WO2001070171A1 - Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles - Google Patents

Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles Download PDF

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Publication number
WO2001070171A1
WO2001070171A1 PCT/IB2000/000341 IB0000341W WO0170171A1 WO 2001070171 A1 WO2001070171 A1 WO 2001070171A1 IB 0000341 W IB0000341 W IB 0000341W WO 0170171 A1 WO0170171 A1 WO 0170171A1
Authority
WO
WIPO (PCT)
Prior art keywords
filling machine
capsule
fact
capsule filling
bushing
Prior art date
Application number
PCT/IB2000/000341
Other languages
English (en)
Inventor
Libero Facchini
Original Assignee
B.L. Macchine Automatiche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B.L. Macchine Automatiche Spa filed Critical B.L. Macchine Automatiche Spa
Priority to AU2000233148A priority Critical patent/AU2000233148A1/en
Priority to PCT/IB2000/000341 priority patent/WO2001070171A1/fr
Priority to EP00911154A priority patent/EP1265581A1/fr
Publication of WO2001070171A1 publication Critical patent/WO2001070171A1/fr

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/30Devices or methods for controlling or determining the quantity or quality or the material fed or filled
    • B65B1/36Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods
    • B65B1/38Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods by pistons co-operating with measuring chambers
    • B65B1/385Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods by pistons co-operating with measuring chambers moving in an endless path
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations

Definitions

  • the present invention relates to the construction technique of capsule filling machines for powder, herbs, granules, pellets. INTERNATIONAL REFERENCE CLASS B65b.
  • capsule filling machines in which the dosing system is obtained by means of devices which enter the layer of products to be packed, withdraw a pre-set quantity of product and rise, coming out of the layer to introduce the dose in an empty capsule which is positioned over it
  • the problem to be solved is the realisation of an hermetic capsule filling machine in which the dosing devices are always inside the products to be packed, which can be treated even in minimum quantities distributed in layers having a reduced height.
  • Drawing no. 1 shows the partial radial section of a capsule filling machine which is equipped to produce capsules with powders or herbs. !t is possible to notice that the group to feed and dose powder or herbs is mainly composed of details nos. 1 , 2, 3, 4, 5 and 6 while the capsule feeding group is mainly composed by details nos. 7,8,9,10,11.
  • Drawing no. 1 shows the capsule feeder complete with the device to dispose the capsuie with the top cap up, before being introduced in the opening device.
  • Drawing no. 2 shows the phase in which the already oriented capsules are introduced in to line with the opening device.
  • Drawing no. 3 shows the capsule opening phase during which the bottom is separated from the upper covering.
  • the dosing operation is in preparation; during this phase the piston no. 4 and the dosing device no. 3 start to move downwards.
  • Drawing no. 4 shows the transferring of the first partial dose, which is introduced in the bushing no. 5 below; it is possible to observe that the dosing piston no. 4 and the dosing device no. 3 continue to move downwards.
  • Drawing no. 5 shows the transferring of the first partial dose while the piston no. 4 and dosing device no.
  • Drawing no. 6 shows the piston no. 4 and the dosing device no. 3 that start moving upward after having released the first dosing in the bushing no. 5 below.
  • Drawing no. 7 and drawing no. 8 show the carrying out of the second partial dosing.
  • Drawing no. 9 shows the final phase of the dosing, when ail partial doses are pressed on the lower contrast disc no. 8 by the piston no. 4.
  • Drawing no. 10 shows the positioning of the capsule bottom in line with the upper bushing no. 5.
  • Drawing no. 11 shows the starting phase of dose insertion in the capsule bottom
  • Drawing no. 12 shows the ending phase of dose insertion in the capsule bottom.
  • Drawing no. 13 shows the movement back of the capsule bottom, which has been filled with the dose, toward the closing device.
  • Drawing no. 14 shows the positioning of the full capsule bottom that is aligned with its own top cap.
  • Drawings nos. 15, 16, 17 and 18 show the closing and ejecting phases of the capsules at the end of the packing cycle and the capsule filling machine preparation to start a new working cycle.
  • Drawing no. 19 is a schematical representation of the five concentric circumferences (I; II; III; IV; V) along which the different operating devices are distributed.
  • Drawing no. 20 is a schematical representation of the product to be packed. It is possible to notice that in the left part there is an arrangement with dosing devices to pack powder or herbs, while in the right part there is an arrangement with aspirating dosing devices to pack micro-granules. It is possible to observe the central channel no. 12 for the products to be filled no. 2, which are pushed towards the peripherical parts of the rotating tower by the centrifugal force .
  • Drawing from no. 21 to no. 38 show the same schematised capsule filling machine equipped with modified dosing devices to fill capsules with micro-granules.
  • Drawing no. 39 shows a capsule which is still empty but closed.
  • Drawing no. 40 shows only its top cap.
  • Drawing no. 41 shows the capsule bottom without the top cap.
  • Drawing no. 42 shows the dose introduced inside the capsule bottom.
  • Drawing no. 43 shows the closed capsule containing the dose
  • VACUUM indicates the dosing piston to work with granules/pellets, which is equipped with the internal cannula for the VACUUM aspiration
  • 5 indicates the bushing in which the doses of the product to be packed are inserted
  • 6 indicates a contrast disc for the pressing of the doses
  • 11 indicates an aspirating bar to separate the empty capsule bottom from the capsule top cap
  • the field of protection of the present invention will include the capsule filling machines that can equipped with the different dosing devices to handle powder/herbs or granules/pellets, having the characteristics that have been described, illustrated and claimed afterwards.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Quality & Reliability (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne une remplisseuse dans laquelle les produits de remplissage des capsules arrivent de manière étanche depuis l"intérieur du tube tournant et sont poussés par la force centrifuge dans une zone de prélèvement des dispositifs de dosage. La couche de produit à conditionner, présente une hauteur minimale dans la zone de prélèvement ce qui permet d"effectuer le conditionnement même avec des quantités infimes de produit. En fonctionnement, les dispositifs de dosage sont plongés en continu dans la couche périphérique de prélèvement et n"en sortent pas, même pendant la phase de sortie.
PCT/IB2000/000341 2000-03-22 2000-03-22 Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles WO2001070171A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2000233148A AU2000233148A1 (en) 2000-03-22 2000-03-22 Capsules filling machine to pack powder, herbs, microgranules, pellets
PCT/IB2000/000341 WO2001070171A1 (fr) 2000-03-22 2000-03-22 Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles
EP00911154A EP1265581A1 (fr) 2000-03-22 2000-03-22 Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2000/000341 WO2001070171A1 (fr) 2000-03-22 2000-03-22 Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles

Publications (1)

Publication Number Publication Date
WO2001070171A1 true WO2001070171A1 (fr) 2001-09-27

Family

ID=11003898

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2000/000341 WO2001070171A1 (fr) 2000-03-22 2000-03-22 Remplisseuse de capsules utilisee pour conditionner de la poudre, des herbes, des micro-granules ou des pastilles

Country Status (3)

Country Link
EP (1) EP1265581A1 (fr)
AU (1) AU2000233148A1 (fr)
WO (1) WO2001070171A1 (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004014286A1 (fr) * 2002-08-08 2004-02-19 I.M.A. Industria Macchine Automatiche S.P.A. Machine de remplissage de capsules
US7210507B2 (en) 2002-05-13 2007-05-01 B.L. Macchine Automatiche S.P.A. Capsule filling machine
CN101962089A (zh) * 2010-10-11 2011-02-02 蓝星沈阳轻工机械设计研究所 一种灌装高度可调式液体定量灌装装置
CN102100638A (zh) * 2009-12-22 2011-06-22 Mg2有限公司 用于对胶囊填充药剂的间歇式旋转机器
CN102100637A (zh) * 2009-12-22 2011-06-22 Mg2有限公司 用于对胶囊填充药剂的间歇式旋转机器
CN102100639A (zh) * 2009-12-22 2011-06-22 Mg2有限公司 用于对胶囊填充药剂的间歇式旋转机器
ITBO20100203A1 (it) * 2010-04-02 2011-10-03 Mg 2 Srl Macchina per il riempimento di capsule con prodotti farmaceutici
ITBO20130178A1 (it) * 2013-04-19 2014-10-20 Mg 2 Srl Macchina rotativa continua per il riempimento di capsule con prodotti farmaceutici
US20150113917A1 (en) * 2012-05-08 2015-04-30 I.M.A. Industria Macchine Automatiche S.P.A. Apparatus for feeding capsules
ITUA20163077A1 (it) * 2016-05-02 2017-11-02 Mg 2 Srl Gruppo di alimentazione per il dosaggio di granuli, in particolare microgranuli, in capsule
CN114144153A (zh) * 2019-07-22 2022-03-04 I·M·A·工业机械自动装置股份公司 用于填充胶囊的机器和方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104287969B (zh) * 2014-09-27 2017-05-10 四川制药制剂有限公司 头孢克洛空心胶囊的定向装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882908A (en) * 1972-12-05 1975-05-13 Asea Ab Centrifugal machine for filling of powder capsules
US3921681A (en) * 1973-05-02 1975-11-25 Bosch Verpackungsmaschinen Apparatus for filling hard gelatin capsules or the like with powder
CH587152A5 (fr) * 1975-09-05 1977-04-29 Rottermann Robert
FR2502004A1 (fr) * 1981-03-18 1982-09-24 Bosch Gmbh Robert Machine a remplir des gelules dures de poudre et a les fermer, notamment dans l'industrie pharmaceutique
DE19618237C1 (de) * 1996-05-07 1997-08-21 Bosch Gmbh Robert Vorrichtung zum Abfüllen von Pulver in Hartgelatinekapseln oder dergleichen

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882908A (en) * 1972-12-05 1975-05-13 Asea Ab Centrifugal machine for filling of powder capsules
US3921681A (en) * 1973-05-02 1975-11-25 Bosch Verpackungsmaschinen Apparatus for filling hard gelatin capsules or the like with powder
CH587152A5 (fr) * 1975-09-05 1977-04-29 Rottermann Robert
FR2502004A1 (fr) * 1981-03-18 1982-09-24 Bosch Gmbh Robert Machine a remplir des gelules dures de poudre et a les fermer, notamment dans l'industrie pharmaceutique
DE19618237C1 (de) * 1996-05-07 1997-08-21 Bosch Gmbh Robert Vorrichtung zum Abfüllen von Pulver in Hartgelatinekapseln oder dergleichen

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7210507B2 (en) 2002-05-13 2007-05-01 B.L. Macchine Automatiche S.P.A. Capsule filling machine
CN100404014C (zh) * 2002-08-08 2008-07-23 I.M.A.工业机械自动装置股份公司 胶囊充填机
WO2004014286A1 (fr) * 2002-08-08 2004-02-19 I.M.A. Industria Macchine Automatiche S.P.A. Machine de remplissage de capsules
CN102100638A (zh) * 2009-12-22 2011-06-22 Mg2有限公司 用于对胶囊填充药剂的间歇式旋转机器
CN102100637A (zh) * 2009-12-22 2011-06-22 Mg2有限公司 用于对胶囊填充药剂的间歇式旋转机器
CN102100639A (zh) * 2009-12-22 2011-06-22 Mg2有限公司 用于对胶囊填充药剂的间歇式旋转机器
ITBO20100203A1 (it) * 2010-04-02 2011-10-03 Mg 2 Srl Macchina per il riempimento di capsule con prodotti farmaceutici
CN101962089A (zh) * 2010-10-11 2011-02-02 蓝星沈阳轻工机械设计研究所 一种灌装高度可调式液体定量灌装装置
US20150113917A1 (en) * 2012-05-08 2015-04-30 I.M.A. Industria Macchine Automatiche S.P.A. Apparatus for feeding capsules
ITBO20130178A1 (it) * 2013-04-19 2014-10-20 Mg 2 Srl Macchina rotativa continua per il riempimento di capsule con prodotti farmaceutici
US10023332B2 (en) 2013-04-19 2018-07-17 Mg2-S.R.L. Continuous rotary machine for filling capsules with pharmaceutical products
ITUA20163077A1 (it) * 2016-05-02 2017-11-02 Mg 2 Srl Gruppo di alimentazione per il dosaggio di granuli, in particolare microgranuli, in capsule
US10456331B2 (en) 2016-05-02 2019-10-29 Mg 2-S.R.L. Feeding assembly to fill capsules with granules, in particular microgranules
CN114144153A (zh) * 2019-07-22 2022-03-04 I·M·A·工业机械自动装置股份公司 用于填充胶囊的机器和方法
CN114144153B (zh) * 2019-07-22 2023-12-29 I·M·A·工业机械自动装置股份公司 用于填充胶囊的机器和方法
US11951076B2 (en) 2019-07-22 2024-04-09 I.M.A. Industria Macchine Automatiche S.P.A. Machine and method for filling capsules

Also Published As

Publication number Publication date
AU2000233148A1 (en) 2001-10-03
EP1265581A1 (fr) 2002-12-18

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