WO2002085409A3 - Methods and compositions for inducing an immune response to an antigen - Google Patents

Methods and compositions for inducing an immune response to an antigen Download PDF

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Publication number
WO2002085409A3
WO2002085409A3 PCT/US2001/045717 US0145717W WO02085409A3 WO 2002085409 A3 WO2002085409 A3 WO 2002085409A3 US 0145717 W US0145717 W US 0145717W WO 02085409 A3 WO02085409 A3 WO 02085409A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
antigen
inducing
immune response
Prior art date
Application number
PCT/US2001/045717
Other languages
French (fr)
Other versions
WO2002085409A2 (en
Inventor
Thomas J Schall
Dale Talbot
Robert Berkovitz
Wei Zheng
Maureen Howard
Brett Premack
Original Assignee
Chemocentryx
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx filed Critical Chemocentryx
Priority to AU2002228729A priority Critical patent/AU2002228729A1/en
Publication of WO2002085409A2 publication Critical patent/WO2002085409A2/en
Publication of WO2002085409A3 publication Critical patent/WO2002085409A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This application relates generally to enhancing immune responses. Such immune responses may be elicited by vaccine administration. Compositions and methods for inducing or enhancing an immune response to an antigen are provided. The compositions and methods are useful for, among other things, vaccine formulation for therapeutic and prophylactic vaccination (immunization) and for production of useful antibodies (e.g., monoclonal antibodies for therapeutic or diagnostic use).
PCT/US2001/045717 2001-04-12 2001-10-30 Methods and compositions for inducing an immune response to an antigen WO2002085409A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002228729A AU2002228729A1 (en) 2001-04-12 2001-10-30 Methods and compositions for inducing an immune response to an antigen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83481401A 2001-04-12 2001-04-12
US09/834,814 2001-04-12

Publications (2)

Publication Number Publication Date
WO2002085409A2 WO2002085409A2 (en) 2002-10-31
WO2002085409A3 true WO2002085409A3 (en) 2002-12-27

Family

ID=25267873

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/045717 WO2002085409A2 (en) 2001-04-12 2001-10-30 Methods and compositions for inducing an immune response to an antigen

Country Status (2)

Country Link
AU (1) AU2002228729A1 (en)
WO (1) WO2002085409A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003035106A1 (en) * 2001-10-24 2003-05-01 Chemocentryx Methods and compositions for inducing an immune response by co-administering a chemokine with an antigen

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998004282A1 (en) * 1996-07-25 1998-02-05 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with allogeneic cytokine-secreting cells
WO1999029728A1 (en) * 1997-12-11 1999-06-17 University Of Maryland Biotechnology Institute Method and composition to enhance the efficacy of a vaccine using chemokines
EP0974357A1 (en) * 1998-07-16 2000-01-26 Schering-Plough Chemokines as adjuvants of immune response
WO2001080887A2 (en) * 2000-04-21 2001-11-01 Chemocentryx, Inc. Methods and chemokin compositions for inducing an immune response

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998004282A1 (en) * 1996-07-25 1998-02-05 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with allogeneic cytokine-secreting cells
WO1999029728A1 (en) * 1997-12-11 1999-06-17 University Of Maryland Biotechnology Institute Method and composition to enhance the efficacy of a vaccine using chemokines
EP0974357A1 (en) * 1998-07-16 2000-01-26 Schering-Plough Chemokines as adjuvants of immune response
WO2001080887A2 (en) * 2000-04-21 2001-11-01 Chemocentryx, Inc. Methods and chemokin compositions for inducing an immune response

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DE GIOVANNI CARLA ET AL: "The prospects for cancer gene therapy.", INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, vol. 22, no. 12, December 2000 (2000-12-01), pages 1025 - 1032, XP002218907, ISSN: 0192-0561 *
GREAVES DAVID R ET AL: "Chemokines and myeloid cell recruitment.", MICROBES AND INFECTION, vol. 2, no. 3, March 2000 (2000-03-01), pages 331 - 336, XP002218908, ISSN: 1286-4579 *

Also Published As

Publication number Publication date
WO2002085409A2 (en) 2002-10-31
AU2002228729A1 (en) 2002-11-05

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