WO2000073446A3 - Adipocyte complement related protein homolog zacrp6 - Google Patents

Adipocyte complement related protein homolog zacrp6 Download PDF

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Publication number
WO2000073446A3
WO2000073446A3 PCT/US2000/014024 US0014024W WO0073446A3 WO 2000073446 A3 WO2000073446 A3 WO 2000073446A3 US 0014024 W US0014024 W US 0014024W WO 0073446 A3 WO0073446 A3 WO 0073446A3
Authority
WO
WIPO (PCT)
Prior art keywords
zacrp6
related protein
protein homolog
complement related
adipocyte complement
Prior art date
Application number
PCT/US2000/014024
Other languages
French (fr)
Other versions
WO2000073446A2 (en
Inventor
Christopher S Piddington
Paul O Sheppard
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU50371/00A priority Critical patent/AU5037100A/en
Publication of WO2000073446A2 publication Critical patent/WO2000073446A2/en
Publication of WO2000073446A3 publication Critical patent/WO2000073446A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to polynucleotide and polypeptide molecules for zacrp6, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in homo and heterotrimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp6 polypeptides.
PCT/US2000/014024 1999-05-27 2000-05-22 Adipocyte complement related protein homolog zacrp6 WO2000073446A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU50371/00A AU5037100A (en) 1999-05-27 2000-05-22 Adipocyte complement related protein homolog zacrp6

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32126299A 1999-05-27 1999-05-27
US09/321,262 1999-05-27

Publications (2)

Publication Number Publication Date
WO2000073446A2 WO2000073446A2 (en) 2000-12-07
WO2000073446A3 true WO2000073446A3 (en) 2001-06-28

Family

ID=23249878

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/014024 WO2000073446A2 (en) 1999-05-27 2000-05-22 Adipocyte complement related protein homolog zacrp6

Country Status (2)

Country Link
AU (1) AU5037100A (en)
WO (1) WO2000073446A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060293225A1 (en) * 2001-07-26 2006-12-28 Genset S.A. Gmg-2 polynucleotides and polypeptides and uses thereof
EP1654279A2 (en) * 2003-08-06 2006-05-10 ZymoGenetics, Inc. Adipocyte complement related protein zacrp12
US9175054B2 (en) * 2011-05-13 2015-11-03 The University Of Tokyo CTRP6 which can be used as therapeutic and prophylactic agent for autoimmune diseases

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039429A2 (en) * 1995-06-05 1996-12-12 Whitehead Institute For Biomedical Research Serum protein produced exclusively in adipocytes
WO1999004000A1 (en) * 1997-07-18 1999-01-28 Zymogenetics, Inc. Adipocyte-specific protein homologs
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
WO1999064629A1 (en) * 1998-06-12 1999-12-16 Smithkline Beecham Corporation Acrp30r2, a homolog of acrp30 (30 kd adipocyte complement-related protein)
WO2000006698A1 (en) * 1998-07-30 2000-02-10 Human Genome Sciences, Inc. 98 human secreted proteins

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039429A2 (en) * 1995-06-05 1996-12-12 Whitehead Institute For Biomedical Research Serum protein produced exclusively in adipocytes
WO1999004000A1 (en) * 1997-07-18 1999-01-28 Zymogenetics, Inc. Adipocyte-specific protein homologs
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
WO1999064629A1 (en) * 1998-06-12 1999-12-16 Smithkline Beecham Corporation Acrp30r2, a homolog of acrp30 (30 kd adipocyte complement-related protein)
WO2000006698A1 (en) * 1998-07-30 2000-02-10 Human Genome Sciences, Inc. 98 human secreted proteins

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 3 August 1996 (1996-08-03), L. HILLIER ET AL: "zi01g09.r1 Soares_fetal_liver_spleen_1NFLS_S1 Homo sapiens cDNA clone IMAGE:429568 5', mRNA sequence.", XP002155109 *
L. HILLIER ET AL: "Generation and analysis of 280,000 human expressed sequence tags", GENOME RESEARCH., vol. 6, no. 9, 1996, COLD SPRING HARBOR LABORATORY PRESS., US, pages 807 - 829, XP000914615, ISSN: 1088-9051 *
SCHERER P E ET AL: "A NOVEL SERUM PROTEIN SIMILAR TO C1Q, PRODUCED EXCLUSIVELY IN ADIPOCYTES", JOURNAL OF BIOLOGICAL CHEMISTRY,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD,US, vol. 270, no. 45, 1 November 1995 (1995-11-01), pages 26746 - 26749, XP000612012, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
AU5037100A (en) 2000-12-18
WO2000073446A2 (en) 2000-12-07

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