WO2003104390A3 - Adamts nucleic acids and proteins - Google Patents

Adamts nucleic acids and proteins Download PDF

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Publication number
WO2003104390A3
WO2003104390A3 PCT/US2002/018221 US0218221W WO03104390A3 WO 2003104390 A3 WO2003104390 A3 WO 2003104390A3 US 0218221 W US0218221 W US 0218221W WO 03104390 A3 WO03104390 A3 WO 03104390A3
Authority
WO
WIPO (PCT)
Prior art keywords
adamts
proteins
nucleic acids
adamts3
homologs
Prior art date
Application number
PCT/US2002/018221
Other languages
French (fr)
Other versions
WO2003104390A2 (en
Inventor
Suneel Apte
Satoshi Hirohata
David Eyre
Russel Fernandes
Original Assignee
Cleveland Clinic Foundation
Suneel Apte
Satoshi Hirohata
David Eyre
Russel Fernandes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cleveland Clinic Foundation, Suneel Apte, Satoshi Hirohata, David Eyre, Russel Fernandes filed Critical Cleveland Clinic Foundation
Priority to AU2002314999A priority Critical patent/AU2002314999A1/en
Publication of WO2003104390A2 publication Critical patent/WO2003104390A2/en
Publication of WO2003104390A3 publication Critical patent/WO2003104390A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention is directed to ADAMTS3 and the corresponding protein ADAMTS-3 as well as variants, homologs, and equivalents, and their use in procollagen processing.
PCT/US2002/018221 2002-06-06 2002-06-06 Adamts nucleic acids and proteins WO2003104390A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002314999A AU2002314999A1 (en) 2002-06-06 2002-06-06 Adamts nucleic acids and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29638402P 2002-06-06 2002-06-06
US60/296,384 2002-06-06

Publications (2)

Publication Number Publication Date
WO2003104390A2 WO2003104390A2 (en) 2003-12-18
WO2003104390A3 true WO2003104390A3 (en) 2004-06-10

Family

ID=29735802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/018221 WO2003104390A2 (en) 2002-06-06 2002-06-06 Adamts nucleic acids and proteins

Country Status (2)

Country Link
AU (1) AU2002314999A1 (en)
WO (1) WO2003104390A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053774A2 (en) * 1999-03-08 2000-09-14 Neurocrine Biosciences, Inc. Metalloproteinases and methods of use therefor
JP2001017183A (en) * 1999-07-09 2001-01-23 Yamanouchi Pharmaceut Co Ltd New metal protease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053774A2 (en) * 1999-03-08 2000-09-14 Neurocrine Biosciences, Inc. Metalloproteinases and methods of use therefor
JP2001017183A (en) * 1999-07-09 2001-01-23 Yamanouchi Pharmaceut Co Ltd New metal protease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FERANDES R. J. ET AL.: "Procollagen II amino propeptide processing by ADMTS-3", J. BIOL. CHEM., vol. 276, 24 August 2001 (2001-08-24), pages 31502 - 31509 *
NAGASE T. ET AL.: "Prediction of the encoding sequences of unidentified human genes VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro", DNA RES., vol. 4, no. 2, 1997, pages 141 - 150 *

Also Published As

Publication number Publication date
AU2002314999A8 (en) 2003-12-22
WO2003104390A2 (en) 2003-12-18
AU2002314999A1 (en) 2003-12-22

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