WO2001003646A3 - High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units - Google Patents

High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units Download PDF

Info

Publication number
WO2001003646A3
WO2001003646A3 PCT/US2000/019273 US0019273W WO0103646A3 WO 2001003646 A3 WO2001003646 A3 WO 2001003646A3 US 0019273 W US0019273 W US 0019273W WO 0103646 A3 WO0103646 A3 WO 0103646A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical dosage
dosage units
volume
image sensor
composition testing
Prior art date
Application number
PCT/US2000/019273
Other languages
French (fr)
Other versions
WO2001003646A2 (en
Inventor
E Neil Lewis
David J Strachan
Linda H Kidder
Original Assignee
Spectral Dimensions Inc
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/507,293 external-priority patent/US6690464B1/en
Application filed by Spectral Dimensions Inc, Us Health filed Critical Spectral Dimensions Inc
Priority to EP00950359A priority Critical patent/EP1218705A4/en
Publication of WO2001003646A2 publication Critical patent/WO2001003646A2/en
Publication of WO2001003646A3 publication Critical patent/WO2001003646A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/95—Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
    • G01N21/9508—Capsules; Tablets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry

Landscapes

  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

A pharmaceutical dosage unit manufacturing process control apparatus is disclosed. This apparatus includes an image sensor (10), including an array of detector elements, located generally proximate a flow of pharmaceutical dosage units (18). A spectrally selective element (12) simultaneously projects a plurality of spectrally-discrete versions of a same image of the flow of pharmaceutical dosage units onto the image sensor. A spectral processor is responsive to an output of the image sensor.
PCT/US2000/019273 1999-07-14 2000-07-14 High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units WO2001003646A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP00950359A EP1218705A4 (en) 1999-07-14 2000-07-14 High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14380199P 1999-07-14 1999-07-14
US60/143,801 1999-07-14
US09/507,293 US6690464B1 (en) 1999-02-19 2000-02-18 High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units
US09/507,293 2000-02-18

Publications (2)

Publication Number Publication Date
WO2001003646A2 WO2001003646A2 (en) 2001-01-18
WO2001003646A3 true WO2001003646A3 (en) 2001-05-25

Family

ID=26841404

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/019273 WO2001003646A2 (en) 1999-07-14 2000-07-14 High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units

Country Status (2)

Country Link
EP (1) EP1218705A4 (en)
WO (1) WO2001003646A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6894772B2 (en) 2001-02-12 2005-05-17 Analytical Spectral Devices System and method for grouping reflectance data
US6853447B2 (en) 2001-02-12 2005-02-08 Analytical Spectral Devices, Inc. System and method for the collection of spectral image data
US6667802B2 (en) 2001-02-12 2003-12-23 Analytical Spectral Devices, Inc. System and method for self-referencing calibration
US6765212B2 (en) 2001-02-12 2004-07-20 Analytical Spectral Devices, Inc. System and method for combining reflectance data
ATE551596T1 (en) 2003-09-22 2012-04-15 Univ Maryland MEDICINAL AUTHENTICATION
US20060283931A1 (en) * 2003-09-22 2006-12-21 University Of Maryland, Baltimore Product authentication
JPWO2013002291A1 (en) * 2011-06-28 2015-02-23 大塚製薬株式会社 Drug inspection device and drug inspection method
US8964182B2 (en) * 2012-04-13 2015-02-24 Raytheon Company Adaptive multispectral imaging
WO2015136620A1 (en) * 2014-03-11 2015-09-17 株式会社東芝 Tablet inspection device, tablet inspection method, and tablet inspection program
KR20230127227A (en) * 2020-12-03 2023-08-31 지우즈 홀딩 비브이 Inspection of pharmaceutical targets based on hyperspectral imaging
NL2027213B1 (en) * 2020-12-03 2022-07-06 Ziuz Holding B V Inspecting medicine objects based on hyperspectral imaging

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929398A (en) * 1971-08-18 1975-12-30 Harry E Bates High speed optical wavelength detection system
US4278538A (en) * 1979-04-10 1981-07-14 Western Electric Company, Inc. Methods and apparatus for sorting workpieces according to their color signature
US5668373A (en) * 1996-04-26 1997-09-16 Trustees Of Tufts College Methods and apparatus for analysis of complex mixtures

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166755A (en) 1990-05-23 1992-11-24 Nahum Gat Spectrometer apparatus
US5522512A (en) 1994-05-09 1996-06-04 Merck & Co., Inc. System and method for automatically feeding, inspecting and diverting tablets for continuous filling of tablet containers
ATE239913T1 (en) 1997-06-24 2003-05-15 Uhlmann Visiotec Gmbh APPARATUS AND METHOD FOR VERIFYING THE INTEGRITY OF A PRODUCT
DE69841107D1 (en) * 1997-07-12 2009-10-08 Roper Ind Inc MULTISPEKTRAL TWO-DIMENSIONAL IMAGE PROBES SPECTROMETER
SE512098C2 (en) * 1998-05-19 2000-01-24 Agrovision Ab Concentration determination of one component in a mixture of at least two components

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929398A (en) * 1971-08-18 1975-12-30 Harry E Bates High speed optical wavelength detection system
US4278538A (en) * 1979-04-10 1981-07-14 Western Electric Company, Inc. Methods and apparatus for sorting workpieces according to their color signature
US5668373A (en) * 1996-04-26 1997-09-16 Trustees Of Tufts College Methods and apparatus for analysis of complex mixtures

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1218705A4 *

Also Published As

Publication number Publication date
WO2001003646A2 (en) 2001-01-18
EP1218705A2 (en) 2002-07-03
EP1218705A4 (en) 2009-07-29

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