WO2001005821A3 - Viral il-10 for the inhibition of angiogenesis, tumorigenesis and metastasis - Google Patents
Viral il-10 for the inhibition of angiogenesis, tumorigenesis and metastasis Download PDFInfo
- Publication number
- WO2001005821A3 WO2001005821A3 PCT/EP2000/006558 EP0006558W WO0105821A3 WO 2001005821 A3 WO2001005821 A3 WO 2001005821A3 EP 0006558 W EP0006558 W EP 0006558W WO 0105821 A3 WO0105821 A3 WO 0105821A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- viral
- metastasis
- angiogenesis
- tumorigenesis
- inhibition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU58270/00A AU5827000A (en) | 1999-07-16 | 2000-07-11 | Viral il-10 uses |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35483399A | 1999-07-16 | 1999-07-16 | |
US09/354,833 | 1999-07-16 | ||
US16362799P | 1999-11-04 | 1999-11-04 | |
US60/163,627 | 1999-11-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001005821A2 WO2001005821A2 (en) | 2001-01-25 |
WO2001005821A3 true WO2001005821A3 (en) | 2001-07-19 |
Family
ID=26859813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2000/006558 WO2001005821A2 (en) | 1999-07-16 | 2000-07-11 | Viral il-10 for the inhibition of angiogenesis, tumorigenesis and metastasis |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5827000A (en) |
WO (1) | WO2001005821A2 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2295450B1 (en) | 2000-09-29 | 2015-01-28 | Merck Sharp & Dohme Corp. | Pegylated interleukin-10 |
WO2002066069A1 (en) * | 2001-02-20 | 2002-08-29 | Kansai Technology Licensing Organization Co., Ltd. | Remedies for inflammatory/tumor diseases |
ES2606034T3 (en) * | 2006-09-28 | 2017-03-17 | Merck Sharp & Dohme Corp. | Pegylated IL-10 for use in the treatment of lymphoma |
DK2379115T3 (en) | 2008-12-17 | 2018-01-29 | Merck Sharp & Dohme | Preparation and Use of Mono- and Di-PEG-IL-10 |
AU2014254019B2 (en) | 2013-04-18 | 2018-09-27 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
WO2014204816A2 (en) | 2013-06-17 | 2014-12-24 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
CA2920679A1 (en) | 2013-08-30 | 2015-03-05 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
MX2016005915A (en) | 2013-11-11 | 2016-12-16 | Armo Biosciences Inc | Methods of using interleukin-10 for treating diseases and disorders. |
CN106573072A (en) | 2014-06-02 | 2017-04-19 | 阿尔莫生物科技股份有限公司 | Methods of lowering serum cholesterol |
AU2015333827A1 (en) | 2014-10-14 | 2017-04-20 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
CA2963995A1 (en) | 2014-10-22 | 2016-04-28 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
WO2016191587A1 (en) | 2015-05-28 | 2016-12-01 | Armo Biosciences, Inc. | Pegylated interleukin-10 for use in treating cancer |
KR20180038553A (en) | 2015-08-25 | 2018-04-16 | 아르모 바이오사이언시스 인코포레이티드 | Methods for using interleukin-10 to treat diseases and disorders |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992012725A1 (en) * | 1991-01-16 | 1992-08-06 | Schering Corporation | Treatment of neoplastic disease with interleukin-10 |
US5770190A (en) * | 1995-07-14 | 1998-06-23 | Schering Corporation | Method of treatment of acute leukemia with inteleukin-10 |
-
2000
- 2000-07-11 WO PCT/EP2000/006558 patent/WO2001005821A2/en active Application Filing
- 2000-07-11 AU AU58270/00A patent/AU5827000A/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992012725A1 (en) * | 1991-01-16 | 1992-08-06 | Schering Corporation | Treatment of neoplastic disease with interleukin-10 |
US5770190A (en) * | 1995-07-14 | 1998-06-23 | Schering Corporation | Method of treatment of acute leukemia with inteleukin-10 |
Non-Patent Citations (9)
Title |
---|
BENJAMIN DAVID: "Interleukin-10 (IL-10)", CANCER TREATMENT RESEARCH, vol. 80, 1995, pages 305 - 319, XP000979179 * |
BERMAN ROBERT M ET AL: "Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice.", JOURNAL OF IMMUNOLOGY, vol. 157, no. 1, 1996, pages 231 - 238, XP002158947, ISSN: 0022-1767 * |
CERVENAK LASZLO ET AL: "Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10.", BLOOD, vol. 96, no. 7, 1 October 2000 (2000-10-01), pages 2568 - 2573, XP002159072, ISSN: 0006-4971 * |
DE WAAL MALEFYT R ET AL: "THE BIOLOGY OF HUMAN AND VIRAL IL-10", CYTOKINE, vol. 3, no. 5, 1991, pages 500, XP002158949, ISSN: 1043-4666 * |
HUANG SUYUN ET AL: "Interleukin 10 Suppresses Tumor Growth and Metastasis of Human Melanoma Cells : Potential Inhibition of Angiogenesis", CLINICAL CANCER RESEARCH, vol. 2, no. 12, December 1996 (1996-12-01), pages 1969 - 1979, XP000979204 * |
KUNDU NAMITA ET AL: "Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer.", JOURNAL OF THE NATIONAL CANCER INSTITUTE (BETHESDA), vol. 88, no. 8, 1996, pages 536 - 541, XP000979212, ISSN: 0027-8874 * |
RICHTER GUENTHER ET AL: "Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration.", CANCER RESEARCH, vol. 53, no. 18, 1993, pages 4134 - 4137, XP002158948, ISSN: 0008-5472 * |
STEARNS M E ET AL: "IL-10 inhibition of human prostate PC-3 ML cell metastases in SCID mice: IL-10 stimulation of TIMP-1 and inhibition of MMP-2/MMP-9 expression.", INVASION & METASTASIS, vol. 17, no. 2, March 1997 (1997-03-01), pages 62 - 74, XP000979206, ISSN: 0251-1789 * |
STEARNS MARK ET AL: "Interleukin 10 (IL-10) Inhibition of Primary Human Prostate Cell-induced Angiogenesis : IL-10 Stimulation of Tissue Inhibitor of Metalloproteinase-1 and Inhibition of Matrix Metalloproteinase (MMP)-2/MMP-9 Secretion", CLINICAL CANCER RESEARCH, vol. 5, January 1999 (1999-01-01), pages 189 - 196, XP000979198 * |
Also Published As
Publication number | Publication date |
---|---|
AU5827000A (en) | 2001-02-05 |
WO2001005821A2 (en) | 2001-01-25 |
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