WO2001040464A8 - Interleukin-1-receptor associated kinase-3 (irak3) and its use in promotion or inhibition of angiogenesis and cardiovascularization - Google Patents
Interleukin-1-receptor associated kinase-3 (irak3) and its use in promotion or inhibition of angiogenesis and cardiovascularizationInfo
- Publication number
- WO2001040464A8 WO2001040464A8 PCT/US2000/022031 US0022031W WO0140464A8 WO 2001040464 A8 WO2001040464 A8 WO 2001040464A8 US 0022031 W US0022031 W US 0022031W WO 0140464 A8 WO0140464 A8 WO 0140464A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptides
- present
- cardiovascularization
- compositions
- angiogenesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10041—Use of virus, viral particle or viral elements as a vector
- C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (251)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU69018/00A AU6901800A (en) | 1999-11-30 | 2000-08-11 | Interleukin-1-receptor associated kinase-3 (irak3) and its use in promotion or inhibition of angiogenesis and cardiovascularization |
EP10005292A EP2228446A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptieds and nucleic acids encoding the same |
EP06000582A EP1666495A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002490853A CA2490853A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA2709291A CA2709291A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP05025102A EP1672070A3 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000589A EP1661997A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000581A EP1666494A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000586A EP1688497A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002492070A CA2492070A1 (en) | 1999-12-01 | 2000-12-01 | Lung tumor marker pro4329 polypeptides and nucleic acids encoding the same |
EP06000585A EP1661996A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002491610A CA2491610A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002496312A CA2496312A1 (en) | 1999-12-01 | 2000-12-01 | Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same |
EP00983846A EP1250426A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding same |
CA002494705A CA2494705A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AU20554/01A AU2055401A (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2001542531A JP2004522404A (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding them |
PCT/US2000/032678 WO2001040466A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000588A EP1690873A3 (en) | 1999-12-01 | 2000-12-01 | Composition and methods for the diagnosis of tumours |
CA002491258A CA2491258A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000584A EP1669371A3 (en) | 1999-12-01 | 2000-12-01 | Composition and methods for the diagnosis of tumours |
CA002491433A CA2491433A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002391455A CA2391455A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002492049A CA2492049A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA002490909A CA2490909A1 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP06000587A EP1690872A3 (en) | 1999-12-01 | 2000-12-01 | Composition and methods for the diagnosis of tumours |
EP06000583A EP1686134A3 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/941,992 US20030082546A1 (en) | 1996-11-06 | 2001-08-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,748 US20030069403A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,163 US20020132253A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,442 US20020132252A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,854 US20030059780A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,427 US20030073809A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/992,598 US6956108B2 (en) | 1997-06-16 | 2001-11-14 | PRO1184 antibodies |
US09/990,438 US20030027754A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,440 US20030060407A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/992,521 US20030083461A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,444 US6930170B2 (en) | 1997-06-16 | 2001-11-14 | PRO1184 polypeptides |
US09/991,073 US20020127576A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,443 US20030054987A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,583 US7074897B2 (en) | 1997-06-16 | 2001-11-14 | Pro943 polypeptides |
US09/993,469 US20030068623A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,667 US20030022187A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,562 US20030027985A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,436 US20020198148A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/993,687 US20020198149A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,711 US20030032023A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,456 US20020137890A1 (en) | 1997-03-31 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,726 US20030054359A1 (en) | 1997-06-16 | 2001-11-14 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,601 US7189814B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,349 US7034106B2 (en) | 1997-06-16 | 2001-11-15 | Pro1159 polypeptides |
US09/997,529 US20030134284A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,614 US20030124531A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,641 US20030224358A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,585 US7166282B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,683 US20030059783A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,514 US7019116B2 (en) | 1997-06-16 | 2001-11-15 | PRO 1387 polypeptides |
US09/997,542 US20030068647A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/998,041 US7309775B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,384 US7119177B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,666 US7244816B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,601 US20030054404A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,384 US20030087305A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,641 US7112656B2 (en) | 1997-06-16 | 2001-11-15 | PRO1312 polypeptides |
US09/998,156 US20030044806A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,428 US20030027162A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,440 US20030059833A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,529 US7309761B2 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,653 US7034122B2 (en) | 1997-06-16 | 2001-11-15 | Antibodies to PRO1159 polypeptides |
US10/002,796 US20030032057A1 (en) | 1997-08-26 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,857 US20030064375A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,559 US20030054403A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,628 US20030059782A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,666 US20030027163A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/998,041 US20030119001A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,573 US20030049682A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,585 US20030119055A1 (en) | 1997-06-16 | 2001-11-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/997,333 US6953836B2 (en) | 1997-06-16 | 2001-11-15 | PRO844 polypeptides |
US09/991,150 US20030194760A1 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,441 US7041804B2 (en) | 1997-06-16 | 2001-11-16 | Antibodies to PRO1387 polypeptides |
US09/991,181 US6913919B2 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/990,437 US20030045463A1 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/991,157 US7101687B2 (en) | 1997-06-16 | 2001-11-16 | Nucleic acids encoding PRO943 |
US09/991,172 US20030050457A1 (en) | 1997-06-16 | 2001-11-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,328 US7056736B2 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,732 US7037679B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acids encoding PRO1184 polypeptides |
US09/989,279 US7083978B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acid encoding PRO1111 polypeptides |
US09/989,723 US20020072092A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,734 US7491529B2 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,729 US20030059831A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,735 US6972185B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acids encoding PRO844 polypeptides |
US09/989,862 US20030130182A1 (en) | 1997-11-05 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,727 US20020072497A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,722 US20020072067A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,721 US20020142961A1 (en) | 1997-06-16 | 2001-11-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,726 US7018811B2 (en) | 1997-06-16 | 2001-11-19 | Nucleic acids encoding PRO189 polypeptides |
US09/989,293 US7034136B2 (en) | 1997-06-16 | 2001-11-20 | Nucleic acids encoding PRO1159 polypeptides |
US09/989,730 US7157247B2 (en) | 1997-06-16 | 2001-11-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,731 US20020103125A1 (en) | 1997-06-16 | 2001-11-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US09/989,728 US7029873B2 (en) | 1997-06-16 | 2001-11-20 | Nucleic acids to PRO1387 polypeptides |
US09/989,725 US20030139329A1 (en) | 1997-06-16 | 2001-11-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/001,054 US20020192209A1 (en) | 1997-09-17 | 2001-11-30 | Methods and compositions for inhibiting neoplastic cell growth |
US10/066,269 US20030040014A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/066,494 US20030032063A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/066,203 US20030180796A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/066,500 US20020177165A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding |
US10/066,211 US20030044844A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/066,198 US20030170721A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/066,273 US7317092B2 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/066,193 US20030044902A1 (en) | 1997-08-26 | 2002-02-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,046 US20030194791A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,047 US20030077778A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,051 US20030092147A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,041 US20030077776A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,042 US20030096386A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,044 US20030190717A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,045 US20030073210A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,059 US20030190721A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,040 US20030082759A1 (en) | 1997-03-31 | 2002-04-11 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,058 US20030190720A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,057 US20030190719A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,049 US20030022239A1 (en) | 1997-06-18 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,061 US20030082761A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,060 US20030190722A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,043 US7220831B2 (en) | 1997-03-31 | 2002-04-12 | PRO235 polypeptides |
US10/121,052 US20030199052A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,056 US20030082760A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,055 US20030190718A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,048 US20030199051A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,050 US20030054516A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,053 US20030199053A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,063 US20030199055A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,054 US20030199054A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/121,062 US20030077779A1 (en) | 1997-03-31 | 2002-04-12 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,155 US20030068794A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,235 US20030082762A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,215 US7291329B2 (en) | 1997-03-31 | 2002-04-15 | Antibodies against PRO4406 |
US10/123,322 US20030199059A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,213 US20030199057A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,214 US7343721B2 (en) | 1997-03-31 | 2002-04-15 | PRO4406 polypeptide |
US10/123,157 US20030190725A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,261 US20030068796A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,108 US7635478B2 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,154 US20030190724A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,262 US20030049816A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,213 US7193048B2 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,109 US20030190723A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,236 US20030068795A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,212 US7276577B2 (en) | 1997-03-31 | 2002-04-15 | PRO1866 polypeptides |
US10/123,292 US20030073211A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,156 US20030194792A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,291 US20030199058A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,771 US20030199060A1 (en) | 1997-03-31 | 2002-04-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,911 US7408032B2 (en) | 1997-03-31 | 2002-04-16 | PRO1188 polypeptides |
US10/123,912 US20030100087A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,906 US20030190726A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,903 US20030073212A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,904 US20030022328A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,910 US7329404B2 (en) | 1997-03-31 | 2002-04-16 | Antibodies against PRO1310 |
US10/123,902 US20030077781A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,907 US7084258B2 (en) | 1997-03-31 | 2002-04-16 | Antibodies against the PRO862 polypeptides |
US10/123,909 US7193049B2 (en) | 1997-03-31 | 2002-04-16 | PRO862 polypeptides |
US10/123,905 US7285625B2 (en) | 1997-06-18 | 2002-04-16 | PRO536 polypeptides |
US10/123,905 US20030087344A1 (en) | 1997-06-18 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/123,908 US7335728B2 (en) | 1997-03-31 | 2002-04-16 | PRO1310 polypeptides |
US10/123,913 US20030203462A1 (en) | 1997-03-31 | 2002-04-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,823 US20030199062A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,795 US7304131B2 (en) | 1997-03-31 | 2002-04-17 | PRO1483 polypeptides |
US10/124,814 US7105335B2 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,819 US7285626B2 (en) | 1997-03-31 | 2002-04-17 | PRO1076 polypeptides |
US10/124,822 US7109305B2 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,820 US20030190729A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,821 US20030199023A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,704 US7357926B2 (en) | 1997-03-31 | 2002-04-17 | Antibodies against PRO1879 and the use thereof |
US10/124,824 US20030077659A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,818 US20030082763A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,805 US20030194794A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,817 US20030077786A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/124,813 US7312307B2 (en) | 1997-03-31 | 2002-04-17 | PRO1056 polypeptides |
US10/124,816 US20030190728A1 (en) | 1997-03-31 | 2002-04-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,931 US20030199063A1 (en) | 1997-03-31 | 2002-04-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,924 US7342097B2 (en) | 1997-03-31 | 2002-04-19 | PRO1309 polypeptides |
US10/125,932 US7317079B2 (en) | 1997-03-31 | 2002-04-19 | PRO812 polypeptides |
US10/125,927 US20030190731A1 (en) | 1997-03-31 | 2002-04-19 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/125,922 US7309762B2 (en) | 1997-03-31 | 2002-04-19 | PRO1360 polypeptides |
US10/127,831 US20030082689A1 (en) | 1997-03-31 | 2002-04-22 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/128,689 US20030087365A1 (en) | 1997-03-31 | 2002-04-23 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/131,825 US7282566B2 (en) | 1997-03-31 | 2002-04-24 | PRO1779 polypeptide |
US10/131,817 US7291701B2 (en) | 1997-03-31 | 2002-04-24 | PRO1777 polypeptides |
US10/131,823 US7304132B2 (en) | 1997-03-31 | 2002-04-24 | PRO1693 polypeptides |
US10/137,865 US20030032155A1 (en) | 1997-03-31 | 2002-05-03 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/137,867 US20030207349A1 (en) | 1997-03-31 | 2002-05-03 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/137,868 US20030082764A1 (en) | 1997-03-31 | 2002-05-03 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,470 US20030022331A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/139,963 US7288625B2 (en) | 1997-03-31 | 2002-05-06 | PRO4395 polypeptides |
US10/139,980 US7247710B2 (en) | 1997-03-31 | 2002-05-06 | PRO4395 antibodies |
US10/140,020 US20030207415A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,023 US20030207416A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,024 US20040058424A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,474 US20030032156A1 (en) | 1997-03-31 | 2002-05-06 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,809 US20030207418A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,921 US7317080B2 (en) | 1997-03-31 | 2002-05-07 | PRO4303 polypeptides |
US10/140,808 US7425621B2 (en) | 1997-03-31 | 2002-05-07 | Antibodies against the PRO4401 polypeptide |
US10/140,865 US20030207420A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,864 US20030207419A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,805 US20030207417A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,860 US7307151B2 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,928 US20030068798A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/140,925 US20030073215A1 (en) | 1997-03-31 | 2002-05-07 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/141,754 US7361732B2 (en) | 1997-03-31 | 2002-05-08 | PRO4400 polypeptides |
US10/141,755 US7297764B2 (en) | 1997-03-31 | 2002-05-08 | PRO4318 polypeptides |
US10/141,756 US7488586B2 (en) | 1997-03-31 | 2002-05-08 | PRO4409 polypeptides |
US10/141,701 US20030207421A1 (en) | 1997-03-31 | 2002-05-08 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/141,760 US7342104B2 (en) | 1997-03-31 | 2002-05-08 | Antibodies against the PRO4320 polypeptide |
US10/142,425 US20030207424A1 (en) | 1997-03-31 | 2002-05-09 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/143,114 US20030036180A1 (en) | 1997-03-31 | 2002-05-09 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/142,430 US7309766B2 (en) | 1997-03-31 | 2002-05-09 | PRO5774 polypeptides |
US10/143,113 US7329730B2 (en) | 1997-03-31 | 2002-05-09 | PRO4348 polypeptides |
US10/142,417 US7304133B2 (en) | 1997-03-31 | 2002-05-09 | PRO4389 polypeptides |
US10/142,419 US7153941B2 (en) | 1997-03-31 | 2002-05-10 | Antibodies that bind PRO4994 polypeptides |
US10/143,032 US7408033B2 (en) | 1997-03-31 | 2002-05-10 | PRO5995 polypeptides |
US10/142,431 US7285629B2 (en) | 1997-03-31 | 2002-05-10 | Pro5005 polypeptides |
US10/142,423 US20030049817A1 (en) | 1997-03-31 | 2002-05-10 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/146,792 US20030207428A1 (en) | 1997-03-31 | 2002-05-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/146,730 US20030207427A1 (en) | 1997-03-31 | 2002-05-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,528 US20030219885A1 (en) | 1997-03-31 | 2002-05-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,519 US20030077791A1 (en) | 1997-03-31 | 2002-05-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,536 US20040077064A1 (en) | 1997-03-31 | 2002-05-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/147,492 US20030082765A1 (en) | 1997-03-31 | 2002-05-17 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/152,395 US7189534B2 (en) | 1997-03-31 | 2002-05-21 | PRO4320 polynucleotide |
US10/153,934 US20030129695A1 (en) | 1997-03-31 | 2002-05-22 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/156,843 US20030207805A1 (en) | 1997-06-18 | 2002-05-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/157,786 US20030208055A1 (en) | 1997-03-31 | 2002-05-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/157,782 US20030077792A1 (en) | 1997-03-31 | 2002-05-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/158,782 US20030082766A1 (en) | 1997-03-31 | 2002-05-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/160,498 US20030073216A1 (en) | 1997-03-31 | 2002-05-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/158,791 US20030207429A1 (en) | 1997-03-31 | 2002-05-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/176,913 US20030022298A1 (en) | 1997-09-15 | 2002-06-20 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/197,942 US20030175882A1 (en) | 1998-09-10 | 2002-07-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/226,739 US7390879B2 (en) | 1999-06-15 | 2002-08-23 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/242,652 US7238790B2 (en) | 1999-01-12 | 2002-09-11 | PRO1313 polypeptides |
US10/242,095 US7235642B1 (en) | 1999-01-12 | 2002-09-11 | Anti-PRO 1313 antibodies |
US10/245,852 US20030119134A1 (en) | 1999-01-12 | 2002-09-16 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US11/100,159 US7425613B2 (en) | 1997-11-05 | 2005-04-05 | PRO1375 polypeptides |
JP2005264293A JP2006068016A (en) | 1999-12-01 | 2005-08-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US11/240,891 US20060246540A1 (en) | 1997-08-26 | 2005-09-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US11/341,175 US7468427B2 (en) | 1997-03-31 | 2006-01-27 | Antibodies to PRO1275 polypeptide |
JP2007326424A JP2008167749A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptide and nucleic acid encoding the same |
JP2007326613A JP2008161190A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptide and nucleic acid encoding the same |
JP2007325484A JP2008148699A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2007326609A JP2008148701A (en) | 1999-12-01 | 2007-12-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
Applications Claiming Priority (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1999/028313 WO2000032221A2 (en) | 1998-12-01 | 1999-11-30 | Promotion or inhibition of angiogenesis and cardiovascularization |
USPCT/US99/28409 | 1999-11-30 | ||
USPCT/US99/28313 | 1999-11-30 | ||
PCT/US1999/028409 WO2000032778A2 (en) | 1998-12-01 | 1999-11-30 | Methods and compositions for inhibiting neoplastic cell growth |
USPCT/US00/00219 | 2000-01-05 | ||
PCT/US2000/000219 WO2000053753A2 (en) | 1999-03-08 | 2000-01-05 | Promotion or inhibition of angiogenesis and cardiovascularization |
USPCT/US00/05004 | 2000-02-24 | ||
PCT/US2000/005004 WO2000053757A2 (en) | 1999-03-08 | 2000-02-24 | Promotion or inhibition of angiogenesis and cardiovascularization |
PCT/US2000/006884 WO2001005972A1 (en) | 1999-07-20 | 2000-03-15 | Compositions and methods for the treatment of immune related diseases |
USPCT/US00/06884 | 2000-03-15 | ||
USPCT/US00/08439 | 2000-03-30 | ||
PCT/US2000/008439 WO2000073454A1 (en) | 1999-06-02 | 2000-03-30 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
PCT/US2000/013705 WO2000073445A2 (en) | 1999-06-02 | 2000-05-17 | Interleukin-1-receptor associated kinase-3 (irak3) |
USPCT/US00/13705 | 2000-05-17 | ||
USPCT/US00/14941 | 2000-05-30 | ||
PCT/US2000/014941 WO2000073348A2 (en) | 1999-06-02 | 2000-05-30 | Methods and compositions for inhibiting neoplastic cell growth |
USPCT/US00/20710 | 2000-07-28 | ||
PCT/US2000/020710 WO2001009327A2 (en) | 1999-07-28 | 2000-07-28 | Method of preventing the injury or death of retinal cells and treating ocular diseases |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/028313 Continuation-In-Part WO2000032221A2 (en) | 1994-09-08 | 1999-11-30 | Promotion or inhibition of angiogenesis and cardiovascularization |
PCT/US2000/015264 Continuation-In-Part WO2000073452A2 (en) | 1994-09-08 | 2000-06-02 | Compositions and methods for the treatment of immune related diseases |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/023522 Continuation-In-Part WO2001016319A2 (en) | 1996-11-06 | 2000-08-23 | Compositions and methods for the treatment of immune related diseases |
PCT/US2001/027099 Continuation-In-Part WO2002024888A2 (en) | 1997-09-15 | 2001-08-29 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US10/197,942 Continuation US20030175882A1 (en) | 1998-03-27 | 2002-07-18 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
Publications (2)
Publication Number | Publication Date |
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WO2001040464A1 WO2001040464A1 (en) | 2001-06-07 |
WO2001040464A8 true WO2001040464A8 (en) | 2001-06-28 |
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PCT/US2000/022031 WO2001040464A1 (en) | 1996-11-06 | 2000-08-11 | Interleukin-1-receptor associated kinase-3 (irak3) and its use in promotion or inhibition of angiogenesis and cardiovascularization |
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Families Citing this family (8)
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US6406867B1 (en) | 1996-08-16 | 2002-06-18 | Human Genome Sciences, Inc. | Antibody to human endokine alpha and methods of use |
EP1161451A4 (en) * | 1999-02-26 | 2006-05-17 | Human Genome Sciences Inc | Human endokine alpha and methods of use |
JP2005516586A (en) * | 2001-07-20 | 2005-06-09 | ボード オブ トラスティーズ オブ ザ ユニヴァースティ オブ イリノイ | Reagents and methods for identifying gene targets for the treatment of cancer |
AU2002366433A1 (en) * | 2001-08-16 | 2003-09-09 | Human Genome Sciences, Inc. | Methods and compositions for treating metabolic bone diseases relating to human endokine alpha |
WO2015187835A2 (en) | 2014-06-06 | 2015-12-10 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof |
EP3304079B1 (en) | 2015-06-03 | 2020-06-03 | Bristol-Myers Squibb Company | Anti-gitr antibodies for cancer diagnostics |
ES2926969T3 (en) | 2015-11-19 | 2022-10-31 | Bristol Myers Squibb Co | Glucocorticoid-induced tumor necrosis factor receptor (gitr) antibodies and uses thereof |
CN110869392A (en) | 2017-05-16 | 2020-03-06 | 百时美施贵宝公司 | Treatment of cancer with anti-GITR agonistic antibodies |
Family Cites Families (6)
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US4900673A (en) * | 1988-03-28 | 1990-02-13 | President And Fellows Of Harvard College | Mutant human angiogenin (angiogenesis factor with superior angiogenin activity) genes therefor and methods of expression |
WO1995029242A1 (en) * | 1994-04-26 | 1995-11-02 | The Children's Medical Center Corporation | Angiostatin and method of use for inhibition of angiogenesis |
NZ334035A (en) * | 1996-08-16 | 2000-09-29 | Human Genome Sciences Inc | Use of endokine alpha antagonists to diagnose and treat TNF-related disorders |
CA2308365A1 (en) * | 1997-11-18 | 1999-05-27 | Genentech, Inc. | Dna19355 polypeptide, a tumor necrosis factor homolog |
IL137409A0 (en) * | 1998-02-09 | 2001-07-24 | Genentech Inc | Novel tumor necrosis factor receptor homolog and nucleic acids encoding the same |
EP1161451A4 (en) * | 1999-02-26 | 2006-05-17 | Human Genome Sciences Inc | Human endokine alpha and methods of use |
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