WO2001027594A3 - Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen - Google Patents
Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen Download PDFInfo
- Publication number
- WO2001027594A3 WO2001027594A3 PCT/DE2000/003577 DE0003577W WO0127594A3 WO 2001027594 A3 WO2001027594 A3 WO 2001027594A3 DE 0003577 W DE0003577 W DE 0003577W WO 0127594 A3 WO0127594 A3 WO 0127594A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- measuring
- dispersive infrared
- ratios
- respiratory gases
- infrared spectrometers
- Prior art date
Links
- 239000007789 gas Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 230000000241 respiratory effect Effects 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/3504—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
- A61B5/0836—Measuring rate of CO2 production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
- A61M2230/43—Composition of exhalation
- A61M2230/432—Composition of exhalation partial CO2 pressure (P-CO2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
- G01N21/61—Non-dispersive gas analysers
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Der Erfindung liegt die Aufgabe zugrunde, ein einfaches und sicheres Verfahren zur Eliminierung des Einflusses der CO2-Konzentration auf die Messsignale nichtdispersiver Infrarotspektrometer zur Bestimmung von 13CO2/12CO2-Verhältnissen in Atemgasen bereitzustellen, welches gewährleistet, dass bei Kalibrierung und Messung weitgehend gleiche physikalische Bedingungen herrschen. Erfindungsgemäss werden die beiden Kammern der Messküvette des nichtdispersiven Infrarotspektrometers zunächst mit einem CO2-freien Gas gefüllt, der Nullpunkt eingestellt und dann eine Küvette bekannten CO2-Gehalts und 13CO2/12CO2-Verhältnisses in den Strahlengang gerückt. Das sich dann einstellende Messsignal für 12CO2 wird in der Phase der Messung reproduziert, indem das Messgas dem CO2-freien Gas in der einen der beiden Kammern der Messküvette in der erforderlichen Menge zudosiert wird. Das wichtigste Anwendungsgebiet des erfindungsgemässen Verfahrens ist die Anwendung von 13C-Atemtests in der medizinischen Forschung und Diagnostik.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE29923125U DE29923125U1 (de) | 1999-10-13 | 1999-10-13 | Vorrichtung zur Kalibrierung nichtdispersiver Infrarotspektrometer |
DE19949212A DE19949212A1 (de) | 1999-10-13 | 1999-10-13 | Verfahren zur Kalibrierung nichtdispersiver Infrarotspektrometer für die Messung von 13C/12C-Verhältnissen in Atemgasen |
DE29923125.9 | 1999-10-13 | ||
DE19949212.3 | 1999-10-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001027594A2 WO2001027594A2 (de) | 2001-04-19 |
WO2001027594A3 true WO2001027594A3 (de) | 2001-12-27 |
Family
ID=26055257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2000/003577 WO2001027594A2 (de) | 1999-10-13 | 2000-10-11 | Verfahren zur kalibrierung nichtdispersiver infrarotspektrometer für die messung von 13c/12c-verhältnissen in atemgasen |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE29923125U1 (de) |
WO (1) | WO2001027594A2 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004031643A1 (de) * | 2004-06-30 | 2006-02-02 | Abb Patent Gmbh | Nichtdispersiver Infrarot-Gasanalysator |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19714903A1 (de) * | 1997-04-10 | 1998-10-29 | Hartmann & Braun Gmbh & Co Kg | Verfahren zur Kalibrierung von NDIR-Spektrometern |
DE19731889A1 (de) * | 1997-07-24 | 1999-01-28 | Fischer Analysen Instr Gmbh | Verfahren zur Kalibrierung von Isotopenanalysatoren |
DE19735599A1 (de) * | 1997-08-15 | 1999-03-04 | Peter Prof Dr Hering | Verfahren und Vorrichtung zur gleichzeitigen Messung von Konzentrationen verschiedener Gaskomponenten insbesondere zur Messung von Isotopenverhältnissen in Gasen |
-
1999
- 1999-10-13 DE DE29923125U patent/DE29923125U1/de not_active Expired - Lifetime
-
2000
- 2000-10-11 WO PCT/DE2000/003577 patent/WO2001027594A2/de active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19714903A1 (de) * | 1997-04-10 | 1998-10-29 | Hartmann & Braun Gmbh & Co Kg | Verfahren zur Kalibrierung von NDIR-Spektrometern |
DE19731889A1 (de) * | 1997-07-24 | 1999-01-28 | Fischer Analysen Instr Gmbh | Verfahren zur Kalibrierung von Isotopenanalysatoren |
DE19735599A1 (de) * | 1997-08-15 | 1999-03-04 | Peter Prof Dr Hering | Verfahren und Vorrichtung zur gleichzeitigen Messung von Konzentrationen verschiedener Gaskomponenten insbesondere zur Messung von Isotopenverhältnissen in Gasen |
Also Published As
Publication number | Publication date |
---|---|
WO2001027594A2 (de) | 2001-04-19 |
DE29923125U1 (de) | 2000-06-29 |
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