WO2000059519A2 - Active agent and combination of active agents for human beings and animals - Google Patents

Active agent and combination of active agents for human beings and animals Download PDF

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Publication number
WO2000059519A2
WO2000059519A2 PCT/DE2000/000929 DE0000929W WO0059519A2 WO 2000059519 A2 WO2000059519 A2 WO 2000059519A2 DE 0000929 W DE0000929 W DE 0000929W WO 0059519 A2 WO0059519 A2 WO 0059519A2
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WO
WIPO (PCT)
Prior art keywords
active ingredient
ingredient combination
extracts
combination according
colostral milk
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PCT/DE2000/000929
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German (de)
French (fr)
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WO2000059519A3 (en
Inventor
Carl-Heinz Kapitz
Gerhard Knapp
Original Assignee
Kapitz Carl Heinz
Gerhard Knapp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from DE1999114646 external-priority patent/DE19914646A1/en
Priority claimed from DE1999163628 external-priority patent/DE19963628A1/en
Priority claimed from DE2000100157 external-priority patent/DE10000157A1/en
Application filed by Kapitz Carl Heinz, Gerhard Knapp filed Critical Kapitz Carl Heinz
Priority to AU47426/00A priority Critical patent/AU4742600A/en
Priority to EP00929249A priority patent/EP1180940A2/en
Publication of WO2000059519A2 publication Critical patent/WO2000059519A2/en
Publication of WO2000059519A3 publication Critical patent/WO2000059519A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206—Colostrum; Human milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/986—Milk; Derivatives thereof, e.g. butter

Definitions

  • the invention relates to an active ingredient and in particular an active ingredient combination for humans and animals, based on colostral milk products and / or colostral milk extracts.
  • Colostral milk or colostrum also known as first or first milk
  • first milk is a secretion of the female mammary glands, usually yellowish due to carotenes, which is often formed during pregnancy, but especially in the first days after birth.
  • Colostrum differs from mature breast milk primarily in its higher protein and vitamin content, especially vitamins A and C, with approximately the same carbohydrate and slightly reduced fat content.
  • Colostrum also has leukocytes loaded with fat drops, the colostrum bodies or colostral bodies.
  • the colostrum which is rich in immunoglobulins, is the first food of the newborn that is important for the first days of life after birth.
  • Health and well-being in humans and animals depend in particular on the food or nutrients ingested and also on how the body processes these substances. These substances can be divided into three different groups of active ingredients. The first shows the substances and active ingredients that are contained in animal products. The second is Mineral group or that of the metal salts with their respective active ingredient content. The third can be assigned to the general plant area. A large number of active ingredients that are contained in the plants are known here.
  • Colostrum of bovine origin has only been available on the market for a few years. It has been possible to gently filter out the valuable ingredients from the colostral milk.
  • the dairy cows produce more colostral milk than the calf needs. Part of the colostral milk is fed to the calves and the other part is brought to the market in a filtered state.
  • Colostral milk extracts are commercially available in the form of granules or as drinkable extracts.
  • Dead Sea Salt extracted from the Dead Sea cleaned and can also be used as a salt bath at home, for example.
  • Dead Sea salt minerals are also used as raw materials for external use in Kos etika.
  • Plant components and / or plant extracts have been known for thousands of years and are used in all areas of health.
  • Active ingredient groups in the individual application are very diverse and still unexplored in many areas, the effectiveness of the three active ingredient groups mentioned above could be demonstrated for internal and external use, especially for the entire skin area.
  • Active ingredient groups contain active ingredients that can have a positive effect on cell metabolism in particular. This has effects in the case of defects in the immune system as well as allergic reactions, skin diseases of various types, neurodermatitis or psoriasis. Furthermore, there are cell regeneration active substances and medicinal substances for the treatment of wounds, sunburn, acne, in the tooth area, skin injuries, all kinds of skin infections, pimples, herpes etc.
  • an active ingredient is now made available which is based on colostral milk products and / or
  • Colostral milk extracts of humans based on sheep and / or goat. Used alone or in the combination of active ingredients explained below, for example as a dietary supplement, food, cosmetic, pharmaceutical and / or as a medicament and as an additive used in cosmetics, beverages, pharmaceuticals, food, nutritional supplements and in the pharmaceutical field, the active ingredient can be used externally and / or are used internally in humans and animals. It has these colostral milk products and / or
  • Human, sheep and / or goat colostrum extracts are significantly different from those of bovine origin and can be used effectively.
  • colostral milk products and / or colostral milk extracts from humans sheep and / or goats in an amount of 0.1 to 60 parts of a hundred, for example
  • Carrier mass ad 100 parts goat colostrum 0.1-60 parts plant extracts 0.1-17 parts testes extracts 0.1-2 parts
  • colostral milk products and / or colostral milk extracts from humans sheep and / or goats are used as food and nutritional supplements according to the invention. These include in particular refreshment and energy drinks and bars with fiber-containing nutrients and fiber.
  • a tablet, powder or capsule form is preferred as a food supplement.
  • Recipe of a capsule as a recipe for a dietary supplement Fruit juice:
  • Vitamin E 2% Vitamin E 5% ß-carotenes 15% colostrum (goat) 35%
  • Formulation of a formulation of an aqueous solution Cream formulation:
  • the present invention further relates to a combination of active substances for human and veterinary use, comprising colostral milk products and / or colostral milk extracts, also of bovine and / or equine origin, in solid, liquid or pasty form or also microencapsulated, in particular enclosed in liposomes; further comprising minerals and / or mineral salts, in particular obtained from the Dead Sea, and further comprising plant components and / or plant extracts, likewise in solid, liquid or pasty form or also microencapsulated, in particular used as a cosmetic, as a medicament, for prophylaxis and therapy Skin irritation of all kinds, as a food, as a food supplement or as a drink, also used as an additive for cosmetics, for medicines, food, food supplements and for beverages.
  • active substances for human and veterinary use comprising colostral milk products and / or colostral milk extracts, also of bovine and / or equine origin, in solid, liquid or pasty form or also microencapsulated, in particular enclosed
  • colostrum The basic components colostrum, minerals, in particular Dead Sea salt, and tea tree oil as a plant extract have so far been used individually in the skin area for skin irritation of all kinds.
  • the active ingredients contained in colostral milk can be taken internally as an extract or as Ointment to be applied externally.
  • the mineral active ingredients used in various skin diseases, especially psoriasis and neurodermatitis, are supplied to humans through a full salt bath through the skin. Not least because of this, sufferers of it travel to the Dead Sea to bathe.
  • the tea tree oil already known as a universal agent, can be used according to experimental studies and clinical studies for burns, mouth and gum infections, cuts and thrush infections. It is also known that colostrum ointment is an excellent remedy for burns and has the reddish spots healed within a very short time.
  • the filtered out colostrum extract or colostrum powder is, apart from small deviations in the substance content, fixed in its composition per liter.
  • Vitamin A ⁇ 150 ⁇ g / 100 ml
  • Vitamin C 270 ⁇ g / 100 ml
  • the mode of action of the colostrum has only been partially researched. So far, it has been found that the growth factors have a positive influence on the cell metabolism and increase the body's immune system.
  • the immunoglobulins support the immune system in preventing and warding off infections and are significantly anti-inflammatory.
  • the amino acids are vital protein building blocks for cellulose change and cell regeneration.
  • Colostrum has special healing properties with regard to skin therapy as a protective substance against bacteria, germs and fungi and leads to a strengthening of the skin tissue.
  • Dead Sea salt Minerals, especially Dead Sea salt, are already present in small amounts in colostral milk, but are not the main focus of colostrum in terms of their importance. In the case of a mixture of colostrum and especially Dead Sea salt, the Dead Sea salt also has its therapeutic effect due to the exceptionally high mine drop content. As with colostrum, the analysis of, for example, Dead Sea salt is fixed down to small deviations per kg.
  • Metal salts in particular obtained from the Dead Sea, are mostly used externally in humans or animals, for example as bath salts, as shampoos, etc. due to their mineral components.
  • Dead Sea salt is particularly valuable for the skin area because it is rich in magnesium and potassium.
  • Magnesium is known as an antiallergen, an important building block for the structural elements of the skin and the enzymes that control the metabolism of the skin. Potassium is an important moisture regulator for the skin. Iodine has a disinfectant and healing effect. Chlorine and sodium are electrolytes dissolved in water and play an important role in
  • Salt concentrations on the skin increases the production of free amino acids.
  • In the foreground of the reactions of the skin metabolism is the activation of proteolytic degradation processes of high-molecular protein compounds.
  • the resulting breakdown products are
  • Peptides with hormone-like effects so that ultimately the ions penetrating the skin can act on the interior of the organism, e.g. on the vascular system, the smooth muscles, on the digestive system and on the autonomic system.
  • the third active ingredient component, plant components and plant extracts also allows countless variation options for the new one due to the large number of plants with their diverse active ingredients in the phyto area
  • Active ingredient combination In particular, because in many cases not only the extract of a plant, but extracts from different plants, in different heights Concentrations, can be used.
  • Aloe Vera strengthens the skin's self-healing
  • avocado oil is soothing and soothing, eucalyptus, geranium, myrrh are antiseptic and antibacterial,
  • Jojoba oil is moisturizing and nourishing, chamomile and lavender are anti-inflammatory,
  • Peppermint oil is cooling and refreshing
  • Sunflower oil contains many vitamins A, D, B and E and has a nourishing effect, tea tree oil is draining and has an antibacterial effect.
  • Colostrum usually has the greatest effect when ingested and its effects are not so long-lasting when used externally.
  • the effect of the Dead Sea salt is particularly good for health when used externally.
  • Colostral milk products and / or colostral milk extracts if these are to be absorbed through the skin, are facilitated and substantially improved by the inventive combination with Dead Sea salt.
  • An improved absorption of the active ingredients of admixed plant extracts is also achieved in this way.
  • colostrum As a natural product, whose unique natural recipe is unlikely to be exactly imitated in laboratories, colostrum has all the vital nonessential and essential amino acids, immunoglobulins and natural growth factors along with vitamins, minerals and lactose and a large number of necessary building materials Fuel substances for the preservation and protection of life.
  • Minerals and / or mineral salts in particular Dead Sea salt as a mineral donor that is unique in the world, complement the minerals that do not contain or only to a small extent in colostrum by a further building block for health, which can affect the entire metabolism of humans, in particular through the skin .
  • the active ingredient combination according to the invention is supplemented by herbal extracts and extracts, and their various modes of action are also used.

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Abstract

Disclosed is an active agent for human beings and animals. Said active agent is based on colostrum of human beings, sheep and/or goats. The invention also relates to a combination of active agents, whereby said combination consists of colostrum and/or colostrum extracts in the solid, liquid, pasty or microcapsulated form. The combination also consists of minerals and mineral salts, especially obtained from the Dead Sea, plant components and/or plant extracts in the solid, liquid or pasty form. The active agents are used as cosmetics, medicaments, especially for the prophylaxis and therapy of skin diseases, as an aid in infections, for strengthening the immune system, as food, as food supplements and in the pharmaceutical field or as an additive in food, cosmetics, medicaments, food supplements or drinks.

Description

Wirkstoff und Wirkstoffkombination für Mensch und TierActive ingredient and combination of active ingredients for humans and animals
Beschreibung:Description:
Die Erfindung betrifft einen Wirkstoff und insbesondere eine Wirkstoffkombination für Mensch und Tier, basierend auf Kolostralmilchprodukten und/oder Kolostralmilchauszügen.The invention relates to an active ingredient and in particular an active ingredient combination for humans and animals, based on colostral milk products and / or colostral milk extracts.
Kolostralmilch oder Kolostrum, auch als Vor- oder Erstmilch bezeichnet, ist ein zumeist durch Karotine gelblich gefärbtes Sekret der weiblichen Brustdrüsen, das oft schon während der Schwangerschaft, besonders jedoch in den ersten Tagen nach der Geburt gebildet wird. Das Kolostrum unterscheidet sich von der reifen Muttermilch vor allem durch einen höheren Gehalt an Proteinen und Vitaminen, vor allem Vitamine A und C, bei etwa gleichem Kohlenhydrat- und etwas verminderten Fettgehalt. Weiter weist Kolostrum mit Fetttropfen beladene Leukozyten, die Kolostrum-Körperchen oder Kolostralkörperchen auf. Das an Immunglobuline reiche Kolostrum ist nach der Geburt die erste, für die ersten Lebenstage wichtige Nahrung des Neugeborenen.Colostral milk or colostrum, also known as first or first milk, is a secretion of the female mammary glands, usually yellowish due to carotenes, which is often formed during pregnancy, but especially in the first days after birth. Colostrum differs from mature breast milk primarily in its higher protein and vitamin content, especially vitamins A and C, with approximately the same carbohydrate and slightly reduced fat content. Colostrum also has leukocytes loaded with fat drops, the colostrum bodies or colostral bodies. The colostrum, which is rich in immunoglobulins, is the first food of the newborn that is important for the first days of life after birth.
Gesundheit und Wohlbefinden bei Mensch und Tier sind insbesondere von der aufgenommenen Nahrung bzw. Nahrungsstoffen abhängig und gleichermaßen davon, wie der Körper diese Stoffe aufbereitet. Diese Stoffe können in drei verschiedenen Wirkstoffgrüppen eingeteilt werden. Die erste weist die Stoffe und Wirkstoffe auf, die in tierischen Produkten enthalten sind. Die zweite ist die Mineralstoffgruppe bzw. die der Metallsalze mit ihrem jeweiligen Wirkstoffgehalt. Die dritte kann dem allgemeinen Pflanzenbereich zugeordnet werden. Hier ist eine große Anzahl an Wirkstoffen bekannt, die in den Pflanzen enthalten sind.Health and well-being in humans and animals depend in particular on the food or nutrients ingested and also on how the body processes these substances. These substances can be divided into three different groups of active ingredients. The first shows the substances and active ingredients that are contained in animal products. The second is Mineral group or that of the metal salts with their respective active ingredient content. The third can be assigned to the general plant area. A large number of active ingredients that are contained in the plants are known here.
Bisher wurden alle drei Wirkstoffgruppen allein verarbeitet und verwendet.So far, all three drug groups have been processed and used alone.
Erst seit ein paar Jahren ist Kolostrum bovinen Ursprungs auf dem Markt erhältlich. Es ist gelungen, aus der Kolostralmilch die wertvollen Inhaltsstoffe schonend herauszufiltern. Die Milchkühe produzieren mehr Kolostralmilch, als das Kalb benötigt. Ein Teil der Kolostralmilch wird den Kälbern zugeführt und der andere Teil wird filtriert in den Markt gebracht. Im Handel sind die Kolostralmilchauszüge in Form von Granulaten oder als trinkbare Extrakte erhältlich.Colostrum of bovine origin has only been available on the market for a few years. It has been possible to gently filter out the valuable ingredients from the colostral milk. The dairy cows produce more colostral milk than the calf needs. Part of the colostral milk is fed to the calves and the other part is brought to the market in a filtered state. Colostral milk extracts are commercially available in the form of granules or as drinkable extracts.
Die bekannten Totes Meer Salz Produkte wurden erst in jüngster Zeit bekannt, obwohl schon den Römern das Baden im Toten Meer als besonders heilend bekannt war. Heute wird dasThe well-known Dead Sea salt products have only recently become known, although bathing in the Dead Sea was already known to the Romans as particularly healing. Today it will
Salz aus dem Toten Meer gewonnen, gereinigt und kann als Salzbad bspw. auch zu Hause eingesetzt werden. Totes Meer Salz Mineralien werden auch als Grundstoffe für die äußerliche Anwendung in Kos etika verwendet.Salt extracted from the Dead Sea, cleaned and can also be used as a salt bath at home, for example. Dead Sea salt minerals are also used as raw materials for external use in Kos etika.
Pflanzenbestandteile und/oder Pflanzenauszüge sind seit Jahrtausenden bekannt und werden in allen Gesundheitsbereichen angewendet.Plant components and / or plant extracts have been known for thousands of years and are used in all areas of health.
Obwohl die Wirkungsweise der drei vorgenanntenAlthough the operation of the three above
Wirkstoffgruppen in der einzelnen Anwendung sehr vielfältig und in vielen Bereichen noch unerforscht ist, konnte die Wirksamkeit der drei oben genannten Wirkstoffgruppen bei einer innerlichen und äußerlichen Anwendung insbesondere für den gesamten Hautbereich nachgewiesen werden.Active ingredient groups in the individual application are very diverse and still unexplored in many areas, the effectiveness of the three active ingredient groups mentioned above could be demonstrated for internal and external use, especially for the entire skin area.
Allgemein ist festzustellen, daß die Erkrankungen im Hautbereich drastisch zunehmen. Wenn Organe oder allgemein der Stoffwechsel Probleme aufzeigt, ist als Reaktion vielfach auch die Haut stark betroffen. Es wird dann versucht, Hautprobleme durch äußere Anwendung von bspw. Kosmetika zu beheben, womit Symptome, nicht jedoch die Ursachen der Probleme behandelt werden.In general it can be said that the diseases in the skin area increase drastically. If organs or general the metabolism shows problems, the skin is often affected as a reaction. An attempt is then made to remedy skin problems by external use of, for example, cosmetics, with which symptoms but not the causes of the problems are dealt with.
Es ist seit längerem bekannt, daß in allen dreiIt has long been known that in all three
Wirkstoffgruppen Wirkstoffe enthalten sind, die insbesondere den Zellstoffwechsel positiv beeinflussen können. Das hat Auswirkungen bei Defekten des Immunsystems wie auch bei allergischen Reaktionen, Hautkrankheiten verschiedener Art, Neurodermitis oder Psoriasis. Desweiteren finden sich bei allen drei Wirkstoffgruppen fördernde Zellregenerierungswirkstoffe und Heilstoffe für die Behandlung von Wunden, Sonnenbrand, Akne, im Zahnbereich, von Hautverletzungen, von Hautinfektionen aller Art, von Pickeln, von Herpes usw.Active ingredient groups contain active ingredients that can have a positive effect on cell metabolism in particular. This has effects in the case of defects in the immune system as well as allergic reactions, skin diseases of various types, neurodermatitis or psoriasis. Furthermore, there are cell regeneration active substances and medicinal substances for the treatment of wounds, sunburn, acne, in the tooth area, skin injuries, all kinds of skin infections, pimples, herpes etc.
Nach der Erfindung wird nunmehr ein Wirkstoff zur Verfügung gestellt, der auf Kolostralmilchprodukten und/oderAccording to the invention, an active ingredient is now made available which is based on colostral milk products and / or
Kolostralmilchauszügen des Menschen, von Schaf und/oder Ziege basiert. Eingesetzt für sich allein oder in der nachstehend erläuterten Wirkstoffkombination, bspw. als Nahrungsergänzungsmittel, Nahrungsmittel, Kosmetikum, Arzneimittel und/oder als Medikament sowie als Zusatz verwendet bei Kosmetika, Getränken, Arzneimitteln, Nahrungsmitteln, Nahrungsergänzungs itteln und in dem pharmazeutischen Bereich kann der Wirkstoff äußerlich und/oder innerlich bei Mensch und Tier Anwendung finden. Es weisen diese Kolostralmilchprodukte und/oderColostral milk extracts of humans, based on sheep and / or goat. Used alone or in the combination of active ingredients explained below, for example as a dietary supplement, food, cosmetic, pharmaceutical and / or as a medicament and as an additive used in cosmetics, beverages, pharmaceuticals, food, nutritional supplements and in the pharmaceutical field, the active ingredient can be used externally and / or are used internally in humans and animals. It has these colostral milk products and / or
Kolostralmilchauszüge des Menschen, von Schaf und/oder Ziege signifikante Unterschiede gegenüber denen bovinen Ursprungs auf und können wirksam verwendet werden.Human, sheep and / or goat colostrum extracts are significantly different from those of bovine origin and can be used effectively.
Insbesondere hat es sich als zweckmäßig erwiesen,In particular, it has proven to be useful
Kolostralmilchprodukte und/ öder Kolostralmilchauszüge des Menschen, von Schaf und/oder Ziege in einer Menge von 0,1 bis 60 Teilen von Hundert als Zusatz zu verwenden, beispielsweiseTo use colostral milk products and / or colostral milk extracts from humans, sheep and / or goats in an amount of 0.1 to 60 parts of a hundred, for example
Trägermasse ad 100 Teile Ziegenkolostrum 0,1 - 60 Teile Pflanzenextrakte 0,1 - 17 Teile Testesextrakte 0,1 - 2 TeileCarrier mass ad 100 parts goat colostrum 0.1-60 parts plant extracts 0.1-17 parts testes extracts 0.1-2 parts
Gleichfalls in Teilen zwischen 0,1 - 60 von Hundert finden nach der Erfindung Kolostralmilchprodukte und/oder Kolostralmilchauszüge des Menschen, von Schaf und/oder Ziege Verwendung als Nahrungs- und Nahrungsergänzungsmittel Verwendung. Hierzu zählen insbesondere Erfrischungs- und Energiegetränke und Riegel mit faserhaltigen Nähr- und Ballaststoffen. Als Nahrungsergänzungsmittel ist eine Tabletten-, Pulver- oder Kapselform bevorzugt.Likewise, in parts between 0.1-60 of a hundred, colostral milk products and / or colostral milk extracts from humans, sheep and / or goats are used as food and nutritional supplements according to the invention. These include in particular refreshment and energy drinks and bars with fiber-containing nutrients and fiber. A tablet, powder or capsule form is preferred as a food supplement.
Beispiele :Examples:
Rezeptur einer Kapsel als Rezeptur für einen Nahrungsergänzungsmittel : Fruchtsaft:Recipe of a capsule as a recipe for a dietary supplement: Fruit juice:
Pflanzenextrakte 30 % Fruchtsaftkonzentrat 25 %Plant extracts 30% fruit juice concentrate 25%
Vitamin C 5 % Vitamin C 5 %Vitamin C 5% Vitamin C 5%
Vitamin E 2 % Vitamin E 5 % ß-Carotine 15 % Kolostrum (Ziege) 35 %Vitamin E 2% Vitamin E 5% ß-carotenes 15% colostrum (goat) 35%
Kolostrum (Ziege) 22 % Magnesiumsalze 5 %Colostrum (goat) 22% magnesium salts 5%
Magnesiumsalze 4 % Natriumsalze 2 %Magnesium salts 4% Sodium salts 2%
Natriumsalze 4 % Hilfsstoffe 12 %Sodium salts 4% auxiliary 12%
Hilfsstoffe ad 100 Aqua ad 100Excipients ad 100 Aqua ad 100
Rezeptur einer Rezeptur einer wässrigen Lösung: Creme-Formulierung:Formulation of a formulation of an aqueous solution: Cream formulation:
Aqua ad 100 Aqua ad 100Aqua ad 100 Aqua ad 100
Cetrimonium Chloride 0,08 % Butyrum CapraeCetrimonium Chloride 0.08% Butyrum Caprae
Panthenol 0,6b % (Kolostrum) 12,0 %Panthenol 0.6b% (colostrum) 12.0%
Hydrolized Wheat Aloe Barbadensis 6,0 % Protein 2,16 % Calendula Officinalis 0, 6Hydrolized Wheat Aloe Barbadensis 6.0% Protein 2.16% Calendula Officinalis 0.6
Propylene Glycol 1,05 % Urtica Dioica 0,6 %Propylene Glycol 1.05% Urtica Dioica 0.6%
Betula Alba 0,60 % Spirulina Pacifica 6,0 %Betula Alba 0.60% Spirulina Pacifica 6.0%
Urtica Dioica 0,60 % Magnesium Chloride 3,5 %Urtica Dioica 0.60% Magnesium Chloride 3.5%
Hedera Helix 0,60 % Magnesium Sulfate 3,5 %Hedera Helix 0.60% magnesium sulfate 3.5%
Magnesium Chloride 3,50 % Sodium Chloride 3,5 %Magnesium Chloride 3.50% Sodium Chloride 3.5%
Sodiu Chloride 3,00 % Caprylic/CapricSodiu Chloride 3.00% Caprylic / Capric
Butyrum Caprae Triglyceride 15,4%Butyrum Caprae Triglyceride 15.4%
(Kolostrum) 3,50 % KOH (10%-ig) 0,4 %(Colostrum) 3.50% KOH (10%) 0.4%
Parfüm 0,20 % Citric Acid 0,6 %Perfume 0.20% Citric Acid 0.6%
Methylparabene 0,20 % MethyldibromoMethyl parabens 0.20% methyl dibromo
Propylparabene 0,20 % Glutaronitrile 0,5 %Propylparabens 0.20% Glutaronitrile 0.5%
Magnesium Sulfate 2,85 % Panthenol 0,2 %Magnesium sulfates 2.85% panthenol 0.2%
Allantoin 0,1 %Allantoin 0.1%
Rezeptur für eine Rezeptur für Tiernahrung: Lotion:Formula for a formula for pet food: Lotion:
Aqua ad 100 Fleischkonzentrate 55 Sorbitol 2,55 % Kolostrum 35 Carbomer 0,02 % Magnesiumsalze 5 Citrus Dulcis 0,30 % Pflanzenextrakte 5Aqua ad 100 meat concentrates 55 sorbitol 2.55% colostrum 35 carbomer 0.02% magnesium salts 5 citrus dulcis 0.30% plant extracts 5
Acrylates/C 10 - C 30 AlkylAcrylates / C 10 - C 30 alkyl
Acrylates Crosspolymer 0,26 Glycerylstearate Ceteareth-20, Ceteareth-12 Cetearyl AlcoholAcrylates Crosspolymer 0.26 Glyceryl Stearate Ceteareth-20, Ceteareth-12 Cetearyl Alcohol
Cetyl Palmitate 2,95 Butyrum CapraeCetyl Palmitate 2.95 Butyrum Caprae
(Kolostrum) 6,30(Colostrum) 6.30
Urtica Dioica 0,60Urtica Dioica 0.60
Hedera Helix 0,60Hedera Helix 0.60
Calendula Officinalis 0,60Calendula Officinalis 0.60
Magnesium Chloride 3,50Magnesium chloride 3.50
Magnesium Sulfate 3 , 50Magnesium sulfates 3, 50
Sodium Chloride 3,50Sodium chloride 3.50
Aloe Barbadensis 0,30Aloe barbadensis 0.30
Methylparabene 0,30 Propylparabene 0,30 %Methyl parabens 0.30 Propyl parabens 0.30%
Parfüm 0,02 %Perfume 0.02%
Die vorliegende Erfindung betrifft weiter eine Wirkstoffkombination für den Human- und Veterinärbereich, aufweisend Kolostralmilchprodukte und/oder Kolostralmilchauszüge, auch bovinen und/oder equinen Ursprungs, in fester, flüssiger oder pastöser Form oder auch mikroverkapselt, insbesondere in Liposomen eingeschlossen; weiter aufweisend Mineralien und/oder Mineralsalze, insbesondere aus dem Toten Meer gewonnen, und weiter aufweisend Pflanzenbestandteile und/oder Pflanzenauszüge, gleichfalls jeweils in fester, flüssiger oder pastöser Form oder auch mikroverkapselt, insbesondere eingesetzt als Kosmetikum, als Arzneimittel, zur Prophylaxe und Therapie bei Hautirritationen aller Art, als Nahrungsmittel, als Nahrungsergänzungsmittel oder als Getränk, verwendet auch als Zusatz für Kosmetika, für Arzneimittel, Nahrungsmittel, Nahrungsergänzungsmittel und bei Getränken.The present invention further relates to a combination of active substances for human and veterinary use, comprising colostral milk products and / or colostral milk extracts, also of bovine and / or equine origin, in solid, liquid or pasty form or also microencapsulated, in particular enclosed in liposomes; further comprising minerals and / or mineral salts, in particular obtained from the Dead Sea, and further comprising plant components and / or plant extracts, likewise in solid, liquid or pasty form or also microencapsulated, in particular used as a cosmetic, as a medicament, for prophylaxis and therapy Skin irritation of all kinds, as a food, as a food supplement or as a drink, also used as an additive for cosmetics, for medicines, food, food supplements and for beverages.
Insbesondere mit der Mischung von Kolostralmilchprodukten und/oder Kolostralmilchauszügen als tierische Produkte, von Mineralien und/oder Mineralsalzen als ErdwirkstoffSubstanzen, besonders wegen des hohen Mineralgehalts bevorzugt aus dem Toten Meer gewonnen, und von Pflanzenbestandteilen und/oder Pflanzenextrakten mit den vielfältigen pflanzlichen Wirkstoffen ist eine erfinderische Kombination von lebenserhaltenden und heilenden Grundstoffen gefunden worden.In particular with the mixture of colostral milk products and / or colostral milk extracts as animal products, of minerals and / or mineral salts as earth active substance substances, particularly because of the high mineral content, preferably obtained from the Dead Sea, and of plant constituents and / or plant extracts with the diverse plant active substances is an inventive one Combination of life-sustaining and healing ingredients have been found.
Die Erfindung wird anhand eines Verwendungsbeispiel weiter erläutert:The invention is further explained using an example of use:
Die Grundkomponenten Kolostrum, Mineralien, insbesondere Totes Meer Salz, und als Pflanzenauszug Teebaumöl sind bisher jeweils einzeln für sich im Hautbereich bei Hautirritationen verschiedenster Art eingesetzt worden. Die in der Kolostralmilch enthaltenden Wirkstoffe können, je nach Anwendungsform, als Extrakt innerlich eingenommen oder als Salbe äußerlich aufgetragen werden. Die Mineralienwirkstoffe, eingesetzt bei verschiedenen Hautkrankheiten, insbesondere bei Psoriasis und bei Neurodermitis , werden dem Menschen durch ein Salzvollbad über die Haut zugeführt. Nichtzuletzt deshalb reisen auch daran Erkrankte zum Baden an das Tote Meer. Das schon als Universalmittel bezeichnete Teebaumöl kann nach experimentellen Untersuchungen und nach klinischen Studien bei Verbrennungen, Mund- und Zahnfleischentzündungen, Schnittwunden sowie Soor-Infektionen eingesetzt werden. Es ist gleichfalls bekannt, daß Kolostrumsalbe ein hervorragendes Mittel gegen Verbrennungen ist und innerhalb kürzester Zeit die rötlichen Stellen abheilen läßt.The basic components colostrum, minerals, in particular Dead Sea salt, and tea tree oil as a plant extract have so far been used individually in the skin area for skin irritation of all kinds. Depending on the form of application, the active ingredients contained in colostral milk can be taken internally as an extract or as Ointment to be applied externally. The mineral active ingredients used in various skin diseases, especially psoriasis and neurodermatitis, are supplied to humans through a full salt bath through the skin. Not least because of this, sufferers of it travel to the Dead Sea to bathe. The tea tree oil, already known as a universal agent, can be used according to experimental studies and clinical studies for burns, mouth and gum infections, cuts and thrush infections. It is also known that colostrum ointment is an excellent remedy for burns and has the reddish spots healed within a very short time.
Diese bisher einzeln gegen Verbrennungen und Hautschäden jeder Art angewendeten Komponenten Kolostrum, Totes Meer Salz und Teebaumöl können erfindungsgemäß in Form einer einzigen Salbe zusammengestellt werden, die aus mit l%igen Totes Meer Salz Mineralien, aus Kolostrumpulver und Teebaumöl besteht.These components of colostrum, Dead Sea salt and tea tree oil, which have hitherto been used individually against burns and skin damage of all kinds, can be put together according to the invention in the form of a single ointment which consists of minerals with 1% Dead Sea salt, colostrum powder and tea tree oil.
Bei der erfindungsgemäßen Wirkstoffkombination aus diesen drei Wirkstoffgruppen entsteht eine Wechselwirkung der Gruppen, die bei geeigneter Abstimmung aufeinander einen Synergieefekt auslösen und damit sowohl bei einer oralen Einnahme als auch bei einer äußerlichen Anwendung eine verstärkte Heilwirkung hervorrufen, verstärkt gegenüber einerIn the combination of active substances according to the invention from these three active substance groups, there is an interaction of the groups which, when suitably coordinated with one another, trigger a synergy effect and thus produce an increased healing effect both when taken orally and when used externally, in comparison to one
Einzelverabreichung.Single administration.
Aus DE 296 23 125.8 und DE 196 19 990 ist es bekannt, nach Entkaseinierung der Kolostralmilch vom Rind die Wirkstoffe auszufiltern und für Mensch und Tier einnehmbar zu machen.From DE 296 23 125.8 and DE 196 19 990 it is known to filter out the active ingredients after decaseinizing the colostral milk from cattle and to make them accessible to humans and animals.
Das ausgefilterte Kolostrum-Extrakt oder Kolostrum-Pulver ist, bis auf kleine Abweichungen im Stoffgehalt, in seiner Zusammensetzung pro Liter feststehend.The filtered out colostrum extract or colostrum powder is, apart from small deviations in the substance content, fixed in its composition per liter.
Analyse des Kolostrumextraktes bovinen UrsprungsAnalysis of colostrum extract of bovine origin
Energiegehalt 80,0 kj/lOOg pH 6,16 Osmolarität 418 mθsm/kgEnergy content 80.0 kj / 100 g pH 6.16 Osmolarity 418 mθsm / kg
Gesamtprotein 7,25 g/lOOmlTotal protein 7.25 g / 100 ml
Trockensubstanz 8,36 g/lOOmlDry substance 8.36 g / 100 ml
Asche 0,68 g/100mlAsh 0.68 g / 100ml
Laktose 0,2 g/ 100mlLactose 0.2 g / 100ml
Glukose 1,23 g/lOOmlGlucose 1.23 g / 100 ml
Kohlehydrate 3,8 g/lOOmlCarbohydrates 3.8 g / 100 ml
Fett <0,03 g/lOOmlFat <0.03 g / 100 ml
VITAMINEVITAMINS
Vitamin A <150 μg/lOOmlVitamin A <150 μg / 100 ml
Thiamin ( Vit. Bl) 69,6 μg/lOOmlThiamine (Vit.Bl) 69.6 μg / 100 ml
Riboflavin ( Vit. B2 ) 268,2 μg/lOOml Pyrodoxin ( Vit. B6 ) 17,88 μg/lOOmlRiboflavin (Vit. B2) 268.2 μg / 100 ml pyrodoxine (Vit. B6) 17.88 μg / 100 ml
Cobala in ( Vit. B12) 0,062 μg/lOOmlCobala in (Vit.B12) 0.062 μg / 100 ml
Folsäure 4,9 μg/lOO lFolic acid 4.9 μg / 100 l
Vitamin C 270 μg/lOOmlVitamin C 270 μg / 100 ml
Cholecalciferol ( D3 ) 0,28 μg/lOOml Tocopherol ( Vit. E ) 30 μg/lOOmlCholecalciferol (D3) 0.28 μg / 100 ml tocopherol (Vit. E) 30 μg / 100 ml
Ubichinon 5,4 μg/ 100mlUbiquinone 5.4 μg / 100ml
MINERALIENMINERALS
Natrium ( Na ) 1344,7mg/l Kalium ( K ) 1883, 5 mg/1 Kalzium ( Ca ) 417,42mg/l Magnesium ( Mg ) 163,72mg/l Eisen ( Fe ) 0,29 mg/1 Kupfer ( Cu ) 0,06 mg/1 Zink ( Zn ) 0,06 mg/1 Chrom ( Cr ) 0,01 mg/1 Phosphor ( P- ) 498^0 mg/1 Selen ( Se ) 0,003 mg/ NATURLICHE WACHSTUMSFAKTORENSodium (Na) 1344.7 mg / l potassium (K) 1883, 5 mg / 1 calcium (Ca) 417.42 mg / l magnesium (Mg) 163.72 mg / l iron (Fe) 0.29 mg / 1 copper (Cu ) 0.06 mg / 1 zinc (Zn) 0.06 mg / 1 chromium (Cr) 0.01 mg / 1 phosphorus (P-) 498 ^ 0 mg / 1 selenium (Se) 0.003 mg / NATURAL GROWTH FACTORS
IGF-1 280 μg/1IGF-1 280 μg / 1
IGF-2 190 μg/1
Figure imgf000011_0001
IGF-2 190 µg / 1
Figure imgf000011_0001
FREIE AMINOSÄURENFREE AMINO ACIDS
Alanin 7,92 mg/1Alanine 7.92 mg / 1
Arginin 6,72 mg/1Arginine 6.72 mg / 1
Asparginsäure 3,19 mg/1 ß-Alanin <0,32 mg/1 ß-Aminoisobuttersäure 1,24 mg/1Aspartic acid 3.19 mg / 1 ß-alanine <0.32 mg / 1 ß-aminoisobutyric acid 1.24 mg / 1
Citrullin 1,26 mg/1Citrulline 1.26 mg / 1
Cystin <0,32 mg/1Cystine <0.32 mg / 1
Glutamin 8,77 mg/1Glutamine 8.77 mg / 1
Glutaminsäure 44,4 mg/1Glutamic acid 44.4 mg / 1
Glycin 5,82 mg/1Glycine 5.82 mg / 1
Histidin 1,68 mg/1Histidine 1.68 mg / 1
Isoleucin 5,82 mg/1Isoleucine 5.82 mg / 1
Leucin 11,33 mg/1Leucine 11.33 mg / 1
Lysin 9,59 mg/1Lysine 9.59 mg / 1
Methionin 1,2 mg/1Methionine 1.2 mg / 1
Omithin 0,64 mg/1Omithin 0.64 mg / 1
Phenylalanin 5,94 mg/1Phenylalanine 5.94 mg / 1
Phosphorethanolamin 32,84 mg/1Phosphorethanolamine 32.84 mg / 1
Phosphorserin 10,87 mg/lPhosphorus serine 10.87 mg / l
Prolin 8,84 mg/1Proline 8.84 mg / 1
Serin 6,05 mg/1Serine 6.05 mg / 1
Taurin 138,0 mg/1Taurine 138.0 mg / 1
Threonin 3,73 mg/1Threonine 3.73 mg / 1
Tryptophan 7,32 mg/1Tryptophan 7.32 mg / 1
Tyrosin 3,91 mg/1Tyrosine 3.91 mg / 1
Valin 13,36 mg/1Valine 13.36 mg / 1
IMMUNOGLOBULINE IgG 60 g/ i IgA 6 g/ i IgM 12 g/ iIMMUNOGLOBULINE IgG 60 g / i IgA 6 g / i IgM 12 g / i
ORGANISCHE MOLEKÜLEORGANIC MOLECULES
Kreatinin 44,7 mg/1Creatinine 44.7 mg / 1
Kreatin 165,1 mg/1Creatine 165.1 mg / 1
Aufgrund der Vielfalt seiner Inhaltsstoffe ist die Wirkungsweise des Kolostrums nur zum Teil erforscht worden. Bisher konnte festgestellt werden, daß die Wachstumsfaktoren einen positiven Einfluß auf den Zellstoffwechsel nehmen und eine Steigerung der körpereigenen Immunabwehr erreichen.Due to the variety of its ingredients, the mode of action of the colostrum has only been partially researched. So far, it has been found that the growth factors have a positive influence on the cell metabolism and increase the body's immune system.
Die Immunglobuline ( Antikörper ) unterstützen das Immunsystem bei Vorbeugung und Abwehr von Infektionen und sind maßgeblich entzündungshemmend.The immunoglobulins (antibodies) support the immune system in preventing and warding off infections and are significantly anti-inflammatory.
Die Aminosäuren sind lebenswichtige Eiweißbausteine für den ZellstoffWechsel und der Zellregeneration.The amino acids are vital protein building blocks for cellulose change and cell regeneration.
Alle Wirkstoffe sind wasserlöslich.All active ingredients are water soluble.
Kolostrum hat besondere heilende Eigenschaften hinsichtlich einer Hauttherapie als Schutzstoff gegenüber Bakterien, Keimen und Pilzen und führt zu einer Stärkung des Hautgewebes .Colostrum has special healing properties with regard to skin therapy as a protective substance against bacteria, germs and fungi and leads to a strengthening of the skin tissue.
Mineralstoffe, insbesondere Totes Meer Salz, sind in geringen Mengen bereits in der Kolostralmilch vorhanden, stehen in Bezug auf ihre Bedeutung jedoch beim Kolostrum nicht im Vordergrund. Bei einer Mischung von Kolostrum und insbesondere Totes Meer Salz entfaltet aufgrund des außergewöhnlich hohen Minefalgehaltes auch das Totes Meer Salz seine therapeutische Wirkung. Wie bei dem Kolostrum ist auch die Analyse beispielsweise von Totes Meer Salz bis auf kleine Abweichungen pro kg feststehend.Minerals, especially Dead Sea salt, are already present in small amounts in colostral milk, but are not the main focus of colostrum in terms of their importance. In the case of a mixture of colostrum and especially Dead Sea salt, the Dead Sea salt also has its therapeutic effect due to the exceptionally high mine drop content. As with colostrum, the analysis of, for example, Dead Sea salt is fixed down to small deviations per kg.
Analyse des Toten Meer SalzesAnalysis of the Dead Sea salt
KATIONENCATIONS
Natrium ( Na ) 74300 mg/kgSodium (Na) 74300 mg / kg
Kalium ( K ) 162000 mg/kgPotassium (K) 162000 mg / kg
Ammonium 310 mg/kgAmmonium 310 mg / kg
Magnesium 102000 mg/kgMagnesium 102000 mg / kg
Calcium 1760 mg/kgCalcium 1760 mg / kg
Strontium 175 mg/kgStrontium 175 mg / kg
Mangan 6,8 mg/kgManganese 6.8 mg / kg
Eisen 45 mg/kgIron 45 mg / kg
ANIONENANIONS
Fluorid 35 mg/kgFluoride 35 mg / kg
Chlorid 557000 mg/kgChloride 557000 mg / kg
Bromid 5100 mg/kgBromide 5100 mg / kg
Jodid 14 mg/kgIodide 14 mg / kg
Sulfat 460 mg/kgSulfate 460 mg / kg
Hydrogenphi Dsphat 34 mg/kgHydrogenphi Dsphat 34 mg / kg
Hydrogencarbonat 770 mg/kgHydrogen carbonate 770 mg / kg
Carbonat 2430 mg/kgCarbonate 2430 mg / kg
Summe 906440 mg/kgTotal 906 440 mg / kg
undissoziierte Stoffe meta-Kieselsäure 3450 mg/kgundissociated substances meta-silica 3450 mg / kg
Gelöste feste Bestandteile 909890 mg/kg Rest FeuchtigkeitDissolved solid components 909890 mg / kg Residual moisture
Metallsalze, insbesondere aus dem Toten Meer gewonnen, werden aufgrund ihrer Mineralbestandteile meistens äußerlich bei Menschen oder Tieren bspw. als Badesalz, als Shampoo, etc. verwendet.Metal salts, in particular obtained from the Dead Sea, are mostly used externally in humans or animals, for example as bath salts, as shampoos, etc. due to their mineral components.
Totes Meer Salz ist besonders wertvoll für den Hautbereich, da es reich an Magnesium und Kalium ist. Magnesium ist als Antiallergen bekannt, ein wichtiger Baustein für die Strukturelemente der Haut und der Enzyme, die den Stoffwechsel der Haut steuern. Kalium ist ein wichtiger Feuchtigkeitsregulator für die Haut. Jod wirkt desinfizierend und abheilend. Chlor und Natrium sind in Wasser gelöste Elektrolyte und spielen eine wichtige Rolle bei derDead Sea salt is particularly valuable for the skin area because it is rich in magnesium and potassium. Magnesium is known as an antiallergen, an important building block for the structural elements of the skin and the enzymes that control the metabolism of the skin. Potassium is an important moisture regulator for the skin. Iodine has a disinfectant and healing effect. Chlorine and sodium are electrolytes dissolved in water and play an important role in
Regulierung des KörperSystems an Enzymen. Äußere Anwendungen erfolgen bei Schuppen, Akne, Ekzemen, Psoriasis und Neurodermitis wie auch bei anderen Hautkrankheiten und Hautirritationen. Es ist nachweislich festgestellt worden, daß als Sekundärerscheinung durch die Einwirkung höhererRegulation of the body system on enzymes. External applications are for dandruff, acne, eczema, psoriasis and neurodermatitis as well as other skin diseases and skin irritations. It has been proven that secondary effects from higher exposure
Salzkonzentrationen auf die Haut die Produktion von freien Aminosäuren gesteigert wird. Im Vordergrund der Reaktionen des Hautstoffwechsels steht jedoch die Aktivierung proteolytischer Abbauvorgänge von hochmolekularen Eiweißverbindungen. Die entstehenden Abbauprodukte sindSalt concentrations on the skin increases the production of free amino acids. In the foreground of the reactions of the skin metabolism, however, is the activation of proteolytic degradation processes of high-molecular protein compounds. The resulting breakdown products are
Peptide mit hormonartigen Wirkungen, so daß letztendlich die in die Haut eindringenden Ionen auf das Innere des Organismus wirken können, wie z.B. auf das Gefäßsystem, die glatte Muskulatur, auf das Verdauungssystem und auf das vegetativ- hor onelle System.Peptides with hormone-like effects, so that ultimately the ions penetrating the skin can act on the interior of the organism, e.g. on the vascular system, the smooth muscles, on the digestive system and on the autonomic system.
Die dritte Wirkstoffkomponente, Pflanzenbestandteile und Pflanzenauszüge, erlaubt durch die große Anzahl an Pflanzen mit ihren vielfältigen Wirkstoffen im Phytobereich auch unzählige Variationsmöglichkeiten für die neueThe third active ingredient component, plant components and plant extracts, also allows countless variation options for the new one due to the large number of plants with their diverse active ingredients in the phyto area
Wirkstoffkombination. Insbesondere auch deshalb, da in vielen Fällen nicht nur der Auszug einer Pflanze, sondern Auszüge von verschiedenen Pflanzen, in verschieden hohen Konzentrationen, Verwendung finden können.Active ingredient combination. In particular, because in many cases not only the extract of a plant, but extracts from different plants, in different heights Concentrations, can be used.
Da die Mischung von Kolostrumauszügen und Mineralien des Toten Meer Salzes bevorzugt im Hautbereich Anwendung findet, werden nachstehend, nicht abschließend, primär und sekundär hautpositive Wirkstoffe enthaltende Pflanzen, Pflanzenbestandteile und/oder Pflanzenauszüge und ihre Eigenschaften aufgelistet, die für die erfindungsgemäße Wirkstoffkombination geeignet sind:Since the mixture of colostrum extracts and minerals from the Dead Sea salt is preferably used in the skin area, plants, plant constituents and / or plant extracts and their properties which are suitable for the active compound combination according to the invention are listed below, but not exclusively, primarily and secondarily skin-active substances.
Aloe Vera stärkt die Selbstheilung der Haut,Aloe Vera strengthens the skin's self-healing,
Aprikosenpulver entfernt abgestorbene Hautzellen,Apricot powder removes dead skin cells,
Arnika fördert die Wundheilung,Arnica promotes wound healing,
Avocadoöl ist beruhigend und reizlindernd, Eukalyptus, Geranium, Myrrhe sind antiseptisch und antibakteriell ,Avocado oil is soothing and soothing, eucalyptus, geranium, myrrh are antiseptic and antibacterial,
Ginseng ist vitalisierend,Ginseng is vitalizing
Honig und Mandelöl sind entspannend und pflegend,Honey and almond oil are relaxing and nourishing,
Jojobaöl ist feuchtigkeitsspendend und nährend, Kamille und Lavendel sind entzündungshemmend,Jojoba oil is moisturizing and nourishing, chamomile and lavender are anti-inflammatory,
Nelkenöl ist schmerzlindernd,Clove oil is soothing,
Pfefferminzöl ist kühlend und erfrischend,Peppermint oil is cooling and refreshing,
Sonnenblumenöl enthält viele Vitamine A, D, B und E und wirkt pflegend, Teebaumöl ist entwässernd und wirkt antibakteriell.Sunflower oil contains many vitamins A, D, B and E and has a nourishing effect, tea tree oil is draining and has an antibacterial effect.
Es sind bei dieser Auflistung nur die wichtigsten Wirkungsweisen angegeben. Die meisten Auszüge haben eine Vielfalt an Inhaltsstoffen, die weitere Wirkungen entfalten können.Only the most important modes of action are given in this list. Most extracts have a variety of ingredients that can have further effects.
Kolostrum wirkt üblicherweise am stärksten bei Einnahme und ist bei äußerer Anwendung seine Wirkung nicht so nachhaltig. Dagegen ist die Wirkung des Toten Meer Salzes bei äußerlicher Anwendung besonders gesundheitsfördernd. Bei direkterColostrum usually has the greatest effect when ingested and its effects are not so long-lasting when used externally. On the other hand, the effect of the Dead Sea salt is particularly good for health when used externally. With direct
Anwendung des Toten Meer Salzes an der Haut des Menschen lösen sich die verhornten und schuppigen Stellen. Die Mineralien können in die oberen Hautschichten eindringen, wodurch die Haut nachhaltig angeregt, aufnahmefähiger und durchlässiger wird. Das hat weiter zur Folge, daß die sonst schwierige Aufnahme der feinsto flichenApplying the Dead Sea salt to the skin of the person loosens the keratinized and scaly areas. The minerals can penetrate the upper layers of the skin, which makes the skin lastingly stimulated, more receptive and more permeable. This also has the consequence that the otherwise difficult absorption of the fine materials
Kolostralmilchprodukte und/oder Kolostralmilchauszüge, wenn diese über die Haut aufgenommen werden sollen, durch die erfinderische Kombination mit Toten Meer Salz erleichtert und wesentlich verbessert wird. Auch eine verbesserte Aufnahme der Wirkstoffe beigemischter Pflanzenextrakte wird so erreicht.Colostral milk products and / or colostral milk extracts, if these are to be absorbed through the skin, are facilitated and substantially improved by the inventive combination with Dead Sea salt. An improved absorption of the active ingredients of admixed plant extracts is also achieved in this way.
Ein weiteres Beispiel eines solchen Synergieeffekt der erfindungsgemäßen Wirkstoffkombination wird nachstehend beschrieben.Another example of such a synergy effect of the active ingredient combination according to the invention is described below.
Bei Kamille reagiert ein Allergiker oft allergisch. Es ist inzwischen nachgewiesen, daß das Mineral Magnesium antiallergisch wirkt und einer allergischen Reaktion bei einer Anwendung mit Kamille entgegenwirkt. Somit ist eine Anwendung einer Wirkstoffkombination aus Kolostrum, Totes Meer Salz und Kamilleauszügen auch bei einem Kamille- Allergiker ermöglicht. Bei äußerlicher Anwendung als Salbe wirkt diese Wirkstoffkombination beruhigend und entzündungshemmend und erleichtert die Aufnahme wichtiger Stoffe in die Haut.An allergy to chamomile often reacts allergically. It has now been proven that the mineral magnesium has an anti-allergic effect and counteracts an allergic reaction when used with chamomile. This means that an active ingredient combination of colostrum, Dead Sea salt and chamomile extracts can also be used by a person who is allergic to chamomile. When used externally as an ointment, this combination of active ingredients has a calming and anti-inflammatory effect and facilitates the absorption of important substances into the skin.
Es ist festzuhalten, daß insbesondere in der Kombination und Vermengung von Kolostralmilchauszügen und/oder -produkten, Mineralien und/oder Mineralsalzen, insbesondere Totes Meer Salzmineralien, und pflanzlichen Auszügen und/oder Pflanzenbestandteilen ein neues komplettes Wirkstoffsystem für den Human- und Veterinärbereich gegeben ist.It should be noted that especially in the combination and blending of colostral milk extracts and / or products, minerals and / or mineral salts, in particular Dead Sea salt minerals, and herbal extracts and / or plant components, a new complete active ingredient system for the human and veterinary sector is given.
Kolostrum weist als Naturprodukt, dessen einmalige naturgegebene Rezeptur in Laboratorien kaum exakt imitiert werden dürfte, alle lebenswichtigen nichtessentiellen und essentiellen Aminosäuren, Immunglobuline und natürliche Wachstumsfaktoren nebst Vitaminen, Mineralstoffen und Laktose und eine Vielzahl an notwendigen Bau- und BetriebsstoffSubstanzen zur Erhaltung und zum Schutz des Lebens auf.As a natural product, whose unique natural recipe is unlikely to be exactly imitated in laboratories, colostrum has all the vital nonessential and essential amino acids, immunoglobulins and natural growth factors along with vitamins, minerals and lactose and a large number of necessary building materials Fuel substances for the preservation and protection of life.
Mineralien und/oder Mineralsalze, insbesondere Totes Meer Salz als weltweit in der Konzentration einmaliger Mineralgeber ergänzen die nicht oder nur in geringem Maß im Kolostrum enthaltenden Mineralien um einen weiteren Baustein für die Gesundheit, der insbesondere durch die Haut auf den gesamten Stoffwechsel des Menschen einwirken kann.Minerals and / or mineral salts, in particular Dead Sea salt as a mineral donor that is unique in the world, complement the minerals that do not contain or only to a small extent in colostrum by a further building block for health, which can affect the entire metabolism of humans, in particular through the skin .
Zuletzt wird in die erfindungsgemäße Wirkstoffkombination durch pflanzliche Extrakte und Auszüge vervollständigt und deren vielfältigen Wirkungsweisen gleichfalls genutzt. Finally, the active ingredient combination according to the invention is supplemented by herbal extracts and extracts, and their various modes of action are also used.

Claims

Patentansprüche: Claims:
1. Wirkstoff für Mensch und Tier, basierend auf Kolostralmilchprodukten und/oder Kolostralmilchauszügen von Mensch, Schaf und/oder Ziege.1. Active ingredient for humans and animals, based on colostral milk products and / or colostral milk extracts from humans, sheep and / or goats.
2. Wirkstoffkombination für Mensch und Tier, bestehend aus einer Mischung von Kolostralmilchprodukten und/oder Kolostralmilchauszügen, insbesondere nach Anspruch 1, von Mineralien und/oder Mineralsalzen und von Pflanzenbestandteilen und/oder Pflanzenauszügen.2. Active substance combination for humans and animals, consisting of a mixture of colostral milk products and / or colostral milk extracts, in particular according to claim 1, of minerals and / or mineral salts and of plant components and / or plant extracts.
3. Wirkstoffkombination nach Anspruch 2, gekennzeichnet durch Kolostralmilchprodukte und/oder3. Active ingredient combination according to claim 2, characterized by colostral milk products and / or
Kolostralmilchauszüge bovinen und/oder equinen Ursprungs.Colostrum extracts of bovine and / or equine origin.
4. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß der Anteil an Kolostralmilchprodukten und/oder4. Active ingredient combination according to one or more of the preceding claims, characterized in that the proportion of colostral milk products and / or
Kolostralmilchauszügen an der Wirkstoffkombination und/oder einem Endprodukt zwischen 0,1 und 60 Teilen von Hundert liegt.Colostral milk extracts on the active ingredient combination and / or an end product is between 0.1 and 60 parts of a hundred.
5. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche^ dadurch gekennzeichnet, daß die Kolostralmilchprodukte und/oder Kolostralmilchauszüge in flüssiger, fester, pastöser oder in verkapselter Form vorliegen.5. Active ingredient combination according to one or more of the preceding claims ^ characterized in that the colostral milk products and / or colostral milk extracts in liquid, solid, pasty or in encapsulated form available.
6. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Kolostralmilchprodukte und/oder Kolostralmilchauszüge verkapselt in Liposomen eingeschlossen vorliegt.6. Active ingredient combination according to one or more of the preceding claims, characterized in that the colostral milk products and / or colostral milk extracts are encapsulated in liposomes.
7. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Mineralien und/oder Mineralsalze in fester, flüssiger oder pastöser Form vorliegen.7. Active ingredient combination according to one or more of the preceding claims, characterized in that the minerals and / or mineral salts are present in solid, liquid or pasty form.
8. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Pflanzenbestandteile oder Pflanzenauszüge in fester, flüssiger oder pastöser Form vorliegen.8. Active ingredient combination according to one or more of the preceding claims, characterized in that the plant components or plant extracts are in solid, liquid or pasty form.
9. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, gekennzeichnet durch eine feste, flüssige oder pastöse Form9. Active ingredient combination according to one or more of the preceding claims, characterized by a solid, liquid or pasty form
10. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Wirkstoffkombination als Arzneimittel, Nahrungsmittel, Nahrungsergänzungsmittel oder Kosmetikum verwendet wird.10. Active ingredient combination according to one or more of the preceding claims, characterized in that the active ingredient combination is used as a medicament, food, dietary supplement or cosmetic.
11. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Wirkstoffkombination als Zusatz für Arzneimittel, Nahrungsmittel, Nahrungsergänzungsmittel, Getränke oder Kosmetika verwendet wird.11. Active ingredient combination according to one or more of the preceding claims, characterized in that the active ingredient combination is used as an additive for pharmaceuticals, foods, food supplements, beverages or cosmetics.
12. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Wirkstoffkombination als Bestandteil für Babynahrung, diätetischer Nahrung, JTinischer Nahrung oder für Sondernahrung verwendet wird. 12. Active ingredient combination according to one or more of the preceding claims, characterized in that the active ingredient combination is used as a component for baby food, dietary food, JTinische food or for special food.
3. Wirkstoffkombination nach einem oder mehreren der vorangehenden Ansprüche, dadurch gekennzeichnet, daß die Wirkstoffkombination als Zusatz zu Backwaren, energiehaltigen Riegeln, Müsliriegeln oder Powerbars, Gewürzen, Milchprodukten, Konfitüren, Gelees, Speiseölen, Speisefetten, Teesorten, Kaffee und Kaffeersatzmittel, Honig, Speiseeis, Salz, Senf oder Würzmitteln verwendet wird. 3. Active ingredient combination according to one or more of the preceding claims, characterized in that the active ingredient combination as an additive to baked goods, energy-containing bars, granola bars or power bars, spices, milk products, jams, jellies, edible oils, edible fats, teas, coffee and coffee substitutes, honey, ice cream , Salt, mustard or condiments is used.
PCT/DE2000/000929 1999-03-31 2000-03-29 Active agent and combination of active agents for human beings and animals WO2000059519A2 (en)

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AU47426/00A AU4742600A (en) 1999-03-31 2000-03-29 Active agent and combination of active agents for human beings and animals
EP00929249A EP1180940A2 (en) 1999-03-31 2000-03-29 Active agent and combination of active agents for human beings and animals

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE1999114646 DE19914646A1 (en) 1999-03-31 1999-03-31 Combination of active agents for humans and animals, e.g. for medicinal, nutritional or cosmetic use, comprises a colostral milk product or extract, minerals and plant components or extracts
DE19914646.2 1999-03-31
DE1999163628 DE19963628A1 (en) 1999-12-29 1999-12-29 Synergistic active agent combination of colostrum product, minerals and herbal component, useful as or in medicaments, foodstuffs, food supplements or cosmetics, e.g. for skin treatment
DE19963628.1 1999-12-29
DE2000100157 DE10000157A1 (en) 2000-01-06 2000-01-06 Synergistic active agent combination of colostrum product, minerals and herbal component, useful as or in medicaments, foodstuffs, food supplements or cosmetics, e.g. for skin treatment
DE10000157.2 2000-01-06

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WO2000059519A2 true WO2000059519A2 (en) 2000-10-12
WO2000059519A3 WO2000059519A3 (en) 2001-01-11

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US7557094B2 (en) * 2000-11-13 2009-07-07 Ethics Cosmeceuticals Ab Skin cream composition
US7169416B2 (en) 2001-05-23 2007-01-30 Nutricopia, Inc. Nutritional frozen dessert and methods of manufacture
WO2003011241A1 (en) * 2001-07-25 2003-02-13 Beiersdorf Ag Utilization of creatinine and/or creatinine derivatives in cosmetic and dermatological preparations
WO2003011242A1 (en) * 2001-07-25 2003-02-13 Beiersdorf Ag Cosmetic or dermatological preparations containing a combination of creatinine and/or creatinine derivatives and creatine and/or the derivatives thereof
US7033629B2 (en) 2001-08-31 2006-04-25 Nutricopia Inc. Nutritional frozen dessert and methods of manufacture
EP1727434A2 (en) * 2004-03-19 2006-12-06 Nestec S.A. Delivery of functional ingredients
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AU4742600A (en) 2000-10-23
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