described in EP-A 163 836 (with the following features: diameter of inflow base: 225 mm, spray nozzle: two-substance nozzle; classifying discharge: zigzag classifier; filter: internal bag filter).
- the temperature of the mixture was 35 ° C. Air was blown in at a rate of 60 kg / h to fluidize the bed contents.
- the inlet temperature of the fluidizing gas was 120 ° C.
- the temperature of the exit gas was 55 ° C. Air was supplied as a sight gas in an amount of 1.5 kg / h at a temperature of 34 ° C.
- the granulation performance was approx. 420 g / h.
- a free-flowing granulate with an average particle size of 131.7 ⁇ m and a bulk density of 470 g / 1 was obtained.
- the granules had a smooth surface and a spherical, largely spherical geometry. Due to the constant pressure loss of the filter and the constant bed content, steady-state conditions with regard to the granulation process can be assumed.
- the water was heated to 50 ° C., the cyclodextrin was added and the mixture was mixed for 3 minutes with an Ultra Turrax T50 DPX. The d-limonene was added and the mixture was dispersed for a further 15 min.
- the carboxymethyl cellulose was added and homogenized using the Ultra Turrax mixer.
- the batch was then left at 6 ° C. for a further 15 hours and (storage) was then fed to the fluidized bed granulation apparatus from Example 1.
- the entry temperature of the fluidizing gas was 125 ° C.
- the temperature of the exit gas was 49 ° C.
- the granulation performance was approx. 570 g / h.
- a free-flowing granulate with an average particle size of 165.8 ⁇ m and a bulk density of 460 g / 1 was obtained.
- the cyclodextrin particles had a smooth surface and a spherical, largely spherical geometry.
- CMC carboxymethyl cellulose
- the water was heated to 50 ° C., the cyclodextrin was added and the mixture was mixed for 3 minutes with an Ultra Turrax T50 DPX. After the addition of the peppermint aroma, the batch was mixed for a further 15 min with the Ultra Turrax T50 DPX. CMC was added and resolved with the Ultra Turrax.
- compositions of spray mixtures relate to quantities used in grams.
- Table 1 shows the advantages with regard to oxidation stability, flowability and redispersibility of the particles produced in accordance with the invention over particles which were produced according to the prior art.
- the better oxidation stability is due to the low proportion of surface oil.
- the pourability was determined in accordance with DTN ISO 4324.
- An angle of repose ⁇ 30 ° means very good flowability, an angle of repose between 30 ° and 40 ° means free flowability and pour angle> 45 ° mean poor flowability (see also Uhlemann, M Kunststoffl: fluidized bed spray granulation, Springer-Verlag Berlin, 2000, p. 169).
- the sensitivity to oxidation was determined after storage times of one day or 180
- the redispersibility was examined as follows: In a beaker, 20 ml of water (20 ° C) of the respective particle, and 200 mg were added and stirred with a magnetic stirrer for 1 minute at 200 min "1 The evaluation was made on a..
- Example 16 Peppermint-flavored chewing gum
- a chewing gum (B) 2% by weight of peppermint flavor-cyclodextrin articles from Example 3 (corresponding to 0.18% by weight flavor) and 1.12% by weight of peppermint flavor were incorporated in liquid form.
- a chewing gum (A) was produced which contained 1.30% by weight of peppermint flavor in liquid form.
- Sensory time-intensity studies with a trained group of testers (12 people) showed a significantly higher taste intensity for chewing gum (B) with peppermint flavor particles. After 15 minutes, the flavor intensity of the sample containing the peppermint aroma cyclodextrin articles was twice as high.
- A chewing gum with liquid peppermint flavor
- Peppermint flavor intensity was rated on a scale from 0 (no peppermint flavor) to 10 (very strong peppermint flavor).
- Example 17 Waffle
- the limonene cyclodextrin articles from Example 2 were placed at 1.2% by weight (corresponding to 0.1% by weight of flavor) in a waffle batter consisting of flour, water, sugar, lecithin, salt and peanut oil. Waffles were baked at a temperature of 200 ° C for 1 minute. For comparison, liquid limonene with the same concentration was incorporated into a dough of the same composition. The sensory evaluation of fresh goods (1 day old) showed a higher aroma intensity in the waffles with limonene cyclodextrin articles. The sensory evaluation could be confirmed analytically, as shown in Table 2.
- the sensory evaluation of the aroma intensity of the lime note and the off-flavor was carried out after 4 months of storage at 20 ° C. on a scale from 0 (imperceptible) to 5 (very strong).
- cis-3-hexenol-cyclodextrin particles which were produced analogously to Example 1, were added to a powder mixture comprising salt, starch, spice powder, fat powder and dried vegetables.
- the set particle size of 100 to 200 ⁇ m gives the following advantages during the mixing process: dust-free, low risk of segregation, good pourability.
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03793785A EP1537174A1 (de) | 2002-09-04 | 2003-09-02 | Cyclodextrinpartikel |
AU2003264145A AU2003264145A1 (en) | 2002-09-04 | 2003-09-02 | Cyclodextrin particle |
US10/476,828 US7348035B2 (en) | 2002-09-04 | 2003-09-02 | Cyclodextrin particle |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10240698A DE10240698A1 (de) | 2002-09-04 | 2002-09-04 | Cyclodextrinpartikel |
DE10240698.7 | 2002-09-04 |
Publications (1)
Publication Number | Publication Date |
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WO2004022642A1 true WO2004022642A1 (de) | 2004-03-18 |
Family
ID=31724288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/009713 WO2004022642A1 (de) | 2002-09-04 | 2003-09-02 | Cyclodextrinpartikel |
Country Status (6)
Country | Link |
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US (1) | US7348035B2 (de) |
EP (1) | EP1537174A1 (de) |
CN (1) | CN1329440C (de) |
AU (1) | AU2003264145A1 (de) |
DE (1) | DE10240698A1 (de) |
WO (1) | WO2004022642A1 (de) |
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EP1955601A1 (de) | 2007-01-25 | 2008-08-13 | Symrise GmbH & Co. KG | Verwendung von Propenylphenylglycosiden zur Verstärkung süßer sensorischer Eindrücke |
EP1977655A1 (de) | 2007-03-29 | 2008-10-08 | Symrise GmbH & Co. KG | Aromakompositionen von Alkamiden mit Hesperetin und/oder 4-Hydroxydihydrochalkonen und deren Salzen zur Verstärkung süßer sensorischer Eindrücke |
EP2027136A1 (de) * | 2006-06-13 | 2009-02-25 | Cargill, Incorporated | Grossteilige cyclodextrin-einschlusskomplexe und verfahren zu deren herstellung |
EP2368442A2 (de) | 2005-07-27 | 2011-09-28 | Symrise AG | Verwendung von Hesperetin zur Verstärkung von süßem Geschmack |
WO2013124773A1 (en) * | 2012-02-23 | 2013-08-29 | Bostik S.A. | Dispenser packaging for viscous liquid comprising large particles |
WO2015144485A1 (de) * | 2014-03-28 | 2015-10-01 | Henkel Ag & Co. Kgaa | Olfaktorische verstärker |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3105666A1 (de) * | 1980-02-18 | 1982-01-07 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára RT, 1045 Budapest | Praeparate zur aromatisierung von tee sowie verfahren zur aromatisierung von tee |
JPS58172311A (ja) * | 1982-04-02 | 1983-10-11 | Kodama Kk | 持続性製剤及びその製法 |
EP0163836A1 (de) * | 1984-04-07 | 1985-12-11 | Bayer Ag | Verfahren und Vorrichtung zur Herstellung von Granulaten |
EP0392608A2 (de) * | 1989-04-12 | 1990-10-17 | The Procter & Gamble Company | Festes Verbraucherprodukt, welches feinteilige Cyclodextrin-Komplexe enthält |
JPH07165616A (ja) * | 1993-12-09 | 1995-06-27 | Hisamitsu Pharmaceut Co Inc | シクロデキストリンの複合組成物及び複合化法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5102564A (en) | 1989-04-12 | 1992-04-07 | The Procter & Gamble Company | Treatment of fabric with perfume/cyclodextrin complexes |
CN1073711A (zh) * | 1991-12-27 | 1993-06-30 | 昆明五华香料厂 | 微囊赋香剂及其制备方法与用途 |
CN1188143A (zh) * | 1997-01-13 | 1998-07-22 | 浙江高创科技发展有限公司 | 洗涤用的香料颗粒 |
-
2002
- 2002-09-04 DE DE10240698A patent/DE10240698A1/de not_active Withdrawn
-
2003
- 2003-09-02 CN CNB038210657A patent/CN1329440C/zh not_active Expired - Fee Related
- 2003-09-02 US US10/476,828 patent/US7348035B2/en not_active Expired - Fee Related
- 2003-09-02 WO PCT/EP2003/009713 patent/WO2004022642A1/de not_active Application Discontinuation
- 2003-09-02 AU AU2003264145A patent/AU2003264145A1/en not_active Abandoned
- 2003-09-02 EP EP03793785A patent/EP1537174A1/de not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3105666A1 (de) * | 1980-02-18 | 1982-01-07 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára RT, 1045 Budapest | Praeparate zur aromatisierung von tee sowie verfahren zur aromatisierung von tee |
JPS58172311A (ja) * | 1982-04-02 | 1983-10-11 | Kodama Kk | 持続性製剤及びその製法 |
EP0163836A1 (de) * | 1984-04-07 | 1985-12-11 | Bayer Ag | Verfahren und Vorrichtung zur Herstellung von Granulaten |
EP0392608A2 (de) * | 1989-04-12 | 1990-10-17 | The Procter & Gamble Company | Festes Verbraucherprodukt, welches feinteilige Cyclodextrin-Komplexe enthält |
JPH07165616A (ja) * | 1993-12-09 | 1995-06-27 | Hisamitsu Pharmaceut Co Inc | シクロデキストリンの複合組成物及び複合化法 |
Non-Patent Citations (5)
Title |
---|
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; "Formation of inclusion compounds of drugs with cyclodextrin in presence of water-soluble polymers to improve solubility and stability", XP002262258, retrieved from STN Database accession no. 123:179388 * |
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO,US; "Sustained-release pharmaceuticals containing ethyl cellulose, glycerides and cyclodextrin", XP002262259, retrieved from STN Database accession no. 100:12689 * |
DATABASE WPI Week 198346, Derwent World Patents Index; AN 1983-818128 * |
DATABASE WPI Week 199534, Derwent World Patents Index; AN 1995-261219 * |
PATENT ABSTRACTS OF JAPAN vol. 1995, no. 09 31 October 1995 (1995-10-31) * |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005026002A1 (de) * | 2005-06-03 | 2006-12-14 | Beiersdorf Ag | Kosmetische Zubereitungen mit einem Gehalt an einem wässrigen Anisfruchtextrakt und einem oder mehreren polymeren Verdickungsmitteln, gewählt aus der Gruppe der Cellulosederivate |
EP2368442A2 (de) | 2005-07-27 | 2011-09-28 | Symrise AG | Verwendung von Hesperetin zur Verstärkung von süßem Geschmack |
EP2027136A1 (de) * | 2006-06-13 | 2009-02-25 | Cargill, Incorporated | Grossteilige cyclodextrin-einschlusskomplexe und verfahren zu deren herstellung |
EP2027136A4 (de) * | 2006-06-13 | 2011-08-03 | Cargill Inc | Grossteilige cyclodextrin-einschlusskomplexe und verfahren zu deren herstellung |
EP1955601A1 (de) | 2007-01-25 | 2008-08-13 | Symrise GmbH & Co. KG | Verwendung von Propenylphenylglycosiden zur Verstärkung süßer sensorischer Eindrücke |
EP1977655A1 (de) | 2007-03-29 | 2008-10-08 | Symrise GmbH & Co. KG | Aromakompositionen von Alkamiden mit Hesperetin und/oder 4-Hydroxydihydrochalkonen und deren Salzen zur Verstärkung süßer sensorischer Eindrücke |
WO2013124773A1 (en) * | 2012-02-23 | 2013-08-29 | Bostik S.A. | Dispenser packaging for viscous liquid comprising large particles |
US9327894B2 (en) | 2012-02-23 | 2016-05-03 | Bostik S.A. | Dispenser packaging for viscous liquid comprising large particles |
WO2015144485A1 (de) * | 2014-03-28 | 2015-10-01 | Henkel Ag & Co. Kgaa | Olfaktorische verstärker |
Also Published As
Publication number | Publication date |
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CN1678674A (zh) | 2005-10-05 |
CN1329440C (zh) | 2007-08-01 |
US7348035B2 (en) | 2008-03-25 |
EP1537174A1 (de) | 2005-06-08 |
US20040234479A1 (en) | 2004-11-25 |
AU2003264145A1 (en) | 2004-03-29 |
DE10240698A1 (de) | 2004-03-18 |
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