WO2001018231A3 - VERFAHREN ZUR HERSTELLUNG VON (R)- ODER (S)-HYDROXY-η-BUTYROLACTON - Google Patents

VERFAHREN ZUR HERSTELLUNG VON (R)- ODER (S)-HYDROXY-η-BUTYROLACTON Download PDF

Info

Publication number
WO2001018231A3
WO2001018231A3 PCT/EP2000/008810 EP0008810W WO0118231A3 WO 2001018231 A3 WO2001018231 A3 WO 2001018231A3 EP 0008810 W EP0008810 W EP 0008810W WO 0118231 A3 WO0118231 A3 WO 0118231A3
Authority
WO
WIPO (PCT)
Prior art keywords
producing
butyrolactone
hydroxy
formulas
butyrolactones
Prior art date
Application number
PCT/EP2000/008810
Other languages
English (en)
French (fr)
Other versions
WO2001018231A2 (de
Inventor
Michael Petersen
Georges Kalbermatten
Original Assignee
Lonza Ag
Michael Petersen
Georges Kalbermatten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag, Michael Petersen, Georges Kalbermatten filed Critical Lonza Ag
Priority to AU74181/00A priority Critical patent/AU7418100A/en
Publication of WO2001018231A2 publication Critical patent/WO2001018231A2/de
Publication of WO2001018231A3 publication Critical patent/WO2001018231A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Beschrieben wird ein neues Verfahren zur Herstellung von (R)- und/oder (S)-2-Hydroxy-η-butyrolactonen der Formeln (I) und (II) und/oder von (S)- und/oder (R)-2-Acyloxy-η-butyrolactonen der allgemeinen Formeln (III) und (IV), worin ein racemisches 2-Acyloxy-η-butyrolacton der allgemeinen Formel (V) mittels Hydrolasen in die Verbindungen der Formeln (I) oder (II) umgesetzt wird, wobei die Verbindungen der Formeln (III) oder (IV) anfallen.
PCT/EP2000/008810 1999-09-08 2000-09-08 VERFAHREN ZUR HERSTELLUNG VON (R)- ODER (S)-HYDROXY-η-BUTYROLACTON WO2001018231A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU74181/00A AU7418100A (en) 1999-09-08 2000-09-08 Method for producing (r) or (s)-hydroxy-gamma-butyrolactone

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP99117685.0 1999-09-08
EP99117685 1999-09-08
US18536600P 2000-02-28 2000-02-28
US60/185,366 2000-02-28

Publications (2)

Publication Number Publication Date
WO2001018231A2 WO2001018231A2 (de) 2001-03-15
WO2001018231A3 true WO2001018231A3 (de) 2001-09-13

Family

ID=26153103

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/008810 WO2001018231A2 (de) 1999-09-08 2000-09-08 VERFAHREN ZUR HERSTELLUNG VON (R)- ODER (S)-HYDROXY-η-BUTYROLACTON

Country Status (2)

Country Link
AU (1) AU7418100A (de)
WO (1) WO2001018231A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1532146B1 (de) * 2002-08-22 2006-03-01 Neurosearch A/S Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivaten
WO2017190116A1 (en) 2016-04-29 2017-11-02 Wisconsin Alumni Research Foundation Synthetic ligands that modulate the activity of the rhlr quorum sensing receptor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0439779A2 (de) * 1990-02-02 1991-08-07 Chisso Corporation Verfahren zur Herstellung von optisch aktiven Hydroxylactonen
EP0467132A2 (de) * 1990-07-17 1992-01-22 Chisso Corporation 4-Substituierte-2-hydroxybutanoate und ein Verfahren zu ihrer Herstellung
GB2347674A (en) * 1999-03-09 2000-09-13 Chisso Corp Producing optically active alpha-hydroxylactones

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0439779A2 (de) * 1990-02-02 1991-08-07 Chisso Corporation Verfahren zur Herstellung von optisch aktiven Hydroxylactonen
EP0467132A2 (de) * 1990-07-17 1992-01-22 Chisso Corporation 4-Substituierte-2-hydroxybutanoate und ein Verfahren zu ihrer Herstellung
GB2347674A (en) * 1999-03-09 2000-09-13 Chisso Corp Producing optically active alpha-hydroxylactones

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
E. FRANCOTTE ET AL.: "Analytic and preparative resolution of .gamma.-and .delta.-lactones by chromatography on cellulose triacetate. Relationship between elution order and absolute configuration", HELVETICA CHIMICA ACTA., vol. 70, 1987, VERLAG HELVETICA CHIMICA ACTA. BASEL., CH, pages 1569 - 1582, XP002163690, ISSN: 0018-019X *
R.N. BEN ET AL.: "Synthesis of Optically Active alpha-Amino Esters via Dynamic Kinetic Resolution: A Mechanistic Study", JOURNAL OF ORGANIC CHEMISTRY, vol. 64, 1999, EASTON US, pages 7700 - 7706, XP002163691 *

Also Published As

Publication number Publication date
WO2001018231A2 (de) 2001-03-15
AU7418100A (en) 2001-04-10

Similar Documents

Publication Publication Date Title
HU9601857D0 (en) New benzyl-piperidine- or -tetrahydro-pyridine derivatives and processes for producing them
GR20010100398A (el) Μεθοδος παρασκευης της σιταλοπραμης.
CY1112711T1 (el) ΜΕΘΟΔΟΣ ΓΙΑ ΤΗΝ ΠΑΡΑΣΚΕΥΗ ΠΑΡΑΓΩΓΩΝ ΚΥΚΛΟΠΕΝΤΑ[g]ΚΙΝΑΖΟΛΙΝΗΣ
AU2003293585A1 (en) Intermediate cefdinir salts
WO2001057014A3 (en) Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one
IS6435A (is) Aðferð til framleiðslu á sítalóprami
WO2003011849A8 (en) Process for the production of beraprost and its salts
DE60235365D1 (de) Verfahren zur herstellung von 7-amino-syn-3,5-dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung
EA199900790A1 (ru) Способы получения пестицидных промежуточных соединений
BG105766A (en) New process for preparing pesticidal intermediates
AU6578400A (en) Novel method for preparing benzoperhydroisoindole compounds
WO2001018231A3 (de) VERFAHREN ZUR HERSTELLUNG VON (R)- ODER (S)-HYDROXY-η-BUTYROLACTON
WO2002046152A3 (de) Coniosetin und derivate davon, verfahren zur herstellung und verwendung derselben
BG104073A (en) Method for preparing alkyloxy furanone derivatives, compounds obtained by said method and use of said compounds
WO2002053537A8 (en) Process for preparing (±) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine
MXPA04003086A (es) Proceso para sintesis estereoselectiva de 2-hidroximetil-cromanos.
AU3219700A (en) Method for the preparation of a chiral-beta-amino ester
WO2004034983A3 (en) Preparation of triazospiro compounds
WO2002061094A3 (de) Mikrobiologisches verfahren zur herstellung von l-carnitin
BG108151A (en) Caloporoside derivatives, methods for the production thereof and their use
HU0201584D0 (de)
EP1698611A4 (de) Verfahren zur herstellung von phenylessigsäurederivaten
WO2000018777A3 (en) Method for synthesizing c-glycosides of ulosonic acids
TR200001161A2 (tr) 8-Siklopentil-6-etil-3-[ikame edilmiş]-5, 8-Dihidro-4H-1, 2, 3A, 7, 8-Pentaaza-As-Indasenlerin hazırlandığı işlem ve burada yararlı ara bağlar.
YU75703A (sh) Postupak za pripremanje tetrasupstituisanih derivata imidazola i njihove nove kristalne strukure

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP