WO2000049138A3 - Pluripotential cells derived from embryonal teratocarcinoma cells and the nucleus of stomatic cells - Google Patents

Pluripotential cells derived from embryonal teratocarcinoma cells and the nucleus of stomatic cells Download PDF

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Publication number
WO2000049138A3
WO2000049138A3 PCT/GB2000/000582 GB0000582W WO0049138A3 WO 2000049138 A3 WO2000049138 A3 WO 2000049138A3 GB 0000582 W GB0000582 W GB 0000582W WO 0049138 A3 WO0049138 A3 WO 0049138A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
nucleus
stomatic
pluripotential
derived
Prior art date
Application number
PCT/GB2000/000582
Other languages
French (fr)
Other versions
WO2000049138A2 (en
Inventor
Peter Andrews
Paul Kemp
Original Assignee
Univ Sheffield
Peter Andrews
Paul Kemp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Sheffield, Peter Andrews, Paul Kemp filed Critical Univ Sheffield
Priority to CA002371895A priority Critical patent/CA2371895A1/en
Priority to JP2000599864A priority patent/JP2002536976A/en
Priority to EP00903892A priority patent/EP1155118A2/en
Priority to AU25641/00A priority patent/AU2564100A/en
Publication of WO2000049138A2 publication Critical patent/WO2000049138A2/en
Publication of WO2000049138A3 publication Critical patent/WO2000049138A3/en
Priority to HK02102271.4A priority patent/HK1040532A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to isolated pluripotential cells comprising at least part of the cytoplasm from a teratocarcinoma cell and a nucleus of a somatic cell. The invention also relates to methods to prepare such cells.
PCT/GB2000/000582 1999-02-20 2000-02-18 Pluripotential cells derived from embryonal teratocarcinoma cells and the nucleus of stomatic cells WO2000049138A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002371895A CA2371895A1 (en) 1999-02-20 2000-02-18 Pluripotential cells-1
JP2000599864A JP2002536976A (en) 1999-02-20 2000-02-18 Pluripotent cells-1
EP00903892A EP1155118A2 (en) 1999-02-20 2000-02-18 Pluripotential cells derived from embryonal teratocarcinoma cells and the nucleus of somatic cells
AU25641/00A AU2564100A (en) 1999-02-20 2000-02-18 Pluripotential cells-1
HK02102271.4A HK1040532A1 (en) 1999-02-20 2002-03-26 Pluripotential cells derived from embryonal teratocarcinoma cells and the nucleus of somatic cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9903805.1 1999-02-20
GBGB9903805.1A GB9903805D0 (en) 1999-02-20 1999-02-20 Pluripotential cells-1

Publications (2)

Publication Number Publication Date
WO2000049138A2 WO2000049138A2 (en) 2000-08-24
WO2000049138A3 true WO2000049138A3 (en) 2001-02-22

Family

ID=10848085

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/000582 WO2000049138A2 (en) 1999-02-20 2000-02-18 Pluripotential cells derived from embryonal teratocarcinoma cells and the nucleus of stomatic cells

Country Status (7)

Country Link
EP (1) EP1155118A2 (en)
JP (1) JP2002536976A (en)
AU (1) AU2564100A (en)
CA (1) CA2371895A1 (en)
GB (1) GB9903805D0 (en)
HK (1) HK1040532A1 (en)
WO (1) WO2000049138A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0118984D0 (en) * 2001-08-03 2001-09-26 Intercytex Ltd Fusion of cells
US20030113910A1 (en) * 2001-12-18 2003-06-19 Mike Levanduski Pluripotent stem cells derived without the use of embryos or fetal tissue
US7785876B2 (en) 2002-11-14 2010-08-31 Aderans Research Institute, Inc. Cultivation of hair inductive cells
WO2007026255A2 (en) * 2005-06-22 2007-03-08 Universitetet I Oslo Dedifferentiated cells and methods of making and using dedifferentiated cells
US7922688B2 (en) 2007-01-08 2011-04-12 Restoration Robotics, Inc. Automated delivery of a therapeutic or cosmetic substance to cutaneous, subcutaneous and intramuscular tissue regions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007669A1 (en) * 1995-08-31 1997-03-06 Roslin Institute (Edinburgh) Quiescent cell populations for nuclear transfer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007669A1 (en) * 1995-08-31 1997-03-06 Roslin Institute (Edinburgh) Quiescent cell populations for nuclear transfer

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
FULKA J ET AL: "CLONING BY SOMATIC CELL NUCLEAR TRANSFER", MICROBIOLOGICAL REVIEWS,US,AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, vol. 20, 1998, pages 847 - 851, XP002900701, ISSN: 0146-0749 *
J A THOMSON ET AL: "EMBRYONIC STEM CELL LINES DERIVED FROM HUMAN BLASTOCYSTS", SCIENCE,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,,US, vol. 282, 6 November 1998 (1998-11-06), pages 1145 - 1147, XP002121340, ISSN: 0036-8075 *
TOSU M ET AL: "CLONAL ISOLATION AND CHARACTERIZATION OF MYOBLAST-LIKE RECONSTITUTED CELLS FORMED BY FUSION OF KARYOPLASTS FROM MOUSE TERATOCARCINOMA CELLS WITH RAT MYOBLAST CYTOPLASTS", CELL STRUCTURE AND FUNCTION, vol. 13, no. 3, 1988, pages 249 - 266, XP000939352, ISSN: 0386-7196 *
WANGH LAWRENCE J ET AL: "Efficient reactivation of Xenopus erythrocyte nuclei in Xenopus egg extracts.", JOURNAL OF CELL SCIENCE, vol. 108, no. 6, 1995, pages 2187 - 2196, XP000939319, ISSN: 0021-9533 *
YEOM ET AL: "Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells", DEVELOPMENT,GB,COLCHESTER, ESSEX, vol. 122, 1996, pages 881 - 894, XP002094592, ISSN: 0950-1991 *

Also Published As

Publication number Publication date
AU2564100A (en) 2000-09-04
HK1040532A1 (en) 2002-06-14
GB9903805D0 (en) 1999-04-14
WO2000049138A2 (en) 2000-08-24
EP1155118A2 (en) 2001-11-21
JP2002536976A (en) 2002-11-05
CA2371895A1 (en) 2000-08-24

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