WO2000066590A3 - Tetracyclic progesterone receptor modulator compounds and methods - Google Patents
Tetracyclic progesterone receptor modulator compounds and methods Download PDFInfo
- Publication number
- WO2000066590A3 WO2000066590A3 PCT/US2000/011750 US0011750W WO0066590A3 WO 2000066590 A3 WO2000066590 A3 WO 2000066590A3 US 0011750 W US0011750 W US 0011750W WO 0066590 A3 WO0066590 A3 WO 0066590A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- progesterone receptor
- methods
- receptor modulator
- tetracyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU45018/00A AU4501800A (en) | 1999-05-04 | 2000-05-01 | Tetracyclic progesterone receptor modulator compounds and methods |
MXPA01011294A MXPA01011294A (en) | 1999-05-04 | 2000-05-01 | Tetracyclic progesterone receptor modulator compounds and methods. |
CA002371273A CA2371273A1 (en) | 1999-05-04 | 2000-05-01 | Tetracyclic progesterone receptor modulator compounds and methods |
EP00926495A EP1175422A2 (en) | 1999-05-04 | 2000-05-01 | Tetracyclic progesterone receptor modulator compounds and methods |
JP2000615620A JP2002543204A (en) | 1999-05-04 | 2000-05-01 | Tetracyclic progesterone receptor modulatory compounds and methods |
HK02104861.6A HK1043788A1 (en) | 1999-05-04 | 2002-06-28 | Tetracyclic progesterone receptor modulator compounds and methods |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30461499A | 1999-05-04 | 1999-05-04 | |
US60/183,044 | 1999-05-04 | ||
US09/552,353 | 2000-04-19 | ||
US09/552,353 US6358947B1 (en) | 1999-05-04 | 2000-04-19 | Tetracyclic progesterone receptor modulator compounds and methods |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000066590A2 WO2000066590A2 (en) | 2000-11-09 |
WO2000066590A3 true WO2000066590A3 (en) | 2001-02-08 |
Family
ID=26974128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/011750 WO2000066590A2 (en) | 1999-05-04 | 2000-05-01 | Tetracyclic progesterone receptor modulator compounds and methods |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1175422A2 (en) |
CN (1) | CN1353717A (en) |
AU (1) | AU4501800A (en) |
CA (1) | CA2371273A1 (en) |
HK (1) | HK1043788A1 (en) |
WO (1) | WO2000066590A2 (en) |
Families Citing this family (61)
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US8193252B1 (en) | 1999-08-31 | 2012-06-05 | Bayer Pharma AG | Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders |
WO2001015679A2 (en) * | 1999-08-31 | 2001-03-08 | Jenapharm Gmbh & Co. Kg | Mesoprogestins for the treatment and prevention of benign hormone dependent gynecological disorders |
MXPA02002186A (en) * | 1999-08-31 | 2002-09-02 | Jenapharm Gmbh | Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives. |
HK1055058A2 (en) | 2002-10-11 | 2003-12-05 | Ligand Pharm Inc | 5-CYCLOALKENYL 5H-CHROMENO[3,4-f]QUINOLINE DERIVATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS |
CA2501833A1 (en) | 2002-10-11 | 2004-04-22 | Ligand Pharmaceuticals Incorporated | 5-(1',1'-cycloalkyl/alkenyl)methylidene 1,2-dihydro-5h-chromeno[3,4-f]quinolines as selective progesterone receptor modulator compounds |
GB0316290D0 (en) | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
WO2005090282A1 (en) | 2004-03-12 | 2005-09-29 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
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DE102005030294A1 (en) * | 2005-06-24 | 2007-01-04 | Schering Ag | Nonsteroidal progesterone receptor modulators |
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US20120016011A1 (en) | 2009-03-19 | 2012-01-19 | Merck Sharp & Dohme Corp. | RNA Interference Mediated Inhibition of Connective Tissue Growth Factor (CTGF) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
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US20120035247A1 (en) | 2009-03-19 | 2012-02-09 | Merck Sharp & Dohme Corp. | RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 6 (STAT6) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
WO2010111464A1 (en) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
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JP2012521764A (en) | 2009-03-27 | 2012-09-20 | メルク・シャープ・エンド・ドーム・コーポレイション | RNA interference-mediated inhibition of thymic stromal lymphocyte formation factor (TSLP) gene expression using small interfering nucleic acids (siNA) |
WO2010111468A2 (en) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) |
WO2010122089A1 (en) | 2009-04-24 | 2010-10-28 | Glaxo Group Limited | N-pyrazolyl carboxamides as crac channel inhibitors |
EP2421834A1 (en) | 2009-04-24 | 2012-02-29 | Glaxo Group Limited | Pyrazole and triazole carboxamides as crac channel inhibitors |
DK2899191T3 (en) | 2009-04-30 | 2017-11-13 | Glaxo Group Ltd | OXAZOLE-SUBSTITUTED INDAZOLES AS PI3-KINASE INHIBITORS |
EP2507226A1 (en) | 2009-12-03 | 2012-10-10 | Glaxo Group Limited | Novel compounds |
JP2013512880A (en) | 2009-12-03 | 2013-04-18 | グラクソ グループ リミテッド | Indazole derivatives as PI3-kinase inhibitors |
JP2013512879A (en) | 2009-12-03 | 2013-04-18 | グラクソ グループ リミテッド | Benzpyrazole derivatives as inhibitors of PI3 kinase |
US20120272951A1 (en) | 2009-12-16 | 2012-11-01 | 3M Innovative Properties Company | Formulations and methods for controlling mdi particle size delivery |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996019458A2 (en) * | 1994-12-22 | 1996-06-27 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
US5688808A (en) * | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
-
2000
- 2000-05-01 CA CA002371273A patent/CA2371273A1/en not_active Abandoned
- 2000-05-01 EP EP00926495A patent/EP1175422A2/en not_active Ceased
- 2000-05-01 CN CN00808438A patent/CN1353717A/en active Pending
- 2000-05-01 WO PCT/US2000/011750 patent/WO2000066590A2/en not_active Application Discontinuation
- 2000-05-01 AU AU45018/00A patent/AU4501800A/en not_active Abandoned
-
2002
- 2002-06-28 HK HK02104861.6A patent/HK1043788A1/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996019458A2 (en) * | 1994-12-22 | 1996-06-27 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
US5688808A (en) * | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
US5693647A (en) * | 1994-12-22 | 1997-12-02 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
US5693646A (en) * | 1994-12-22 | 1997-12-02 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
Also Published As
Publication number | Publication date |
---|---|
EP1175422A2 (en) | 2002-01-30 |
WO2000066590A2 (en) | 2000-11-09 |
HK1043788A1 (en) | 2002-09-27 |
CN1353717A (en) | 2002-06-12 |
AU4501800A (en) | 2000-11-17 |
CA2371273A1 (en) | 2000-11-09 |
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