WO2004011595A3 - Vecteurs destines au transfert de molecules d'interet dans des cellules cibles - Google Patents

Vecteurs destines au transfert de molecules d'interet dans des cellules cibles Download PDF

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Publication number
WO2004011595A3
WO2004011595A3 PCT/FR2003/002344 FR0302344W WO2004011595A3 WO 2004011595 A3 WO2004011595 A3 WO 2004011595A3 FR 0302344 W FR0302344 W FR 0302344W WO 2004011595 A3 WO2004011595 A3 WO 2004011595A3
Authority
WO
WIPO (PCT)
Prior art keywords
interest
target cells
vectors
molecules
cells
Prior art date
Application number
PCT/FR2003/002344
Other languages
English (en)
Other versions
WO2004011595A2 (fr
Inventor
Alphonse Garcia
Frederic Dessauge
Veronique Hospital
Gordon Langsley
Santos Susin
Xavier Cayla
Julien Guergnon
Angelita Rebollo
Original Assignee
Pasteur Institut
Centre Nat Rech Scient
Agronomique Inst Nat Rech
Consejo Superior De Inverstiga
Univ Paris Vii
Univ Paris Curie
Alphonse Garcia
Frederic Dessauge
Veronique Hospital
Gordon Langsley
Santos Susin
Xavier Cayla
Julien Guergnon
Angelita Rebollo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/FR2002/002705 external-priority patent/WO2003011898A2/fr
Priority claimed from FR0301014A external-priority patent/FR2850396B1/fr
Application filed by Pasteur Institut, Centre Nat Rech Scient, Agronomique Inst Nat Rech, Consejo Superior De Inverstiga, Univ Paris Vii, Univ Paris Curie, Alphonse Garcia, Frederic Dessauge, Veronique Hospital, Gordon Langsley, Santos Susin, Xavier Cayla, Julien Guergnon, Angelita Rebollo filed Critical Pasteur Institut
Priority to AU2003269055A priority Critical patent/AU2003269055A1/en
Publication of WO2004011595A2 publication Critical patent/WO2004011595A2/fr
Publication of WO2004011595A3 publication Critical patent/WO2004011595A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention se rapporte à de nouveaux vecteurs destinés qu transfert de protéines, d'acides nucléiques ou de toute autre molécule d'intérêt dans des cellules. Cette invention peut être appliquée à des domaines variés, notament pour la délivrance in vivo de médicaments dans des cellules cibles d'un organisme ou le transfert in vitro ou ex vivo de molécules d'intérêt dans des cellules en culture.
PCT/FR2003/002344 2002-07-26 2003-07-24 Vecteurs destines au transfert de molecules d'interet dans des cellules cibles WO2004011595A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003269055A AU2003269055A1 (en) 2002-07-26 2003-07-24 Vectors for transferring molecules of interest in target cells

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR02/02705 2002-03-04
PCT/FR2002/002705 WO2003011898A2 (fr) 2001-07-27 2002-07-26 Peptides synthetiques ou naturels liant la proteine phosphatase 2a, methode d'identification et utilisations
FR0301014A FR2850396B1 (fr) 2003-01-29 2003-01-29 Vecteurs destines au transfert de molecules d'interet dans des cellules cibles
FR03/01014 2003-01-29
US48276803P 2003-06-27 2003-06-27
US60/482,768 2003-06-27

Publications (2)

Publication Number Publication Date
WO2004011595A2 WO2004011595A2 (fr) 2004-02-05
WO2004011595A3 true WO2004011595A3 (fr) 2005-08-18

Family

ID=34841418

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2003/002344 WO2004011595A2 (fr) 2002-07-26 2003-07-24 Vecteurs destines au transfert de molecules d'interet dans des cellules cibles

Country Status (1)

Country Link
WO (1) WO2004011595A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022534A1 (fr) * 2005-08-19 2007-02-22 Propepgen Biostrategies, Inc. Preparation d'un compose peptidique (norapro-2002) et son utilisation dans l'activation d'enzymes proteines phosphatases-2a
US8129340B2 (en) 2006-09-08 2012-03-06 Institut Gustave Roussy Inhibitors of protein phosphatase 1, GADD34 and protein phosphatase 1/GADD34 complex, preparation and uses thereof
EP2236603A1 (fr) 2009-03-30 2010-10-06 Universite Pierre Et Marie Curie Peptides pro-apoptotiques
EP2621944A2 (fr) 2010-09-30 2013-08-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Peptides chimériques comprenant un peptide de pénétration et un domaine de liaison de la sous-unité catalytique de la pp2a à la capsase 9
WO2013098337A1 (fr) 2011-12-27 2013-07-04 Universite Pierre Et Marie Curie (Paris 6) Peptides de pénétration cellulaire
JP6169607B2 (ja) 2011-12-27 2017-07-26 ウニヴェルシテ ピエール エ マリー キュリー（パリ ６） 抗腫瘍アジュバント療法
CN103788211B (zh) * 2012-11-01 2017-09-01 中国科学院上海药物研究所 双功能肽、所述双功能肽与核酸分子形成的复合物以及***的药物组合物
FR3000746A1 (fr) * 2013-01-04 2014-07-11 Centre Nat Rech Scient Peptide pour son utilisation dans le traitement des neuronopathies motrices
EP2868326A1 (fr) 2013-11-04 2015-05-06 Université Pierre et Marie Curie (Paris 6) Peptides inhibiteurs de l'interaction TEAD/YAP-TAZ
CA3003156C (fr) 2015-11-06 2023-12-05 Terry Vanden Hoek Peptides et procede de traitement de l'arret cardiaque
US11174322B2 (en) 2017-07-24 2021-11-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Antibodies and peptides to treat HCMV related diseases
WO2023175022A1 (fr) 2022-03-16 2023-09-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Nouvelle méthode de traitement de maladies infectieuses

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996025945A1 (fr) * 1995-02-21 1996-08-29 Thomas Jefferson University ISOFORMES DE L'ENZYME HUMAINE DE CONVERSION DE L'INTERLEUKINE-1β ET LEURS PROCEDES D'UTILISATION
WO2000069900A2 (fr) * 1999-05-17 2000-11-23 Conjuchem, Inc. Protection de peptides therapeutiques endogenes contre l'activite peptidase par conjugaison de composants sanguins
WO2001015511A2 (fr) * 1999-09-01 2001-03-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Identification de peptides facilitant l'absorption et le transport cytoplasmique et/ou nucleaire de proteines, d'adn et de virus
WO2001053342A1 (fr) * 2000-01-21 2001-07-26 The Burnham Institute Peptides chimeres de ciblage de la prostate comportant une activite pro-apoptotique
FR2827866A1 (fr) * 2001-07-27 2003-01-31 Pasteur Institut Peptides synthetiques ou naturels liant la proteine phosphatase 2a, methode d'identification et utilisations

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996025945A1 (fr) * 1995-02-21 1996-08-29 Thomas Jefferson University ISOFORMES DE L'ENZYME HUMAINE DE CONVERSION DE L'INTERLEUKINE-1β ET LEURS PROCEDES D'UTILISATION
WO2000069900A2 (fr) * 1999-05-17 2000-11-23 Conjuchem, Inc. Protection de peptides therapeutiques endogenes contre l'activite peptidase par conjugaison de composants sanguins
WO2001015511A2 (fr) * 1999-09-01 2001-03-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Identification de peptides facilitant l'absorption et le transport cytoplasmique et/ou nucleaire de proteines, d'adn et de virus
WO2001053342A1 (fr) * 2000-01-21 2001-07-26 The Burnham Institute Peptides chimeres de ciblage de la prostate comportant une activite pro-apoptotique
FR2827866A1 (fr) * 2001-07-27 2003-01-31 Pasteur Institut Peptides synthetiques ou naturels liant la proteine phosphatase 2a, methode d'identification et utilisations

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CARTUS T ET AL: "Distribution of protein phosphatases type 1 and 2A in RINm5F cells", REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, NL, vol. 77, no. 1-3, 16 October 1998 (1998-10-16), pages 77 - 81, XP002255404, ISSN: 0167-0115 *
HERICHE J-K ET AL: "Regulation of protein phosphatase 2A by direct interaction with casein kinase 2-alpha", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 276, no. 5314, 1997, pages 952 - 955, XP002255403, ISSN: 0036-8075 *
SARNO S ET AL: "A multifunctional network of basic residues confers unique properties to protein kinase CK2", MOLECULAR AND CELLULAR BIOCHEMISTRY, NORWELL, MA, US, vol. 191, no. 1/2, January 1999 (1999-01-01), pages 13 - 19, XP008022415, ISSN: 0300-8177 *
SHERMAN M P ET AL: "Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 75, no. 3, February 2001 (2001-02-01), pages 1522 - 1532, XP002966101, ISSN: 0022-538X *
SUZUKI T ET AL: "Possible existence of common internalization mechanisms among arginine-rich peptides", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 277, no. 4, 25 January 2002 (2002-01-25), pages 2437 - 2443, XP002963938, ISSN: 0021-9258 *

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Publication number Publication date
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