WO2001007605A8 - Immunosuppression by cell surface expression of recombinant cd154 - Google Patents

Immunosuppression by cell surface expression of recombinant cd154

Info

Publication number
WO2001007605A8
WO2001007605A8 PCT/GB2000/002652 GB0002652W WO0107605A8 WO 2001007605 A8 WO2001007605 A8 WO 2001007605A8 GB 0002652 W GB0002652 W GB 0002652W WO 0107605 A8 WO0107605 A8 WO 0107605A8
Authority
WO
WIPO (PCT)
Prior art keywords
cell surface
immunosuppression
recombinant
surface expression
organs
Prior art date
Application number
PCT/GB2000/002652
Other languages
French (fr)
Other versions
WO2001007605A1 (en
Inventor
Andrew William Heath
Original Assignee
Univ Sheffield
Andrew William Heath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Sheffield, Andrew William Heath filed Critical Univ Sheffield
Priority to AU59967/00A priority Critical patent/AU5996700A/en
Priority to EP00946079A priority patent/EP1210420A1/en
Publication of WO2001007605A1 publication Critical patent/WO2001007605A1/en
Publication of WO2001007605A8 publication Critical patent/WO2001007605A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to cells and/or tissues and/or organs which do not naturally express the cell surface receptor CD40 ligand, CD154, for use in therapeutic and cosmetic tissue engineering and/or organ transplantation.
PCT/GB2000/002652 1999-07-23 2000-07-10 Immunosuppression by cell surface expression of recombinant cd154 WO2001007605A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU59967/00A AU5996700A (en) 1999-07-23 2000-07-10 Cd154 ligand, and recombinant cells expressing it
EP00946079A EP1210420A1 (en) 1999-07-23 2000-07-10 Cd154 ligand, and recombinant cells expressing it

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9917180.3A GB9917180D0 (en) 1999-07-23 1999-07-23 Cell surface receptor
GB9917180.3 1999-07-23

Publications (2)

Publication Number Publication Date
WO2001007605A1 WO2001007605A1 (en) 2001-02-01
WO2001007605A8 true WO2001007605A8 (en) 2001-07-12

Family

ID=10857713

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/002652 WO2001007605A1 (en) 1999-07-23 2000-07-10 Immunosuppression by cell surface expression of recombinant cd154

Country Status (4)

Country Link
EP (1) EP1210420A1 (en)
AU (1) AU5996700A (en)
GB (1) GB9917180D0 (en)
WO (1) WO2001007605A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004103333A1 (en) * 2003-05-24 2004-12-02 Juvena (International) Ag Tissue culture media used as a component of cosmetics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7070771B1 (en) * 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US20020127205A1 (en) * 1998-08-31 2002-09-12 Albert Edge Cells expressing immunoregulatory molecules and uses therefor

Also Published As

Publication number Publication date
GB9917180D0 (en) 1999-09-22
AU5996700A (en) 2001-02-13
EP1210420A1 (en) 2002-06-05
WO2001007605A1 (en) 2001-02-01

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