WO2001006226A3 - Methods for determining the proliferation activity of cells - Google Patents

Methods for determining the proliferation activity of cells Download PDF

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Publication number
WO2001006226A3
WO2001006226A3 PCT/EP2000/006656 EP0006656W WO0106226A3 WO 2001006226 A3 WO2001006226 A3 WO 2001006226A3 EP 0006656 W EP0006656 W EP 0006656W WO 0106226 A3 WO0106226 A3 WO 0106226A3
Authority
WO
WIPO (PCT)
Prior art keywords
determining
methods
cells
proliferation activity
relates
Prior art date
Application number
PCT/EP2000/006656
Other languages
German (de)
French (fr)
Other versions
WO2001006226A2 (en
Inventor
Oliver Mueller
Original Assignee
Max Planck Gesellschaft
Oliver Mueller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Oliver Mueller filed Critical Max Planck Gesellschaft
Priority to AU68230/00A priority Critical patent/AU6823000A/en
Publication of WO2001006226A2 publication Critical patent/WO2001006226A2/en
Publication of WO2001006226A3 publication Critical patent/WO2001006226A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • AIDS & HIV (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to methods for determining the proliferation activity of cells by analyzing the concentration and/or the sub-cellular localization of the APC protein in samples and optionally, also determining the functionality of the APC protein. The invention also relates to antibodies, nucleic acids and kits for carrying out the inventive methods.
PCT/EP2000/006656 1999-07-15 2000-07-12 Methods for determining the proliferation activity of cells WO2001006226A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU68230/00A AU6823000A (en) 1999-07-15 2000-07-12 Methods for determining the proliferation activity of cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1999133237 DE19933237A1 (en) 1999-07-15 1999-07-15 Method for determining the proliferation activity of cells
DE19933237.1 1999-07-15

Publications (2)

Publication Number Publication Date
WO2001006226A2 WO2001006226A2 (en) 2001-01-25
WO2001006226A3 true WO2001006226A3 (en) 2001-08-02

Family

ID=7914922

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/006656 WO2001006226A2 (en) 1999-07-15 2000-07-12 Methods for determining the proliferation activity of cells

Country Status (3)

Country Link
AU (1) AU6823000A (en)
DE (1) DE19933237A1 (en)
WO (1) WO2001006226A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10211195B4 (en) * 2002-03-11 2009-01-02 Ipc Process Center Gmbh Dietary supplements

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013103A1 (en) * 1991-01-16 1992-08-06 The Johns Hopkins University Inherited and somatic mutations of apc gene in colorectal cancer of humans
WO1994021814A1 (en) * 1993-03-19 1994-09-29 The Johns Hopkins University Antibodies and assays for determining mutations in the apc gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013103A1 (en) * 1991-01-16 1992-08-06 The Johns Hopkins University Inherited and somatic mutations of apc gene in colorectal cancer of humans
WO1994021814A1 (en) * 1993-03-19 1994-09-29 The Johns Hopkins University Antibodies and assays for determining mutations in the apc gene

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DEKA J ET AL: "THE APC PROTEIN BINDS TO A/T RICH DNA SEQUENCES", ONCOGENE,GB,BASINGSTOKE, HANTS, vol. 18, no. 41, 7 October 1999 (1999-10-07), pages 5654 - 5661, XP000901010, ISSN: 0950-9232 *
DOBASHI YOH ET AL: "Upregulation of the APC gene product during neuronal differentiation of rat pheochromocytoma PC12 cells.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 224, no. 2, 1996, pages 479 - 483, XP000979217, ISSN: 0006-291X *
NEUFELD KRISTI L ET AL: "Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 94, no. 7, 1997, 1997, pages 3034 - 3039, XP000981747, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
AU6823000A (en) 2001-02-05
WO2001006226A2 (en) 2001-01-25
DE19933237A1 (en) 2001-01-18

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