WO2002061083A1 - Novel g protein-coupled receptor protein and dna thereof - Google Patents

Novel g protein-coupled receptor protein and dna thereof Download PDF

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Publication number
WO2002061083A1
WO2002061083A1 PCT/JP2002/000635 JP0200635W WO02061083A1 WO 2002061083 A1 WO2002061083 A1 WO 2002061083A1 JP 0200635 W JP0200635 W JP 0200635W WO 02061083 A1 WO02061083 A1 WO 02061083A1
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WO
WIPO (PCT)
Prior art keywords
protein
same
novel
coupled receptor
dna
Prior art date
Application number
PCT/JP2002/000635
Other languages
French (fr)
Japanese (ja)
Inventor
Keiji Iwamoto
Shuji Sato
Yasushi Shintani
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Publication of WO2002061083A1 publication Critical patent/WO2002061083A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A novel G protein-coupled receptor protein containing an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:1, a polynucleotide encoding the same, etc. are provided. The human-origin protein and DNA encoding the same as described above are usable in: (1) determining a ligand to the above protein; (2) preventives and/or remedies for diseases in association with the hypofunction of the above protein; (3) screening a compound (an agonist, an antagonist, etc.) capable of altering the binding properties of the above protein to a ligand, etc.
PCT/JP2002/000635 2001-01-30 2002-01-29 Novel g protein-coupled receptor protein and dna thereof WO2002061083A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001021581 2001-01-30
JP2001-21581 2001-01-30
JP2001-102485 2001-03-30
JP2001102485 2001-03-30

Publications (1)

Publication Number Publication Date
WO2002061083A1 true WO2002061083A1 (en) 2002-08-08

Family

ID=26608518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/000635 WO2002061083A1 (en) 2001-01-30 2002-01-29 Novel g protein-coupled receptor protein and dna thereof

Country Status (1)

Country Link
WO (1) WO2002061083A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003051925A1 (en) * 2001-12-19 2003-06-26 Bayer Healthcare Ag Human secretin-type gpcr (latrophilin)
EP1383790A4 (en) * 2001-03-28 2006-08-09 Applera Corp Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr protein, and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021999A1 (en) * 1998-10-09 2000-04-20 Chugai Research Institute For Molecular Medicine, Inc. Novel g protein-coupled receptors
WO2000034473A2 (en) * 1998-12-10 2000-06-15 Zymogenetics, Inc. Seven transmembrane domain receptor zsig56

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021999A1 (en) * 1998-10-09 2000-04-20 Chugai Research Institute For Molecular Medicine, Inc. Novel g protein-coupled receptors
WO2000034473A2 (en) * 1998-12-10 2000-06-15 Zymogenetics, Inc. Seven transmembrane domain receptor zsig56

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1383790A4 (en) * 2001-03-28 2006-08-09 Applera Corp Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr protein, and uses thereof
WO2003051925A1 (en) * 2001-12-19 2003-06-26 Bayer Healthcare Ag Human secretin-type gpcr (latrophilin)

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