WO2003087309A3 - Bdnf polymorphisms and association with bipolar disorder - Google Patents

Bdnf polymorphisms and association with bipolar disorder Download PDF

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Publication number
WO2003087309A3
WO2003087309A3 PCT/US2003/010527 US0310527W WO03087309A3 WO 2003087309 A3 WO2003087309 A3 WO 2003087309A3 US 0310527 W US0310527 W US 0310527W WO 03087309 A3 WO03087309 A3 WO 03087309A3
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WO
WIPO (PCT)
Prior art keywords
bipolar disorder
association
bdnf
polymorphisms
neuropsychiatric disorders
Prior art date
Application number
PCT/US2003/010527
Other languages
French (fr)
Other versions
WO2003087309A2 (en
Inventor
Pamela Sklar
Eric S Lander
Melvin G Mcinnis
J Raymond Depaulo Jr
Original Assignee
Whitehead Biomedical Inst
Gen Hospital Corp
Univ Johns Hopkins
Pamela Sklar
Eric S Lander
Melvin G Mcinnis
J Raymond Depaulo Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitehead Biomedical Inst, Gen Hospital Corp, Univ Johns Hopkins, Pamela Sklar, Eric S Lander, Melvin G Mcinnis, J Raymond Depaulo Jr filed Critical Whitehead Biomedical Inst
Priority to AU2003223486A priority Critical patent/AU2003223486A1/en
Publication of WO2003087309A2 publication Critical patent/WO2003087309A2/en
Publication of WO2003087309A3 publication Critical patent/WO2003087309A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Methods for diagnosing and treating neuropsychiatric disorders, especially bipolar disorder, and to methods for identifying compounds for use in the diagnosis and treatment of neuropsychiatric disorders are disclosed. Also disclosed are novel compounds and pharmaceutical compositions for use in the diagnosis and treatment of neuropsychiatric disorders such as bipolar disorder.
PCT/US2003/010527 2002-04-08 2003-04-07 Bdnf polymorphisms and association with bipolar disorder WO2003087309A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003223486A AU2003223486A1 (en) 2002-04-08 2003-04-07 Bdnf polymorphisms and association with bipolar disorder

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37126002P 2002-04-08 2002-04-08
US60/371,260 2002-04-08

Publications (2)

Publication Number Publication Date
WO2003087309A2 WO2003087309A2 (en) 2003-10-23
WO2003087309A3 true WO2003087309A3 (en) 2004-07-08

Family

ID=29250662

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/010527 WO2003087309A2 (en) 2002-04-08 2003-04-07 Bdnf polymorphisms and association with bipolar disorder

Country Status (2)

Country Link
AU (1) AU2003223486A1 (en)
WO (1) WO2003087309A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VENTRIGLIA, M. ET AL.: "Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease", MOLECULAR PSYCHIATRY, vol. 7, 2002, pages 136 - 137, XP002977279 *

Also Published As

Publication number Publication date
WO2003087309A2 (en) 2003-10-23
AU2003223486A8 (en) 2003-10-27
AU2003223486A1 (en) 2003-10-27

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