WO2001027594A3 - Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen - Google Patents

Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen Download PDF

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Publication number
WO2001027594A3
WO2001027594A3 PCT/DE2000/003577 DE0003577W WO0127594A3 WO 2001027594 A3 WO2001027594 A3 WO 2001027594A3 DE 0003577 W DE0003577 W DE 0003577W WO 0127594 A3 WO0127594 A3 WO 0127594A3
Authority
WO
WIPO (PCT)
Prior art keywords
measuring
dispersive infrared
ratios
respiratory gases
infrared spectrometers
Prior art date
Application number
PCT/DE2000/003577
Other languages
English (en)
French (fr)
Other versions
WO2001027594A2 (de
Inventor
Heinz Fischer
Original Assignee
Heinz Fischer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19949212A external-priority patent/DE19949212A1/de
Application filed by Heinz Fischer filed Critical Heinz Fischer
Publication of WO2001027594A2 publication Critical patent/WO2001027594A2/de
Publication of WO2001027594A3 publication Critical patent/WO2001027594A3/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3504—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/43—Composition of exhalation
    • A61M2230/432—Composition of exhalation partial CO2 pressure (P-CO2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/61—Non-dispersive gas analysers

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  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Der Erfindung liegt die Aufgabe zugrunde, ein einfaches und sicheres Verfahren zur Eliminierung des Einflusses der CO2-Konzentration auf die Messsignale nichtdispersiver Infrarotspektrometer zur Bestimmung von 13CO2/12CO2-Verhältnissen in Atemgasen bereitzustellen, welches gewährleistet, dass bei Kalibrierung und Messung weitgehend gleiche physikalische Bedingungen herrschen. Erfindungsgemäss werden die beiden Kammern der Messküvette des nichtdispersiven Infrarotspektrometers zunächst mit einem CO2-freien Gas gefüllt, der Nullpunkt eingestellt und dann eine Küvette bekannten CO2-Gehalts und 13CO2/12CO2-Verhältnisses in den Strahlengang gerückt. Das sich dann einstellende Messsignal für 12CO2 wird in der Phase der Messung reproduziert, indem das Messgas dem CO2-freien Gas in der einen der beiden Kammern der Messküvette in der erforderlichen Menge zudosiert wird. Das wichtigste Anwendungsgebiet des erfindungsgemässen Verfahrens ist die Anwendung von 13C-Atemtests in der medizinischen Forschung und Diagnostik.
PCT/DE2000/003577 1999-10-13 2000-10-11 Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen WO2001027594A2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE29923125U DE29923125U1 (de) 1999-10-13 1999-10-13 Vorrichtung zur Kalibrierung nichtdispersiver Infrarotspektrometer
DE19949212A DE19949212A1 (de) 1999-10-13 1999-10-13 Verfahren zur Kalibrierung nichtdispersiver Infrarotspektrometer für die Messung von 13C/12C-Verhältnissen in Atemgasen
DE29923125.9 1999-10-13
DE19949212.3 1999-10-13

Publications (2)

Publication Number Publication Date
WO2001027594A2 WO2001027594A2 (de) 2001-04-19
WO2001027594A3 true WO2001027594A3 (de) 2001-12-27

Family

ID=26055257

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/003577 WO2001027594A2 (de) 1999-10-13 2000-10-11 Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen

Country Status (2)

Country Link
DE (1) DE29923125U1 (de)
WO (1) WO2001027594A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004031643A1 (de) * 2004-06-30 2006-02-02 Abb Patent Gmbh Nichtdispersiver Infrarot-Gasanalysator

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19714903A1 (de) * 1997-04-10 1998-10-29 Hartmann & Braun Gmbh & Co Kg Verfahren zur Kalibrierung von NDIR-Spektrometern
DE19731889A1 (de) * 1997-07-24 1999-01-28 Fischer Analysen Instr Gmbh Verfahren zur Kalibrierung von Isotopenanalysatoren
DE19735599A1 (de) * 1997-08-15 1999-03-04 Peter Prof Dr Hering Verfahren und Vorrichtung zur gleichzeitigen Messung von Konzentrationen verschiedener Gaskomponenten insbesondere zur Messung von Isotopenverhältnissen in Gasen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19714903A1 (de) * 1997-04-10 1998-10-29 Hartmann & Braun Gmbh & Co Kg Verfahren zur Kalibrierung von NDIR-Spektrometern
DE19731889A1 (de) * 1997-07-24 1999-01-28 Fischer Analysen Instr Gmbh Verfahren zur Kalibrierung von Isotopenanalysatoren
DE19735599A1 (de) * 1997-08-15 1999-03-04 Peter Prof Dr Hering Verfahren und Vorrichtung zur gleichzeitigen Messung von Konzentrationen verschiedener Gaskomponenten insbesondere zur Messung von Isotopenverhältnissen in Gasen

Also Published As

Publication number Publication date
WO2001027594A2 (de) 2001-04-19
DE29923125U1 (de) 2000-06-29

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