WO2001075121A3 - 16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations - Google Patents

16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations Download PDF

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Publication number
WO2001075121A3
WO2001075121A3 PCT/US2001/010273 US0110273W WO0175121A3 WO 2001075121 A3 WO2001075121 A3 WO 2001075121A3 US 0110273 W US0110273 W US 0110273W WO 0175121 A3 WO0175121 A3 WO 0175121A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
expression vectors
family member
provides isolated
Prior art date
Application number
PCT/US2001/010273
Other languages
English (en)
Other versions
WO2001075121A9 (fr
WO2001075121A2 (fr
Inventor
Rachel A Meyers
John J Hunter
Original Assignee
Millennium Pharm Inc
Rachel A Meyers
John J Hunter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Rachel A Meyers, John J Hunter filed Critical Millennium Pharm Inc
Priority to AU2001249649A priority Critical patent/AU2001249649A1/en
Priority to DE60138952T priority patent/DE60138952D1/de
Priority to AT01922897T priority patent/ATE433489T1/de
Priority to EP01922897A priority patent/EP1294899B3/fr
Publication of WO2001075121A2 publication Critical patent/WO2001075121A2/fr
Publication of WO2001075121A3 publication Critical patent/WO2001075121A3/fr
Publication of WO2001075121A9 publication Critical patent/WO2001075121A9/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention porte sur des molécules d'acide nucléique isolées, appelées molécules 16836, qui codent de nouveaux éléments de la phospholipase C. L'invention porte également sur des molécules d'acide nucléique antisens, des vecteurs d'expression de recombinaison contenant les molécules d'acide nucléique 16836, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits, et des animaux transgéniques dans lesquels a été introduit ou rompu le gène 16836. L'invention porte encore sur des protéines 16836 isolées, sur des protéines de fusion, sur des peptides antigéniques et des anticorps anti-16836, ainsi que sur des procédés de diagnostic utilisant les compositions précitées.
PCT/US2001/010273 2000-03-31 2001-03-30 16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations WO2001075121A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2001249649A AU2001249649A1 (en) 2000-03-31 2001-03-30 16836, a novel human phospholipase c family member and uses thereof
DE60138952T DE60138952D1 (de) 2000-03-31 2001-03-30 16836, ein mitglied der humanen phospholipase c familie und seine verwendungen
AT01922897T ATE433489T1 (de) 2000-03-31 2001-03-30 16836, ein mitglied der humanen phospholipase c familie und seine verwendungen
EP01922897A EP1294899B3 (fr) 2000-03-31 2001-03-30 16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19392100P 2000-03-31 2000-03-31
US60/193,921 2000-03-31

Publications (3)

Publication Number Publication Date
WO2001075121A2 WO2001075121A2 (fr) 2001-10-11
WO2001075121A3 true WO2001075121A3 (fr) 2002-04-25
WO2001075121A9 WO2001075121A9 (fr) 2002-05-30

Family

ID=22715571

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/010273 WO2001075121A2 (fr) 2000-03-31 2001-03-30 16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations

Country Status (7)

Country Link
US (1) US20010039331A1 (fr)
EP (1) EP1294899B3 (fr)
AT (1) ATE433489T1 (fr)
AU (1) AU2001249649A1 (fr)
DE (1) DE60138952D1 (fr)
ES (1) ES2328448T7 (fr)
WO (1) WO2001075121A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001270599A1 (en) * 2000-06-29 2002-01-08 Bayer Aktiengesellschaft Regulation of human phospholipase c-like enzyme
US6818420B2 (en) 2002-02-27 2004-11-16 Biosource International, Inc. Methods of using FET labeled oligonucleotides that include a 3′-5′ exonuclease resistant quencher domain and compositions for practicing the same
WO2003075006A1 (fr) * 2002-03-01 2003-09-12 Applera Corporation Determination de compatibilite d'un ensemble de modifications au moyen d'une chaine aminoacide
US7303914B2 (en) 2003-01-30 2007-12-04 Hongyang Wang Monoclonal antibody against human hepatoma and use thereof
US20050064436A1 (en) * 2003-09-24 2005-03-24 Barrett Michael T. Methods and compositions for identifying patient samples
EP3010514B1 (fr) * 2013-06-16 2021-01-20 National University Corporation Tokyo Medical and Dental University Acide nucléique antisens a double brin ayant un effet de saut d'exon

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0731164A1 (fr) * 1993-09-24 1996-09-11 Shionogi & Co., Ltd. PHOSPHOLIPASE C-$g(a) HUMAINE ET SEQUENCE D'ADN CODANT POUR CET ENZYME
WO1996032485A1 (fr) * 1995-04-10 1996-10-17 Incyte Pharmaceuticals, Inc. Homologue de phospholipase c
WO1998045436A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. Marqueurs secretes de sequence exprimee (sest)
WO1999058675A2 (fr) * 1998-05-14 1999-11-18 Chiron Corporation Genes humains et produits d'expression genique v
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»
EP1074617A2 (fr) * 1999-07-29 2001-02-07 Helix Research Institute Amorces pour la synthèse de cADN de pleine longueur et leur utilisation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0731164A1 (fr) * 1993-09-24 1996-09-11 Shionogi & Co., Ltd. PHOSPHOLIPASE C-$g(a) HUMAINE ET SEQUENCE D'ADN CODANT POUR CET ENZYME
WO1996032485A1 (fr) * 1995-04-10 1996-10-17 Incyte Pharmaceuticals, Inc. Homologue de phospholipase c
WO1998045436A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. Marqueurs secretes de sequence exprimee (sest)
WO1999058675A2 (fr) * 1998-05-14 1999-11-18 Chiron Corporation Genes humains et produits d'expression genique v
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»
EP1074617A2 (fr) * 1999-07-29 2001-02-07 Helix Research Institute Amorces pour la synthèse de cADN de pleine longueur et leur utilisation

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL SEQUENCE DATABASE Hinxton, UK; 10 February 2000 (2000-02-10), ASHWELL: "Human DNA sequence from clone RP11-162K11 on chromosome 10", XP002180627 *
DATABASE EMBL SEQUENCE DATABASE Hinxton, UK; 14 March 2000 (2000-03-14), REICHENSTEIN ET AL.: "Mus musculus phospholipase C-like protein mRNA, partial cds.", XP002180628 *
DATABASE EMBL SEQUENCE DATABASE Hinxton, UK; 2 January 2000 (2000-01-02), KAWASAKI ET AL.: "Homo sapiens pancreas-enriched phospholipase C mRNA, complete, cds.", XP002180626 *
DATABASE EMBL SEQUENCE DATABASE Hinxton, UK; 2 November 2000 (2000-11-02), LOPEZ ET AL.: "Homo sapiens phospholipase C epsilon mRNA partial cds.", XP002180633 *
DATABASE EMBL SEQUENCE DATABASE Hinxton, UK; 2 October 2000 (2000-10-02), SONG ET AL.: "Homo sapiens phosphoinositide phospholipase C PLC-epsilon mRNA, complete cds.", XP002180632 *
DATABASE EMBL SEQUENCE DATABASE HInxton, UK; 26 June 2001 (2001-06-26), OTA ET AL.: "Human protein sequence SEQ ID Nos. 14219 and 14220;", XP002180630 *
DATABASE EMBL SEQUENCE DATABSE Hinxton, UK; 23 May 2000 (2000-05-23), OHARA ET AL.: "Homo sapiens mRNA for KIAA1516 protein, partial cds.", XP002180631 *
DATABASE EMBL SEQUENCE DATABSE Hinxton, UK; 8 February 2001 (2001-02-08), SHIMKETS AND LEACH: "Human ORFX ORF1967 polynucleotide sequence SEQ ID No. 3933;", XP002180629 *
T. NAGASE ET AL.: "Prediction of the coding sequence of unidentified human genes XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro", DNA RESEARCH, vol. 7, April 2000 (2000-04-01), pages 143 - 150, XP000943428 *

Also Published As

Publication number Publication date
US20010039331A1 (en) 2001-11-08
WO2001075121A9 (fr) 2002-05-30
DE60138952D1 (de) 2011-04-28
EP1294899B3 (fr) 2011-07-06
ES2328448T7 (es) 2012-03-16
WO2001075121A2 (fr) 2001-10-11
ATE433489T1 (de) 2009-06-15
AU2001249649A1 (en) 2001-10-15
EP1294899B1 (fr) 2009-06-10
EP1294899A2 (fr) 2003-03-26
ES2328448T3 (es) 2009-11-13

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