WO2001061360A3 - Identification of modulators of gpr31 activity - Google Patents
Identification of modulators of gpr31 activity Download PDFInfo
- Publication number
- WO2001061360A3 WO2001061360A3 PCT/GB2001/000693 GB0100693W WO0161360A3 WO 2001061360 A3 WO2001061360 A3 WO 2001061360A3 GB 0100693 W GB0100693 W GB 0100693W WO 0161360 A3 WO0161360 A3 WO 0161360A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gpr
- activity
- identification
- protein
- gpr31
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU33895/01A AU3389501A (en) | 2000-02-18 | 2001-02-19 | Assay |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0003898.4 | 2000-02-18 | ||
GBGB0003898.4A GB0003898D0 (en) | 2000-02-18 | 2000-02-18 | Assay |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001061360A2 WO2001061360A2 (en) | 2001-08-23 |
WO2001061360A3 true WO2001061360A3 (en) | 2002-03-28 |
Family
ID=9885980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2001/000693 WO2001061360A2 (en) | 2000-02-18 | 2001-02-19 | Identification of modulators of gpr31 activity |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU3389501A (en) |
GB (1) | GB0003898D0 (en) |
WO (1) | WO2001061360A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040254224A1 (en) * | 2001-04-11 | 2004-12-16 | Foord Steven Michael | Medicaments |
WO2005059561A2 (en) * | 2003-12-12 | 2005-06-30 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 31 (gpr31) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000022129A1 (en) * | 1998-10-13 | 2000-04-20 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human g protein-coupled receptors |
-
2000
- 2000-02-18 GB GBGB0003898.4A patent/GB0003898D0/en not_active Ceased
-
2001
- 2001-02-19 AU AU33895/01A patent/AU3389501A/en not_active Abandoned
- 2001-02-19 WO PCT/GB2001/000693 patent/WO2001061360A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000022129A1 (en) * | 1998-10-13 | 2000-04-20 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human g protein-coupled receptors |
Non-Patent Citations (4)
Title |
---|
DATABASE EMBL 21 August 2000 (2000-08-21), BEHAN D P ET AL: "Non-endogenous constitutively activated human G protein-coupled receptors, useful for identifying agonists for use as pharmaceutical agents", XP002174049 * |
SOEDER KURT J ET AL: "The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 17, 23 April 1999 (1999-04-23), pages 12017 - 12022, XP002174047, ISSN: 0021-9258 * |
WALSTON J ET AL: "The beta3-adrenergic receptor in the obesity and diabetes prone rhesus monkey is very similar to human and contains arginine at codon 64", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES,GB,ELSEVIER SCIENCE PUBLISHERS, BARKING, vol. 188, no. 2, 1 April 1997 (1997-04-01), pages 207 - 213, XP004059301, ISSN: 0378-1119 * |
ZINGONI ALESSANDRA ET AL: "Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor.", GENOMICS, vol. 42, no. 3, 1997, pages 519 - 523, XP002174048, ISSN: 0888-7543 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001061360A2 (en) | 2001-08-23 |
GB0003898D0 (en) | 2000-04-05 |
AU3389501A (en) | 2001-08-27 |
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