WO2001051914A2 - Light photon detecting apparatus and a filter delivery and/or collection system therefor - Google Patents

Light photon detecting apparatus and a filter delivery and/or collection system therefor Download PDF

Info

Publication number
WO2001051914A2
WO2001051914A2 PCT/US2001/001241 US0101241W WO0151914A2 WO 2001051914 A2 WO2001051914 A2 WO 2001051914A2 US 0101241 W US0101241 W US 0101241W WO 0151914 A2 WO0151914 A2 WO 0151914A2
Authority
WO
WIPO (PCT)
Prior art keywords
filter
collection system
filter papers
detecting apparatus
light photon
Prior art date
Application number
PCT/US2001/001241
Other languages
French (fr)
Other versions
WO2001051914A9 (en
WO2001051914A3 (en
Inventor
Gavin B. J. Whitlock
Andrew J. Emery
Ivan Rogers
Doreen Whitlock
Original Assignee
Pall Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pall Corporation filed Critical Pall Corporation
Priority to AU2001232801A priority Critical patent/AU2001232801A1/en
Publication of WO2001051914A2 publication Critical patent/WO2001051914A2/en
Publication of WO2001051914A3 publication Critical patent/WO2001051914A3/en
Publication of WO2001051914A9 publication Critical patent/WO2001051914A9/en

Links

Classifications

    • G—PHYSICS
    • G07—CHECKING-DEVICES
    • G07F—COIN-FREED OR LIKE APPARATUS
    • G07F11/00—Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/02—Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines
    • G07F11/04—Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which magazines the articles are stored one vertically above the other
    • G07F11/06—Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which magazines the articles are stored one vertically above the other supported individually on pivotally-mounted flaps or shelves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G59/00—De-stacking of articles
    • B65G59/06—De-stacking from the bottom of the stack
    • B65G59/061—De-stacking from the bottom of the stack articles being separated substantially along the axis of the stack
    • B65G59/066—De-stacking from the bottom of the stack articles being separated substantially along the axis of the stack by means of rotary devices or endless elements
    • G—PHYSICS
    • G07—CHECKING-DEVICES
    • G07F—COIN-FREED OR LIKE APPARATUS
    • G07F11/00—Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/02—Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines
    • G07F11/04—Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which magazines the articles are stored one vertically above the other
    • G07F11/16—Delivery means
    • G07F11/24—Rotary or oscillatory members

Definitions

  • This invention relates to light photon detecting apparatus and a filter delivery and/or collection system therefor.
  • the present invention seeks to provide light photon detecting apparatus which will speeden up the checking process and in particular seeks to provide a filter delivery and/or collection system for such apparatus.
  • a filter delivery and/or collection system for use with light photon detecting apparatus, comprising an upstanding tube for receiving filter papers each held in an individual holder and two toothed wheels disposed adjacent to the lower end of the tube and angularly movable about horizontal or substantially horizontal axes to deliver filter papers to a surface below the tube or to receive filter papers and retain them in the tube.
  • light photon detecting apparatus comprising a filter paper delivery system ⁇ for delivering filter papers onto an indexable support surface, an impregnating device for impregnating the filter papers with a sample to be checked, an injection device for injecting reagents onto the filter papers, one or more light photon detectors for detecting light photons emitted from the reagent injected samples, and a filter paper collection system for collecting filter papers from the suppo ⁇ surface.
  • Figure 1 is a fragmentary, diagrammatic, perspective view of one embodiment of a filter delivery and/or collection system according to the first aspect of the invention
  • Figure 2 is a diagrammatic sectional view through the filter delivery and/or collection system shown in Figure 1 .
  • Figure 3 is a schematic plan view of one embodiment of light photon detecting apparatus according to the second aspect of the invention.
  • the filter delivery and/or collection system shown therein is chiefly intended for use with light photon detecting apparatus of the type shown schematically in Figure 3.
  • the delivery and/or collection system comprises a plurality of upstanding tubes 10, typically four in number, spaced apart above a circular suppo ⁇ surface 11.
  • the delivery and/or collection system also comprises two toothed wheels 12 mounted immediately below each tube '10.
  • the toothed wheels are diametrically opposed to one another with respect to each tube 10 and are angularly movable about respective horizontal axes which are parallel to one another.
  • the delivery system in particular also includes a mechanism (not shown) fop indexing the two wheels 12 in synchronism with one another and a control circuit (also not shown) for indexing the wheels 12 as and when required.
  • each tube When used as a filter delivery system, each tube contains a stack of sterile filter papers 13 each of which is held in an individual holder 14.
  • Each holder 14 comprises two annular parts 15 and 16 and the filter paper 13 is secured between the two parts.
  • the external diameter of the part 15 is smaller than the external diameter of the part 16 so that when the holders 14 are stacked one upon another an annular recess is provided between the larger diameter parts 16 of two adjacent holders 14 for receiving teeth of the toothed whe s 12.
  • the two toothed wheels 12 When serving as a filter delivery system, the two toothed wheels 12 are indexed in opposite angular directions and, as shown in Figure 2, the left hand wheel is indexed in a clockwise direction and the right hand wheel is indexed in a counter clockwi ⁇ direction. This will cause a filter paper 13 together with its holder 14 to drop onto the circular supporting surface 11.
  • the tubes 10, when full of filter papers 13, can be provided with removable seals at their lower ends.
  • the filter paper 13 and holder 14 are raised above the supporting suiface 11 by a plunger or ram (not shown) mounted in the supporting surface 11.
  • the toothed wheels 12 will simply operate as ratchets or can be driven in synchronism with the rising plunger or ram.
  • FIG. 3 there is shown therein light photon detecting apparatus comprising a circular carousel 20 which can be indexed by a drive unit (not shown).
  • the apparatus has five stations.
  • a filter paper delivery system 21 which may be similar to that described with reference to Figures 1 and 2.
  • an impregnating device 22 for impregnating the filter papers with a water sample or an air sample.
  • an injection device 23 for injecting reagents such as, for example, detergent for cell disruption and luciferin-luciferase for reaction with released ATP molecules and/or other chemicals as appropriate for the test to be carried out.
  • a multiple light photon detector or a plurality of single photon detectors 24 the design of which can be based on the design of the lighi photon detector described in GB-A-22i8803, for detecting light photons emitted from the reagent injected samples.
  • a filter paper collection- system the design of which can be based on the design of the lighi photon detector described in GB-A-22i8803, for detecting light photons emitted from the reagent injected samples.
  • the tubes 10 of the filter delivery and collection system may be removable from their positions above the carousel 20 so that empty tubes from the delivery system can be used in the collection system.
  • This apparatus will allow continuous monitoring of samples with time intervals regulated by software. It also provides a facility to carry out comparative tests, simultaneously and or replicates of the same test.

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A filter delivery and/or collection system for use with light photon detecting apparatus, comptises an upstanding tube (10) for receiving filter paper (13) each held in an individual holder (14) and two toothed wheels (12) angularly moveable about horizontal or substantially horizontal axes to deliver filter papers to a surface (11) below the tube or to receive filter paper and retain them in the tube. Light photon detecting apparatus including filter paper delivery and/or collection systems as described is also disclosed.

Description

-l- LIGHT PHOTON DETECTING APPARATUS AND A
FILTER DELIVERY AND/OR COLLECTION SYSTEM THEREFOR
This invention relates to light photon detecting apparatus and a filter delivery and/or collection system therefor.
It is known to use light photon detecting apparatus, such as is, for example, described in GB-A-2218803, to check for contamination by bacteria. The known apparatus can only check a singl: sample at a time and the process of checking a large number of samples is slow.
The present invention seeks to provide light photon detecting apparatus which will speeden up the checking process and in particular seeks to provide a filter delivery and/or collection system for such apparatus.
According to a first aspect of the invention there is provided a filter delivery and/or collection system for use with light photon detecting apparatus, comprising an upstanding tube for receiving filter papers each held in an individual holder and two toothed wheels disposed adjacent to the lower end of the tube and angularly movable about horizontal or substantially horizontal axes to deliver filter papers to a surface below the tube or to receive filter papers and retain them in the tube.
Preferred and/or optional features of the first aspect of the invention are set forth in claims 2 to 4.
According to a seco d aspect of the invention there is provided light photon detecting apparatus comprising a filter paper delivery system^ for delivering filter papers onto an indexable support surface, an impregnating device for impregnating the filter papers with a sample to be checked, an injection device for injecting reagents onto the filter papers, one or more light photon detectors for detecting light photons emitted from the reagent injected samples, and a filter paper collection system for collecting filter papers from the suppoπ surface.
Preferred and/or optional features of the second aspect of the invention are set out in claims 7 and 8.
The invention will now be more particularly described, by way of example, with reference to the accompanying drawings, in which:
Figure 1 is a fragmentary, diagrammatic, perspective view of one embodiment of a filter delivery and/or collection system according to the first aspect of the invention,
Figure 2 is a diagrammatic sectional view through the filter delivery and/or collection system shown in Figure 1 , and
Figure 3 is a schematic plan view of one embodiment of light photon detecting apparatus according to the second aspect of the invention.
Referring firstly to Figures 1 and 2 of the drawings, the filter delivery and/or collection system shown therein is chiefly intended for use with light photon detecting apparatus of the type shown schematically in Figure 3.
The delivery and/or collection system comprises a plurality of upstanding tubes 10, typically four in number, spaced apart above a circular suppoπ surface 11. The delivery and/or collection system also comprises two toothed wheels 12 mounted immediately below each tube '10. The toothed wheels are diametrically opposed to one another with respect to each tube 10 and are angularly movable about respective horizontal axes which are parallel to one another. The delivery system in particular also includes a mechanism (not shown) fop indexing the two wheels 12 in synchronism with one another and a control circuit (also not shown) for indexing the wheels 12 as and when required.
When used as a filter delivery system, each tube contains a stack of sterile filter papers 13 each of which is held in an individual holder 14. Each holder 14 comprises two annular parts 15 and 16 and the filter paper 13 is secured between the two parts. The external diameter of the part 15 is smaller than the external diameter of the part 16 so that when the holders 14 are stacked one upon another an annular recess is provided between the larger diameter parts 16 of two adjacent holders 14 for receiving teeth of the toothed whe s 12. When serving as a filter delivery system, the two toothed wheels 12 are indexed in opposite angular directions and, as shown in Figure 2, the left hand wheel is indexed in a clockwise direction and the right hand wheel is indexed in a counter clockwi≤≥ direction. This will cause a filter paper 13 together with its holder 14 to drop onto the circular supporting surface 11.
The tubes 10, when full of filter papers 13, can be provided with removable seals at their lower ends.
When used as a filter collection system, the filter paper 13 and holder 14 are raised above the supporting suiface 11 by a plunger or ram (not shown) mounted in the supporting surface 11. In this case, the toothed wheels 12 will simply operate as ratchets or can be driven in synchronism with the rising plunger or ram.
Referring now to Figure 3, there is shown therein light photon detecting apparatus comprising a circular carousel 20 which can be indexed by a drive unit (not shown). The apparatus has five stations. In one station, there is provided a filter paper delivery system 21 which may be similar to that described with reference to Figures 1 and 2. At the next sration, there is an impregnating device 22 for impregnating the filter papers with a water sample or an air sample. At the next station, there is an injection device 23 for injecting reagents such as, for example, detergent for cell disruption and luciferin-luciferase for reaction with released ATP molecules and/or other chemicals as appropriate for the test to be carried out. At the next station, there is a multiple light photon detector or a plurality of single photon detectors 24, the design of which can be based on the design of the lighi photon detector described in GB-A-22i8803, for detecting light photons emitted from the reagent injected samples. At the final station, there is a filter paper collection- system
25, which may be similar to that described with reference to Figures 1 and 2 for collecting used filter papers for autoclaving.
The tubes 10 of the filter delivery and collection system may be removable from their positions above the carousel 20 so that empty tubes from the delivery system can be used in the collection system.
This apparatus will allow continuous monitoring of samples with time intervals regulated by software. It also provides a facility to carry out comparative tests, simultaneously and or replicates of the same test.

Claims

1. A filter delivery and/or collection system for use with light photon detecting apparatus, comprising an upstanding tube for receiving filter papers each held in an individual holder and two toothed wheels disposed adjacent to the lower end of the rube and angularly movable about horizontal or substantially horizontal axes to deliver filter papers to a surface below the tube or to receive filter papers and retain them in the tube.
2. A system as claimed in claim 1, in combination with a plurality of filter papers each in an individual holder.
3. A system as claimed in claim 2, wherein the holders each comprise two annular parts with a filter paper secured therebetween, one of the two parts having a smaller external dimension than the other so that when the holders are stacked one upon another a space is provided between the larger dimension pans of two adjacent holders for receiving teeth of the toothed wheels.
4. A system as claimed in any one of the preceding claims, comprising a plurality of tubes for delivering and/or collecting a plurality of filter papers.
5. A filter delivery and/or collection system substantially as hereinbefore described with reference to the accompanying drawings.
6 Light photon detecting apparatus comprising a filter paper deliver}' system for delivering filter papers onto a support surface, an impregnating device for impregnating the filter papers to a sample to be checked, an injection device for injecting reagents onto the filter papers, one or more light photon detectors for detecting light photons emitted from the reagent injected samples, and a filter paper collection system for collecting filter papers from the support surface.
7. Apparatus as claimed in claim 6, further comprising means for indexing the support surface.
8. Apparatus as claimed in claim 6 or claim 7, wherein the filter paper delivery system and/or the filter paper collection system is as claimed in any one of claims 1 to 5.
9. Light photon detecting apparatus substantially as hereinbefore described with reference to the accompanying drawings.
PCT/US2001/001241 2000-01-14 2001-01-16 Light photon detecting apparatus and a filter delivery and/or collection system therefor WO2001051914A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001232801A AU2001232801A1 (en) 2000-01-14 2001-01-16 Light photon detecting apparatus and a filter delivery and/or collection system therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0000693A GB2358183A (en) 2000-01-14 2000-01-14 Light photon detecting apparatus and a filter and/or collection system therefor
GB0000693.2 2000-01-14

Publications (3)

Publication Number Publication Date
WO2001051914A2 true WO2001051914A2 (en) 2001-07-19
WO2001051914A3 WO2001051914A3 (en) 2002-03-14
WO2001051914A9 WO2001051914A9 (en) 2002-08-08

Family

ID=9883590

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/001241 WO2001051914A2 (en) 2000-01-14 2001-01-16 Light photon detecting apparatus and a filter delivery and/or collection system therefor

Country Status (3)

Country Link
AU (1) AU2001232801A1 (en)
GB (1) GB2358183A (en)
WO (1) WO2001051914A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117446415A (en) * 2023-12-22 2024-01-26 湖南艾荻迩医疗科技有限公司 Test paper conveying device, analyzer and nutrition monitoring system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767189A (en) * 1971-08-16 1973-10-23 Sig Schweiz Industrieges Device for substantially relieving in an upright stack of sheet-like articles the lowermost article from the weight of the articles above the same
EP0567067A1 (en) * 1992-04-20 1993-10-27 Fuji Photo Film Co., Ltd. Cartridge for storing dry analytical film slides
DE4218202A1 (en) * 1992-06-03 1993-12-09 Kolbus Gmbh & Co Kg Continuously sorting out individual sheets from stacking magazine - involves cogged rotatable restraints acting on upper stack part and supports for lower stack part coupled to brake acting on restraints
EP0583078A2 (en) * 1992-07-14 1994-02-16 Wallac Oy Method and apparatus for handling samples

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB653623A (en) * 1945-05-11 1951-05-23 Mills Ind Inc Improvements in or relating to a machine for vending bottles or similar articles
US3455484A (en) * 1967-09-08 1969-07-15 Illinois Tool Works Container dispensing apparatus
SE435964B (en) * 1983-05-03 1984-10-29 Philips Norden Ab GEAR WHEEL DEFINITION DEVICE AND CONTAINER FOR RADAR REMOTE STRAPS AND LIKE
GB8515235D0 (en) * 1985-06-15 1985-07-17 Sankey Vending Ltd Article release apparatus
FR2700750B1 (en) * 1993-01-27 1995-04-07 Fournier Sca Laboratoires Blister counting and distribution device.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767189A (en) * 1971-08-16 1973-10-23 Sig Schweiz Industrieges Device for substantially relieving in an upright stack of sheet-like articles the lowermost article from the weight of the articles above the same
EP0567067A1 (en) * 1992-04-20 1993-10-27 Fuji Photo Film Co., Ltd. Cartridge for storing dry analytical film slides
DE4218202A1 (en) * 1992-06-03 1993-12-09 Kolbus Gmbh & Co Kg Continuously sorting out individual sheets from stacking magazine - involves cogged rotatable restraints acting on upper stack part and supports for lower stack part coupled to brake acting on restraints
EP0583078A2 (en) * 1992-07-14 1994-02-16 Wallac Oy Method and apparatus for handling samples

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117446415A (en) * 2023-12-22 2024-01-26 湖南艾荻迩医疗科技有限公司 Test paper conveying device, analyzer and nutrition monitoring system
CN117446415B (en) * 2023-12-22 2024-03-15 湖南艾荻迩医疗科技有限公司 Test paper conveying device, analyzer and nutrition monitoring system

Also Published As

Publication number Publication date
AU2001232801A1 (en) 2001-07-24
GB0000693D0 (en) 2000-03-08
WO2001051914A9 (en) 2002-08-08
WO2001051914A3 (en) 2002-03-14
GB2358183A (en) 2001-07-18

Similar Documents

Publication Publication Date Title
CN101332439B (en) Automatic liquor removing workstation
JP6743204B2 (en) Storage and supply of container holders
EP1305638B1 (en) Workstation for integrating automated chemical analyzers
EP1721171B1 (en) Magnetically attractive specimen-container rack for automated clinical instrument
EP0628824B1 (en) Transport system for fluid analysis instrument
AU672127B2 (en) Automated chemical analyzer with apparatus and method for conveying and temporary storage of sample tubes
EP0902290B1 (en) Sample handling system for automatic analysers
US8187535B2 (en) Robotic handling system and method with independently operable detachable tools
EP0159346B1 (en) Cassette for supporting test tubes of different diameters and/or lengths
EP3919915A1 (en) Sample test automation system
WO2008097892A2 (en) Apparatus and methods for dispensing sample holders
CA3168793A1 (en) Autosamplers and analytic systems and methods including same
WO2001036981A1 (en) Analyzer having a rotatable sample rack carrier
HU229210B1 (en) Method and automatic device for in vitro diagnostic tests of blood clotting
US9541566B2 (en) Accommodating magazine
WO2001051914A2 (en) Light photon detecting apparatus and a filter delivery and/or collection system therefor
CN101294975B (en) Grouping toxicology analyzer
EP3820611A1 (en) Reagent storage devices and methods for same
EP2598891B1 (en) System for the analysis of samples
JPS6385459A (en) Automatic analyzer
WO1995033193A1 (en) Universal stripper plate
CN211374795U (en) Module assembling type carrier frame device
CN112961769A (en) Single-channel single-cell nucleic acid processing instrument
CN220508950U (en) Sample pipe diameter distinguishing device, sample loading mechanism and assembly line
JPS6385457A (en) Automatic analyzer for plural items

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

AK Designated states

Kind code of ref document: C2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGES 1/3-3/3, DRAWINGS, REPLACED BY NEW PAGES 1/2-2/2; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

WWE Wipo information: entry into national phase

Ref document number: 152776

Country of ref document: IL

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase in:

Ref country code: JP