WO2003020913A3 - Anopheles gambiae odorant receptors and genes - Google Patents

Anopheles gambiae odorant receptors and genes Download PDF

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Publication number
WO2003020913A3
WO2003020913A3 PCT/US2002/028315 US0228315W WO03020913A3 WO 2003020913 A3 WO2003020913 A3 WO 2003020913A3 US 0228315 W US0228315 W US 0228315W WO 03020913 A3 WO03020913 A3 WO 03020913A3
Authority
WO
WIPO (PCT)
Prior art keywords
odorant receptor
methods
genes
anopheles gambiae
receptor genes
Prior art date
Application number
PCT/US2002/028315
Other languages
French (fr)
Other versions
WO2003020913A2 (en
Inventor
Kevin J Lee
Jane Ong
Thuy-Ai T Nguyen
Brian Kloss
Original Assignee
Sentigen Corp
Kevin J Lee
Jane Ong
Thuy-Ai T Nguyen
Brian Kloss
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sentigen Corp, Kevin J Lee, Jane Ong, Thuy-Ai T Nguyen, Brian Kloss filed Critical Sentigen Corp
Priority to AU2002326834A priority Critical patent/AU2002326834A1/en
Publication of WO2003020913A2 publication Critical patent/WO2003020913A2/en
Publication of WO2003020913A3 publication Critical patent/WO2003020913A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Insects & Arthropods (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to Anopheles gambiae odorant receptor genes and methods for identifying odorant receptor genes. The invention provides nucleotide sequences of Anopheles gambiae odorant receptor genes, amino acid sequences of their encoded proteins (including peptides or polypeptides), and related products and methods. The nucleic acids of the invention may be operatively linked to promoter sequences and transformed into host cells. Methods of production of an odorant receptor protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Antibodies to an odorant receptor protein, and derivatives and analogs thereof, are provided. Methods for identifying molecules that bind or modulate the activity of these odorant receptor genes are provided. Molecules found to bind or modulate the activity of odorant receptor genes may be formulated into pest control agents by providing a carrier. In a preferred embodiment, molecules that bind or modulate the activity of an odorant receptor gene from Anopheles gambiae but not others is desired. Methods to modify the insect behavior by modifying an odorant receptor are also provided.
PCT/US2002/028315 2001-09-04 2002-09-04 Anopheles gambiae odorant receptors and genes WO2003020913A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002326834A AU2002326834A1 (en) 2001-09-04 2002-09-04 Anopheles gambiae odorant receptors and genes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31740101P 2001-09-04 2001-09-04
US60/317,401 2001-09-04

Publications (2)

Publication Number Publication Date
WO2003020913A2 WO2003020913A2 (en) 2003-03-13
WO2003020913A3 true WO2003020913A3 (en) 2006-12-07

Family

ID=23233475

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/028315 WO2003020913A2 (en) 2001-09-04 2002-09-04 Anopheles gambiae odorant receptors and genes

Country Status (2)

Country Link
AU (1) AU2002326834A1 (en)
WO (1) WO2003020913A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7314723B2 (en) * 2001-01-26 2008-01-01 Vanderbilt University Method of identifying chemical agents which stimulate odorant receptors of sensory neurons
AU2002332534B2 (en) * 2001-08-14 2007-08-16 Sentisearch, Inc. Nucleic acids and proteins of insect Or83b odorant receptor genes and uses thereof
CA2523489A1 (en) 2003-04-24 2004-11-25 Vanderbilt University Compositions and methods for controlling insects
US10473645B2 (en) 2014-08-26 2019-11-12 Universite De Geneve Methods for identifying a receptor for a ligand and uses thereof
JP6875815B2 (en) * 2016-09-29 2021-05-26 住友化学株式会社 Olfactory receptor co-receptor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FOX A.N. ET AL.: "Candidate Odorant Receptors from the Malaria Vector Mosquito Anopheles gambiae and Evidence of Down-Regulation in Responses to Blood Feasting", PNAS, vol. 98, no. 25, 4 December 2001 (2001-12-04), pages 14693 - 14697, XP003004433 *
HALLEM E.A. ET AL.: "Mosquito Receptor for Human-Sweat Odorant", NATURE, vol. 427, 15 January 2004 (2004-01-15), pages 212 - 213, XP003004435 *
HILL C.A. ET AL.: "G Protein-Coupled Receptors in Anopheles gambiae", SCIENCE, vol. 298, 4 October 2002 (2002-10-04), pages 176 - 178, XP003004434 *

Also Published As

Publication number Publication date
AU2002326834A8 (en) 2007-02-01
AU2002326834A1 (en) 2003-03-18
WO2003020913A2 (en) 2003-03-13

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