WO1999053075A3 - Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants - Google Patents

Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants Download PDF

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Publication number
WO1999053075A3
WO1999053075A3 PCT/US1999/007638 US9907638W WO9953075A3 WO 1999053075 A3 WO1999053075 A3 WO 1999053075A3 US 9907638 W US9907638 W US 9907638W WO 9953075 A3 WO9953075 A3 WO 9953075A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell cycle
cycle regulatory
cdc
plants
regulatory proteins
Prior art date
Application number
PCT/US1999/007638
Other languages
French (fr)
Other versions
WO1999053075A2 (en
Inventor
Theodore M Klein
Layo O Morakinyo
Joan T Odell
Hajime Sakai
Original Assignee
Du Pont
Theodore M Klein
Layo O Morakinyo
Joan T Odell
Hajime Sakai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Theodore M Klein, Layo O Morakinyo, Joan T Odell, Hajime Sakai filed Critical Du Pont
Priority to EP99916470A priority Critical patent/EP1068334A2/en
Priority to AU34783/99A priority patent/AU3478399A/en
Publication of WO1999053075A2 publication Critical patent/WO1999053075A2/en
Publication of WO1999053075A3 publication Critical patent/WO1999053075A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

This invention relates to an isolated nucleic acid fragment encoding a cell cycle regulatory protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the cell cycle regulatory protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the cell cycle regulatory protein in a transformed host cell.
PCT/US1999/007638 1998-04-09 1999-04-08 Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants WO1999053075A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99916470A EP1068334A2 (en) 1998-04-09 1999-04-08 Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants
AU34783/99A AU3478399A (en) 1998-04-09 1999-04-08 Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8113298P 1998-04-09 1998-04-09
US60/081,132 1998-04-09

Publications (2)

Publication Number Publication Date
WO1999053075A2 WO1999053075A2 (en) 1999-10-21
WO1999053075A3 true WO1999053075A3 (en) 2000-03-23

Family

ID=22162293

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1999/007638 WO1999053075A2 (en) 1998-04-09 1999-04-08 Cell cycle regulatory proteins cdc-16, dp-1, dp-2 and e2f from plants
PCT/US1999/007640 WO1999053069A2 (en) 1998-04-09 1999-04-08 Cell cycle regulatory proteins cdc2 and pitslre from plants

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US1999/007640 WO1999053069A2 (en) 1998-04-09 1999-04-08 Cell cycle regulatory proteins cdc2 and pitslre from plants

Country Status (4)

Country Link
EP (2) EP1068334A2 (en)
AR (2) AR015757A1 (en)
AU (2) AU3478599A (en)
WO (2) WO1999053075A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000047614A1 (en) * 1999-02-12 2000-08-17 Pioneer Hi-Bred International, Inc. Transgenic plants with modified expression of the dp protein
BR0014634A (en) * 1999-09-24 2003-02-25 Consejo Superior Investigacion Wheat proteins and their use
CA2374431A1 (en) * 1999-09-27 2001-04-05 Pioneer Hi-Bred International, Inc. Enhanced stress tolerance in maize via manipulation of cell cycle regulatory genes
GB9923306D0 (en) 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
GB0212885D0 (en) 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
AU2005237287B2 (en) 2004-04-28 2011-08-11 Btg International Limited Epitopes related to coeliac disease
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
US7825293B2 (en) 2004-05-28 2010-11-02 Cropdesign N.V. Plants having improved growth characteristics and a method for making the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010307A1 (en) * 1992-10-29 1994-05-11 Medical Research Council Transcription factor dp-1
WO1996001425A2 (en) * 1994-07-01 1996-01-18 Medical Research Council Assay for inhibitors of dp-1 and other dp proteins
WO1997043647A1 (en) * 1996-05-15 1997-11-20 Medical Research Council Dp and e2f protein nuclear localisation signals and their use
WO1997047745A1 (en) * 1996-06-13 1997-12-18 Consejo Superior De Investigaciones Cientificas Plant retinoblastoma-associated proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294538A (en) * 1991-11-18 1994-03-15 Cold Spring Harbor Labs. Method of screening for antimitotic compounds using the CDC25 tyrosine phosphatase
US5821234A (en) * 1992-09-10 1998-10-13 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of proliferation of vascular smooth muscle cell
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010307A1 (en) * 1992-10-29 1994-05-11 Medical Research Council Transcription factor dp-1
WO1996001425A2 (en) * 1994-07-01 1996-01-18 Medical Research Council Assay for inhibitors of dp-1 and other dp proteins
WO1997043647A1 (en) * 1996-05-15 1997-11-20 Medical Research Council Dp and e2f protein nuclear localisation signals and their use
WO1997047745A1 (en) * 1996-06-13 1997-12-18 Consejo Superior De Investigaciones Cientificas Plant retinoblastoma-associated proteins

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
COLASANTI J ET AL.: "Isolation and characterization of cDNA clones encoding a functional p34cdc2 homologue from Zea mays", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 88, April 1991 (1991-04-01), pages 3377 - 3381, XP002113194 *
DATABASE EMHTG EMBL Heidelberg, Germany; 16 November 1998 (1998-11-16), NAKAMURA Y: "Structural analysis of Arabidopsis thaliana chromosome 5", XP002127847 *
DATABASE EMHTG EMBL, Heidelberg, Germany; 31 October 1997 (1997-10-31), NAKAMURA Y ET AL.: "Structural analysis of Arabidopsis thaliana chromosome 5", XP002127845 *
DATABASE R57U036 EMBL, Heidelberg, Germany; 3 February 1998 (1998-02-03), NAKAMURA Y: "Structural analysis of Arabidopsis thaliana chromosome 5", XP002127846 *
DATABASE R58U022 EMBL, Heidelberg, Germany; 17 March 1999 (1999-03-17), ALCALA J ET AL.: "Generation of ESTs from tomato carpel tissue", XP002127848 *
DUDITS ET AL: "Cyclin-dependent and calcium-dependent kinase families: response of cell division cycle to hormone and stress signals", PORTLAND PRESS RESEARCH MONOGRAPH, 1996, pages 21 - 45, XP002080506, ISSN: 0964-5845 *
HASHIMOTO J ET AL.: "Isolation and characterization of cDNA clones encoding cdc2 homologues from Oryza sativa: a functional homologue and cognate variants", MOLECULAR AND GENERAL GENETICS, vol. 233, no. 1-2, May 1992 (1992-05-01), pages 10 - 16, XP002113196 *
LAMB J R ET AL: "CDC16P, CDC23P AND CDC27P FORM A COMPLEX ESSENTIAL FOR MITOSIS", EMBO JOURNAL, vol. 13, no. 18, 15 September 1994 (1994-09-15), pages 4321 - 4328, XP002030313, ISSN: 0261-4189 *
MIAO G-H ET AL.: "Two functional soybean genes encoding p34cdc2 protein kinases are regulated by different plant developmental pathways", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 90, February 1993 (1993-02-01), pages 943 - 947, XP002113195 *
VEYLDER DE L ET AL: "THE ARABIDOPSIS CKS1 AT PROTEIN BINDS THE CYCLIN-DEPENDENT KINASES CDC2AAT AND CDC2BAT", FEBS LETTERS, vol. 412, no. 3, 4 August 1997 (1997-08-04), pages 446 - 452, XP002047992, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
WO1999053069A2 (en) 1999-10-21
WO1999053069A3 (en) 2000-03-23
EP1068334A2 (en) 2001-01-17
EP1068335A2 (en) 2001-01-17
AR015757A1 (en) 2001-05-16
AR015756A1 (en) 2001-05-16
AU3478399A (en) 1999-11-01
WO1999053075A2 (en) 1999-10-21
AU3478599A (en) 1999-11-01

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