WO2001074904A3 - G-protein coupled receptors and nucleic acids encoding same - Google Patents

G-protein coupled receptors and nucleic acids encoding same Download PDF

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Publication number
WO2001074904A3
WO2001074904A3 PCT/US2001/010241 US0110241W WO0174904A3 WO 2001074904 A3 WO2001074904 A3 WO 2001074904A3 US 0110241 W US0110241 W US 0110241W WO 0174904 A3 WO0174904 A3 WO 0174904A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
acids encoding
protein coupled
coupled receptors
encoding same
Prior art date
Application number
PCT/US2001/010241
Other languages
French (fr)
Other versions
WO2001074904A2 (en
Inventor
Kumud Majumder
Corine A M Vernet
Stacie J Casman
Adam R Wolenc
Steven K Spaderna
Muralidhara Padigaru
Vishnu Mishnu
Velizar T Tchernev
Kimberly A Spytek
Li Li
Jason C Baumgartner
Vladimir Y Gusev
Original Assignee
Curagen Corp
Kumud Majumder
Corine A M Vernet
Stacie J Casman
Adam R Wolenc
Steven K Spaderna
Muralidhara Padigaru
Vishnu Mishnu
Velizar T Tchernev
Kimberly A Spytek
Li Li
Jason C Baumgartner
Vladimir Y Gusev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Kumud Majumder, Corine A M Vernet, Stacie J Casman, Adam R Wolenc, Steven K Spaderna, Muralidhara Padigaru, Vishnu Mishnu, Velizar T Tchernev, Kimberly A Spytek, Li Li, Jason C Baumgartner, Vladimir Y Gusev filed Critical Curagen Corp
Priority to EP01930432A priority Critical patent/EP1274844A2/en
Priority to CA002404541A priority patent/CA2404541A1/en
Priority to JP2001572593A priority patent/JP2003534779A/en
Publication of WO2001074904A2 publication Critical patent/WO2001074904A2/en
Publication of WO2001074904A3 publication Critical patent/WO2001074904A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
PCT/US2001/010241 2000-03-31 2001-03-30 G-protein coupled receptors and nucleic acids encoding same WO2001074904A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01930432A EP1274844A2 (en) 2000-03-31 2001-03-30 G-protein coupled receptors and nucleic acids encoding same
CA002404541A CA2404541A1 (en) 2000-03-31 2001-03-30 G-protein coupled receptors and nucleic acids encoding same
JP2001572593A JP2003534779A (en) 2000-03-31 2001-03-30 G protein-coupled receptor and nucleic acid encoding the same

Applications Claiming Priority (38)

Application Number Priority Date Filing Date Title
US19366400P 2000-03-31 2000-03-31
US60/193,664 2000-03-31
US19461400P 2000-04-05 2000-04-05
US60/194,614 2000-04-05
US19506900P 2000-04-06 2000-04-06
US19506700P 2000-04-06 2000-04-06
US19506300P 2000-04-06 2000-04-06
US19506600P 2000-04-06 2000-04-06
US19506800P 2000-04-06 2000-04-06
US19551000P 2000-04-06 2000-04-06
US19507000P 2000-04-06 2000-04-06
US60/195,070 2000-04-06
US60/195,067 2000-04-06
US60/195,063 2000-04-06
US60/195,069 2000-04-06
US60/195,066 2000-04-06
US60/195,510 2000-04-06
US60/195,068 2000-04-06
US21985500P 2000-07-21 2000-07-21
US60/219,855 2000-07-21
US22128400P 2000-07-27 2000-07-27
US60/221,284 2000-07-27
US22132500P 2000-07-28 2000-07-28
US60/221,325 2000-07-28
US22458800P 2000-08-11 2000-08-11
US60/224,588 2000-08-11
US23961300P 2000-10-11 2000-10-11
US60/239,613 2000-10-11
US26250801P 2001-01-18 2001-01-18
US60/262,508 2001-01-18
US26343301P 2001-01-23 2001-01-23
US26360401P 2001-01-23 2001-01-23
US60/263,433 2001-01-23
US60/263,604 2001-01-23
US26516101P 2001-01-30 2001-01-30
US60/265,161 2001-01-30
US82317201A 2001-03-29 2001-03-29
US09/823,172 2001-03-29

Publications (2)

Publication Number Publication Date
WO2001074904A2 WO2001074904A2 (en) 2001-10-11
WO2001074904A3 true WO2001074904A3 (en) 2002-06-20

Family

ID=27586315

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/010241 WO2001074904A2 (en) 2000-03-31 2001-03-30 G-protein coupled receptors and nucleic acids encoding same

Country Status (4)

Country Link
EP (1) EP1274844A2 (en)
JP (1) JP2003534779A (en)
CA (1) CA2404541A1 (en)
WO (1) WO2001074904A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208280B2 (en) 1999-10-05 2007-04-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 101P3A41 useful in treatment and detection of cancer
US7361338B2 (en) 1999-10-05 2008-04-22 Agensys, Inc. Methods to inhibit growth of prostate cancer cells
US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
EP1272631A2 (en) * 2000-04-05 2003-01-08 Bayer Aktiengesellschaft Regulation of human hm74-like g protein coupled receptor
AU2002227445A1 (en) * 2000-12-18 2002-07-01 Curagen Corporation Proteins and nucleic acids encoding same
CA2438107A1 (en) * 2001-02-14 2002-10-24 Amgen, Inc. G-protein coupled receptor molecules and uses thereof
WO2002092842A2 (en) * 2001-05-15 2002-11-21 Agensys, Inc. Nucleic acids and corresponsing proteins entitled 101p3a11 or phor-1 useful in treatment and detection of cancer
US6902902B2 (en) 2001-11-27 2005-06-07 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
US7189524B1 (en) 2002-11-25 2007-03-13 Amgen, Inc. Receptor ligands and methods of modulating receptors
US7893197B2 (en) 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
GB201513921D0 (en) 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030406A1 (en) * 1995-03-30 1996-10-03 Human Genome Sciences, Inc. Human g-protein coupled receptors
EP0867508A2 (en) * 1997-03-28 1998-09-30 Smithkline Beecham Corporation Olfactory receptor of the 7-transmembrane receptor family - OLRCC15 receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001073029A2 (en) * 2000-03-27 2001-10-04 Pe Corporation (Ny) Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof
WO2001077320A2 (en) * 2000-04-05 2001-10-18 Bayer Aktiengesellschaft Regulation of human hm74-like g protein coupled receptor
WO2001087937A2 (en) * 2000-05-18 2001-11-22 Incyte Genomics, Inc. G-protein coupled receptors

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030406A1 (en) * 1995-03-30 1996-10-03 Human Genome Sciences, Inc. Human g-protein coupled receptors
EP0867508A2 (en) * 1997-03-28 1998-09-30 Smithkline Beecham Corporation Olfactory receptor of the 7-transmembrane receptor family - OLRCC15 receptor
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001073029A2 (en) * 2000-03-27 2001-10-04 Pe Corporation (Ny) Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof
WO2001077320A2 (en) * 2000-04-05 2001-10-18 Bayer Aktiengesellschaft Regulation of human hm74-like g protein coupled receptor
WO2001087937A2 (en) * 2000-05-18 2001-11-22 Incyte Genomics, Inc. G-protein coupled receptors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ROUQUIER S ET AL: "Distribution of olfactory receptor genes in the human genome", NATURE GENETICS, NEW YORK, NY, US, vol. 18, no. 3, March 1998 (1998-03-01), pages 243 - 250, XP002111208, ISSN: 1061-4036 *

Also Published As

Publication number Publication date
JP2003534779A (en) 2003-11-25
WO2001074904A2 (en) 2001-10-11
CA2404541A1 (en) 2001-10-11
EP1274844A2 (en) 2003-01-15

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