WO2001060985A3 - Compositions, methods and kits relating to uridine phosphorylase gene mutations - Google Patents
Compositions, methods and kits relating to uridine phosphorylase gene mutations Download PDFInfo
- Publication number
- WO2001060985A3 WO2001060985A3 PCT/US2001/004683 US0104683W WO0160985A3 WO 2001060985 A3 WO2001060985 A3 WO 2001060985A3 US 0104683 W US0104683 W US 0104683W WO 0160985 A3 WO0160985 A3 WO 0160985A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleotide
- uridine phosphorylase
- methods
- compositions
- mutations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001236990A AU2001236990A1 (en) | 2000-02-14 | 2001-02-14 | Compositions, methods and kits relating to uridine phosphorylase gene mutations |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18227300P | 2000-02-14 | 2000-02-14 | |
US60/182,273 | 2000-02-14 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2001060985A2 WO2001060985A2 (en) | 2001-08-23 |
WO2001060985A3 true WO2001060985A3 (en) | 2002-01-17 |
WO2001060985A9 WO2001060985A9 (en) | 2002-10-31 |
Family
ID=22667757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/004683 WO2001060985A2 (en) | 2000-02-14 | 2001-02-14 | Compositions, methods and kits relating to uridine phosphorylase gene mutations |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2001236990A1 (en) |
WO (1) | WO2001060985A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001169684A (en) | 1999-12-17 | 2001-06-26 | Taiho Yakuhin Kogyo Kk | Uridine phosphorylase-expression-deficient animal |
JP2007502119A (en) * | 2003-08-14 | 2007-02-08 | エクセリクシス, インク. | UPs as β-catenin pathway modifiers and methods of use |
CN111748537B (en) * | 2020-08-04 | 2021-11-26 | 浙江华睿生物技术有限公司 | Uridine phosphatase mutant and application thereof |
WO2022133289A2 (en) * | 2020-12-18 | 2022-06-23 | Codexis, Inc. | Engineered uridine phosphorylase variant enzymes |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5077280A (en) * | 1988-04-12 | 1991-12-31 | Brown University Research Foundation | Treatment of viral infections |
-
2001
- 2001-02-14 AU AU2001236990A patent/AU2001236990A1/en not_active Abandoned
- 2001-02-14 WO PCT/US2001/004683 patent/WO2001060985A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5077280A (en) * | 1988-04-12 | 1991-12-31 | Brown University Research Foundation | Treatment of viral infections |
Non-Patent Citations (4)
Title |
---|
CAO ET AL.: "Effects of a point mutation in the active site of uridine phosphorylase on its enzyme activity, kinetics and BAU inhibition", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, vol. 41, March 2000 (2000-03-01), pages 156, XP001010490 * |
WATANABE ET AL.: "Cloning and expression of human uridine phosphorylase", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 216, no. 1, 1995, pages 265 - 272, XP001010461 * |
WATANABE ET AL.: "Purification, cloning and expression of murine uridine phosphorylase", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 20, 1995, pages 12191 - 12196, XP001010484 * |
ZHANG ET AL.: "Uridine phosphorylase gene mutations in human breast cancers: PCR-SSCP determination", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, vol. 41, March 2000 (2000-03-01), pages 156 - 157, XP001010491 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001060985A9 (en) | 2002-10-31 |
WO2001060985A2 (en) | 2001-08-23 |
AU2001236990A1 (en) | 2001-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2002085940A3 (en) | New polynucleotides and polypeptides of the erythropoietin gene | |
EP1440981A3 (en) | Full-length human cdna | |
WO1999047669A3 (en) | Human nucleic acid sequences from tissue of breast tumors | |
WO2002077171A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
IL158415A0 (en) | NEW POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNalpha-17 GENE | |
WO2002079249A3 (en) | New polynucleotides and polypeptides of the ifn$g(a)-21 gene | |
WO2001060985A3 (en) | Compositions, methods and kits relating to uridine phosphorylase gene mutations | |
WO2002095067A3 (en) | INTERFERON α-14 POLYMORPHISM | |
WO2001072977A3 (en) | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof | |
WO2003000896A3 (en) | POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNα-5 GENE | |
WO2001092496A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
WO2002101048A3 (en) | NEW POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNα-7 GENE | |
EP1236800A3 (en) | Nucleic acids encoding interferon alpha 2, containing single nucleotide polymorphisms and methods of use thereof | |
BR0109258A (en) | Enzymes involved in triterpene synthesis | |
WO2002016567A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
WO2002083733A3 (en) | Polynucleotides and polypeptides of the ifnalpha-6 gene | |
WO2002053717A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
WO2002033058A3 (en) | Novel cysteine proteases and uses thereof | |
EP1201680A3 (en) | Tumor suppressor polypeptide issued from CHC1-L (chromosome condensation 1-like) | |
WO2002068617A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
WO2001090328A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
WO2002062845A3 (en) | Adhesion molecules | |
IL159384A0 (en) | Immunological binding molecules inhibiting the syncytial fusion of trophoblast cells | |
WO2003095612A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof | |
WO2002079431A3 (en) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
AK | Designated states |
Kind code of ref document: C2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: C2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
COP | Corrected version of pamphlet |
Free format text: PAGES 1/7-7/7, DRAWINGS, REPLACED BY NEW PAGES 1/7-7/7; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 Ref country code: DE Ref legal event code: 8642 |
|
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |