WO2004011143A3 - One-directional microball valve for a microfluidic device - Google Patents

One-directional microball valve for a microfluidic device Download PDF

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Publication number
WO2004011143A3
WO2004011143A3 PCT/US2003/022470 US0322470W WO2004011143A3 WO 2004011143 A3 WO2004011143 A3 WO 2004011143A3 US 0322470 W US0322470 W US 0322470W WO 2004011143 A3 WO2004011143 A3 WO 2004011143A3
Authority
WO
WIPO (PCT)
Prior art keywords
microfluidic device
directional
valve
microball
microball valve
Prior art date
Application number
PCT/US2003/022470
Other languages
French (fr)
Other versions
WO2004011143A2 (en
Inventor
David M Cox
Michael P Harrold
Dennis E Mead
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/403,652 external-priority patent/US7135147B2/en
Priority claimed from US10/403,640 external-priority patent/US7201881B2/en
Priority claimed from US10/414,179 external-priority patent/US20040018559A1/en
Priority claimed from US10/426,587 external-priority patent/US6817373B2/en
Application filed by Applera Corp filed Critical Applera Corp
Priority to CA002488997A priority Critical patent/CA2488997A1/en
Priority to AU2003253998A priority patent/AU2003253998A1/en
Priority to EP03771653A priority patent/EP1534982A4/en
Priority to JP2004524639A priority patent/JP2006511762A/en
Publication of WO2004011143A2 publication Critical patent/WO2004011143A2/en
Publication of WO2004011143A3 publication Critical patent/WO2004011143A3/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
    • F15C5/00—Manufacture of fluid circuit elements; Manufacture of assemblages of such elements integrated circuits
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/02—Check valves with guided rigid valve members
    • F16K15/04—Check valves with guided rigid valve members shaped as balls
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0023—Constructional types of microvalves; Details of the cutting-off member with ball-shaped valve members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
    • F16K99/0057—Operating means specially adapted for microvalves actuated by fluids the fluid being the circulating fluid itself, e.g. check valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/008—Multi-layer fabrications

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Hardware Design (AREA)
  • Fluid Mechanics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)
  • Taps Or Cocks (AREA)
  • Fluid-Driven Valves (AREA)
  • Check Valves (AREA)

Abstract

A microfluidic device that includes a micro ball valve is provided. The microball valve is capable of preventing or interrupting fluid flow through the microfluidic device. The microfluidic device can include a substrate layer, and a microfluidic pathway that includes the microball valve. Methods are provided for manipulating fluids using the microfluidic device.
PCT/US2003/022470 2002-07-26 2003-07-17 One-directional microball valve for a microfluidic device WO2004011143A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002488997A CA2488997A1 (en) 2002-07-26 2003-07-17 One-directional microball valve for a microfluidic device
AU2003253998A AU2003253998A1 (en) 2002-07-26 2003-07-17 One-directional microball valve for a microfluidic device
EP03771653A EP1534982A4 (en) 2002-07-26 2003-07-17 One-directional microball valve for a microfluidic device
JP2004524639A JP2006511762A (en) 2002-07-26 2003-07-17 Unidirectional microball valve for microfluidic devices

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US39885202P 2002-07-26 2002-07-26
US39894602P 2002-07-26 2002-07-26
US39877702P 2002-07-26 2002-07-26
US39877802P 2002-07-26 2002-07-26
US60/398,852 2002-07-26
US60/398,778 2002-07-26
US60/398,946 2002-07-26
US60/398,777 2002-07-26
US10/403,652 US7135147B2 (en) 2002-07-26 2003-03-31 Closing blade for deformable valve in a microfluidic device and method
US10/403,640 2003-03-31
US10/403,652 2003-03-31
US10/403,640 US7201881B2 (en) 2002-07-26 2003-03-31 Actuator for deformable valves in a microfluidic device, and method
US10/414,179 US20040018559A1 (en) 2002-07-26 2003-04-14 Size-exclusion ion-exchange particles
US10/414,179 2003-04-14
US10/426,587 2003-04-30
US10/426,587 US6817373B2 (en) 2002-07-26 2003-04-30 One-directional microball valve for a microfluidic device

Publications (2)

Publication Number Publication Date
WO2004011143A2 WO2004011143A2 (en) 2004-02-05
WO2004011143A3 true WO2004011143A3 (en) 2004-09-16

Family

ID=31192598

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/022470 WO2004011143A2 (en) 2002-07-26 2003-07-17 One-directional microball valve for a microfluidic device

Country Status (5)

Country Link
EP (1) EP1534982A4 (en)
JP (1) JP2006511762A (en)
AU (1) AU2003253998A1 (en)
CA (1) CA2488997A1 (en)
WO (1) WO2004011143A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939018B2 (en) 2000-06-28 2011-05-10 3M Innovative Properties Company Multi-format sample processing devices and systems
US8003051B2 (en) 2001-12-28 2011-08-23 3M Innovative Properties Company Thermal structure for sample processing systems
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US7032608B2 (en) * 2004-09-01 2006-04-25 Harris Corporation Microfluidic check-valve embedded in LCP
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
EP2049283B1 (en) * 2006-08-10 2015-02-18 California Institute of Technology Microfluidic valve having free-floating member and method of fabrication
WO2012037348A2 (en) 2010-09-15 2012-03-22 Minipumps, Llc Molded and packaged elastomeric check valve
CN103501908B (en) 2011-05-18 2016-03-16 3M创新有限公司 The system and method that valve is adjusted on sample processing device
AU2014205179B2 (en) 2013-01-11 2018-08-09 Minipumps, Llc Diaphragm check valves and methods of manufacture thereof
WO2017047032A1 (en) * 2015-09-14 2017-03-23 パナソニックＩｐマネジメント株式会社 Micro check valve apparatus
WO2018183744A1 (en) 2017-03-29 2018-10-04 The Research Foundation For The State University Of New York Microfluidic device and methods
CN118086053B (en) * 2024-04-29 2024-07-09 四川迪亚生物科技集团有限公司 Self-perfusion culture plate and use method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911616A (en) * 1988-01-19 1990-03-27 Laumann Jr Carl W Micro miniature implantable pump
US6595950B1 (en) * 2000-05-11 2003-07-22 Zevex, Inc. Apparatus and method for preventing free flow in an infusion line
US20030152463A1 (en) * 2001-12-21 2003-08-14 Michael Shuler Self priming micropump

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US398851A (en) 1889-03-05 Berge
US399548A (en) 1889-03-12 nageldinger
KR100552078B1 (en) * 2001-05-31 2006-02-20 유재천 A micro valve apparatus using micro bead and method for controlling the same
US6739576B2 (en) * 2001-12-20 2004-05-25 Nanostream, Inc. Microfluidic flow control device with floating element

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911616A (en) * 1988-01-19 1990-03-27 Laumann Jr Carl W Micro miniature implantable pump
US6595950B1 (en) * 2000-05-11 2003-07-22 Zevex, Inc. Apparatus and method for preventing free flow in an infusion line
US20030152463A1 (en) * 2001-12-21 2003-08-14 Michael Shuler Self priming micropump

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1534982A4 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939018B2 (en) 2000-06-28 2011-05-10 3M Innovative Properties Company Multi-format sample processing devices and systems
US8003051B2 (en) 2001-12-28 2011-08-23 3M Innovative Properties Company Thermal structure for sample processing systems
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Also Published As

Publication number Publication date
EP1534982A2 (en) 2005-06-01
WO2004011143A2 (en) 2004-02-05
JP2006511762A (en) 2006-04-06
CA2488997A1 (en) 2004-02-05
EP1534982A4 (en) 2006-02-08
AU2003253998A1 (en) 2004-02-16

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