WO2001042774A3 - Capteur potentiometrique - Google Patents

Capteur potentiometrique Download PDF

Info

Publication number
WO2001042774A3
WO2001042774A3 PCT/GB2000/004711 GB0004711W WO0142774A3 WO 2001042774 A3 WO2001042774 A3 WO 2001042774A3 GB 0004711 W GB0004711 W GB 0004711W WO 0142774 A3 WO0142774 A3 WO 0142774A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion
flow channel
analyte ions
sample solution
substrate chip
Prior art date
Application number
PCT/GB2000/004711
Other languages
English (en)
Other versions
WO2001042774A2 (fr
Inventor
Andreas Manz
Ratna Tantra
Original Assignee
Imperial College
Andreas Manz
Ratna Tantra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial College, Andreas Manz, Ratna Tantra filed Critical Imperial College
Priority to EP00985509A priority Critical patent/EP1238269A2/fr
Priority to US10/148,969 priority patent/US20030112013A1/en
Publication of WO2001042774A2 publication Critical patent/WO2001042774A2/fr
Publication of WO2001042774A3 publication Critical patent/WO2001042774A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/4035—Combination of a single ion-sensing electrode and a single reference electrode
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/4473—Arrangements for investigating the separated zones, e.g. localising zones by electric means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La présente invention concerne un capteur potentiométrique micropréfabriqué et un procédé de mesure de l"activité des ions à analyser dans une solution échantillon, le capteur comportant: une puce substrat, un canal d"écoulement délimité par la puce substrat à travers duquel les ions d"analyse de la solution échantillon sont entraînés; au moins une électrode de sélection d"ions comprenant une enceinte délimitée par la puce substrat et comportant un orifice en communication avec le canal d"écoulement, une membrane de sélection d"ions disposée dans l"enceinte, et un élément conducteur présentant une configuration telle qu"en fonctionnement il soit en liaison électrique avec la membrane de sélection d"ions ; une électrode de référence présentant une configuration telle qu"en fonctionnement elle se trouve en liaison électrique avec le canal d"écoulement; ainsi, lorsque les ions d"analyse sont entraînés à travers le canal d"écoulement, une force électromotrice se développe entre ladite au moins une électrode de sélection d"ions et l"électrode de référence qui représente l"activité des ions d"analyse.
PCT/GB2000/004711 1999-12-08 2000-12-08 Capteur potentiometrique WO2001042774A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00985509A EP1238269A2 (fr) 1999-12-08 2000-12-08 Capteur potentiometrique
US10/148,969 US20030112013A1 (en) 1999-12-08 2000-12-08 Potentiometric sensor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9929069.4A GB9929069D0 (en) 1999-12-08 1999-12-08 Potentiometric sensor
GB9929069.4 1999-12-08

Publications (2)

Publication Number Publication Date
WO2001042774A2 WO2001042774A2 (fr) 2001-06-14
WO2001042774A3 true WO2001042774A3 (fr) 2001-12-27

Family

ID=10865966

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/004711 WO2001042774A2 (fr) 1999-12-08 2000-12-08 Capteur potentiometrique

Country Status (3)

Country Link
EP (1) EP1238269A2 (fr)
GB (1) GB9929069D0 (fr)
WO (1) WO2001042774A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1493487A1 (fr) * 2001-06-28 2005-01-05 Agilent Technologies, Inc. Système microfluidique avec régulation du courant ESI résiduel
NL1021269C2 (nl) * 2002-08-14 2004-02-17 Lionix B V Elektrodesysteem en werkwijze voor het aanleggen van elektrische spanningen en het teweegbrengen van elektrische stromen.
DE102017109225A1 (de) * 2017-04-28 2018-10-31 Testo SE & Co. KGaA Messanordnung zum Vermessen von Flüssigkeiten

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4314755A1 (de) * 1993-05-05 1994-11-10 Meinhard Prof Dr Knoll Kapillarelektrophoretisches Trennverfahren sowie Vorrichtung zur Durchführung von chemischen und biochemischen Analysen
DE4408352A1 (de) * 1994-03-12 1995-09-14 Meinhard Prof Dr Knoll Miniaturisierte Durchflußmeßkammer mit integrierten Chemo- und Biosensorelementen sowie Verfahren zu ihrer Herstellung
WO1998032008A1 (fr) * 1997-01-20 1998-07-23 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Cellule electrochimique a flux continu
WO1998049549A1 (fr) * 1997-04-30 1998-11-05 Orion Research, Inc. Systeme de separation par electrophorese capillaire

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4314755A1 (de) * 1993-05-05 1994-11-10 Meinhard Prof Dr Knoll Kapillarelektrophoretisches Trennverfahren sowie Vorrichtung zur Durchführung von chemischen und biochemischen Analysen
DE4408352A1 (de) * 1994-03-12 1995-09-14 Meinhard Prof Dr Knoll Miniaturisierte Durchflußmeßkammer mit integrierten Chemo- und Biosensorelementen sowie Verfahren zu ihrer Herstellung
WO1998032008A1 (fr) * 1997-01-20 1998-07-23 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Cellule electrochimique a flux continu
WO1998049549A1 (fr) * 1997-04-30 1998-11-05 Orion Research, Inc. Systeme de separation par electrophorese capillaire

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARQUINT P ET AL: "MICROMACHINED ANALYZERS ON A SILICON CHIP", CLINICAL CHEMISTRY,US,AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY. WINSTON, vol. 40, no. 9, 1 September 1994 (1994-09-01), pages 1805 - 1809, XP000444697, ISSN: 0009-9147 *
SHUICHI SHOJI ET AL: "MICRO FLOW CELL FOR BLOOD GAS ANALYSIS REALIZING VERY SMALL SAMPLE VOLUME*", SENSORS AND ACTUATORS B,CH,ELSEVIER SEQUOIA S.A., LAUSANNE, vol. B08, no. 2, 1 May 1992 (1992-05-01), pages 205 - 208, XP000286957, ISSN: 0925-4005 *

Also Published As

Publication number Publication date
WO2001042774A2 (fr) 2001-06-14
GB9929069D0 (en) 2000-02-02
EP1238269A2 (fr) 2002-09-11

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