WO2003024348A1 - Polypectomy device and method - Google Patents
Polypectomy device and method Download PDFInfo
- Publication number
- WO2003024348A1 WO2003024348A1 PCT/US2002/023833 US0223833W WO03024348A1 WO 2003024348 A1 WO2003024348 A1 WO 2003024348A1 US 0223833 W US0223833 W US 0223833W WO 03024348 A1 WO03024348 A1 WO 03024348A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- jaw
- catheter
- distal end
- cable
- proximal end
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/32056—Surgical snare instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/08—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
- A61B18/082—Probes or electrodes therefor
- A61B18/085—Forceps, scissors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/08—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
- A61B18/10—Power sources therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/2812—Surgical forceps with a single pivotal connection
- A61B17/282—Jaws
- A61B2017/2825—Inserts of different material in jaws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00321—Head or parts thereof
- A61B2018/00327—Ear, nose or throat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00482—Digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1407—Loop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1407—Loop
- A61B2018/141—Snare
Definitions
- the invention relates general to medical devices, and more specifically to devices for performing a polypectomy.
- Polyps are defined as any growth or mass protruding from a mucous membrane. Polyps can occur wherever there is mucous membrane, namely, in the nose, ears, mouth, lungs, heart, stomach, intestines, urinary bladder, uterus, and cervix. Most polyps are benign growths that eventually stop growing. But some of these polyps keep growing. Genetic mutations can transform them into cancerous tumors. As these cancerous tumors grow larger, they continue growing and begin to burrow deeper and deeper into the tissue supporting the polyp. In the final stages the cancer invades the blood and lymph systems and the malignant cells of the tumor spread to other organs. The problem is particularly severe, yet readily treated, in the colon.
- Colorectal cancer is the second leading cause of death due to cancer in the United States. If the cancer is detected and treated in its early stages, it can be cured more than 90% of the time. Thus, early detection and removal of colorectal polyps, whether benign, pre-cancerous, or cancerous, is highly effective in avoiding or treating colorectal cancer.
- Polyps may be attached to a mucous membrane by a thin stalk or the polyp may have a broad base.
- a polyp that is attached by a thin stalk is called a pedunculated polyp and a polyp that is attached by a broad base is called a sessile polyp.
- Various devices have been proposed for removing polyps, especially pedunculated polyps, from the body. For example, Avellanet, Polypectomy Snare Instrument, U.S. Patent 6,015,415 (Jan. 18, 2000) teaches a polypectomy device using a snare loop connected to a power source to supply cautery current.
- the snare loop is used to capture the polyp and current is applied to the snare loop which cauterizes the polyp as the snare is closed tightly around the polyp.
- McKeating, Polypectomy Instrument, U.S. Patent 5,746,747 (May 5, 1998) teaches a polypectomy device using grasping forceps to hold the polyp and a snare wire for cutting the polyp. Electrical current is supplied to the snare wire to cut and cauterize the polyp while the grasping forceps hold onto the body of the polyp.
- Nakao et al . Surgical Cauterization Snare with Ligating Suture, U.S. Patent 5,906,620 (May 25, 1999) teaches using two snare loops. The first loop cauterizes the polyp while the second loop acts as a suture for ligating the polyp. The second loop is left behind in the colon.
- the present polypectomy device and method effectively removes polyps from the body.
- the device includes a first jaw and a second jaw.
- One of the jaws includes a heating element for cauterizing the tissue of the polyp.
- a snare cable is routed through each of the jaws.
- the snare cable forms a hoop for capturing the polyp.
- the closing of the jaws works in conjunction with a heating element to cut and seal the tissue between the jaws.
- Figure 1 is an overview of the polypectomy device inserted into the colon of a patient.
- Figure 2 is an overall side-view of the polypectomy device with a handle, an electrical connector, and a jaw assembly.
- Figure 3 is a close-up cross sectional view of the jaw assembly located on the distal end of the polypectomy device.
- Figure 4 is an overview of the polypectomy device inserted into a sinus of a patient with the snare wire encircling the base of the polyp.
- Figure 5 is a like view with the snare wire pulled proximally to align the jaws of the polypectomy device.
- Figure 6 is an overview of the polypectomy device inserted into the uterus of a patient with the snare wire encircling the base of the polyp.
- FIG. 1 shows an overview of the polypectomy device inserted into the colon of a patient 1.
- the polypectomy device 2 includes an elongated flexible catheter 3 extending out of the distal end of an endoscope 4.
- the distal end of the catheter includes a fixed jaw 5, a moveable jaw 6, and a snare cable 7.
- the snare cable may be operated to capture the polyp 8 and as the length of the snare cable is shortened, the polyp is drawn into the jaws and the moveable jaw is pulled toward the fixed jaw.
- the heating element 17 on the fixed jaw See Figures 2 and 3 may be operated to necrose the tissue trapped between the jaws. The combination of heat and pressure causes the tissue to divide which severs the polyp from the colon wall 9 of the colon 10.
- Figure 2 shows an overall side-view of the polypectomy device 2.
- the proximal end of the device includes a two-wire electrical connector 12, and a handle 13.
- the two-wire electrical connector connects the catheter 3 to an electrical power source (not shown) .
- the handle includes a cable trigger 14 and a fixed finger hold 15.
- the cable trigger may be operated to pull the snare cable 7, which captures the polyp and operates the moveable jaw 6. Closing the jaw assembly and activating the power source to heat the heating element 17 cuts the polyp and seals the tissue.
- Figure 3 is a close-up cross sectional view of the distal end of the polypectomy device.
- the snare cable 7, the fixed jaw 5 and the moveable jaw 6 extend out of the distal end of the catheter body 3.
- the fixed jaw is attached to the catheter body, and the moveable jaw is operatively connected to the catheter body at a hinge 16. It should be noted that while we have referred to a fixed jaw and a moveable jaw, both jaws may be moveable. Both jaws may be hinged to the catheter, or otherwise rotatable relative to each other and secured to the catheter.
- the fixed jaw 5 includes a heating element 17, an insulation tube 18, and a lumen 19.
- the moveable jaw 6 includes a hole 20 (through which the snare cable passes) at its distal tip, a hinge 16 at its proximal end, and a silicone pad 21.
- a distal outlet 22 is formed by the lumen 19 of the fixed jaw extending completely through the fixed jaw.
- the fixed jaw and the moveable jaw close together in a scissor- like movement.
- the surfaces of the fixed jaw and the moveable jaw that fit together are the grasping faces.
- the silicone pad 21 of the moveable jaw is located along the grasping face of the moveable jaw and the portion of the insulation tube 18 facing the moveable jaw serves as the grasping face of the fixed jaw.
- the fixed jaw and the moveable jaw can be composed of stainless steel or other suitable metal, plastic, or ceramic.
- the fixed jaw also includes an insulation tube that can be composed of polyamide, fluropolymer, or a PTFE/polyamide blend such as Xylan® (other insulative materials can be used) .
- the insulation tube 18 isolates the heating element 17 from the stainless steel portion of the fixed jaw thereby preventing the heating element from heating the entire fixed jaw.
- the heating element is composed of an electrically conductive material, such as nichrome, which is sufficiently resistive to heat up significantly when electricity is passed through it.
- the heating element can be approximately 1/10,000 nicrome wire having a length of approximately 10 mm.
- the power supply can generate approximately 3 to 30 watts of power, and the heating element approximately 2 to 7 watts of power.
- Alternative forms of heating elements may be used, such as ceramic heating elements, RF heating elements, and onopolar and bipolar heating elements. Additionally, heating • elements may be placed on either jaw, or on both jaws.
- the distal end of the snare cable 7 is fixed to the catheter body 3 and extends along the outside of the moveable jaw 6 through the hole 20 in the distal tip of the moveable jaw (though it may be fixed, at its terminus, to the distal tip of the moveable jaw) .
- the cable then goes into the distal outlet 22 of the fixed jaw 5, through the lumen 19 to the cable trigger 14 located at the proximal end of the device.
- the lumen 19 of the fixed jaw includes a friction liner 23.
- the friction liner can be composed of nylon or Teflon®, which reduces the friction created by the snare cable 7 moving through the lumen of the fixed jaw, thereby permitting the snare cable to be operated smoothly and easily.
- the fixed jaw 5 is formed as a cylindrical tube and the moveable jaw 6 is formed as a concave semicylindrical body that mates with the fixed jaw.
- the fixed jaw and the moveable jaw are fashioned similar to a curling iron for hair, which includes a cylindrical heated tube and a moveable semicylindrical jaw that fit together to curl hair.
- the fixed jaw is called the barrel and the moveable jaw is called the clip, and they function in a similar manner as the fixed jaw and the moveable jaw in this device.
- the fixed jaw may be referred to as a barrel
- the moveable jaw may be referred to as a clip.
- the outer most layer of the catheter body is an insulated catheter jacket 24.
- the electrical wire is connected to the distal end of the heating element 17, which is located on the grasping face of the fixed jaw, and supplies the electrical current from the electric source to the heating element.
- the current flows from the electric power source into the two-wire electrical connector 12 through the electrical wire 25 into the heating element 17.
- the current then flows from the heating element through the conductive crimp 27 , located at the proximal end of the heating element, into the braided conductor 26 and back to the two-wire connector to complete the circuit.
- the braided conductor may be replaced with a wire if space permits.
- an endoscope is inserted into the patient's body to the area where the polyp is located.
- the endoscope is used to view inside the patient's body and look for polyps. If a polyp is found the surgeon inserts the polypectomy catheter into the working lumen of the endoscope. The surgeon then moves the distal end of the catheter toward the polyp and extends the snare cable to form a hoop which enables the surgeon to capture the polyp.
- the surgeon manually rotates the catheter such that the snare cable hoop can be properly oriented and placed over the polyp. The manual rotation of the catheter is accomplished by rotation of the handle.
- the surgeon activates the cable trigger thereby drawing the snare cable proximally relative to the catheter and closing the loop about the polyp.
- the fixed jaw and the moveable jaw are pulled into place on either side of the polyp.
- the surgeon further shortens the snare cable, it operates the moveable jaw to draw it toward the fixed jaw, thereby pulling the jaws together.
- the electrical power source is activated, which heats the heating element located on the fixed jaw. Therefore, as the jaws are held closed, the heating element and the jaws work together to both cut and seal the tissue.
- the power source may be activated by a footswitch (not shown) , or it may be operated by a switch or button located on the catheter or the power source . It may also be activated by a limit switch which is activated by the proximal movement of the cable trigger.
- polyps form in mucous membrane, and mucous membranes exist in many areas of the body.
- Polyps can form in a patient's colon 10.
- One way of looking for polyps in a patient's colon is a colonoscopy.
- the surgeon inserts an endoscope 4 into the patient's colon through the patient's anus 28 (See Figure 1) . If a polyp 8 is found, the surgeon inserts the polypectomy device 2 into the working lumen of the endoscope and follows the procedure discussed above.
- polyps formed in the nasal sinuses can be removed with the device.
- An endoscope 4 is inserted into the patient's nasal sinuses 29, through the patient's nostril 30.
- the polypectomy device 2 is inserted into the endoscope .
- the snare cable 7 extends to form a hoop which enables the surgeon to capture the polyp.
- the surgeon activates the cable trigger 14 thereby drawing the snare cable proximally.
- the fixed jaw 5 and the moveable jaw 6 are pulled into place on either side of the polyp 8.
- the surgeon As the surgeon further pulls the snare cable, it operates the moveable jaw to draw it toward the fixed jaw, thereby mating the jaws together, or at least bring the jaws into apposition with the polyp stalk caught between them.
- the electrical power source With the activation of the moveable jaw, the electrical power source is activated, which heats the heating element located on the fixed jaw.
- the power source is activated by a footswitch (not shown) .
- polyps in a patient's uterus can be removed with the device. Again, a like procedure is followed.
- An endoscope 4 is inserted into the patient's uterus 31 through the vagina 32. If a polyp 8 is found, the surgeon inserts the polypectomy device 2 into the working lumen of the endoscope and follows the procedure discussed above .
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02798909A EP1416870A4 (en) | 2001-07-27 | 2002-07-26 | Polypectomy device and method |
JP2003528248A JP2005502423A (en) | 2001-07-27 | 2002-07-26 | Apparatus and method for polypectomy |
CA002454354A CA2454354A1 (en) | 2001-07-27 | 2002-07-26 | Polypectomy device and method |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/916,356 | 2001-07-27 | ||
US09/916,356 US6616654B2 (en) | 2001-07-27 | 2001-07-27 | Polypectomy device and method |
US09/917,104 | 2001-07-27 | ||
US09/917,104 US6616659B1 (en) | 2001-07-27 | 2001-07-27 | Polypectomy device and method |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003024348A1 true WO2003024348A1 (en) | 2003-03-27 |
Family
ID=27129692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/023833 WO2003024348A1 (en) | 2001-07-27 | 2002-07-26 | Polypectomy device and method |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1416870A4 (en) |
JP (1) | JP2005502423A (en) |
CA (1) | CA2454354A1 (en) |
WO (1) | WO2003024348A1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9277962B2 (en) | 2010-03-26 | 2016-03-08 | Aesculap Ag | Impedance mediated control of power delivery for electrosurgery |
US9339323B2 (en) | 2005-05-12 | 2016-05-17 | Aesculap Ag | Electrocautery method and apparatus |
US9872724B2 (en) | 2012-09-26 | 2018-01-23 | Aesculap Ag | Apparatus for tissue cutting and sealing |
US10130411B2 (en) | 2010-03-26 | 2018-11-20 | Aesculap Ag | Impedance mediated control of power delivery for electrosurgery |
US10314642B2 (en) | 2005-05-12 | 2019-06-11 | Aesculap Ag | Electrocautery method and apparatus |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11786296B2 (en) | 2019-02-15 | 2023-10-17 | Accularent, Inc. | Instrument for endoscopic posterior nasal nerve ablation |
US11534235B2 (en) | 2019-04-04 | 2022-12-27 | Acclarent, Inc. | Needle instrument for posterior nasal neurectomy ablation |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5318564A (en) * | 1992-05-01 | 1994-06-07 | Hemostatic Surgery Corporation | Bipolar surgical snare and methods of use |
US5437665A (en) * | 1993-10-12 | 1995-08-01 | Munro; Malcolm G. | Electrosurgical loop electrode instrument for laparoscopic surgery |
US6176858B1 (en) * | 1998-11-25 | 2001-01-23 | Medsys S.A. | Electrosurgical loop and instrument for laparoscopic surgery |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5122147A (en) * | 1991-04-05 | 1992-06-16 | Sewell Jr Frank K | Polyp marking device and method |
US5746747A (en) * | 1994-05-13 | 1998-05-05 | Mckeating; John A. | Polypectomy instrument |
US5452513A (en) * | 1994-06-29 | 1995-09-26 | Eric Hulsman | Suture cutter |
JP3244660B2 (en) * | 1998-08-17 | 2002-01-07 | 旭光学工業株式会社 | Endoscope treatment tool |
US6077277A (en) * | 1999-04-05 | 2000-06-20 | Starion Instruments, Inc. | Suture welding device |
-
2002
- 2002-07-26 WO PCT/US2002/023833 patent/WO2003024348A1/en not_active Application Discontinuation
- 2002-07-26 CA CA002454354A patent/CA2454354A1/en not_active Abandoned
- 2002-07-26 EP EP02798909A patent/EP1416870A4/en not_active Withdrawn
- 2002-07-26 JP JP2003528248A patent/JP2005502423A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5318564A (en) * | 1992-05-01 | 1994-06-07 | Hemostatic Surgery Corporation | Bipolar surgical snare and methods of use |
US5437665A (en) * | 1993-10-12 | 1995-08-01 | Munro; Malcolm G. | Electrosurgical loop electrode instrument for laparoscopic surgery |
US6176858B1 (en) * | 1998-11-25 | 2001-01-23 | Medsys S.A. | Electrosurgical loop and instrument for laparoscopic surgery |
Non-Patent Citations (1)
Title |
---|
See also references of EP1416870A4 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9339323B2 (en) | 2005-05-12 | 2016-05-17 | Aesculap Ag | Electrocautery method and apparatus |
US10314642B2 (en) | 2005-05-12 | 2019-06-11 | Aesculap Ag | Electrocautery method and apparatus |
US9277962B2 (en) | 2010-03-26 | 2016-03-08 | Aesculap Ag | Impedance mediated control of power delivery for electrosurgery |
US10130411B2 (en) | 2010-03-26 | 2018-11-20 | Aesculap Ag | Impedance mediated control of power delivery for electrosurgery |
US9872724B2 (en) | 2012-09-26 | 2018-01-23 | Aesculap Ag | Apparatus for tissue cutting and sealing |
Also Published As
Publication number | Publication date |
---|---|
JP2005502423A (en) | 2005-01-27 |
EP1416870A1 (en) | 2004-05-12 |
CA2454354A1 (en) | 2003-03-27 |
EP1416870A4 (en) | 2005-12-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6616659B1 (en) | Polypectomy device and method | |
US6616654B2 (en) | Polypectomy device and method | |
US8262655B2 (en) | Bipolar forceps | |
US9827008B2 (en) | Snare with loop made of heat shrinkable shape memory material and method of use thereof | |
US8579897B2 (en) | Bipolar forceps | |
US5423814A (en) | Endoscopic bipolar coagulation device | |
JP4242491B2 (en) | Endoscopic treatment device | |
JP5563485B2 (en) | Polyp removal device and method of use | |
JP5340722B2 (en) | Endoscopic treatment tool | |
ES2338248T3 (en) | FLEXIBLE ENDOSCOPIC CATHETER WITH A FINAL EFFECTOR TO COAGULATE AND SEPARATE TISSUE. | |
US9700345B2 (en) | Snare with retractable engaging members | |
US20020049442A1 (en) | Biopsy sampler | |
WO2009067649A2 (en) | Bipolar forceps having a cutting element | |
EP1948027B1 (en) | Tissue cutting devices having hemostasis capability | |
AU2019260152B2 (en) | Multifunctional high-frequency electric knife | |
JP3235996U (en) | Medical connection device | |
GB2460242A (en) | Morcellating laparoscopic instrument with bipolar electrodes and double skin wall. | |
WO2003024348A1 (en) | Polypectomy device and method | |
WO2021234508A1 (en) | Polypectomy device for excision of polyps and method employed thereof | |
JP2003290229A (en) | Examinee sampling instrument |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG UZ VN YU ZA ZM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2003528248 Country of ref document: JP Ref document number: 2454354 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002798909 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2002798909 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 2002798909 Country of ref document: EP |