WO2001058914A3 - Haplotypes of the interleukin 15 gene - Google Patents

Haplotypes of the interleukin 15 gene Download PDF

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Publication number
WO2001058914A3
WO2001058914A3 PCT/US2001/004130 US0104130W WO0158914A3 WO 2001058914 A3 WO2001058914 A3 WO 2001058914A3 US 0104130 W US0104130 W US 0104130W WO 0158914 A3 WO0158914 A3 WO 0158914A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene
haplotypes
interleukin
polymorphisms
polynucleotides
Prior art date
Application number
PCT/US2001/004130
Other languages
French (fr)
Other versions
WO2001058914A2 (en
Inventor
Alison E Anastasio
Anne Chew
R Rex Denton
Krishnan Nandabalan
J Claiborne Stephens
Original Assignee
Genaissance Pharmaceuticals
Alison E Anastasio
Anne Chew
R Rex Denton
Krishnan Nandabalan
J Claiborne Stephens
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Alison E Anastasio, Anne Chew, R Rex Denton, Krishnan Nandabalan, J Claiborne Stephens filed Critical Genaissance Pharmaceuticals
Priority to AU2001239750A priority Critical patent/AU2001239750A1/en
Priority to PCT/US2001/025470 priority patent/WO2002063044A2/en
Publication of WO2001058914A2 publication Critical patent/WO2001058914A2/en
Publication of WO2001058914A3 publication Critical patent/WO2001058914A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Polynucleotides comprising one or more of 11 novel single nucleotide polymorphisms in the human Interleukin 15 (IL15) gene are described. Compositions and methods for detecting one or more of these polymorphisms are also disclosed. In addition, various genotypes and haplotypes for the IL15 gene that exist in the population are described.
PCT/US2001/004130 2000-02-08 2001-02-08 Haplotypes of the interleukin 15 gene WO2001058914A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001239750A AU2001239750A1 (en) 2000-02-08 2001-02-08 Haplotypes of the interleukin 15 gene
PCT/US2001/025470 WO2002063044A2 (en) 2001-02-08 2001-08-15 Haplotypes of the il15 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18105900P 2000-02-08 2000-02-08
US60/181,059 2000-02-08

Publications (2)

Publication Number Publication Date
WO2001058914A2 WO2001058914A2 (en) 2001-08-16
WO2001058914A3 true WO2001058914A3 (en) 2002-03-21

Family

ID=22662727

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/004130 WO2001058914A2 (en) 2000-02-08 2001-02-08 Haplotypes of the interleukin 15 gene

Country Status (2)

Country Link
AU (1) AU2001239750A1 (en)
WO (1) WO2001058914A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002063044A2 (en) * 2001-02-08 2002-08-15 Genaissance Pharmaceuticals, Inc. Haplotypes of the il15 gene
WO2008049620A1 (en) * 2006-10-25 2008-05-02 Hexal Gentech Forschungs Gmbh Semi-solid controlled release composition
EP3461331A1 (en) * 2013-10-15 2019-04-03 Regeneron Pharmaceuticals, Inc. Humanized il-15 animals

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 20 December 1996 (1996-12-20), KRAUSE ET AL.: "H. sapiens IL15 gene", XP002946162, Database accession no. X91233.1 *
KRAUSE ET AL.: "Genomic structure and chromosomal localization of the human interleukin 15 gene (IL-15)", CYTOKINE, vol. 8, no. 9, September 1996 (1996-09-01), pages 667 - 674, XP002946159 *

Also Published As

Publication number Publication date
WO2001058914A2 (en) 2001-08-16
AU2001239750A1 (en) 2001-08-20

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