WO2003089469A3 - Cation channel proteins - Google Patents

Cation channel proteins Download PDF

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Publication number
WO2003089469A3
WO2003089469A3 PCT/GB2003/001655 GB0301655W WO03089469A3 WO 2003089469 A3 WO2003089469 A3 WO 2003089469A3 GB 0301655 W GB0301655 W GB 0301655W WO 03089469 A3 WO03089469 A3 WO 03089469A3
Authority
WO
WIPO (PCT)
Prior art keywords
cation channel
channel proteins
proteins
inpionch04
inpionch03
Prior art date
Application number
PCT/GB2003/001655
Other languages
French (fr)
Other versions
WO2003089469A2 (en
Inventor
Anna Elizabeth Lobley
David Michalovich
Kathryn Elizabeth Allen
Lindsey Reynolds
Valerie Nathalie Pierron
Janet Marjorie Allen
Original Assignee
Inpharmatica Ltd
Anna Elizabeth Lobley
David Michalovich
Kathryn Elizabeth Allen
Lindsey Reynolds
Valerie Nathalie Pierron
Janet Marjorie Allen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inpharmatica Ltd, Anna Elizabeth Lobley, David Michalovich, Kathryn Elizabeth Allen, Lindsey Reynolds, Valerie Nathalie Pierron, Janet Marjorie Allen filed Critical Inpharmatica Ltd
Priority to AU2003232308A priority Critical patent/AU2003232308A1/en
Publication of WO2003089469A2 publication Critical patent/WO2003089469A2/en
Publication of WO2003089469A3 publication Critical patent/WO2003089469A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This invention relates to novel proteins, termed INPIONCH03 and INPIONCH04, herein identified as members of the PKD/REJ family of cation channels and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
PCT/GB2003/001655 2002-04-16 2003-04-16 Cation channel proteins WO2003089469A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003232308A AU2003232308A1 (en) 2002-04-16 2003-04-16 Cation channel proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0208707.0 2002-04-16
GB0208707A GB0208707D0 (en) 2002-04-16 2002-04-16 Proteins

Publications (2)

Publication Number Publication Date
WO2003089469A2 WO2003089469A2 (en) 2003-10-30
WO2003089469A3 true WO2003089469A3 (en) 2004-01-08

Family

ID=9934937

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/001655 WO2003089469A2 (en) 2002-04-16 2003-04-16 Cation channel proteins

Country Status (3)

Country Link
AU (1) AU2003232308A1 (en)
GB (1) GB0208707D0 (en)
WO (1) WO2003089469A2 (en)

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 15 September 2001 (2001-09-15), NAGASE T ET AL: "Homo sapiens mRNA for KIAA1879 protein, partial cds.", XP002249170, accession no. NCBI Database accession no. AB067466 *
DATABASE GENBANK [online] 2 November 2001 (2001-11-02), DOE JOINT GENOME INSTITUTE: "Homo sapiens chromosome 16 clone RP11-303E16, complete sequence", XP002249169, accession no. NCBI Database accession no. AC092718 *
DATABASE GENBANK [online] 7 February 2002 (2002-02-07), NCBI ANNOTATION PROJECT.: "Homo sapiens chromosome 16 working draft sequence segment.", XP002249173, accession no. NCBI Database accession no. NT_024792 *
DATABASE GENBANK [online] 7 February 2002 (2002-02-07), NCBI ANNOTATION PROJECT.: "Homo sapiens similar to KIAA1879 protein (LOC162163), mRNA.", XP002249172, accession no. NCBI Database accession no. XM_091397 *
DATABASE GENBANK [online] 7 February 2002 (2002-02-07), NCBI ANNOTATION PROJECT: "KIAA1879 protein [Homo sapiens]", XP002249171, accession no. NCBI Database accession no. XP_056635 *
HUGHES J ET AL: "Identification of a human homologue of the sea urchin receptor for egg jelly: a polycystic kidney disease-like protein", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 8, no. 3, March 1999 (1999-03-01), pages 543 - 549, XP002120871, ISSN: 0964-6906 *
LI AIRONG ET AL: "Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes.", GENOMICS. UNITED STATES JUN 2003, vol. 81, no. 6, June 2003 (2003-06-01), pages 596 - 608, XP002249168, ISSN: 0888-7543 *
MENGERINK KATHRYN J ET AL: "suREJ3, a polycystin-1 protein, is cleaved at the GPS domain and localizes to the acrosomal region of sea urchin sperm.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 2, 11 January 2002 (2002-01-11), January 11, 2002, pages 943 - 948, XP002249167, ISSN: 0021-9258 *
NAGASE T ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES XXI. THE COMPLETE SEQUENCES OF 60 NEW CDNA CLONES FROM BRAIN WHICH CODE FOR LARGE PROTEINS", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 8, no. 4, 31 August 2001 (2001-08-31), pages 179 - 187, XP001055485, ISSN: 1340-2838 *
STAYNER C ET AL: "Polycystin channels and kidney disease", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, vol. 22, no. 11, 1 November 2001 (2001-11-01), pages 543 - 546, XP004320222, ISSN: 0165-6147 *

Also Published As

Publication number Publication date
GB0208707D0 (en) 2002-05-29
WO2003089469A2 (en) 2003-10-30
AU2003232308A1 (en) 2003-11-03
AU2003232308A8 (en) 2003-11-03

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