WO2001028590A3 - PHARMACEUTICAL COMPOSITIONS CONTAINING N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE METHYL ESTER - Google Patents

PHARMACEUTICAL COMPOSITIONS CONTAINING N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE METHYL ESTER Download PDF

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Publication number
WO2001028590A3
WO2001028590A3 PCT/US2000/028731 US0028731W WO0128590A3 WO 2001028590 A3 WO2001028590 A3 WO 2001028590A3 US 0028731 W US0028731 W US 0028731W WO 0128590 A3 WO0128590 A3 WO 0128590A3
Authority
WO
WIPO (PCT)
Prior art keywords
aspartyl
dimethylbutyl
pharmaceutical compositions
methyl ester
compositions containing
Prior art date
Application number
PCT/US2000/028731
Other languages
French (fr)
Other versions
WO2001028590A2 (en
Inventor
Subbarao V Ponakala
Original Assignee
Nutrasweet Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrasweet Co filed Critical Nutrasweet Co
Priority to AU10934/01A priority Critical patent/AU1093401A/en
Publication of WO2001028590A2 publication Critical patent/WO2001028590A2/en
Publication of WO2001028590A3 publication Critical patent/WO2001028590A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Seasonings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Pharmaceutical products and related compositions comprising neotame are disclosed. The pharmaceutical compositions have been found to have improved taste or aroma characteristics.
PCT/US2000/028731 1999-10-19 2000-10-18 PHARMACEUTICAL COMPOSITIONS CONTAINING N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE METHYL ESTER WO2001028590A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU10934/01A AU1093401A (en) 1999-10-19 2000-10-18 Pharmaceutical compositions containing n-(n-(3,3-dimethylbutyl)-1-alpha-aspartyl)-l-phenylalanine methyl ester

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16030599P 1999-10-19 1999-10-19
US60/160,305 1999-10-19

Publications (2)

Publication Number Publication Date
WO2001028590A2 WO2001028590A2 (en) 2001-04-26
WO2001028590A3 true WO2001028590A3 (en) 2008-01-03

Family

ID=22576354

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/028731 WO2001028590A2 (en) 1999-10-19 2000-10-18 PHARMACEUTICAL COMPOSITIONS CONTAINING N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE METHYL ESTER

Country Status (2)

Country Link
AU (1) AU1093401A (en)
WO (1) WO2001028590A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859603B1 (en) * 2003-09-11 2005-12-30 Christian Fenioux USE OF NEOHESPERIDINE DIHYDROCHALCONE IN ORAL COMPOSITIONS COMPRISING VITAMINS AND / OR MINERALS
JP5852783B2 (en) * 2011-02-25 2016-02-03 小川香料株式会社 Taste improver for high-intensity sweeteners
GB2551986A (en) 2016-07-01 2018-01-10 Gw Res Ltd Parenteral formulations
GB2551987A (en) 2016-07-01 2018-01-10 Gw Res Ltd Oral cannabinoid formulations
GB2559774B (en) 2017-02-17 2021-09-29 Gw Res Ltd Oral cannabinoid formulations
GB2569961B (en) 2018-01-03 2021-12-22 Gw Res Ltd Pharmaceutical

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0866073A1 (en) * 1997-03-18 1998-09-23 Ajinomoto Co., Ltd. Novel dipeptide derivatives and sweetening agents
WO1999012957A1 (en) * 1997-09-11 1999-03-18 The Nutrasweet Company BASIC SALTS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHE NYLALANINE 1-METHYL ESTER
WO1999030576A1 (en) * 1997-12-17 1999-06-24 The Nutrasweet Company Beverage compositions comprising sweetener with extremely high potency
JPH11279081A (en) * 1998-03-27 1999-10-12 Ajinomoto Co Inc Composition containing bitter material
WO1999057998A1 (en) * 1998-05-08 1999-11-18 Ajinomoto Co., Inc. Novel sweetener compositions
WO1999062354A1 (en) * 1998-06-05 1999-12-09 Wm. Wrigley Jr. Company Method of controlling release of n-substituted derivatives of aspartame in chewing gum and gum produced thereby
WO2000036933A1 (en) * 1998-12-18 2000-06-29 The Nutrasweet Company USE OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER AS A FLAVOR MODIFIER
WO2000057726A1 (en) * 1999-03-29 2000-10-05 The Nutrasweet Company NUTRACEUTICALS HAVING N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0866073A1 (en) * 1997-03-18 1998-09-23 Ajinomoto Co., Ltd. Novel dipeptide derivatives and sweetening agents
WO1999012957A1 (en) * 1997-09-11 1999-03-18 The Nutrasweet Company BASIC SALTS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHE NYLALANINE 1-METHYL ESTER
WO1999030576A1 (en) * 1997-12-17 1999-06-24 The Nutrasweet Company Beverage compositions comprising sweetener with extremely high potency
JPH11279081A (en) * 1998-03-27 1999-10-12 Ajinomoto Co Inc Composition containing bitter material
WO1999057998A1 (en) * 1998-05-08 1999-11-18 Ajinomoto Co., Inc. Novel sweetener compositions
JPH11318381A (en) * 1998-05-08 1999-11-24 Ajinomoto Co Inc New sweetener composition
WO1999062354A1 (en) * 1998-06-05 1999-12-09 Wm. Wrigley Jr. Company Method of controlling release of n-substituted derivatives of aspartame in chewing gum and gum produced thereby
WO2000036933A1 (en) * 1998-12-18 2000-06-29 The Nutrasweet Company USE OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER AS A FLAVOR MODIFIER
WO2000057726A1 (en) * 1999-03-29 2000-10-05 The Nutrasweet Company NUTRACEUTICALS HAVING N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200006, Derwent World Patents Index; AN 2000-053011 *
PATENT ABSTRACTS OF JAPAN vol. 2000, no. 1 31 January 2000 (2000-01-31) *

Also Published As

Publication number Publication date
WO2001028590A2 (en) 2001-04-26
AU1093401A (en) 2001-04-30

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