WO2001022881A8 - System for transdermally obtaining body fluids - Google Patents

System for transdermally obtaining body fluids

Info

Publication number
WO2001022881A8
WO2001022881A8 PCT/EP2000/009175 EP0009175W WO0122881A8 WO 2001022881 A8 WO2001022881 A8 WO 2001022881A8 EP 0009175 W EP0009175 W EP 0009175W WO 0122881 A8 WO0122881 A8 WO 0122881A8
Authority
WO
WIPO (PCT)
Prior art keywords
transdermally
particle
body fluids
obtaining body
inventive system
Prior art date
Application number
PCT/EP2000/009175
Other languages
German (de)
French (fr)
Other versions
WO2001022881A1 (en
Inventor
Matthias Essenpreis
Dirk Boecker
Original Assignee
Roche Diagnostics Gmbh
Matthias Essenpreis
Dirk Boecker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Matthias Essenpreis, Dirk Boecker filed Critical Roche Diagnostics Gmbh
Priority to EP00964207A priority Critical patent/EP1220641A1/en
Publication of WO2001022881A1 publication Critical patent/WO2001022881A1/en
Publication of WO2001022881A8 publication Critical patent/WO2001022881A8/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B2010/008Interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention relates to a system for transdermally obtaining body fluids to determine at least one analyte. The inventive system comprises a device for transdermally applying at least one particle. Said device is provided with an acceleration device that accelerates the at least one particle to a speed that allows the particle to penetrate a skin area right to the epidermis or dermis and with a release mechanism for releasing the acceleration device and a reservoir for the at least one particle. The particles used in the inventive system are preferably of the kind to be absorbed by the body.
PCT/EP2000/009175 1999-09-25 2000-09-20 System for transdermally obtaining body fluids WO2001022881A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP00964207A EP1220641A1 (en) 1999-09-25 2000-09-20 System for transdermally obtaining body fluids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19946059.0 1999-09-25
DE1999146059 DE19946059A1 (en) 1999-09-25 1999-09-25 System for the transdermal production of body fluid

Publications (2)

Publication Number Publication Date
WO2001022881A1 WO2001022881A1 (en) 2001-04-05
WO2001022881A8 true WO2001022881A8 (en) 2002-05-30

Family

ID=7923327

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/009175 WO2001022881A1 (en) 1999-09-25 2000-09-20 System for transdermally obtaining body fluids

Country Status (3)

Country Link
EP (1) EP1220641A1 (en)
DE (1) DE19946059A1 (en)
WO (1) WO2001022881A1 (en)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US35803A (en) * 1862-07-01 Improvement in sash-fasteners
CH500707A (en) * 1968-07-26 1970-12-31 Micromedic Systems Inc Device for performing percutaneous and digital blood sampling
US4326524A (en) * 1980-09-30 1982-04-27 Minnesota Mining And Manufacturing Company Solid dose ballistic projectile
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US5243516A (en) * 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
US5204253A (en) * 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5421816A (en) * 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5458140A (en) * 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
DE69738420T2 (en) * 1996-05-17 2008-05-21 Roche Diagnostics Operations, Inc., Indianapolis BODY FLUID COLLECTION DEVICE
US5951492A (en) * 1996-05-17 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for sampling and analyzing body fluid
JP2828064B2 (en) * 1996-09-20 1998-11-25 日本電気株式会社 Suction leachate collection method and device
US6030399A (en) * 1997-06-04 2000-02-29 Spectrx, Inc. Fluid jet blood sampling device and methods
US6074360A (en) * 1997-07-21 2000-06-13 Boehringer Mannheim Gmbh Electromagnetic transdermal injection device and methods related thereto

Also Published As

Publication number Publication date
DE19946059A1 (en) 2001-03-29
WO2001022881A1 (en) 2001-04-05
EP1220641A1 (en) 2002-07-10

Similar Documents

Publication Publication Date Title
BRPI0416822A (en) Transdermal Ultrasound Vaccine Release Method and System
BRPI0517501A (en) medical device suitable for use in the administration of an active ingredient to or through the skin
IE800059L (en) Polymeric diffusion matrix
AU2088301A (en) Device for enhancing transdermal flux of sampled agents
WO2007070719A3 (en) Tissue penetration device
PT1037686E (en) APPARATUS FOR POTENTIATING THE FLOW OF TRANSDERMMIC AGENT
WO2005018705A3 (en) Patch-like infusion device
ES2108006T3 (en) PREPARATION OF THE BLOOD MICRO SAMPLE TAKING AREA.
GB9720242D0 (en) Device for exfoliating the stratum corneum of the epidermis and revitalising the skin
WO2004060447A3 (en) Transdermal delivery using encapsulated agent activated by ultrasound and/or heat
EP1281367A3 (en) Laser adapted to assist topical anesthetic permeation
BRPI0417757A (en) frequency-assisted transdermal agent release method and system
AU4923500A (en) Device and method for increasing the transdermal permeation of medicaments
WO2001092477A3 (en) Three-dimensional skin model
BRPI0415986A (en) method and apparatus for reducing the incidence of tobacco use
MY103355A (en) Active substance-containing plaster of the controlled administration of active substances to the skin, the use thereof and a process for the controlled administration of active substances to the skin
WO2007121107A3 (en) Device and method for applying a biocompatible substance to a female stimulation device
WO2005067499A3 (en) Method and device for topical delivery of therapeutic agents to the skin
CA2338859A1 (en) Estradiol-containing patch for transdermal administration of hormones
BR9008012A (en) METHOD AND DEVICE FOR SKIN DRUG RELEASE
NZ509215A (en) Transdermal plaster preparation containing at least one active ingredient which influences blood serum lipid levels
WO2001022881A8 (en) System for transdermally obtaining body fluids
ES2058627T3 (en) THERAPEUTIC SYSTEM FOR DELAYED ADMINISTRATION AND DIRECTED THROUGH THE SKIN OR THE MUCOUS OF ACTIVE SUBSTANCES.
AU4739089A (en) Superficial therapeutic system comprising an anti-neoplastic active substance, particularly 5-fluorouracil
HUP0003347A3 (en) Transdermal therapy system (tts) for releasing an active agent and method for applying said transdermal therapy system to the skin

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000964207

Country of ref document: EP

AK Designated states

Kind code of ref document: C1

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i
WWP Wipo information: published in national office

Ref document number: 2000964207

Country of ref document: EP

NENP Non-entry into the national phase in:

Ref country code: JP

WWW Wipo information: withdrawn in national office

Ref document number: 2000964207

Country of ref document: EP