WO2004011365A3 - Micro-channel design features that facilitate centripetal fluid transfer - Google Patents

Micro-channel design features that facilitate centripetal fluid transfer Download PDF

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Publication number
WO2004011365A3
WO2004011365A3 PCT/US2003/022226 US0322226W WO2004011365A3 WO 2004011365 A3 WO2004011365 A3 WO 2004011365A3 US 0322226 W US0322226 W US 0322226W WO 2004011365 A3 WO2004011365 A3 WO 2004011365A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid transfer
features
micro
channel design
facilitate
Prior art date
Application number
PCT/US2003/022226
Other languages
French (fr)
Other versions
WO2004011365A2 (en
Inventor
Sean M Desmond
John Shigeura
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/336,706 external-priority patent/US7214348B2/en
Priority claimed from US10/336,274 external-priority patent/US7198759B2/en
Application filed by Applera Corp filed Critical Applera Corp
Priority to JP2005505600A priority Critical patent/JP2005533651A/en
Priority to EP03771636A priority patent/EP1534429A4/en
Priority to AU2003253944A priority patent/AU2003253944A1/en
Priority to CA002493700A priority patent/CA2493700A1/en
Publication of WO2004011365A2 publication Critical patent/WO2004011365A2/en
Publication of WO2004011365A3 publication Critical patent/WO2004011365A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Microfluidic device (100) is formed in substrate (108) and can include input port (106) in fluid communication with input channel (104) connected to feed channel (110). The microfluidic devices have a plurality of specialized processing features that facilitate centripetal fluid transfer is also provided.
PCT/US2003/022226 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer WO2004011365A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2005505600A JP2005533651A (en) 2002-07-26 2003-07-16 Microchannel design features that facilitate fluid movement by centripetal force
EP03771636A EP1534429A4 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer
AU2003253944A AU2003253944A1 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer
CA002493700A CA2493700A1 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US39885102P 2002-07-26 2002-07-26
US60/398,851 2002-07-26
US39954802P 2002-07-30 2002-07-30
US60/399,548 2002-07-30
US36633003A 2003-01-03 2003-01-03
US10/336,706 US7214348B2 (en) 2002-07-26 2003-01-03 Microfluidic size-exclusion devices, systems, and methods
US10/366,330 2003-01-03
US10/336,274 2003-01-03
US10/336,274 US7198759B2 (en) 2002-07-26 2003-01-03 Microfluidic devices, methods, and systems
US10/336,706 2003-01-03

Publications (2)

Publication Number Publication Date
WO2004011365A2 WO2004011365A2 (en) 2004-02-05
WO2004011365A3 true WO2004011365A3 (en) 2004-06-10

Family

ID=31192473

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/022226 WO2004011365A2 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer

Country Status (5)

Country Link
EP (1) EP1534429A4 (en)
JP (1) JP2005533651A (en)
AU (1) AU2003253944A1 (en)
CA (1) CA2493700A1 (en)
WO (1) WO2004011365A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6720187B2 (en) 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
JP5131538B2 (en) * 2008-05-07 2013-01-30 セイコーエプソン株式会社 Reaction liquid filling method
JP5298718B2 (en) * 2008-09-12 2013-09-25 セイコーエプソン株式会社 Centrifugal device for filling biological sample reaction chip with reaction solution
CN101533005B (en) * 2009-04-14 2012-10-10 北京大学 Microflow distribution device, manufacturing method and application thereof
BR112013027990B1 (en) 2011-05-18 2020-11-03 Diasorin S.P.A. valve structure in a sample processing device and method for operating valves in a sample processing device
JP2015031643A (en) * 2013-08-06 2015-02-16 ブラザー工業株式会社 Inspection chip

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037499A1 (en) * 2000-06-05 2002-03-28 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69533554T2 (en) * 1994-11-10 2005-01-27 Orchid Biosciences, Inc. LIQUID DISTRIBUTION SYSTEM
KR100306951B1 (en) * 1995-12-05 2001-11-15 테칸 보스턴, 인코포레이티드 Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
EP1092144A1 (en) * 1998-06-29 2001-04-18 Evotec BioSystems AG Method and device for manipulating particles in microsystems
US6296020B1 (en) * 1998-10-13 2001-10-02 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
WO2000031602A1 (en) * 1998-11-20 2000-06-02 Sepiatec Gmbh Method and device for regulating individual sub-flows of a system for conveying fluid media
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
US6395232B1 (en) * 1999-07-09 2002-05-28 Orchid Biosciences, Inc. Fluid delivery system for a microfluidic device using a pressure pulse
EP1284819A2 (en) * 2000-05-15 2003-02-26 Tecan Trading AG Microfluidics devices and methods for high throughput screening
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
CA2439627A1 (en) * 2001-03-19 2002-09-26 Gyros Ab Structural units that define fluidic functions
AU2002213115A1 (en) * 2001-04-13 2002-10-28 Nanostream, Inc. Microfluidic metering systems and methods
US6845787B2 (en) * 2002-02-23 2005-01-25 Nanostream, Inc. Microfluidic multi-splitter

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US20020037499A1 (en) * 2000-06-05 2002-03-28 California Institute Of Technology Integrated active flux microfluidic devices and methods

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Also Published As

Publication number Publication date
EP1534429A2 (en) 2005-06-01
CA2493700A1 (en) 2004-02-05
WO2004011365A2 (en) 2004-02-05
JP2005533651A (en) 2005-11-10
EP1534429A4 (en) 2005-09-07
AU2003253944A1 (en) 2004-02-16

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