WO2002066506A3 - Use of casb7439 (ash2) in the immunotherapy of breast cancer - Google Patents

Use of casb7439 (ash2) in the immunotherapy of breast cancer Download PDF

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Publication number
WO2002066506A3
WO2002066506A3 PCT/EP2002/001649 EP0201649W WO02066506A3 WO 2002066506 A3 WO2002066506 A3 WO 2002066506A3 EP 0201649 W EP0201649 W EP 0201649W WO 02066506 A3 WO02066506 A3 WO 02066506A3
Authority
WO
WIPO (PCT)
Prior art keywords
casb7439
breast cancer
ash2
immunotherapy
disclosed
Prior art date
Application number
PCT/EP2002/001649
Other languages
French (fr)
Other versions
WO2002066506A2 (en
Inventor
Y De Bassols Carlota Vinals
Jean-Pol Cassart
Original Assignee
Glaxosmithkline Biolog Sa
Y De Bassols Carlota Vinals
Jean-Pol Cassart
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa, Y De Bassols Carlota Vinals, Jean-Pol Cassart filed Critical Glaxosmithkline Biolog Sa
Priority to AU2002249221A priority Critical patent/AU2002249221A1/en
Publication of WO2002066506A2 publication Critical patent/WO2002066506A2/en
Publication of WO2002066506A3 publication Critical patent/WO2002066506A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The use of CASB7439 polypeptides and polynucleotides, and variants, immunogenic fragments and fusions thereof, and of immunogenic compositions thereof, in the prophylaxis, treatment and diagnosis of breast tumours is disclosed. Methods of diagnosing the presence of breast cancer or a susceptility to breast cancer in a subject related to the expression or activity of a CASB7439 polynucleotide or polypeptide are also disclosed.
PCT/EP2002/001649 2001-02-21 2002-02-15 Use of casb7439 (ash2) in the immunotherapy of breast cancer WO2002066506A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002249221A AU2002249221A1 (en) 2001-02-21 2002-02-15 Use of casb7439 (ash2) in the immunotherapy of breast cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0104259.7 2001-02-21
GBGB0104259.7A GB0104259D0 (en) 2001-02-21 2001-02-21 Novel compounds

Publications (2)

Publication Number Publication Date
WO2002066506A2 WO2002066506A2 (en) 2002-08-29
WO2002066506A3 true WO2002066506A3 (en) 2002-12-19

Family

ID=9909202

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/001649 WO2002066506A2 (en) 2001-02-21 2002-02-15 Use of casb7439 (ash2) in the immunotherapy of breast cancer

Country Status (3)

Country Link
AU (1) AU2002249221A1 (en)
GB (1) GB0104259D0 (en)
WO (1) WO2002066506A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0111974D0 (en) * 2001-05-16 2001-07-04 Glaxosmithkline Biolog Sa Novel Compounds
AU2010252012A1 (en) 2009-05-27 2011-12-22 Glaxosmithkline Biologicals S.A. CASB7439 constructs
JP2014512409A (en) 2011-04-28 2014-05-22 エスティーシー． ユーエヌエム Lipid bilayer (protocell) supported on porous nanoparticles for targeted delivery and method of use thereof
GB201520592D0 (en) * 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
WO2017120504A1 (en) 2016-01-08 2017-07-13 Durfee Paul N Osteotropic nanoparticles for prevention or treatment of bone metastases
US11344629B2 (en) 2017-03-01 2022-05-31 Charles Jeffrey Brinker Active targeting of cells by monosized protocells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001002828A2 (en) * 1999-07-07 2001-01-11 Tularik Inc. Diagnosis of cancer by detecting ash2 polypeptides or polynucleotides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001002828A2 (en) * 1999-07-07 2001-01-11 Tularik Inc. Diagnosis of cancer by detecting ash2 polypeptides or polynucleotides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERTHET F.-X. ET AL.: "Applied genome research in the field of human vaccines", JOURNAL OF BIOTECHNOLOGY, vol. 85, no. 2, 13 February 2001 (2001-02-13), pages 213 - 226, XP002214628 *
DATABASE SWISS-PROT [online] "ASH_2 HUMAN", XP002214631, retrieved from EMBL Database accession no. q99929 *
KOBAYASHI H. ET AL.: "Defining promiscuous MHC class II Helper T-cell epitopes for the Her2/neu Tumor Antigen", CANCER RESEARCH, vol. 60, 15 September 2000 (2000-09-15), pages 5228 - 5236, XP002214629 *

Also Published As

Publication number Publication date
AU2002249221A1 (en) 2002-09-04
GB0104259D0 (en) 2001-04-11
WO2002066506A2 (en) 2002-08-29

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