WO2001087408A2 - Method and apparatus for applying electromagnetic radiation into human tissues for producing a therapeutic effect - Google Patents
Method and apparatus for applying electromagnetic radiation into human tissues for producing a therapeutic effect Download PDFInfo
- Publication number
- WO2001087408A2 WO2001087408A2 PCT/IL2001/000429 IL0100429W WO0187408A2 WO 2001087408 A2 WO2001087408 A2 WO 2001087408A2 IL 0100429 W IL0100429 W IL 0100429W WO 0187408 A2 WO0187408 A2 WO 0187408A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- flash lamp
- tubular element
- reflector
- lamp
- prism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/00458—Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B2018/1807—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using light other than laser radiation
Definitions
- the invention relates to devices and methods that use electromagnetic energy to produce therapeutic effects.
- Po high specific power of the impulse
- the Po may range from 1,000,000 to 100,000,000 Watt/sq.cm.
- the Po may range from 1 ,000 to 100,000 Watt/sq.cm.
- Such high powers lead to explosion-like processes in human tissues and to undesirable side-effects, such as burns.
- a desired temperature e.g., 70-80°C
- Recent methods of decreasing the negative consequences of tissue overheating include the preliminary cooling of the treated surface.
- One method is to apply various gels or anesthetic creams, such as EMLA, etc. While all of the current methods make these procedures less painful, they do not deal with the cause of the pain, which is large amount of applied energy.
- FIG. 1 shows the graph 100 of the temperature change after treatment with the
- the area limited by the 80°C line 102 ( ⁇ active laser time and ⁇ active flash lamp time) shows the necessary and the sufficient amount of energy required for the therapeutic effect to occur.
- the graph 100 also shows how much extraneous energy gets into tissues when the existing methods are applied.
- Such systems include a system for cooling a flash lamp that includes a tubular element made of material through which a continuous flow of distilled water passes.
- the flash lamp resides within the tube.
- the tube is made of a material that is transparent to the light produced by the lamp, but that filters the harmful UV specter.
- the spectral characteristics of the filter are chosen in such a way that it passes only red and lower infrared light (650 - I200nm).
- a first reflector for reflecting light produced by the lamp also resides within the tube.
- Methods of the present invention include the supply of electrical power to the flash lamp. Power is supplied to the lamp as a series of short, low power impulses that result in the elimination of the overheating of a tissue being treated.
- FIG. 1 illustrates a graph showing the change in temperature of human tissue when a conventional laser or a conventional flash lamp is used
- FIG. 2 illustrates a graph showing the change in temperature of human tissue resulting from the use of the systems and methods of the present invention
- FIG. 3 illustrates the use of an elliptical prism in accordance with one embodiment of the present invention
- FIG. 4 illustrates a tube used for cooling the flash lamp in accordance with one embodiment of the present invention
- FIG. 5 illustrates the placement of a first reflector inside the cooling system in accordance with two embodiments of the present invention
- FIGS. 6A and 6B illustrate a series or pulses produced by a power supply used to energize the flash lamp
- FIG. 7 illustrates a first power supply in accordance with one embodiment of the present invention
- FIG. 8 illustrates a second power supply in accordance with one embodiment of the present invention
- FIG. 9A illustrates the placement of a second reflector inside the cooling system in accordance with one embodiment of the present invention.
- FIG. 9B is a sectional view of the placement of a second reflector inside the cooling system in accordance with one embodiment of the present invention.
- FIG. 2 shows the graph 200 of the temperature change after applying any of the disclosed methods.
- the graph 200 shows that the tissue temperature 202 resulting from the applied energy is only a little bit more than the temperature required (80°) in order to get the therapeutic effect.
- the temperatures of both the tissues absorbing the energy and of the tissues surrounding the treated surface are substantially lowered.
- the rated power of the impulse Po, when applying the present method, is 5 to 100 Watt/sq.cm, which cannot damage human tissues.
- FIG. 3 illustrates one embodiment of the cooling system 300.
- the system 300 includes an elliptical prism 302, a tube 306, and a flash lamp 304.
- the prism 302 while illustrated as having an elliptical shape, may assume other shapes such as rectangular, conic, etc.
- the prism 302 is optically transparent for a desired part of the specter.
- the elliptical prism may be made of red pyrex.
- the source of electromagnetic energy of the present invention can be the flash lamp 304.
- the flash lamp 304 is a conventional flash lamp filled with Krypton under pressure (e.g., 8 kg/sq.cm.) to allow the increase of output energy in a desired part of the specter.
- Krypton under pressure e.g. 8 kg/sq.cm.
- the specific density of the current flowing through the flash lamp is about 100-
- the flash lamp 304 is positioned coaxially inside the tube 306.
- the tube 306 is
- the prism may be transparent.
- the tube can be used to form a
- the tube 306 may
- the tube produced by that dispersion is absorbed by a liquid continuously flowing through the tube.
- the flowing liquid is preferably a coolant, such as distilled water.
- the cooling tube 306 and the prism 302 form an integral unit. That is, the flash
- prism 302 is also cooled by the liquid that flows through the tube 306.
- a system 400 for obtaining a desired spectrum (e.g., 650-
- 1200nm includes a tube 406 with a section 410 designed for attaching a prism thereto.
- the shape of section 410 is rectangular.
- the section 410 allows the attachment of prisms of various geometries (see the rectangular prism 402 and the trapezoidal prism 408) and also allows their quick replacement.
- the section 410 may be made of the same material that the prism is made of.
- the flash lamp 304 is located coaxially inside the tube 406.
- a coolant flows through the tube 406, cooling the lamp 304 and the attached prism.
- the tube 406 may
- the desired shape of the prism may depend on the size of the tissue area to be
- the light emitted by the flash lamp 304 passes through section 410 and through
- the attached prism e.g., 402 or 408 and is then projected on the area to be treated.
- FIG. 5 illustrates the placement of a reflector inside the cooling system in
- FIG. 5 illustrates a side view
- the reflector 502 is placed inside the tube 406 for an embodiment that includes the use of the rectangular prism 402.
- the reflector is
- the reflector can
- the reflector 502 may be used with the second embodiment in FIG. 5.
- the second embodiment includes the use of an elliptical prism 302.
- the reflector 502 is placed inside the tube in the vicinity of the flash lamp 304 and
- FIGS. 6A and 6B illustrate a series of pulses produced by a power supply used to drive the flash lamp.
- the method of the present invention includes the supply of power to the flash lamp 304.
- power is supplied to the flash lamp as a sequence of short, low power impulses. This results in the application of electromagnetic energy to the tissue such that the overheating of the tissue is avoided while the temperature and duration of the energy application are sufficient to produce a therapeutic effect (e.g., the coagulation of protein).
- the coagulation time of proteins in the tissue upon application of the energy is estimated to be in between 0.1 and 2 seconds.
- energy is applied to the tissue for that period of time.
- the flash lamp 304 is supplied with power for a period of time in between 0.1 and 2 seconds (see numeral 601).
- the power is supplied as a series of pulses, the pulse frequency being set in between 10 to 200 Hz (see numeral 603).
- the impulse ratio may range in between .01 and 1 (see numeral 605).
- the impulse ratio is defined as the pulse width divided by the pulse period.
- 6A is in the range from about 0.01 to 0.5 J/sq.- cm.
- the total energy applied to the tissues corresponding to a series of impulses is in the range from about .05 to 15 J/sq.-cm.
- a continuous series of impulses 61 1 can be supplied for a period ranging from 0.1 to 2 seconds. That continuous series of impulses 61 1 may be repeated a number of times (e.g., five times as shown), with a repetition period of 0.3 to 1.5 seconds.
- the aforementioned schemes allow the increase of energy application time to up to 4 seconds without causing overheating of the skin. Further, the application of energy on the tissues by use of those schemes produces the desired therapeutic effect.
- the flash lamp 304 is thus uniquely used, so that the feeding impulse voltage is a little bit higher than the simmer mode voltage.
- the impulse voltage lies within the limits of 60-140 volts, which, together with the high krypton pressure, allows maximization of spectrum radiation in the red zone.
- the flash lamp 304 may wait for the incoming impulse in the simmer mode and turns off automatically after 5 minutes.
- an automatic calibration of the electromagnetic source e.g., lamp and prism
- Adjustment of the flash lamp energy is performed through the change of the initial voltage of the flash lamp power source or through addition of an impulse to the main impulse series.
- Performance of these steps in addition to the low voltage of the power source, increases the life cycle of the flash lamp 304 while preserve the required energy level. For example, the number of impulses supplied to the flash lamp 304 before its replacement may reach 10,000,000. This allows the use of the same flash lamp for 5-6 years.
- the flash lamp power source may be constructed by storing energy in low-voltage capacitors 701 (60-140 volts) and transmitting it directly to the flash lamp through a MOSFET transistor or a PFN 703 (FIG. 7).
- the flash lamp power source can be constructed by storing energy in high-voltage capacitors 801 (300-500 volts) and transmitting the energy through an impulse transformer 803 (output voltage 60-140 volts) to the flash lamp by means of an impulse power source, controlled by a computer (not shown).
- the second method (FIG. 8).
- the first method (FIG. 7) is preferable.
- the first method avoids large outputs of energy, which can damage the patient.
- the voltage on the capacitors gets lower than the voltage of the simmer mode during an emergency impulse, the flash lamp turns off automatically. It is possible to calculate the capacity of the capacitors in such a way that in any case the maximum energy of the flash lamp is below a dangerous limit.
- FIG. 9A illustrates the placement of a second reflector inside the cooling system while FIG. 9B is a sectional view of FIG. 9A.
- the cooling system comprises an external rectangular casing 901 made of a heat-conducting material, e.g., a metal. Within the casing 901, a space 905 is provided for deploying therein the cooling tube 906.
- a second reflector 907 is provided, which is situated beneath the tube 906 and surrounds the tube 906 from below. Through the open upper part of the casing 901, a prism 402 is inserted and secured on the attachment section of the cooling tube 906.
- a through-going channel 903 is made in the casing.
- an additional means for cooling is provided, and thus the second reflector 907, . positioned adjacent to the channel 903, is efficiently cooled.
- the prism 402 is cooled as well, since its bottom part contacts metallic walls of the casing.
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Electromagnetism (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001256642A AU2001256642A1 (en) | 2000-05-19 | 2001-05-15 | Method and apparatus for applying electromagnetic radiation into human tissues for producing a therapeutic effect |
IL15281401A IL152814A0 (en) | 2000-05-19 | 2001-05-15 | Method and apparatus for applying electromagnetic radiation into human tissues for producing a therapeutic effect |
IL16175701A IL161757A0 (en) | 2000-05-19 | 2001-05-15 | A method of energizing a flash lampfor applying electromagnetic radiation into human tissues |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20524400P | 2000-05-19 | 2000-05-19 | |
US60/205,244 | 2000-05-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001087408A2 true WO2001087408A2 (en) | 2001-11-22 |
WO2001087408A3 WO2001087408A3 (en) | 2002-06-06 |
Family
ID=22761417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2001/000429 WO2001087408A2 (en) | 2000-05-19 | 2001-05-15 | Method and apparatus for applying electromagnetic radiation into human tissues for producing a therapeutic effect |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2001256642A1 (en) |
IL (2) | IL161757A0 (en) |
WO (1) | WO2001087408A2 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2838042A1 (en) * | 2002-04-08 | 2003-10-10 | Eurofeedback Sa | Epilation device has a flash generator for skin treatment with capacitive discharge devices controlled by electronic switches, with the energy of an individual device being such that failure of a switch will not cause any lesion |
WO2004047921A1 (en) * | 2002-11-28 | 2004-06-10 | Koninklijke Philips Electronics N.V. | Device for treating human skin by means of radiation |
DE102004017547A1 (en) * | 2004-03-31 | 2005-10-20 | Ide Gmbh | Coherent, pulsed light applying method for e.g. hair therapy, involves applying light on places to be treated for stimulating cells in that places, where frequency of light varies between certain range in primary frequency-spectrum |
WO2007007167A1 (en) * | 2005-07-13 | 2007-01-18 | Perkinelmer Optoelectronics Gmbh & Co. Kg | Flashlamp cartridge for removable connection to a socket |
FR2889439A1 (en) * | 2005-08-05 | 2007-02-09 | Eurofeedback Sa | HANDPIECE FOR TREATMENT APPARATUS BY TRANSMITTING LIGHT FLASKS |
FR2929832A1 (en) * | 2008-04-10 | 2009-10-16 | Eurofeedback Soc Par Actions S | DEVICE AND TREATMENT BY LIGHT EMITTING FLASH |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5337741A (en) * | 1991-06-21 | 1994-08-16 | Diamond Donald A | Photo radiation treatment apparatus and method |
US5405368A (en) * | 1992-10-20 | 1995-04-11 | Esc Inc. | Method and apparatus for therapeutic electromagnetic treatment |
US5836999A (en) * | 1995-09-28 | 1998-11-17 | Esc Medical Systems Ltd. | Method and apparatus for treating psoriasis using pulsed electromagnetic radiation |
US5855595A (en) * | 1994-04-04 | 1999-01-05 | Asahi Kogaku Kogyo Kabushiki Kaisha | Tumor treatment apparatus |
-
2001
- 2001-05-15 IL IL16175701A patent/IL161757A0/en unknown
- 2001-05-15 IL IL15281401A patent/IL152814A0/en not_active IP Right Cessation
- 2001-05-15 AU AU2001256642A patent/AU2001256642A1/en not_active Abandoned
- 2001-05-15 WO PCT/IL2001/000429 patent/WO2001087408A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5337741A (en) * | 1991-06-21 | 1994-08-16 | Diamond Donald A | Photo radiation treatment apparatus and method |
US5405368A (en) * | 1992-10-20 | 1995-04-11 | Esc Inc. | Method and apparatus for therapeutic electromagnetic treatment |
US5855595A (en) * | 1994-04-04 | 1999-01-05 | Asahi Kogaku Kogyo Kabushiki Kaisha | Tumor treatment apparatus |
US5836999A (en) * | 1995-09-28 | 1998-11-17 | Esc Medical Systems Ltd. | Method and apparatus for treating psoriasis using pulsed electromagnetic radiation |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1352615A1 (en) * | 2002-04-08 | 2003-10-15 | Eurofeedback | Flashlight treatment device |
EP1602340A2 (en) * | 2002-04-08 | 2005-12-07 | Eurofeedback | Flashlight treatment device |
EP1602340A3 (en) * | 2002-04-08 | 2006-01-11 | Eurofeedback | Flashlight treatment device |
FR2838042A1 (en) * | 2002-04-08 | 2003-10-10 | Eurofeedback Sa | Epilation device has a flash generator for skin treatment with capacitive discharge devices controlled by electronic switches, with the energy of an individual device being such that failure of a switch will not cause any lesion |
US7517344B2 (en) | 2002-11-28 | 2009-04-14 | Koninklijke Philips Electronics N.V. | Device for treating human skin by means of radiation |
WO2004047921A1 (en) * | 2002-11-28 | 2004-06-10 | Koninklijke Philips Electronics N.V. | Device for treating human skin by means of radiation |
JP2006507867A (en) * | 2002-11-28 | 2006-03-09 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Device for treating human skin with radiation |
JP2011050792A (en) * | 2002-11-28 | 2011-03-17 | Koninkl Philips Electronics Nv | Device for treating human skin by means of radiation |
DE102004017547A1 (en) * | 2004-03-31 | 2005-10-20 | Ide Gmbh | Coherent, pulsed light applying method for e.g. hair therapy, involves applying light on places to be treated for stimulating cells in that places, where frequency of light varies between certain range in primary frequency-spectrum |
WO2007007167A1 (en) * | 2005-07-13 | 2007-01-18 | Perkinelmer Optoelectronics Gmbh & Co. Kg | Flashlamp cartridge for removable connection to a socket |
FR2889439A1 (en) * | 2005-08-05 | 2007-02-09 | Eurofeedback Sa | HANDPIECE FOR TREATMENT APPARATUS BY TRANSMITTING LIGHT FLASKS |
EP1749495A3 (en) * | 2005-08-05 | 2008-03-26 | Eurofeedback | Handpiece for a treatment apparatus using flashes of light |
FR2929832A1 (en) * | 2008-04-10 | 2009-10-16 | Eurofeedback Soc Par Actions S | DEVICE AND TREATMENT BY LIGHT EMITTING FLASH |
WO2009136104A2 (en) * | 2008-04-10 | 2009-11-12 | Eurofeedback | Device and treatment by flashing light emissions |
WO2009136104A3 (en) * | 2008-04-10 | 2010-03-11 | Eurofeedback | Device and treatment by flashing light emissions |
ES2424051A1 (en) * | 2008-04-10 | 2013-09-26 | Eurofeedback | Device and treatment by flashing light emissions |
Also Published As
Publication number | Publication date |
---|---|
IL161757A0 (en) | 2005-11-20 |
AU2001256642A1 (en) | 2001-11-26 |
WO2001087408A3 (en) | 2002-06-06 |
IL152814A0 (en) | 2003-06-24 |
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