WO2001083782A3 - Nouvelles proteases - Google Patents
Nouvelles proteases Download PDFInfo
- Publication number
- WO2001083782A3 WO2001083782A3 PCT/US2001/014431 US0114431W WO0183782A3 WO 2001083782 A3 WO2001083782 A3 WO 2001083782A3 US 0114431 W US0114431 W US 0114431W WO 0183782 A3 WO0183782 A3 WO 0183782A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- protease
- novel proteases
- various
- protease polypeptides
- stk
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001580389A JP2004504812A (ja) | 2000-05-04 | 2001-05-04 | 新規プロテアーゼ |
AU2001259473A AU2001259473A1 (en) | 2000-05-04 | 2001-05-04 | Novel proteases |
CA002408105A CA2408105A1 (fr) | 2000-05-04 | 2001-05-04 | Nouvelles proteases |
EP01933003A EP1294901A2 (fr) | 2000-05-04 | 2001-05-04 | Nouvelles proteases |
US10/275,107 US20040063107A1 (en) | 2001-05-04 | 2001-05-04 | Novel proteases |
HK03106801.3A HK1054571A1 (zh) | 2000-05-04 | 2003-09-22 | 新的蛋白酶 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20187900P | 2000-05-04 | 2000-05-04 | |
US60/201,879 | 2000-05-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001083782A2 WO2001083782A2 (fr) | 2001-11-08 |
WO2001083782A3 true WO2001083782A3 (fr) | 2003-01-23 |
Family
ID=22747660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/014431 WO2001083782A2 (fr) | 2000-05-04 | 2001-05-04 | Nouvelles proteases |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1294901A2 (fr) |
JP (1) | JP2004504812A (fr) |
AU (1) | AU2001259473A1 (fr) |
CA (1) | CA2408105A1 (fr) |
HK (1) | HK1054571A1 (fr) |
WO (1) | WO2001083782A2 (fr) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030096391A1 (en) * | 2000-12-22 | 2003-05-22 | Millennium Pharmaceuticals, Inc. | 17903, a novel human aminopeptidase and uses therefor |
US6683165B1 (en) | 1999-04-13 | 2004-01-27 | Genome Therapeutics Corporation | Human gene relating to respiratory diseases and obesity |
US20020115842A1 (en) * | 2000-09-29 | 2002-08-22 | Friddle Carl Johan | Novel human proteases and polynucleotides encoding the same |
EP1234025B1 (fr) | 1999-11-19 | 2008-08-27 | Solvay Pharmaceuticals B.V. | Enzymes humaines de la famille des metalloproteases |
EP1134286A3 (fr) * | 2000-03-14 | 2003-05-02 | Pfizer Products Inc. | Adamts polypeptides, acides nucléiques les codant et leurs applications |
AU2001253512A1 (en) * | 2000-04-13 | 2001-10-30 | Genome Therapeutics Corporation | Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease |
DE10031932A1 (de) * | 2000-06-30 | 2002-01-10 | Basf Ag | Calpain-Protease 12 |
AU2001279060A1 (en) * | 2000-07-28 | 2002-02-13 | Immunex Corporation | Metalloproteinase-disintegrin polypeptides and methods of making and use thereof |
GB0020345D0 (en) * | 2000-08-17 | 2000-10-04 | Glaxo Group Ltd | Protein |
JP2004531201A (ja) * | 2000-08-22 | 2004-10-14 | レキシコン・ジェネティクス・インコーポレーテッド | 新規ヒトプロテアーゼ及び該プロテアーゼをコードするポリヌクレオチド |
WO2002020805A2 (fr) * | 2000-09-11 | 2002-03-14 | Bayer Aktiengesellschaft | Regulation de l'enzyme similaire a la carboxypeptidase humaine |
AU2001289886A1 (en) * | 2000-09-20 | 2002-04-02 | Bayer Aktiengesellschaft | Regulation of human adam-ts 1 precursor-like protein |
WO2002026948A2 (fr) * | 2000-09-25 | 2002-04-04 | Millennium Pharmaceuticals, Inc. | 55054, une nouvelle metalloprotease humaine et ses applications |
WO2002026955A2 (fr) * | 2000-09-29 | 2002-04-04 | Lexicon Genetics Incorporated | Nouvelles proteases humaines et polynucleotides codant pour ces proteases |
EP1328623A2 (fr) * | 2000-10-04 | 2003-07-23 | Lexicon Genetics Incorporated | Nouvelles proteases humaines et polynucleotides codant pour ces proteases |
WO2002033087A2 (fr) * | 2000-10-17 | 2002-04-25 | Curagen Corporation | Proteines et acides nucleiques codant les memes |
US6689599B1 (en) * | 2000-10-20 | 2004-02-10 | Genetics Institute, Llc | Aggrecanase molecules |
CA2426588A1 (fr) * | 2000-10-26 | 2002-07-18 | Curagen Corporation | Proteines humaines, polynucleotides les codant et procedes d'utilisation correspondants |
US20020119555A1 (en) * | 2000-12-22 | 2002-08-29 | Rajasehkar Bandaru | 53014, a human metalloprotease family member and uses therefor |
JPWO2002051998A1 (ja) * | 2000-12-25 | 2004-04-30 | 山之内製薬株式会社 | 新規プロテアーゼ |
US6903201B2 (en) | 2001-01-05 | 2005-06-07 | Curagen Corporation | Proteins and nucleic acids encoding same |
WO2002057461A2 (fr) * | 2001-01-18 | 2002-07-25 | Bayer Aktiengesellschaft | Regulation de la metalloprotease a zinc de type adam-ts humaine |
EP1567642A4 (fr) | 2001-04-03 | 2006-02-08 | Bristol Myers Squibb Co | Polynucleotide codant pour une nouvelle cysteine protease de la superfamille calpain, can-12 et leurs variantes |
US7034134B2 (en) * | 2001-04-26 | 2006-04-25 | Bristol-Myers Squibb Company | Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29 |
CA2447935A1 (fr) * | 2001-06-04 | 2002-12-12 | Curagen Corporation | Nouveaux anticorps se fixant a des polypeptides antigeniques, acides nucleiques codant les antigenes et modes d'utilisation |
JP2004533848A (ja) | 2001-07-10 | 2004-11-11 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | ヒトアミノペプチダーゼnの調節 |
US7125701B2 (en) | 2001-07-27 | 2006-10-24 | Wyeth | Aggrecanase molecules |
AU2002329847B2 (en) * | 2001-08-22 | 2007-08-09 | Lexicon Pharmaceuticals, Inc. | Novel human proteases and polynucleotides encoding the same |
JP2003180384A (ja) * | 2001-09-24 | 2003-07-02 | Daiichi Fine Chemical Co Ltd | Adamts−15,−16,−17,−18及び−19 |
WO2003042379A2 (fr) * | 2001-11-13 | 2003-05-22 | Universite De Liege | Nouveau polynucleotide de desintegrine et metalloproteinase comportant une thrombospondine de type 1 et polypeptide code |
WO2003057842A2 (fr) * | 2001-12-31 | 2003-07-17 | Wyeth | Molecules d'aggrecanase |
US7078217B2 (en) | 2002-01-31 | 2006-07-18 | Wyeth | Aggrecanase molecules |
WO2003089644A1 (fr) * | 2002-04-19 | 2003-10-30 | Riken | Nouvelles proteines et adn codant pour elles |
WO2004001047A1 (fr) * | 2002-06-20 | 2003-12-31 | Yamanouchi Pharmaceutical Co., Ltd. | Nouveau promoteur |
NL1022371C2 (nl) * | 2003-01-13 | 2003-11-18 | Hoffmann La Roche | Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucle´nezuur samenstellingen. |
US20040219579A1 (en) * | 2003-02-19 | 2004-11-04 | Natasha Aziz | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer |
WO2005031359A2 (fr) * | 2003-09-27 | 2005-04-07 | Bayer Healthcare Ag | Agents diagnostiques et therapeutiques pour maladies associees a l'arginyl aminopeptidase (rnpep) |
WO2005040792A2 (fr) * | 2003-10-21 | 2005-05-06 | Bayer Healthcare Ag | Diagnostics et therapeutiques pour des maladies associees a l'arginyl aminopeptidase (aminopeptidase b)-de type 1 (rnpepl1) |
US7892750B1 (en) * | 2004-12-23 | 2011-02-22 | University Of Notre Dame Du Lac | Cathepsin E as a marker of colon cancer |
JP5532216B2 (ja) * | 2009-12-28 | 2014-06-25 | 国立大学法人埼玉大学 | 乳癌の検出方法 |
CN114075544A (zh) * | 2020-08-21 | 2022-02-22 | 复旦大学附属华山医院 | 基于超滤离心制备去泛素红细胞制品的方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0123928A2 (fr) * | 1983-03-31 | 1984-11-07 | Codon Genetic Engineering Laboratories | ADN recombinant codant pour un polypeptide présentant une activité de coagulation du lait |
WO1998031818A2 (fr) * | 1997-01-21 | 1998-07-23 | Human Genome Sciences, Inc. | Polypeptides semblables a tace ou a la matrilysime |
WO2000053774A2 (fr) * | 1999-03-08 | 2000-09-14 | Neurocrine Biosciences, Inc. | Metalloproteinases et leurs procedes d'utilisation |
WO2001036605A2 (fr) * | 1999-11-19 | 2001-05-25 | Millennium Pharmaceuticals, Inc. | 2786, nouvelle aminopeptidase humaine |
WO2001098468A2 (fr) * | 2000-06-16 | 2001-12-27 | Incyte Genomics, Inc. | Proteases |
-
2001
- 2001-05-04 CA CA002408105A patent/CA2408105A1/fr not_active Abandoned
- 2001-05-04 AU AU2001259473A patent/AU2001259473A1/en not_active Abandoned
- 2001-05-04 WO PCT/US2001/014431 patent/WO2001083782A2/fr not_active Application Discontinuation
- 2001-05-04 EP EP01933003A patent/EP1294901A2/fr not_active Withdrawn
- 2001-05-04 JP JP2001580389A patent/JP2004504812A/ja not_active Withdrawn
-
2003
- 2003-09-22 HK HK03106801.3A patent/HK1054571A1/zh unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0123928A2 (fr) * | 1983-03-31 | 1984-11-07 | Codon Genetic Engineering Laboratories | ADN recombinant codant pour un polypeptide présentant une activité de coagulation du lait |
WO1998031818A2 (fr) * | 1997-01-21 | 1998-07-23 | Human Genome Sciences, Inc. | Polypeptides semblables a tace ou a la matrilysime |
WO2000053774A2 (fr) * | 1999-03-08 | 2000-09-14 | Neurocrine Biosciences, Inc. | Metalloproteinases et leurs procedes d'utilisation |
WO2001036605A2 (fr) * | 1999-11-19 | 2001-05-25 | Millennium Pharmaceuticals, Inc. | 2786, nouvelle aminopeptidase humaine |
WO2001098468A2 (fr) * | 2000-06-16 | 2001-12-27 | Incyte Genomics, Inc. | Proteases |
Non-Patent Citations (4)
Title |
---|
DATABASE EMBL [online] 11 January 2000 (2000-01-11), "Homo sapiens matrix metalloprotease (ADAMTS1) mRNA", XP002210995, Database accession no. AF207664 * |
DATABASE EMBL [online] 18 October 2000 (2000-10-18), KRISTENSEN, T.: "Human aminopeptidase B cDNA cloning", XP002210996, Database accession no. AJ296161 * |
KAGEYAMA TAKASHI: "New World monkey pepsinogens A and C, and prochymosins. Purification, characterization of enzymatic properties, cDNA cloning, and molecular evolution.", JOURNAL OF BIOCHEMISTRY (TOKYO), vol. 127, no. 5, May 2000 (2000-05-01), pages 761 - 770, XP002195979, ISSN: 0021-924X * |
RAWLINGS NEIL D ET AL: "MEROPS: The peptidase database.", NUCLEIC ACIDS RESEARCH, vol. 27, no. 1, 1 January 1999 (1999-01-01), pages 325 - 331, XP002195980, ISSN: 0305-1048 * |
Also Published As
Publication number | Publication date |
---|---|
HK1054571A1 (zh) | 2003-12-05 |
JP2004504812A (ja) | 2004-02-19 |
AU2001259473A1 (en) | 2001-11-12 |
CA2408105A1 (fr) | 2001-11-08 |
EP1294901A2 (fr) | 2003-03-26 |
WO2001083782A2 (fr) | 2001-11-08 |
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